-
1
-
-
33646352962
-
Potent antibody therapeutics by design
-
Carter PJ. Potent antibody therapeutics by design. Nat Rev Immunol 2006;6:343-357.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 343-357
-
-
Carter, P.J.1
-
2
-
-
41549127546
-
Antibodies-Europe. Engineering the next generation of antibodies
-
Moutel S, Perez F. "Antibodies-Europe. Engineering the next generation of antibodies". Biotechnol J 2008;3:298-300
-
(2008)
Biotechnol J
, vol.3
, pp. 298-300
-
-
Moutel, S.1
Perez, F.2
-
3
-
-
34247876138
-
Development trends for monoclonal antibody cancer therapeutics
-
DOI 10.1038/nrd2241, PII NRD2241
-
Reichert JM, Valge-Archer VE. Development trends for monoclonal antibody cancer therapeutics. Nat Rev Drug Discov 2007;6:349-356 (Pubitemid 46696550)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.5
, pp. 349-356
-
-
Reichert, J.M.1
Valge-Archer, V.E.2
-
4
-
-
13544276336
-
Glycosylation of recombinant antibody therapeutics
-
DOI 10.1021/bp040016j
-
Jefferis R. Glycosylation of Recombinant Antibody Therapeutics. Biotechnol Prog 2005;21:11-16 (Pubitemid 40218466)
-
(2005)
Biotechnology Progress
, vol.21
, Issue.1
, pp. 11-16
-
-
Jefferis, R.1
-
5
-
-
34748865088
-
Antibody therapeutics: Isotype and glycoform selection
-
DOI 10.1517/14712598.7.9.1401
-
Jefferis R. Antibody therapeutics: isotype and glycoform selection. Expert Opin Biol Ther 2007;7:1401-1413 (Pubitemid 47475656)
-
(2007)
Expert Opinion on Biological Therapy
, vol.7
, Issue.9
, pp. 1401-1413
-
-
Jefferis, R.1
-
6
-
-
35748949531
-
Optimizing engagement of the immune system by anti-tumor antibodies: An engineer's perspective
-
DOI 10.1016/j.drudis.2007.08.009, PII S1359644607003509
-
Desjarlais JR, Lazar GA, Zhukovsky EA, Chu SY. Optimizing engagement of the immune system by anti-tumor antibodies: an engineer's perspective. Drug Discov Today 2007;12:898-910 (Pubitemid 350052671)
-
(2007)
Drug Discovery Today
, vol.12
, Issue.21-22
, pp. 898-910
-
-
Desjarlais, J.R.1
Lazar, G.A.2
Zhukovsky, E.A.3
Chu, S.Y.4
-
7
-
-
25444435396
-
Glycoengineering: The effect of glycosylation on the properties of therapeutic proteins
-
DOI 10.1002/jps.20319
-
Sinclair AM, Elliott SJ. Glycoengineering: The effect of glycosylation on the properties of therapeutic proteins. Pharm Sci 2005;94:626-1635 (Pubitemid 41360859)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.8
, pp. 1626-1635
-
-
Sinclair, A.M.1
Elliott, S.2
-
8
-
-
0037178791
-
Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human FcγRIII and antibody-dependent cellular toxicity
-
DOI 10.1074/jbc.M202069200
-
Shields RL, et al. Lack of Fucose on Human IgG1 N-Linked oligosaccharide improves binding to human FcγRIII and Antibody-dependent cellular toxicity. J Biol Chem 2002;277:26733-26740 (Pubitemid 34951677)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.30
, pp. 26733-26740
-
-
Shields, R.L.1
Lai, J.2
Keck, R.3
O'Connell, L.Y.4
Hong, K.5
Gloria Meng, Y.6
Weikert, S.H.A.7
Presta, L.G.8
-
9
-
-
0037474276
-
The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity
-
DOI 10.1074/jbc.M210665200
-
Shinkawa T, et al. The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity. J Biol Chem 2003;278:3466-3473 (Pubitemid 36801263)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.5
, pp. 3466-3473
-
-
Shinkawa, T.1
Nakamura, K.2
Yamane, N.3
Shoji-Hosaka, E.4
Kanda, Y.5
Sakurada, M.6
Uchida, K.7
Anazawa, H.8
Satoh, M.9
Yamasaki, M.10
Hanai, N.11
Shitara, K.12
-
10
-
-
28444495153
-
297-linked oligosaccharides
-
DOI 10.1016/j.jim.2005.08.009, PII S0022175905002838
-
Niwa R, et al. IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides. J Immunol Methods 2005;306:151-160 (Pubitemid 41739846)
-
(2005)
Journal of Immunological Methods
, vol.306
, Issue.1-2
, pp. 151-160
-
-
Niwa, R.1
Natsume, A.2
Uehara, A.3
Wakitani, M.4
Iida, S.5
Uchida, K.6
Satoh, M.7
Shitara, K.8
-
11
-
-
33646070900
-
Modulation of therapeutic antibody effector functions by glycosylation engineering: Influence of Golgi enzyme localization domain and co-expression of heterologous beta1, 4-N-acetylglucosaminyltransferase III and Golgi alpha-mannosidase II
-
Ferrara C, et al. Modulation of therapeutic antibody effector functions by glycosylation engineering: influence of Golgi enzyme localization domain and co-expression of heterologous beta1, 4-N-acetylglucosaminyltransferase III and Golgi alpha-mannosidase II. Biotechnol Bioeng 2006;93:851-861
-
(2006)
Biotechnol Bioeng
, vol.93
, pp. 851-861
-
-
Ferrara, C.1
-
12
-
-
1142298744
-
Human antibody-Fc receptor interactions illuminated by crystal structures
-
Woof JM, Burton DR. Human antibody-Fc receptor interactions illuminated by crystal structures. Nat Rev Immunol 2004;4:89-99 (Pubitemid 38209203)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.2
, pp. 89-99
-
-
Woof, J.M.1
Burton, D.R.2
-
13
-
-
1142286441
-
Interactions of Immunoglobulins Outside the Antigen-Combining Site
-
DOI 10.1016/S0065-2776(04)82004-2
-
Nezlin R, Ghetie V. Interactions of immunoglobulins outside the antigen-combining site. Adv Immunol 2004;82:155-215 (Pubitemid 38209511)
-
(2004)
Advances in Immunology
, vol.82
, pp. 155-215
-
-
Nezlin, R.1
Ghetie, V.2
-
14
-
-
0037474543
-
Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity
-
DOI 10.1016/S0022-2836(02)01250-0
-
Krapp S, et al. Structural analysis of human IgG glycoforms reveals a correlation between oligosaccharide content, structural integrity and Fcγ-receptor affi nity. J Mol Biol 2003;325:979-989 (Pubitemid 36263407)
-
(2003)
Journal of Molecular Biology
, vol.325
, Issue.5
, pp. 979-989
-
-
Krapp, S.1
Mimura, Y.2
Jefferis, R.3
Huber, R.4
Sondermann, P.5
-
15
-
-
0035794194
-
High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R
-
Shields RL, et al. High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J Biol Chem 2002;276:6591-6604
-
(2002)
J Biol Chem
, vol.276
, pp. 6591-6604
-
-
Shields, R.L.1
-
16
-
-
39149106011
-
Structural characterization of a mutated, ADCC-enhanced human Fc fragment
-
Oganesyan V, et al. Structural characterization of a mutated, ADCC-enhanced human Fc fragment. Mol Immunol 2008;45:1872-1882
-
(2008)
Mol Immunol
, vol.45
, pp. 1872-1882
-
-
Oganesyan, V.1
|