-
1
-
-
0032512094
-
Pathophysiology of progressive nephropathies
-
Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med. 1998;339:1448-1456.
-
(1998)
N Engl J Med
, vol.339
, pp. 1448-1456
-
-
Remuzzi, G.1
Bertani, T.2
-
2
-
-
0034048667
-
The role of protein traffic in the progression of renal diseases
-
Ruggenenti P, Remuzzi G. The role of protein traffic in the progression of renal diseases. Annu Rev Med. 2000;51:315-327.
-
(2000)
Annu Rev Med
, vol.51
, pp. 315-327
-
-
Ruggenenti, P.1
Remuzzi, G.2
-
3
-
-
0035154129
-
Mechanisms of albumin uptake by proximal tubular cells
-
Brunskill NJ. Mechanisms of albumin uptake by proximal tubular cells. Am J Kidney Dis. 2001;37:S17-S20.
-
(2001)
Am J Kidney Dis
, vol.37
-
-
Brunskill, N.J.1
-
4
-
-
0031682715
-
Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats
-
Ng YY, Huang TP, Yang WC, et al. Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats. Kidney Int. 1998;54:864-876.
-
(1998)
Kidney Int
, vol.54
, pp. 864-876
-
-
Ng, Y.Y.1
Huang, T.P.2
Yang, W.C.3
-
5
-
-
0036233005
-
Gene expression profile of renal proximal tubules regulated by proteinuria
-
Nakajima H, Takenaka M, Kaimori J, et al. Gene expression profile of renal proximal tubules regulated by proteinuria. Kidney Int. 2002;61:1577-1587.
-
(2002)
Kidney Int
, vol.61
, pp. 1577-1587
-
-
Nakajima, H.1
Takenaka, M.2
Kaimori, J.3
-
6
-
-
33846867674
-
Gene expression profiles of human proximal tubular epithelial cells in proteinuric nephropathies
-
Rudnicki M, Eder S, Perco P, et al. Gene expression profiles of human proximal tubular epithelial cells in proteinuric nephropathies. Kidney Int. 2007;71:325-335.
-
(2007)
Kidney Int
, vol.71
, pp. 325-335
-
-
Rudnicki, M.1
Eder, S.2
Perco, P.3
-
7
-
-
34447622488
-
Albumin overload induces adaptative responses in human proximal tubular cells through oxidative stress but not via angiotensin II type 1 receptor
-
Shalamanova L, McArdle F, Amara AB, Jackson MJ, Rustom R. Albumin overload induces adaptative responses in human proximal tubular cells through oxidative stress but not via angiotensin II type 1 receptor. Am J Physiol Renal Physiol. 2007;292:F1846-F1857.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Shalamanova, L.1
McArdle, F.2
Amara, A.B.3
Jackson, M.J.4
Rustom, R.5
-
8
-
-
0345223482
-
Albumin regulates the Na+/H+ exchanger 3 in OKP cells
-
Klisic J, Zhang J, Nief V, Reyes L, Moe OW, Ambühl PM. Albumin regulates the Na+/H+ exchanger 3 in OKP cells. J Am Soc Nephrol. 2003;14:3008-3016.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 3008-3016
-
-
Klisic, J.1
Zhang, J.2
Nief, V.3
Reyes, L.4
Moe, O.W.5
Ambühl, P.M.6
-
9
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Ann Rev Biochem. 1993;62:385-427.
-
(1993)
Ann Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
10
-
-
7544237299
-
The ABC transporters MDR1 and MRP2: Multiple functions in disposition of xenobiotics and drug resistance
-
Hoffmann U, Kroemer HK. The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance. Drug Metab Rev. 2004;36:669-701.
-
(2004)
Drug Metab Rev
, vol.36
, pp. 669-701
-
-
Hoffmann, U.1
Kroemer, H.K.2
-
11
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci. 1987;84:7735-7738.
-
(1987)
Proc Natl Acad Sci
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
12
-
-
0031949071
-
P-glycoprotein functions and substrates: Possible roles of MDR1 gene in the kidney
-
Ernest S, Bello-Reuss E. P-glycoprotein functions and substrates: possible roles of MDR1 gene in the kidney. Kidney Int. 1998;53:S11-S17.
-
(1998)
Kidney Int
, vol.53
-
-
Ernest, S.1
Bello-Reuss, E.2
-
13
-
-
3242785620
-
Importance of P-glycoprotein at blood-tissue barriers
-
Fromm MF. Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol Sci. 2004;25:423-429.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 423-429
-
-
Fromm, M.F.1
-
14
-
-
0028010818
-
HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney
-
Ryan M, Johnson G, Kirk J, et al. HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int. 1994;45:48-57.
-
(1994)
Kidney Int
, vol.45
, pp. 48-57
-
-
Ryan, M.1
Johnson, G.2
Kirk, J.3
-
16
-
-
0036406826
-
Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line
-
Romiti N, Tramonti G, Chieli E. Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line. Toxicol Appl Pharmacol. 2002;183:83-91.
-
(2002)
Toxicol Appl Pharmacol
, vol.183
, pp. 83-91
-
-
Romiti, N.1
Tramonti, G.2
Chieli, E.3
-
17
-
-
7544245330
-
Effects of grape-fruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2
-
Romiti N, Tramonti G, Donati A, Chieli E. Effects of grape-fruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2. Life Sci. 2004;76:293-302.
-
(2004)
Life Sci
, vol.76
, pp. 293-302
-
-
Romiti, N.1
Tramonti, G.2
Donati, A.3
Chieli, E.4
-
18
-
-
33750957352
-
Expression and functional characteristics of tubular transporters: P-glycoprotein, PEPT1, and PEPT2 in renal mass reduction and diabetes
-
Tramonti G, Xie P, Wallner EI, Danesh FR, Kanwar YS. Expression and functional characteristics of tubular transporters: P-glycoprotein, PEPT1, and PEPT2 in renal mass reduction and diabetes. Am J Physiol Renal Physiol. 2006;291:972-980.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
, pp. 972-980
-
-
Tramonti, G.1
Xie, P.2
Wallner, E.I.3
Danesh, F.R.4
Kanwar, Y.S.5
-
19
-
-
0025730640
-
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
-
Andrews NC, Faller DV. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 1991;19:2499.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 2499
-
-
Andrews, N.C.1
Faller, D.V.2
-
20
-
-
0031749820
-
-
Zoja C, Donadelli R, Colleoni S, 20. et al. Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kB activation. Kidney Int. 1998;53:1608-1615.
-
Zoja C, Donadelli R, Colleoni S, 20. et al. Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kB activation. Kidney Int. 1998;53:1608-1615.
-
-
-
-
21
-
-
33845408122
-
Increased L-arginine transport via system b0,+ in human proximal tubular cells exposed to albumin
-
Ashman N, Brunini TM, Mann GE, Mendes Ribeiro AC, Yaqoob MM. Increased L-arginine transport via system b0,+ in human proximal tubular cells exposed to albumin. Clin Sci. 2006;111:389-399.
-
(2006)
Clin Sci
, vol.111
, pp. 389-399
-
-
Ashman, N.1
Brunini, T.M.2
Mann, G.E.3
Mendes Ribeiro, A.C.4
Yaqoob, M.M.5
-
22
-
-
15544373016
-
Renal tubule albumin transport
-
Gekle M. Renal tubule albumin transport. Annu Rev Physiol. 2005;67:573-594.
-
(2005)
Annu Rev Physiol
, vol.67
, pp. 573-594
-
-
Gekle, M.1
-
23
-
-
21644461548
-
Albumin turns on a vicious spiral on oxidative stress in renal proximal tubules
-
Imai E, Nakajima H, Kaimori J. Albumin turns on a vicious spiral on oxidative stress in renal proximal tubules. Kidney Int. 2004;66:2085-2087.
-
(2004)
Kidney Int
, vol.66
, pp. 2085-2087
-
-
Imai, E.1
Nakajima, H.2
Kaimori, J.3
-
24
-
-
33750736645
-
How does proteinuria cause progressive renal damage?
-
Abbate M, Zoja C, Remuzzi G. How does proteinuria cause progressive renal damage? J Am Soc Nephrol. 2006;17:2974-2984.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2974-2984
-
-
Abbate, M.1
Zoja, C.2
Remuzzi, G.3
-
25
-
-
0033653377
-
Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation
-
Donadelli R, Abbate M, Zanchi C, et al. Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation. Am J Kidney Dis. 2000;36:1226-1241.
-
(2000)
Am J Kidney Dis
, vol.36
, pp. 1226-1241
-
-
Donadelli, R.1
Abbate, M.2
Zanchi, C.3
-
26
-
-
0036235016
-
Protein overload-induced NF-kB activation in proximal tubular cells requires H2O2 through a PKC-dependent pathway
-
Morigi M, Macconi D, Zoja C, et al. Protein overload-induced NF-kB activation in proximal tubular cells requires H2O2 through a PKC-dependent pathway. J Am Soc Nephrol. 2002;13:1179-1189.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1179-1189
-
-
Morigi, M.1
Macconi, D.2
Zoja, C.3
-
27
-
-
0035963663
-
Albumin in the mg/l-range activates NF-kappaB in renal proximal tubule-derived cell lines via tyrosine kinases and protein kinase C
-
Drumm K, Gassner B, Silbernagl S, Gekle M. Albumin in the mg/l-range activates NF-kappaB in renal proximal tubule-derived cell lines via tyrosine kinases and protein kinase C. Eur J Med Res. 2001;6:247-258.
-
(2001)
Eur J Med Res
, vol.6
, pp. 247-258
-
-
Drumm, K.1
Gassner, B.2
Silbernagl, S.3
Gekle, M.4
-
28
-
-
0036389459
-
Albumin induces NF-kB expression in human proximal tubule-derived cells (IHKE-1)
-
Drumm K, Bauer B, Freudinger R, Gekle M. Albumin induces NF-kB expression in human proximal tubule-derived cells (IHKE-1). Cell Physiol Biochem. 2002;12:187-196.
-
(2002)
Cell Physiol Biochem
, vol.12
, pp. 187-196
-
-
Drumm, K.1
Bauer, B.2
Freudinger, R.3
Gekle, M.4
-
29
-
-
0034740805
-
NF-kappaB and AP-1 activation in human proteinuric renal disease
-
Mezzano SA, Barria M, Droguett MA, et al. NF-kappaB and AP-1 activation in human proteinuric renal disease. Kidney Int. 2001;60:1366-1377.
-
(2001)
Kidney Int
, vol.60
, pp. 1366-1377
-
-
Mezzano, S.A.1
Barria, M.2
Droguett, M.A.3
-
30
-
-
34047212211
-
Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells
-
Erkan E, Devarajan P, Schwartz GJ. Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells. J Am Soc Nephrol. 2007;18:1199-1208.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1199-1208
-
-
Erkan, E.1
Devarajan, P.2
Schwartz, G.J.3
-
31
-
-
0034695660
-
Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis
-
Thévenod F, Friedmann JM, Katsen AD, Hauser IA. Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. J Biol Chem. 2000;275:1887-1896.
-
(2000)
J Biol Chem
, vol.275
, pp. 1887-1896
-
-
Thévenod, F.1
Friedmann, J.M.2
Katsen, A.D.3
Hauser, I.A.4
-
32
-
-
0030609891
-
NF-kappaB-mediated induction of mdr1b expression by insulin in rat hepatoma cells
-
Zhou G, Kuo MT. NF-kappaB-mediated induction of mdr1b expression by insulin in rat hepatoma cells. J Biol Chem. 1997;272:15174-15183.
-
(1997)
J Biol Chem
, vol.272
, pp. 15174-15183
-
-
Zhou, G.1
Kuo, M.T.2
-
33
-
-
0033573850
-
Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kB7p65 and c-Fos transcription factors and their interaction with the CAAT region
-
Ogretmen B, Safa AR. Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kB7p65 and c-Fos transcription factors and their interaction with the CAAT region. Biochemistry. 1999;38:2189-2199.
-
(1999)
Biochemistry
, vol.38
, pp. 2189-2199
-
-
Ogretmen, B.1
Safa, A.R.2
-
34
-
-
0034951265
-
Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients
-
Koziolek MJ, Riess R, Geiger H, Thevenod F, Hauser IA. Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. Kidney Int. 2001;60:156-166.
-
(2001)
Kidney Int
, vol.60
, pp. 156-166
-
-
Koziolek, M.J.1
Riess, R.2
Geiger, H.3
Thevenod, F.4
Hauser, I.A.5
-
35
-
-
0034994147
-
Induction of Mdr1b expression by tumor necrosis factor-a in rat liver cells is independent of p53 but requires NF-kB signaling
-
Ros JE, Schuetz JD, Geuken M, et al. Induction of Mdr1b expression by tumor necrosis factor-a in rat liver cells is independent of p53 but requires NF-kB signaling. Hepatology. 2001; 33:1425-1431.
-
(2001)
Hepatology
, vol.33
, pp. 1425-1431
-
-
Ros, J.E.1
Schuetz, J.D.2
Geuken, M.3
-
36
-
-
33751350541
-
The role of TNF-α in diabetic nephropathy: Pathogenic and therapeutic implications
-
Navarro JF, Mora-Fernández C. The role of TNF-α in diabetic nephropathy: pathogenic and therapeutic implications. Cytokine Growth Factor Rev. 2006;17:441-450.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 441-450
-
-
Navarro, J.F.1
Mora-Fernández, C.2
-
37
-
-
0033623536
-
-
Makarov SS. NF-κB as a therapeutic target in chronic inflammation: recent advances. Mol Med Today. 2000;6:441-448.
-
Makarov SS. NF-κB as a therapeutic target in chronic inflammation: recent advances. Mol Med Today. 2000;6:441-448.
-
-
-
-
38
-
-
2442690211
-
Degradation of albumin by the renal proximal tubule cells and the subsequent fate of its fragments
-
Gudehithlu KP, Pegoraro AA, Dunea G, Arruda JA, Singh AK. Degradation of albumin by the renal proximal tubule cells and the subsequent fate of its fragments. Kidney Int. 2004;65:2113-2122.
-
(2004)
Kidney Int
, vol.65
, pp. 2113-2122
-
-
Gudehithlu, K.P.1
Pegoraro, A.A.2
Dunea, G.3
Arruda, J.A.4
Singh, A.K.5
-
39
-
-
33646708967
-
Regulated intramembrane proteolysis of megalin: Linking urinary protein and gene regulation in proximal tubule?
-
Biemesderfer D. Regulated intramembrane proteolysis of megalin: linking urinary protein and gene regulation in proximal tubule? Kidney Int. 2005;69:1717-1721.
-
(2005)
Kidney Int
, vol.69
, pp. 1717-1721
-
-
Biemesderfer, D.1
-
40
-
-
0033799839
-
Multidrug resistance (MDR) in cancer: Mechanism, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs
-
Krishna R, Mayer LD. Multidrug resistance (MDR) in cancer: mechanism, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm. 2000;11:265-283.
-
(2000)
Eur J Pharm
, vol.11
, pp. 265-283
-
-
Krishna, R.1
Mayer, L.D.2
-
41
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug transporting) P-glycoproteins
-
Schinkel AH, Mayer U, Wagenaar E, et al. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug transporting) P-glycoproteins. Proc Natl Acad Sci. 1997;94:4028-4033.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.H.1
Mayer, U.2
Wagenaar, E.3
-
42
-
-
33748433791
-
Role of P-glycoprotein in cyclosporine toxicity in the cyclosporine-sirolimus interaction
-
Anglicheau D, Pallet N, Rabant M, et al. Role of P-glycoprotein in cyclosporine toxicity in the cyclosporine-sirolimus interaction. Kidney Int. 2006;70:1019-1025.
-
(2006)
Kidney Int
, vol.70
, pp. 1019-1025
-
-
Anglicheau, D.1
Pallet, N.2
Rabant, M.3
-
43
-
-
13144293094
-
Role of p-glycoprotein in chronic cyclosporine nephrotoxicity and its relationship to intrarenal angiotensin II deposits
-
Del Moral R, Olmo A, Osuna A, et al. Role of p-glycoprotein in chronic cyclosporine nephrotoxicity and its relationship to intrarenal angiotensin II deposits. Transplant Proc. 1998;30:2014-2016.
-
(1998)
Transplant Proc
, vol.30
, pp. 2014-2016
-
-
Del Moral, R.1
Olmo, A.2
Osuna, A.3
-
44
-
-
21444449731
-
ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation
-
Hauser IA, Schaeffeler E, Gauer S, et al. ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation. J Am Soc Nephrol. 2005;16:1501-1511.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1501-1511
-
-
Hauser, I.A.1
Schaeffeler, E.2
Gauer, S.3
-
45
-
-
0035146427
-
Albuminuria and renal injury: Beware of proteins bearing gifts
-
Iglesias J, Levine JS. Albuminuria and renal injury: beware of proteins bearing gifts. Nephrol Dial Transplant. 2001;16:215-218.
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 215-218
-
-
Iglesias, J.1
Levine, J.S.2
|