The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury

BMC Infectious Diseases

Volumn 9, Issue , 2009, Pages

  Choi, Won Il ^a,b,c   Young, Kun Young ^a,b   Wook, Jeong Wook ^d   Beagle, John ^c   Quinn, Deborah A ^c   Hales, Charles A ^c  

^a Keimyung University School of Medicine   (South Korea)

^b Keimyung University   (South Korea)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Seoul National University Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMRINONE; CREATININE; CYCLIC AMP; ENDOTOXIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; PHOSPHODIESTERASE 3A; PHOSPHODIESTERASE 3B; PHOSPHODIESTERASE III; UNCLASSIFIED DRUG; UREA; NOS2 PROTEIN, RAT; PDE3A PROTEIN, RAT; PDE3B PROTEIN, RAT;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY DISTAL TUBULE; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; UPREGULATION; UREA NITROGEN BLOOD LEVEL; ANIMAL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; KIDNEY; METABOLISM; PATHOLOGY; ULTRASTRUCTURE;

AMRINONE; ANIMALS; BLOOD UREA NITROGEN; CREATININE; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KIDNEY; KIDNEY TUBULES, DISTAL; KIDNEY TUBULES, PROXIMAL; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE SYNTHASE TYPE II; RATS;

EID: 67649349935     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-9-80     Document Type: Article

References (47)

1. Ympa YP Sakr Y Reinhart K Vincent JL Has mortality from acute renal failure decreased? A systematic review of the literature Am J Med 2005, 118(8):827-832. 10.1016/j.amjmed.2005.01.069 16084171
2. Rangel-Frausto MS Pittet D Costigan M Hwang T Davis CS Wenzel RP The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study JAMA 1995, 273(2):117-123. 10.1001/jama.273.2.117 7799491
3. Schrier RW Wang W Acute renal failure and sepsis N Engl J Med 2004, 351(2):159-169. 10.1056/NEJMra032401 15247356
4. Lee JH Del Sorbo L Uhlig S Porro GA Whitehead T Voglis S Liu M Slutsky AS Zhang H Intercellular adhesion molecule-1 mediates cellular cross-talk between parenchymal and immune cells after lipopolysaccharide neutralization J Immunol 2004, 172(1):608-616. 14688373
5. Ogawa S Koga S Kuwabara K Brett J Morrow B Morris SA Bilezikian JP Silverstein SC Stern D Hypoxia-induced increased permeability of endothelial monolayers occurs through lowering of cellular cAMP levels Am J Physiol 1992, 262(3 Pt 1):C546-554. 1312775
6. Tomita I Sawa M Munakata T Tanaka K Kasai S The beneficial effect of dibutyryl cyclic adenosine monophosphate on warm ischemic injury of the rat liver induced by cardiac arrest Transplantation 1996, 62(2):167-173. 10.1097/00007890-199607270-00004 8755811
7. Mizutani A Murakami K Okajima K Kira S Mizutani S Kudo K Takatani J Goto K Hattori S Noguchi T Olprinone reduces ischemia/reperfusion-induced acute renal injury in rats through enhancement of cAMP Shock 2005, 24(3):281-287. 10.1097/01.shk.0000175555.95676.34 16135969
8. Dousa TP Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney Kidney Int 1999, 55(1):29-62. 10.1046/j.1523-1755.1999.00233.x 9893113
9. Skoyles JR Sherry KM Pharmacology, mechanisms of action and uses of selective phosphodiesterase inhibitors Br J Anaesth 1992, 68(3):293-302. 10.1093/bja/68.3.293 1547054
10. Reinhardt RR Chin E Zhou J Taira M Murata T Manganiello VC Bondy CA Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases J Clin Invest 1995, 95(4):1528-1538. 295636 7706458 10.1172/JCI117825
11. Hickey MJ Role of inducible nitric oxide synthase in the regulation of leucocyte recruitment Clin Sci (Lond) 2001, 100(1):1-12. 11115411
12. Chatterjee PK Patel NS Kvale EO Cuzzocrea S Brown PA Stewart KN Mota-Filipe H Thiemermann C Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury Kidney Int 2002, 61(3):862-871. 10.1046/j.1523-1755.2002.00234.x 11849439
13. Asakura H Asamura R Ontachi Y Hayashi T Yamazaki M Morishita E Miyamoto KI Nakao S Selective inducible nitric oxide synthase inhibition attenuates organ dysfunction and elevated endothelin levels in LPS-induced DIC model rats J Thromb Haemost 2005, 3(5):1050-1055. 10.1111/j.1538-7836.2005.01248.x 15869603):
14. Kadkhodaee M Qasemi A Inhibition of inducible nitric oxide synthase reduces lipopolysaccharide-induced renal injury in the rat Clin Exp Pharmacol Physiol 2004, 31(12):842-846. 10.1111/j.1440-1681.2004.04096.x 15659046
15. Chanani NK Cowan DB Takeuchi K Poutias DN Garcia LM del Nido PJ McGowan FX Jr Differential effects of amrinone and milrinone upon myocardial inflammatory signaling Circulation 2002, 106(12 Suppl 1):I284-289. 12354747
16. Suzuki H Sawanishi H Nomura M Shimada T Miyamoto K Effects of 1-benzylxanthines on cyclic AMP phosphodiesterase 4 isoenzyme Biol Pharm Bull 2006, 29(1):131-134. 10.1248/bpb.29.131 16394525
17. Ohlsson K Bjork P Bergenfeldt M Hageman R Thompson RC Interleukin-1 receptor antagonist reduces mortality from endotoxin shock Nature 1990, 348(6301):550-552. 10.1038/348550a0 2147233
18. Cohen JJ Black AJ Wertheim SJ Direct effects of endotoxin on the function of the isolated perfused rat kidney Kidney Int 1990, 37(5):1219-1226. 10.1038/ki.1990.105 2345420
19. Zager RA Johnson AC Lund S Hanson SY Abrass CK Levosimendan protects against experimental endotoxemic acute renal failure Am J Physiol Renal Physiol 2006, 290(6):F1453-1462. 10.1152/ajprenal.00485.2005 16418300
20. Misharin AV Resnenko AB Fidelina OV Grinevich VV Akmaev IG Antidiuretic hormone-V2-receptor-aquaporin-2 system in rat kidneys during acute inflammation Bull Exp Biol Med 2004, 138(5):452-456. 10.1007/ s10517-005-0068-x 15723124
21. Jonassen TE Graebe M Promeneur D Nielsen S Christensen S Olsen NV Lipopolysaccharide-induced acute renal failure in conscious rats: effects of specific phosphodiesterase type 3 and 4 inhibition J Pharmacol Exp Ther 2002, 303(1):364-374. 10.1124/jpet.102.036194 12235272
22. Purswani MU Eckert SJ Arora HK Noel GJ Effect of ciprofloxacin on lethal and sublethal challenge with endotoxin and on early cytokine responses in a murine in vivo model J Antimicrob Chemother 2002, 50(1):51-58. 10.1093/jac/dkf091 12096006
23. Kobayashi T Sugawara Y Ohkubo T Imamura H Makuuchi M Effects of amrinone on hepatic ischemia-reperfusion injury in rats J Hepatol 2002, 37(1):31-38. 10.1016/S0168-8278(02)00084-3 12076859
24. Murray F MacLean MR Pyne NJ Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension Br J Pharmacol 2002, 137(8):1187-1194. 1573609 12466227 10.1038/sj.bjp.0704984
25. Dunkerley HA Tilley DG Palmer D Liu H Jimmo SL Maurice DH Reduced phosphodiesterase 3 activity and phosphodiesterase 3A level in synthetic vascular smooth muscle cells: Implications for use of phosphodiesterase 3 inhibitors in cardiovascular tissues Mol Pharmacol 2002, 61(5):1033-1040. 10.1124/mol.61.5.1033 11961121
26. Kwon KY Jang JH Choi WI Ramachandran S Cho CH Cagle PT Expression of apoptotic nuclei by ultrastructural terminal deoxyribonucleotidyl transferase mediated dUTP nick end labeling and detection of FasL, caspases and PARP protein molecules in cadmium induced acute alveolar cell injury Toxicology 2006, 218(2-3):197-204. 10.1016/j.tox.2005.10.013 16321465
27. Goujon JM Hauet T Menet E Levillain P Babin P Carretier M Histological evaluation of proximal tubule cell injury in isolated perfused pig kidneys exposed to cold ischemia J Surg Res 1999, 82(2):228-233. 10.1006/ jsre.1998.5526 10090834
28. Romani A Dowell E Scarpa A Cyclic AMP-induced Mg2+ release from rat liver hepatocytes, permeabilized hepatocytes, and isolated mitochondria J Biol Chem 1991, 266(36):24376-24384. 1662210
29. Piccoli C Scrima R Ripoli M Di Ianni M Del Papa B D'Aprile A Quarato G Martelli MP Servillo G Ligas C et al Transformation by Retroviral Vectors of Bone Marrow-Derived Mesenchymal Cells Induces Mitochondria-Dependent CAMPSensitive ROS Production Stem Cells 2008, 26(11):2843-2854. 10.1634/stemcells.2007-0885 18787213
30. Pahan K Namboodiri AM Sheikh FG Smith BT Singh I Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes J Biol Chem 1997, 272(12):7786-7791. 10.1074/jbc.272.12.7786 9065441
31. Tiwari MM Brock RW Megyesi JK Kaushal GP Mayeux PR Disruption of renal peritubular blood flow in lipopolysaccharide-induced renal failure: Role of nitric oxide and caspases Am J Physiol Renal Physiol 2005, 289(6):F1324-1332. 10.1152/ajprenal.00124.2005 15998845
32. Gupta A Rhodes GJ Berg DT Gerlitz B Molitoris BA Grinnell BW Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2 Am J Physiol Renal Physiol 2007, 293(1):F245-254. 10.1152/ajprenal.00477.2006 17409278
33. Wu X Guo R Wang Y Cunningham PN The role of ICAM-1 in endotoxin-induced acute renal failure Am J Physiol Renal Physiol 2007, 293(4):F1262-1271. 10.1152/ajprenal.00445.2006 17670897
34. Wang W Faubel S Ljubanovic D Mitra A Falk SA Kim J Tao Y Soloviev A Reznikov LL Dinarello CA et al Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice Am J Physiol Renal Physiol 2005, 288(5):F997-1004. 10.1152/ajprenal.00130.2004 15644489
35. Landry DW Oliver JA The pathogenesis of vasodilatory shock N Engl J Med 2001, 345(8):588-595. 10.1056/NEJMra002709 11529214
36. Wu L Tiwari MM Messer KJ Holthoff JH Gokden N Brock RW Mayeux PR Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice Am J Physiol Renal Physiol 2007, 292(1):F261-268. 10.1152/ajprenal.00263.2006 16926442
37. Heemskerk S Pickkers P Bouw MP Draisma A Hoeven van der JG Peters WH Smits P Russel FG Masereeuw R Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury Clin J Am Soc Nephrol 2006, 1(4):853-862. 10.2215/ CJN.00490206 17699297
38. Churchill PC Bidani AK Schwartz MM Renal effects of endotoxin in the male rat Am J Physiol 1987, 253(2 Pt 2):F244-250. 3303973
39. Kikeri D Pennell JP Hwang KH Jacob AI Richman AV Bourgoignie JJ Endotoxemic acute renal failure in awake rats Am J Physiol 1986, 250(6 Pt 2):F1098-1106. 3521325
40. Kang YH Falk MC Bentley TB Lee CH Distribution and role of lipopolysaccharide in the pathogenesis of acute renal proximal tubule injury Shock 1995, 4(6):441-449. 8608402
41. Mandal AK Lansing M Fahmy A Acute tubular necrosis in hepatorenal syndrome: An electron microscopy study Am J Kidney Dis 1982, 2(3):363-374. 7148828
42. Elenkov IJ Wilder RL Chrousos GP Vizi ES The sympathetic nerve-an integrative interface between two supersystems: The brain and the immune system Pharmacol Rev 2000, 52(4):595-638. 11121511
43. Sternberg EM Neural regulation of innate immunity: A coordinated nonspecific host response to pathogens Nat Rev Immunol 2006, 6(4):318-328. 1783839 16557263 10.1038/nri1810
44. Benotti JR Grossman W Braunwald E Davolos DD Alousi AA Hemodynamic assessment of amrinone. A new inotropic agent N Engl J Med 1978, 299(25):1373-1377. 714115
45. Degerman E Belfrage P Manganiello VC Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3) J Biol Chem 1997, 272(11):6823-6826. 10.1074/jbc.272.11.6823 9102399
46. Karabulut R Sonmez K Sancak B Turkyilmaz Z Demirogullari B Ozen IO Ekingen G Candan S Basaklar AC Kale N Effects of amrinone on bilateral renal ischemia/reperfusion injury Urol Res 2002, 30(3):164-168. 10.1007/ s00240-002-0256-3 12111179
47. Harndahl L Jing XJ Ivarsson R Degerman E Ahren B Manganiello VC Renstrom E Holst LS Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulin J Biol Chem 2002, 277(40):37446-37455. 10.1074/jbc.M205401200 12169692