-
1
-
-
33645312379
-
Circuitry of nuclear factor kappaB signaling
-
Hoffmann, A.; Baltimore, D. Circuitry of nuclear factor kappaB signaling. Immunol. Rev. 2006, 210, 171-186.
-
(2006)
Immunol. Rev.
, vol.210
, pp. 171-186
-
-
Hoffmann, A.1
Baltimore, D.2
-
2
-
-
33749043674
-
20 years of NF-kappaB
-
Chariot, A. 20 years of NF-kappaB. Biochem. Pharmacol. 2006, 7, 1051-1053.
-
(2006)
Biochem. Pharmacol.
, vol.7
, pp. 1051-1053
-
-
Chariot, A.1
-
3
-
-
0032549815
-
Cotranslational biogenesis of NF-κB p50 by the 26S proteasome
-
DOI 10.1016/S0092-8674(00)81409-9
-
Lin, L.; DeMartino, G. N.; Greene, W. C. Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome. Cell 1998, 92, 819-828. (Pubitemid 28155320)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 819-828
-
-
Lin, L.1
Demartino, G.N.2
Greene, W.C.3
-
4
-
-
33845768987
-
Integrating cell-signalling pathways with NF-κB and IKK function
-
DOI 10.1038/nrm2083, PII NRM2083
-
Perkins, N. D. Integrating cell-signalling pathways with NFkappaB and IKK function. Nat. Rev. Mol. Cell Biol. 2007, 8, 49-62. (Pubitemid 46012014)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.1
, pp. 49-62
-
-
Perkins, N.D.1
-
5
-
-
33646531810
-
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling
-
Massoumi, R.; Chmielarska, K.; Hennecke, K.; Pfeifer, A.; Fassler, R. Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell 2006, 125, 665-677.
-
(2006)
Cell
, vol.125
, pp. 665-677
-
-
Massoumi, R.1
Chmielarska, K.2
Hennecke, K.3
Pfeifer, A.4
Fassler, R.5
-
6
-
-
0027175501
-
The bcl-3 proto-oncogene encodes a nuclear IκB-like molecule that preferentially interacts with NF-κB p50 and p52 in a phosphorylation- Dependent manner
-
Nolan, G. P.; Fujita, T.; Bhatia, K.; Huppi, C.; Liou, H. C.; Scott, M. L.; Baltimore, D. The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner. Mol. Cell Biol. 1993, 13, 3557-3566. (Pubitemid 23157293)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.6
, pp. 3557-3566
-
-
Nolan, G.P.1
Fujita, T.2
Bhatia, K.3
Huppi, C.4
Liou, H.-C.5
Scott, M.L.6
Baltimore, D.7
-
7
-
-
0027332498
-
The IkappaB proteins: Multifunctional regulators of Rel/NF-kappaB transcription factors
-
Beg, A. A.; Baldwin, A. S., Jr. The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors. Genes Dev. 1993, 7, 2064-2070. (Pubitemid 2010879)
-
(1993)
Genes and Development
, vol.7
, Issue.11
, pp. 2064-2070
-
-
Beg, A.A.1
Baldwin Jnr, A.S.2
-
8
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
Baldwin, A. S. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J. Clin. Invest. 2001, 107, 241-246. (Pubitemid 32157954)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.3
, pp. 241-246
-
-
Baldwin, A.S.1
-
9
-
-
0037207474
-
βTrCP-mediated proteolysis of NF-κB1 p105 requires phosphorylation of p105 serines 927 and 932
-
DOI 10.1128/MCB.23.1.402-413.2003
-
Lang, V.; Janzen, J.; Fischer, G. Z.; Soneji, Y.; Beinke, S.; Salmeron, A.; Allen, H.; Hay, R. T.; Ben-Neriah, Y.; Ley, S. C. betaTrCP- mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932. Mol. Cell Biol. 2003, 23, 402-413. (Pubitemid 36008530)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.1
, pp. 402-413
-
-
Lang, V.1
Janzen, J.2
Fischer, G.Z.3
Soneji, Y.4
Beinke, S.5
Salmeron, A.6
Allen, H.7
Hay, R.T.8
Ben-Neriah, Y.9
Ley, S.C.10
-
10
-
-
15444363021
-
337 by the protein kinase a catalytic subunit
-
DOI 10.1074/jbc.M412180200
-
Guan, H.; Hou, S.; Ricciardi, R. P. DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit. J. Biol. Chem. 2005, 280, 9957-9962. (Pubitemid 40395844)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 9957-9962
-
-
Guan, H.1
Hou, S.2
Ricciardi, R.P.3
-
11
-
-
0036203419
-
The phosphorylation status of nuclear NF-κB determines its association with CBP/p300 or HDAC-1
-
DOI 10.1016/S1097-2765(02)00477-X
-
Zhong, H.; May, M. J.; Jimi, E.; Ghosh, S. The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 2002, 9, 625-636. (Pubitemid 34273792)
-
(2002)
Molecular Cell
, vol.9
, Issue.3
, pp. 625-636
-
-
Zhong, H.1
May, M.J.2
Jimi, E.3
Ghosh, S.4
-
12
-
-
0025999203
-
Cytoplasmic retention, DNA binding and processing of the NF-κ B p50 precursor are controlled by a small region in its C-terminus
-
Blank, V.; Kourilsky, P.; Israel, A. Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus. EMBO J. 1991, 10, 4159-4167. (Pubitemid 21905448)
-
(1991)
EMBO Journal
, vol.10
, Issue.13
, pp. 4159-4167
-
-
Blank, V.1
Kourilsky, P.2
Israel, A.3
-
13
-
-
0242664264
-
Phosphorylation of Serine 337 of NF-κB p50 is Critical for DNA Binding
-
DOI 10.1074/jbc.M307971200
-
Hou, S.; Guan, H.; Ricciardi, R. P. Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding. J. Biol. Chem. 2003, 278, 45994-45998. (Pubitemid 37432747)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45994-45998
-
-
Hou, S.1
Guan, H.2
Ricciardi, R.P.3
-
14
-
-
33751221923
-
IKKβ programs to turn on the GADD45α-MKK4-JNK apoptotic cascade specifically via p50 NF-κB in arsenite response
-
DOI 10.1083/jcb.200602149
-
Song, L.; Li, J.; Zhang, D.; Liu, Z. G.; Ye, J.; Zhan, Q.; Shen, H. M.; Whiteman, M.; Huang, C. IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response. J. Cell Biol. 2006, 175, 607-617. (Pubitemid 44790614)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.4
, pp. 607-617
-
-
Song, L.1
Li, J.2
Zhang, D.3
Liu, Z.-G.4
Ye, J.5
Zhan, Q.6
Shen, H.-M.7
Whiteman, M.8
Huang, C.9
-
15
-
-
0032514967
-
A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
-
Takekawa, M.; Saito, H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell 1998, 95, 521-530. (Pubitemid 28533308)
-
(1998)
Cell
, vol.95
, Issue.4
, pp. 521-530
-
-
Takekawa, M.1
Saito, H.2
-
16
-
-
0035914346
-
Oligomerization of Human Gadd45a Protein
-
DOI 10.1074/jbc.M105115200
-
Kovalsky, O.; Lung, F. D.; Roller, P. P.; Fornace, A. J., Jr. Oligomerization of human Gadd45a protein. J. Biol. Chem. 2002, 276, 39330-39339. (Pubitemid 37371310)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.42
, pp. 39330-39339
-
-
Kovalsky, O.1
Lung, F.-D.T.2
Roller, P.P.3
Fornace Jr., A.J.4
-
17
-
-
0036275374
-
Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding
-
DOI 10.1128/MCB.22.13.4544-4555.2002
-
Mita, H.; Tsutsui, J.; Takekawa, M.; Witten, E. A.; Saito, H. Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding. Mol. Cell Biol. 2002, 22, 4544-4555. (Pubitemid 34620392)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.13
, pp. 4544-4555
-
-
Mita, H.1
Tsutsui, J.2
Takekawa, M.3
Witten, E.A.4
Saito, H.5
-
18
-
-
0032473405
-
B lymphocytes differentially use the Rel and nuclear factor κB1 (NF- κB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells
-
DOI 10.1084/jem.187.5.663
-
Grumont, R. J.; Rourke, I. J.; O'Reilly, L. A.; Strasser, A.; Miyake, K.; Sha, W.; Gerondakis, S. B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J. Exp. Med. 1998, 187, 663-674. (Pubitemid 28115182)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.5
, pp. 663-674
-
-
Grumont, R.J.1
Rourke, I.J.2
O'Reilly, L.A.3
Strasser, A.4
Miyake, K.5
Sha, W.6
Gerondakis, S.7
-
19
-
-
0030934694
-
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway
-
DOI 10.1074/jbc.272.13.8288
-
Gerwins, P.; Blank, J. L.; Johnson, G. L. Cloning of a novel mitogen- activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway. J. Biol. Chem. 1997, 272, 8288-8295. (Pubitemid 27147785)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.13
, pp. 8288-8295
-
-
Gerwins, P.1
Blank, J.L.2
Johnson, G.L.3
-
20
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c- Mediated death pathway
-
DOI 10.1126/science.288.5467.870
-
Tournier, C.; Hess, P.; Yang, D. D.; Xu, J.; Turner, T. K.; Nimnual, A.; Bar-Sagi, D.; Jones, S. N.; Flavell, R. A.; Davis, R. J. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000, 288, 870-874. (Pubitemid 30257738)
-
(2000)
Science
, vol.288
, Issue.5467
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
21
-
-
3042630489
-
Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells
-
DOI 10.1038/sj.onc.1207598
-
Yin, F.; Bruemmer, D.; Blaschke, F.; Hsueh, W. A.; Law, R. E.; Herle, A. J. Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells. Oncogene 2004, 23, 4614-4623. (Pubitemid 38850409)
-
(2004)
Oncogene
, vol.23
, Issue.26
, pp. 4614-4623
-
-
Yin, F.1
Bruemmer, D.2
Blaschke, F.3
Hsueh, W.A.4
Law, R.E.5
Van Herle, A.J.6
-
22
-
-
33845946480
-
Coordination of JNK1 and JNK2 is critical for GADD45α induction and its mediated cell apoptosis in arsenite responses
-
DOI 10.1074/jbc.M602821200
-
Zhang, D.; Song, L.; Li, J.; Wu, K.; Huang, C. Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses. J. Biol. Chem. 2006, 281, 34113-34123. (Pubitemid 46036620)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.45
, pp. 34113-34123
-
-
Zhang, D.1
Song, L.2
Li, J.3
Wu, K.4
Huang, C.5
-
23
-
-
0032737937
-
The NF-kappaB/Rel family of transcription factors in oncogenic transformation and apoptosis
-
de Martin, R.; Schmid, J. A.; Hofer-Warbinek, R. The NF-kappaB/Rel family of transcription factors in oncogenic transformation and apoptosis. Mutat. Res. 1999, 437, 231-243.
-
(1999)
Mutat. Res.
, vol.437
, pp. 231-243
-
-
De Martin, R.1
Schmid, J.A.2
Hofer-Warbinek, R.3
-
24
-
-
0033596127
-
Control of apoptosis by Rel/NF-kappaB transcription factors
-
Barkett, M.; Gilmore, T. D. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 1999, 18, 6910-6924.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
25
-
-
0036594361
-
Expression of NF-kappa B in human bladder cancer and its clinical significance
-
Xie, D. H.; Tang, X. D.; Xia, S. J.; Tan, J. M.; Wang, X. H.; Cai, Y. Expression of NF-kappa B in human bladder cancer and its clinical significance. Ai Zheng 2002, 21, 663-667.
-
(2002)
Ai Zheng
, vol.21
, pp. 663-667
-
-
Xie, D.H.1
Tang, X.D.2
Xia, S.J.3
Tan, J.M.4
Wang, X.H.5
Cai, Y.6
-
26
-
-
0033201450
-
NF-κB activation is required for human endothelial survival during exposure to tumor necrosis factor-α but not to interleukin-1β or lipopolysaccharide
-
Zen, K.; Karsan, A.; Stempien-Otero, A.; Yee, E.; Tupper, J.; Li, X.; Eunson, T.; Kay, M. A.; Wilson, C. B.; Winn, R. K.; Harlan, J. M. NF-kappaB activation is required for human endothelial survival during exposure to tumor necrosis factor-alpha but not to interleukin-1beta or lipopolysaccharide. J. Biol. Chem. 1999, 274, 28808-28815. (Pubitemid 129504760)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.40
, pp. 28808-28815
-
-
Zen, Z.1
Karsan, A.2
Stempien-Otero, A.3
Yee, E.4
Tupper, J.5
Li, X.6
Eunson, T.7
Kay, M.A.8
Wilson, C.B.9
Winn, R.K.10
Harlan, J.M.11
-
27
-
-
0033072728
-
An essential role for nuclear factor kappa B in preventing TNF-alpha-induced cell death in prostate cancer cells
-
Sumitomo, M.; Tachibana, M.; Nakashima, J.; Murai, M.; Miyajima, A.; Kimura, F.; Hayakawa, M.; Nakamura, H. An essential role for nuclear factor kappa B in preventing TNF-alpha-induced cell death in prostate cancer cells. J. Urol. 1999, 161, 674-679.
-
(1999)
J. Urol.
, vol.161
, pp. 674-679
-
-
Sumitomo, M.1
Tachibana, M.2
Nakashima, J.3
Murai, M.4
Miyajima, A.5
Kimura, F.6
Hayakawa, M.7
Nakamura, H.8
-
28
-
-
0033134106
-
Salicylates inhibit NF-κB activation and enhance TNF-α-induced apoptosis in human pancreatic cancer cells
-
DOI 10.1006/jsre.1998.5560
-
McDade, T. P.; Perugini, R. A.; Vittimberga, F. J., Jr.; Carrigan, R. C.; Callery, M. P. Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells. J. Surg. Res. 1999, 83, 56-61. (Pubitemid 29394107)
-
(1999)
Journal of Surgical Research
, vol.83
, Issue.1
, pp. 56-61
-
-
McDade, T.P.1
Perugini, R.A.2
Vittimberga Jr., F.J.3
Carrigan, R.C.4
Callery, M.P.5
-
29
-
-
0034743275
-
Effects of NF-κB1 (p50) targeted gene disruption on ionizing radiation-induced NF-κB activation and TNFα, IL-1α, IL-1β and IL-6 mRNA expression in vivo
-
DOI 10.1080/09553000110050047
-
Zhou, D.; Yu, T.; Chen, G.; Brown, S. A.; Yu, Z.; Mattson, M. P.; Thompson, J. S. Effects of NF-kappaB1 (p50) targeted gene disruption on ionizing radiation-induced NF-kappaB activation and TNFalpha, IL-1alpha, IL-1beta and IL-6 mRNA expression in vivo. Int. J. Radiat. Biol. 2001, 77, 763-772. (Pubitemid 32625544)
-
(2001)
International Journal of Radiation Biology
, vol.77
, Issue.7
, pp. 763-772
-
-
Zhou, D.1
Yu, T.2
Chen, G.3
Brown, S.A.4
Yu, Z.5
Mattson, M.P.6
Thompson, J.S.7
-
30
-
-
52049093879
-
Inhibition of the promotion of hepatocarcinogenesis by 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappaB in mice
-
Glauert, H. P.; Tharappel, J. C.; Banerjee, S.; Chan, L. S.; Kania-Korwel, I.; Lehmler, H. J.; Lee, E. Y.; Robertson, L. W.; Spear, B. T. Inhibition of the promotion of hepatocarcinogenesis by 2,2′,4,4′,5, 5′-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappaB in mice. Toxicol. Appl. Pharmacol. 2008, 232, 302-308.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.232
, pp. 302-308
-
-
Glauert, H.P.1
Tharappel, J.C.2
Banerjee, S.3
Chan, L.S.4
Kania-Korwel, I.5
Lehmler, H.J.6
Lee, E.Y.7
Robertson, L.W.8
Spear, B.T.9
-
31
-
-
0034705110
-
NF-κB inhibition causes spontaneous apoptosis in Epstein-Barr virus- Transformed lymphoblastoid cells
-
DOI 10.1073/pnas.100119497
-
Cahir-McFarland, E. D.; Davidson, D. M.; Schauer, S. L.; Duong, J.; Kieff, E. NF-kappa B inhibition causes spontaneous apoptosis in Epstein-Barr virus-transformed lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 2000, 97, 6055-6060. (Pubitemid 30367522)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.11
, pp. 6055-6060
-
-
Cahir-McFarland, E.D.1
Davidson, D.M.2
Schauer, S.L.3
Duong, J.4
Kieff, E.5
-
32
-
-
33745167654
-
The role of NF-κB-1 and NF-κB-2-mediated resistance to apoptosis in lymphomas
-
DOI 10.1073/pnas.0507809103
-
Bernal-Mizrachi, L.; Lovly, C. M.; Ratner, L. The role of NF- {kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas. Proc. Natl. Acad. Sci. USA 2006, 103, 9220-9225. (Pubitemid 43902559)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.24
, pp. 9220-9225
-
-
Bernal-Mizrachi, L.1
Lovly, C.M.2
Ratner, L.3
-
33
-
-
37049004740
-
Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas
-
DOI 10.1159/000111116
-
O'Neil, B. H.; Buzkova, P.; Farrah, H.; Kashatus, D.; Sanoff, H.; Goldberg, R. M.; Baldwin, A. S.; Funkhouser, W. K. Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas. Oncology 2007, 72, 97-104. (Pubitemid 350249136)
-
(2007)
Oncology
, vol.72
, Issue.1-2
, pp. 97-104
-
-
O'Neil, B.H.1
Buzkova, P.2
Farrah, H.3
Kashatus, D.4
Sanoff, H.5
Goldberg, R.M.6
Baldwin, A.S.7
Funkhouser, W.K.8
-
34
-
-
0023879839
-
Recombinant human interleukin 5 is a selective activator of human eosinophil function
-
Lopez, A. F.; Sanderson, C. J.; Gamble, J. R.; Campbell, H. D.; Young, I. G.; Vadas, M. A. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 1988, 167, 219-224. (Pubitemid 18093705)
-
(1988)
Journal of Experimental Medicine
, vol.167
, Issue.1
, pp. 219-224
-
-
Lopez, A.F.1
Sanderson, C.J.2
Gamble, J.R.3
Campbell, H.D.4
Young, I.G.5
Vadas, M.A.6
-
35
-
-
0032476742
-
Essential role of nuclear factor κB in the induction of eosinophilia in allergic airway inflammation
-
DOI 10.1084/jem.188.9.1739
-
Yang, L.; Cohn, L.; Zhang, D. H.; Homer, R.; Ray, A.; Ray, P. Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation. J. Exp. Med. 1998, 188, 1739-1750. (Pubitemid 28516118)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.9
, pp. 1739-1750
-
-
Yang, L.1
Cohn, L.2
Zhang, D.-H.3
Homer, R.4
Ray, A.5
Ray, P.6
-
36
-
-
0023875104
-
Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors
-
Yamaguchi, Y.; Suda, T.; Suda, J.; Eguchi, M.; Miura, Y.; Harada, N.; Tominaga, A.; Takatsu, K. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 1988, 167, 43-56. (Pubitemid 18093692)
-
(1988)
Journal of Experimental Medicine
, vol.167
, Issue.1
, pp. 43-56
-
-
Yamaguchi, Y.1
Suda, T.2
Suda, J.3
Eguchi, M.4
Miura, Y.5
Harada, N.6
Tominaga, A.7
Takatsu, K.8
-
37
-
-
0030048332
-
B cells from p50/NF-κB knockout mice have selective defects in proliferation, differentiation, germ-line C(H) transcription, and Ig class switching
-
Snapper, C. M.; Zelazowski, P.; Rosas, F. R.; Kehry, M. R.; Tian, M.; Baltimore, D.; Sha, W. C. B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching. J. Immunol. 1996, 156, 183-191. (Pubitemid 26006962)
-
(1996)
Journal of Immunology
, vol.156
, Issue.1
, pp. 183-191
-
-
Snapper, C.M.1
Zelazowski, P.2
Rosas, F.R.3
Kehry, M.R.4
Tian, M.5
Baltimore, D.6
Sha, W.C.7
-
38
-
-
33745308424
-
-) bone marrow cells
-
Pelletier, M.; Girard, D. Differential effects of IL-15 and IL-21 in myeloid (CD11b+) and lymphoid (CD11b-) bone marrow cells. J. Immunol. 2006, 177, 100-108. (Pubitemid 43939121)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 100-108
-
-
Pelletier, M.1
Girard, D.2
-
39
-
-
0035081675
-
Normal liver regeneration in p50/nuclear factor κB1 knockout mice
-
DOI 10.1053/jhep.2001.23192
-
DeAngelis, R. A.; Kovalovich, K.; Cressman, D. E.; Taub, R. Normal liver regeneration in p50/nuclear factor kappaB1 knockout mice. Hepatology 2001, 33, 915-924. (Pubitemid 32246641)
-
(2001)
Hepatology
, vol.33
, Issue.4
, pp. 915-924
-
-
Deangelis, R.A.1
Kovalovich, K.2
Cressman, D.E.3
Taub, R.4
-
40
-
-
21044435329
-
Dendritic cell-intrinsic expression of NF-κB1 is required to promote optimal Th2 cell differentiation
-
Artis, D.; Kane, C. M.; Fiore, J.; Zaph, C.; Shapira, S.; Joyce, K.; Macdonald, A.; Hunter, C.; Scott, P.; Pearce, E. J. Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation. J. Immunol. 2005, 174, 7154-7159. (Pubitemid 40705682)
-
(2005)
Journal of Immunology
, vol.174
, Issue.11
, pp. 7154-7159
-
-
Artis, D.1
Kane, C.M.2
Fiore, J.3
Zaph, C.4
Shapira, S.5
Joyce, K.6
MacDonald, A.7
Hunter, C.8
Scott, P.9
Pearce, E.J.10
-
41
-
-
33746676886
-
Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor κB1 and mitogen-activated protein kinase pathways
-
DOI 10.1111/j.1742-4658.2006.05384.x
-
Schafer, R.; Hartig, R.; Sedehizade, F.; Welte, T.; Reiser, G. Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kappaB1 and mitogen-activated protein kinase pathways. FEBS J. 2006, 273, 3756-3767. (Pubitemid 44166656)
-
(2006)
FEBS Journal
, vol.273
, Issue.16
, pp. 3756-3767
-
-
Schafer, R.1
Hartig, R.2
Sedehizade, F.3
Welte, T.4
Reiser, G.5
-
42
-
-
0032588186
-
NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1
-
Guttridge, D. C.; Albanese, C.; Reuther, J. Y.; Pestell, R. G.; Baldwin, A. S., Jr. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol. Cell Biol. 1999, 19, 5785-5799. (Pubitemid 29339933)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.8
, pp. 5785-5799
-
-
Guttridge, D.C.1
Albanese, C.2
Reuther, J.Y.3
Pestell, R.G.4
Baldwin Jr., A.S.5
-
43
-
-
0032588170
-
1-to-S-phase transition
-
Hinz, M.; Krappmann, D.; Eichten, A.; Heder, A.; Scheidereit, C.; Strauss, M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol. Cell Biol.1999, 19, 2690-2698. (Pubitemid 29144513)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.4
, pp. 2690-2698
-
-
Hinz, M.1
Krappmann, D.2
Eichten, A.3
Heder, A.4
Scheidereit, C.5
Strauss, M.6
-
44
-
-
22144449607
-
Constitutive activation of PI3K-Akt and NF-κB during prostate cancer progression in autochthonous transgenic mouse model
-
DOI 10.1002/pros.20217
-
Shukla, S.; Maclennan, G. T.; Marengo, S. R.; Resnick, M. I.; Gupta, S. Constitutive activation of PI3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Prostate 2005, 64, 224-239. (Pubitemid 40980864)
-
(2005)
Prostate
, vol.64
, Issue.3
, pp. 224-239
-
-
Shukla, S.1
MacLennan, G.T.2
Marengo, S.R.3
Resnick, M.I.4
Gupta, S.5
-
45
-
-
4444297823
-
Effect of 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-κB
-
DOI 10.1093/toxsci/kfh193
-
Lu, Z.; Lee, E. Y.; Robertson, L. W.; Glauert, H. P.; Spear, B. T. Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-kappaB. Toxicol. Sci. 2004, 81, 35-42. (Pubitemid 39199861)
-
(2004)
Toxicological Sciences
, vol.81
, Issue.1
, pp. 35-42
-
-
Lu, Z.1
Lee, E.Y.2
Robertson, L.W.3
Glauert, H.P.4
Spear, B.T.5
-
46
-
-
33749444114
-
Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on older male areca (betel) chewers
-
DOI 10.1016/j.canlet.2005.11.019, PII S0304383505010189
-
Lin, S. C.; Liu, C. J.; Yeh, W. I.; Lui, M. T.; Chang, K. W.; Chang, C. S. Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on older male areca (betel) chewers. Cancer Lett. 2006, 243, 47-54. (Pubitemid 44508646)
-
(2006)
Cancer Letters
, vol.243
, Issue.1
, pp. 47-54
-
-
Lin, S.-C.1
Liu, C.-J.2
Yeh, W.-I.3
Lui, M.-T.4
Chang, K.-W.5
Chang, C.-S.6
-
47
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill, F.; Mantovani, A. Inflammation and cancer: back to Virchow? Lancet 2001, 357, 539-545.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
48
-
-
23044498269
-
Inactivation of nuclear factor κB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells
-
DOI 10.1158/0008-5472.CAN-04-4604
-
Li, Y.; Ahmed, F.; Ali, S.; Philip, P. A.; Kucuk, O.; Sarkar, F. H. Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Res. 2005, 65, 6934-6942. (Pubitemid 41060733)
-
(2005)
Cancer Research
, vol.65
, Issue.15
, pp. 6934-6942
-
-
Li, Y.1
Ahmed, F.2
Ali, S.3
Philip, P.A.4
Kucuk, O.5
Sarkar, F.H.6
-
49
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M.; Werb, Z. Inflammation and cancer. Nature 2002, 420, 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
50
-
-
35848960997
-
Inflammation and lung carcinogenesis: Applying findings in prevention and treatment
-
DOI 10.1586/14737140.7.10.1405
-
Peebles, K. A.; Lee, J. M.; Mao, J. T.; Hazra, S.; Reckamp, K. L.; Krysan, K.; Dohadwala, M.; Heinrich, E. L.; Walser, T. C.; Cui, X.; Baratelli, F. E.; Garon, E.; Sharma, S.; Dubinett, S. M. Inflammation and lung carcinogenesis: applying findings in prevention and treatment. Expert Rev. Anticancer Ther. 2007, 7, 1405-1421. (Pubitemid 351826907)
-
(2007)
Expert Review of Anticancer Therapy
, vol.7
, Issue.10
, pp. 1405-1421
-
-
Peebles, K.A.1
Lee, J.M.2
Mao, J.T.3
Hazra, S.4
Reckamp, K.L.5
Krysan, K.6
Dohadwala, M.7
Heinrich, E.L.8
Walser, T.C.9
Cui, X.10
Baratelli, F.E.11
Garon, E.12
Sharma, S.13
Dubinett, S.M.14
-
51
-
-
0032489828
-
Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-κB1) but expressing p50
-
DOI 10.1084/jem.187.7.985
-
Ishikawa, H.; Claudio, E.; Dambach, D.; Raventos-Suarez, C.; Ryan, C.; Bravo, R. Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50. J. Exp. Med. 1998, 187, 985-996. (Pubitemid 28176399)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.7
, pp. 985-996
-
-
Ishikawa, H.1
Claudio, E.2
Dambach, D.3
Raventos-Suarez, C.4
Ryan, C.5
Bravo, R.6
-
52
-
-
0035991445
-
Gene deletion of NF-κB p50 does not alter the hepatic inflammatory response to ischemia/reperfusion
-
DOI 10.1016/S0168-8278(02)00068-5, PII S0168827802000685
-
Kato, A.; Edwards, M. J.; Lentsch, A. B. Gene deletion of NF-kappa B p50 does not alter the hepatic inflammatory response to ischemia/reperfusion. J. Hepatol. 2002, 37, 48-55. (Pubitemid 34713054)
-
(2002)
Journal of Hepatology
, vol.37
, Issue.1
, pp. 48-55
-
-
Kato, A.1
Edwards, M.J.2
Lentsch, A.B.3
-
53
-
-
9644268197
-
BCL-3 and NF-κB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages
-
DOI 10.1074/jbc.M404246200
-
Wessells, J.; Baer, M.; Young, H. A.; Claudio, E.; Brown, K.; Siebenlist, U.; Johnson, P. F. BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages. J. Biol. Chem. 2004, 279, 49995-50003. (Pubitemid 39577809)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.48
, pp. 49995-50003
-
-
Wessells, J.1
Baer, M.2
Young, H.A.3
Claudio, E.4
Brown, K.5
Siebenlist, U.6
Johnson, P.F.7
-
54
-
-
33748756806
-
NF-κB1 (p50) homodimers differentially regulate pro- And anti-inflammatory cytokines in macrophages
-
DOI 10.1074/jbc.M602222200
-
Cao, S.; Zhang, X.; Edwards, J. P.; Mosser, D. M. NF-kappaB1 (p50) homodimers differentially regulate pro- and antiinflammatory cytokines in macrophages. J. Biol. Chem. 2006, 281, 26041-26050. (Pubitemid 44401810)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.36
, pp. 26041-26050
-
-
Cao, S.1
Zhang, X.2
Edwards, J.P.3
Mosser, D.M.4
-
55
-
-
14644394327
-
Nuclear factor-κB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury
-
Oakley, F.; Mann, J.; Nailard, S.; Smart, D. E.; Mungalsingh, N.; Constandinou, C.; Ali, S.; Wilson, S. J.; Millward-Sadler, H.; Iredale, J. P.; Mann, D. A. Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury. Am. J. Pathol. 2005, 166, 695-708. (Pubitemid 40315627)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.3
, pp. 695-708
-
-
Oakley, F.1
Mann, J.2
Nailard, S.3
Smart, D.E.4
Mungalsingh, N.5
Constandinou, C.6
Ali, S.7
Wilson, S.J.8
Millward-Sadler, H.9
Iredale, J.P.10
Mann, D.A.11
-
56
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
-
Greten, F. R.; Eckmann, L.; Greten, T. F.; Park, J. M.; Li, Z. W.; Egan, L. J.; Kagnoff, M. F.; Karin, M. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004, 118, 285-296. (Pubitemid 39061110)
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.-W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
57
-
-
41049113475
-
NF-kappa B genes have a major role in inflammatory breast cancer
-
Lerebours, F.; Vacher, S.; Andrieu, C.; Espie, M.; Marty, M.; Lidereau, R.; Bieche, I. NF-kappa B genes have a major role in inflammatory breast cancer. BMC Cancer 2008, 8, 41.
-
(2008)
BMC Cancer
, vol.8
, pp. 41
-
-
Lerebours, F.1
Vacher, S.2
Andrieu, C.3
Espie, M.4
Marty, M.5
Lidereau, R.6
Bieche, I.7
-
58
-
-
4644324186
-
NF-κB functions as a tumour promoter in inflammation-associated cancer
-
DOI 10.1038/nature02924
-
Pikarsky, E.; Porat, R. M.; Stein, I.; Abramovitch, R.; Amit, S.; Kasem, S.; Gutkovich-Pyest, E.; Urieli-Shoval, S.; Galun, E.; Ben-Neriah, Y. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004, 431, 461-466. (Pubitemid 39329586)
-
(2004)
Nature
, vol.431
, Issue.7007
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
Gutkovich-Pyest, E.7
Uriell-Shoval, S.8
Galun, E.9
Ben-Neriah, Y.10
-
59
-
-
33750372570
-
Anti-inflammatory effects of a novel peptide designed to bind with NF-κB p50 subunit
-
DOI 10.1111/j.1745-7254.2006.00442.x
-
Wang, Z. P.; Cai, S. X.; Liu, D. B.; Xu, X.; Liang, H. P. Antiinflammatory effects of a novel peptide designed to bind with NFkappaB p50 subunit. Acta. Pharmacol. Sin. 2006, 27, 1474-1478. (Pubitemid 44630316)
-
(2006)
Acta Pharmacologica Sinica
, vol.27
, Issue.11
, pp. 1474-1478
-
-
Wang, Z.-P.1
Cai, S.-X.2
Liu, D.-B.3
Xu, X.4
Liang, H.-P.5
-
60
-
-
0026689558
-
The origin and function of tumor-associated macrophages
-
Mantovani, A.; Bottazzi, B.; Colotta, F.; Sozzani, S.; Ruco, L. The origin and function of tumor-associated macrophages. Immunol. Today 1992, 13, 265-270.
-
(1992)
Immunol. Today
, vol.13
, pp. 265-270
-
-
Mantovani, A.1
Bottazzi, B.2
Colotta, F.3
Sozzani, S.4
Ruco, L.5
-
61
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
-
Mantovani, A.; Sozzani, S.; Locati, M.; Allavena, P.; Sica, A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 2002, 23, 549-555. (Pubitemid 35223554)
-
(2002)
Trends in Immunology
, vol.23
, Issue.11
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
62
-
-
0034650833
-
Autocrine production of IL-10 mediates defective IL-12 production and NF-κB activation in tumor-associated macrophages
-
Sica, A.; Saccani, A.; Bottazzi, B.; Polentarutti, N.; Vecchi, A.; van Damme, J.; Mantovani, A. Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J. Immunol. 2000, 164, 762-767. (Pubitemid 30043699)
-
(2000)
Journal of Immunology
, vol.164
, Issue.2
, pp. 762-767
-
-
Sica, A.1
Saccani, A.2
Bottazzi, B.3
Polentarutti, N.4
Vecchi, A.5
Van Damme, J.6
Mantovani, A.7
-
63
-
-
33845752914
-
P50 nuclear factor-κB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
-
DOI 10.1158/0008-5472.CAN-06-1867
-
Saccani, A.; Schioppa, T.; Porta, C.; Biswas, S. K.; Nebuloni, M.; Vago, L.; Bottazzi, B.; Colombo, M. P.; Mantovani, A.; Sica, A. p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res. 2006, 66, 11432-11440. (Pubitemid 46009975)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11432-11440
-
-
Saccani, A.1
Schioppa, T.2
Porta, C.3
Biswas, S.K.4
Nebuloni, M.5
Vago, L.6
Bottazzi, B.7
Colombo, M.P.8
Mantovani, A.9
Sica, A.10
-
64
-
-
23244466456
-
Areca (betel) nut extract activates mitogen-activated protein kinases and NF-κB in oral keratinocytes
-
DOI 10.1002/ijc.21104
-
Lin, S. C.; Lu, S. Y.; Lee, S. Y.; Lin, C. Y.; Chen, C. H.; Chang, K. W. Areca (betel) nut extract activates mitogen-activated protein kinases and NF-kappaB in oral keratinocytes. Int. J. Cancer 2005, 116, 526-535. (Pubitemid 41099188)
-
(2005)
International Journal of Cancer
, vol.116
, Issue.4
, pp. 526-535
-
-
Lin, S.-C.1
Lu, S.-Y.2
Lee, S.-Y.3
Lin, C.-Y.4
Chen, C.-H.5
Chang, K.-W.6
-
65
-
-
0035976997
-
NF-κB1 (p50) Homodimers Contribute to Transcription of the bcl-2 Oncogene
-
DOI 10.1074/jbc.M108294200
-
Kurland, J. F.; Kodym, R.; Story, M. D.; Spurgers, K. B.; McDonnell, T. J.; Meyn, R. E. NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. J. Biol. Chem. 2001, 276, 45380-45386. (Pubitemid 37391335)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.48
, pp. 45380-45386
-
-
Kurland, J.F.1
Kodym, R.2
Story, M.D.3
Spurgers, K.B.4
McDonnell, T.J.5
Meyn, R.E.6
-
66
-
-
0346365370
-
Activation of Nuclear Factor-κB p50 Homodimer/Bcl-3 Complexes in Nasopharyngeal Carcinoma
-
Thornburg, N. J.; Pathmanathan, R.; Raab-Traub, N. Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinoma. Cancer Res. 2003, 63, 8293-8301. (Pubitemid 37549481)
-
(2003)
Cancer Research
, vol.63
, Issue.23
, pp. 8293-8301
-
-
Thornburg, N.J.1
Pathmanathan, R.2
Raab-Traub, N.3
-
67
-
-
0029114985
-
Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma
-
Mukhopadhyay, T.; Roth, J. A.; Maxwell, S. A. Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma. Oncogene 1995, 11, 999-1003.
-
(1995)
Oncogene
, vol.11
, pp. 999-1003
-
-
Mukhopadhyay, T.1
Roth, J.A.2
Maxwell, S.A.3
-
68
-
-
0033539885
-
Increased expression of p50-NF-κB and constitutive activation of NF-κB transcription factors during mouse skin carcinogenesis
-
Budunova, I. V.; Perez, P.; Vaden, V. R.; Spiegelman, V. S.; Slaga, T. J.; Jorcano, J. L. Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis. Oncogene 1999, 18, 7423-7431. (Pubitemid 30035043)
-
(1999)
Oncogene
, vol.18
, Issue.52
, pp. 7423-7431
-
-
Budunova, I.V.1
Perez, P.2
Vaden, V.R.3
Spiegelman, V.S.4
Slaga, T.J.5
Jorcano, J.L.6
|