-
2
-
-
1242312903
-
Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells
-
Jiang C, Wang Z, Ganther H, and Lu J: Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells. Mol Cancer Ther 1, 1059-1066, 2002.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1059-1066
-
-
Jiang, C.1
Wang, Z.2
Ganther, H.3
Lu, J.4
-
3
-
-
0036306762
-
Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol
-
Wang Z, Jiang C, and Lu J: Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol. Mol Carcinog 34, 113-1112, 2002.
-
(2002)
Mol Carcinog
, vol.34
, pp. 113-1112
-
-
Wang, Z.1
Jiang, C.2
Lu, J.3
-
4
-
-
33644967001
-
Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells
-
WuY, Zu K,WarrenMA,Wallace PK, and Ip C:Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells. MolCancer Ther 5, 246-252, 2006.
-
(2006)
MolCancer Ther
, vol.5
, pp. 246-252
-
-
Wu, Y.1
Zu, K.2
Warren, M.A.3
Wallace, P.K.4
Ip, C.5
-
5
-
-
0141994828
-
Selenite-induced survival of HuH7 hepatoma cells involves activation of focal adhesion kinase-phosphatidylinositol 3-kinase-Akt pathway and Rac1
-
Lee YC, Tang YC, Chen YH, Wong CM, and Tsou AP: Selenite-induced survival of HuH7 hepatoma cells involves activation of focal adhesion kinase-phosphatidylinositol 3-kinase-Akt pathway and Rac1. J Biol Chem 278, 39615-39624, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 39615-39624
-
-
Lee, Y.C.1
Tang, Y.C.2
Chen, Y.H.3
Wong, C.M.4
Tsou, A.P.5
-
6
-
-
0033931514
-
A RedOx-inactive thioredoxin reduces growth and enhances apoptosis in WEHI7.2 cells
-
Freemerman AJ and Powis G: A RedOx-inactive thioredoxin reduces growth and enhances apoptosis in WEHI7.2 cells. Biochim Biophys Res Comm 274, 136-141, 2000.
-
(2000)
Biochim Biophys Res Comm
, vol.274
, pp. 136-141
-
-
Freemerman, A.J.1
Powis, G.2
-
7
-
-
0024393963
-
Thioredoxin and glutaredoxin systems
-
Holmgren A: Thioredoxin and glutaredoxin systems. J Biol Chem 264, 13963-13966, 1989.
-
(1989)
J Biol Chem
, vol.264
, pp. 13963-13966
-
-
Holmgren, A.1
-
8
-
-
0030731916
-
Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium
-
Gallegos A, Berggren M, Gasdaska JR, and Powis G: Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium. Cancer Res 57, 4965-4970, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 4965-4970
-
-
Gallegos, A.1
Berggren, M.2
Gasdaska, J.R.3
Powis, G.4
-
9
-
-
0033600744
-
Distinct roles of thioredoxin in the cytoplasm and in the nucleus: A two-step mechanism of RedOx regulation of transcription factor NF-kappaB
-
Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, et al.: Distinct roles of thioredoxin in the cytoplasm and in the nucleus: a two-step mechanism of RedOx regulation of transcription factor NF-kappaB. J Biol Chem 274, 27891-27897, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 27891-27897
-
-
Hirota, K.1
Murata, M.2
Sachi, Y.3
Nakamura, H.4
Takeuchi, J.5
-
10
-
-
0028344541
-
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1
-
Schenk H, Klein M, ErdbruggerW, DrogeW, and Schulze-Osthoff K: Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1. Proc Natl Acad Sci USA 91, 1672-1676, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1672-1676
-
-
Schenk, H.1
Klein, M.2
Erdbrugger, W.3
Droge, W.4
Schulze-Osthoff, K.5
-
11
-
-
0025077481
-
RedOx regulation of fos and jun DNA binding activity in vitro
-
Abate C, Patel L, Rauscher FJ 3rd, and Curran T: RedOx regulation of fos and jun DNA binding activity in vitro. Science 249, 1157-1161, 1990.
-
(1990)
Science
, vol.249
, pp. 1157-1161
-
-
Abate, C.1
Patel, L.2
Rauscher Iii, F.J.3
Curran, T.4
-
12
-
-
0033569457
-
Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: Thioredoxin inhibits protein kinase C-mediated phosphorylation of histone
-
Watson JA, Rumsby MG, and Wolowacz RG: Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: thioredoxin inhibits protein kinase C-mediated phosphorylation of histone. Biochem J 343, 301-305, 1999.
-
(1999)
Biochem J
, vol.343
, pp. 301-305
-
-
Watson, J.A.1
Rumsby, M.G.2
Wolowacz, R.G.3
-
13
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, et al.: Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17, 2596-2606, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
-
14
-
-
4143093730
-
Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: A mechanism for the functional loss of PTEN's tumor suppressor activity
-
Meuillet EJ, Mahadevan D, Berggren M, Coon A, and Powis G: Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. Arch Biochem Biophys 429, 123-133, 2004.
-
(2004)
Arch Biochem Biophys
, vol.429
, pp. 123-133
-
-
Meuillet, E.J.1
Mahadevan, D.2
Berggren, M.3
Coon, A.4
Powis, G.5
-
15
-
-
33947277986
-
The regulation of the tumor suppressor activity PTEN by thioredoxin controls cell number and cell size
-
Song Z, BrabantM, Saghafi N, Brabant M, andMeuillet EJ: The regulation of the tumor suppressor activity, PTEN by thioredoxin controls cell number and cell size. Exp Cell Res 313, 1161-1371, 2007.
-
(2007)
Exp Cell Res
, vol.313
, pp. 1161-1371
-
-
Song, Z.1
Brabant Saghafi M, N.2
Brabant, M.3
Meuillet, E.J.4
-
16
-
-
0035966127
-
Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex
-
Vazquez F, Grossman SR, Takahashi Y, Rokas MV, Nakamura N, et al.: Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex. J Biol Chem 276, 48627-48630, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 48627-48630
-
-
Vazquez, F.1
Grossman, S.R.2
Takahashi, Y.3
Rokas, M.V.4
Nakamura, N.5
-
17
-
-
0036644058
-
Negative feedback regulation of the tumor suppressor PTENby phosphoinositide-induced serine phosphorylation
-
Birle D, Bottini N, Williams S, Huynh H, deBelle I, et al.: Negative feedback regulation of the tumor suppressor PTENby phosphoinositide-induced serine phosphorylation. J Immunol 169, 286-291, 2002.
-
(2002)
J Immunol
, vol.169
, pp. 286-291
-
-
Birle, D.1
Bottini, N.2
Williams, S.3
Huynh, H.4
Debelle, I.5
-
18
-
-
34547490078
-
PTEN is destabilized by phosphorylation on Thr366
-
Maccario H, Perera NM, Davidson L, Downes P, and Leslie NR: PTEN is destabilized by phosphorylation on Thr366. Biochem J 405, 439-444, 2007.
-
(2007)
Biochem J
, vol.405
, pp. 439-444
-
-
MacCario, H.1
Perera, N.M.2
Davidson, L.3
Downes, P.4
Leslie, N.R.5
-
19
-
-
0033497080
-
Parallel syntheses of disulfide inhibitors of the thioredoxin RedOx system as potential antitumor agents
-
Kirkpatrick DL, Watson S, Kunkel M, Fletcher S, Ulhaq S, et al.: Parallel syntheses of disulfide inhibitors of the thioredoxin RedOx system as potential antitumor agents. Anticancer Drug Des 14, 421-432, 1999.
-
(1999)
Anticancer Drug des
, vol.14
, pp. 421-432
-
-
Kirkpatrick, D.L.1
Watson, S.2
Kunkel, M.3
Fletcher, S.4
Ulhaq, S.5
-
20
-
-
0033621042
-
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region
-
Georgescu MM, Kirsch KH, Akagi T, Shishido T, and Hanafusa H: The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proc Natl Acad Sci USA 96, 10182-10187, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10182-10187
-
-
Georgescu, M.M.1
Kirsch, K.H.2
Akagi, T.3
Shishido, T.4
Hanafusa, H.5
-
21
-
-
0028197077
-
Biochemical, structural and biological properties of human thioredoxin active site peptides
-
Oblong JE, Berggren M, and Powis G: Biochemical, structural and biological properties of human thioredoxin active site peptides. FEBS Lett 343, 81-84, 1993.
-
(1993)
FEBS Lett
, vol.343
, pp. 81-84
-
-
Oblong, J.E.1
Berggren, M.2
Powis, G.3
-
22
-
-
0034658104
-
A method for measuring disulfide reduction by cultured mammalian cells: Relative contributions of glutathione-dependent and glutathione-independent mechanisms
-
Biaglow JE, Donahue J, Tuttle S, Held K, Chrestensen C, et al.: A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms. Anal Biochem 281, 77-86, 2000.
-
(2000)
Anal Biochem
, vol.281
, pp. 77-86
-
-
Biaglow, J.E.1
Donahue, J.2
Tuttle, S.3
Held, K.4
Chrestensen, C.5
-
23
-
-
0029008623
-
Reduction and transport of lipoate by human erythrocytes
-
Constantinescu A, Pick U, Handelman GJ, Haramaki N, Han D, et al.: Reduction and transport of lipoate by human erythrocytes. Biochem Pharmacol 50, 253-261, 1995.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 253-261
-
-
Constantinescu, A.1
Pick, U.2
Handelman, G.J.3
Haramaki, N.4
Han, D.5
-
24
-
-
0032054899
-
A-Lipoate in liver metabolism and disease
-
Bustamante J, Lodge JKM, Marcoccl L, Tritschler HJ, Packer L, et al.: a-Lipoate in liver metabolism and disease. Free Radic Biol Med 24, 1023-1039, 1998.
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 1023-1039
-
-
Bustamante, J.1
Lodge, J.K.M.2
Marcoccl, L.3
Tritschler, H.J.4
Packer, L.5
-
25
-
-
0000197851
-
A-Lipoate: A metabolic antioxidant and potential RedOx modulator of transcription
-
Packer L, Roy S, and Sem CK: a-Lipoate: a metabolic antioxidant and potential RedOx modulator of transcription. Adv Pharmacol 38, 79-101, 1997.
-
(1997)
Adv Pharmacol
, vol.38
, pp. 79-101
-
-
Packer, L.1
Roy, S.2
Sem, C.K.3
-
26
-
-
0030570764
-
Effect of reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase, thioredoxin
-
Arner ESJ, Nordberg J, and Holmgren A: Effect of reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase, thioredoxin. Biochem Biophys Res Commun 225, 268-274, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 268-274
-
-
Arner, E.S.J.1
Nordberg, J.2
Holmgren, A.3
-
27
-
-
0035366705
-
Bile acid hydrophobicity is correlated with induction of apoptosis and/or growth arrest in HCT116 cells
-
Powell AA, LaRue JM, Batta AK, andMartinez JD: Bile acid hydrophobicity is correlated with induction of apoptosis and/or growth arrest in HCT116 cells. Biochem J 356, 481-486, 2001.
-
(2001)
Biochem J
, vol.356
, pp. 481-486
-
-
Powell, A.A.1
Larue, J.M.2
Batta, A.K.3
Martinez, J.D.4
-
28
-
-
27744466645
-
Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells
-
Lim HW, Hong S, JinW, Lim S, Kim SJ, et al.: Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells. Exp Mol Med 37, 497-506, 2005.
-
(2005)
Exp Mol Med
, vol.37
, pp. 497-506
-
-
Lim, H.W.1
Hong, S.2
Jin, W.3
Lim, S.4
Kim, S.J.5
-
29
-
-
0030813617
-
Cellular thioredoxin reductase activity is regulated by selenium
-
Berggren M, Gallegos A, Gasdaska J, and Powis G: Cellular thioredoxin reductase activity is regulated by selenium. Anticancer Res 17, 3377-3380, 1997.
-
(1997)
Anticancer Res
, vol.17
, pp. 3377-3380
-
-
Berggren, M.1
Gallegos, A.2
Gasdaska, J.3
Powis, G.4
-
30
-
-
3142718965
-
Selenium and selenomethionine levels in prostate cancer patients
-
Nyman DW, Stratton SM, Kopplin MJ, Dalkin BL, Nagle RB, et al.: Selenium and selenomethionine levels in prostate cancer patients. Cancer Detect Prev 28, 8-16, 2004.
-
(2004)
Cancer Detect Prev
, vol.28
, pp. 8-16
-
-
Nyman, D.W.1
Stratton, S.M.2
Kopplin, M.J.3
Dalkin, B.L.4
Nagle, R.B.5
-
31
-
-
0034912744
-
PTEN and myotubularin: Novel phosphoinositide phosphatases
-
Maehama T, Taylor GS, and Dixon JE: PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem 70, 247-279, 2001.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 247-279
-
-
Maehama, T.1
Taylor, G.S.2
Dixon, J.E.3
-
33
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus: Implications for PTEN stability to proteasome-mediated degradation
-
Torres J and Pulido R: The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus: implications for PTEN stability to proteasome-mediated degradation. J Biol Chem 276, 993-998, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
34
-
-
0029080674
-
Reversion of v-H-ras-transformed NIH3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes
-
Kuo ML and Yang NC: Reversion of v-H-ras-transformed NIH3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes. Biochem Biophys Res Commun 212, 767-775, 1995.
-
(1995)
Biochem Biophys Res Commun
, vol.212
, pp. 767-775
-
-
Kuo, M.L.1
Yang, N.C.2
-
35
-
-
0031819215
-
Decreased incidence of prostate cancer with selenium supplementation: Results of a double-blind cancer prevention trial
-
DOI 10.1046/j.1464-410X.1998.00630.x
-
Clark LC, Dalkin B, Krongrad A, Combs GF Jr, Turnbull BW, et al.: Decreased incidence of prostate cancer with selenium supplementation:results of a double-blind cancer prevention trial. Br J Urol 81, 730-734, 1998. (Pubitemid 28316638)
-
(1998)
British Journal of Urology
, vol.81
, Issue.5
, pp. 730-734
-
-
Clark, L.C.1
Dalkin, B.2
Krongrad, A.3
Combs Jr., G.F.4
Turnbull, B.W.5
Slate, E.H.6
Witherington, R.7
Herlong, J.H.8
Janosko, E.9
Carpenter, D.10
Borosso, C.11
Falk, S.12
Rounder, J.13
-
36
-
-
0037455838
-
Serum selenium and risk of prostate cancer in U.S. blacks and whites
-
Vogt TM, Ziegler RG, Graubard BI, Swanson CA, Greenberg RS, et al.: Serum selenium and risk of prostate cancer in U.S. blacks and whites. Int J Cancer 103, 664-670, 2003.
-
(2003)
Int J Cancer
, vol.103
, pp. 664-670
-
-
Vogt, T.M.1
Ziegler, R.G.2
Graubard, B.I.3
Swanson, C.A.4
Greenberg, R.S.5
-
37
-
-
0031794470
-
Lessons from basic research in selenium and cancer prevention
-
Ip C: Lessons from basic research in selenium and cancer prevention. J Nutr 128, 1845-1854, 1998.
-
(1998)
J Nutr
, vol.128
, pp. 1845-1854
-
-
Ip, C.1
-
38
-
-
0032126505
-
Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
-
Vliestra RJ, van Alewijk DC, Hermans KG, van Steenbrugge GJ, and Trapman J: Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res 58, 2720-2723, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 2720-2723
-
-
Vliestra, R.J.1
Van Alewijk, D.C.2
Hermans, K.G.3
Van Steenbrugge, G.J.4
Trapman, J.5
-
39
-
-
0037269847
-
Protein kinase CK2: Structure, regulation and role in cellular decisions of life and death
-
Litchfield DW: Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 369, 1-15, 2003.
-
(2003)
Biochem J
, vol.369
, pp. 1-15
-
-
Litchfield, D.W.1
-
40
-
-
0037107552
-
Protein kinase CK2: A challenge to canons
-
Pinna LA: Protein kinase CK2: a challenge to canons. J Cell Sci 115, 3873-3878, 2002.
-
(2002)
J Cell Sci
, vol.115
, pp. 3873-3878
-
-
Pinna, L.A.1
-
41
-
-
27444445782
-
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3 beta
-
Al-Khouri AM, Ma Y, Togo SH, Williams S, and Mustelin T: Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3 beta. J Biol Chem 280, 35195-35202, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 35195-35202
-
-
Al-Khouri, A.M.1
Ma, Y.2
Togo, S.H.3
Williams, S.4
Mustelin, T.5
-
42
-
-
20044377997
-
Protein kinase CK2 phosphorylates and upregulates Akt/PKB
-
Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, et al.: Protein kinase CK2 phosphorylates and upregulates Akt/PKB. Cell Death Differ 12, 668-677, 2005.
-
(2005)
Cell Death Differ
, vol.12
, pp. 668-677
-
-
Di Maira, G.1
Salvi, M.2
Arrigoni, G.3
Marin, O.4
Sarno, S.5
-
43
-
-
33744819434
-
Intracellular hydrogen peroxide production is an upstream event in apoptosis induced by down-regulation of CK2 in prostate cancer cells
-
Ahmad KA, Wang G, and Ahmed K: Intracellular hydrogen peroxide production is an upstream event in apoptosis induced by down-regulation of CK2 in prostate cancer cells. Mol Cancer Res 4, 331-338, 2006.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 331-338
-
-
Ahmad, K.A.1
Wang, G.2
Ahmed, K.3
|