Lipopolysaccharide-induced acute renal failure in conscious rats: Effects of specific phosphodiesterase type 3 and 4 inhibition

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 1, 2002, Pages 364-374

  Jonassen, Thomas E N ^a   Græbe, Martin ^b   Promeneur, Dominique ^c   Nielsen, Søren ^a   Christensen, Sten ^a   Olsen, Niels V ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Mental Health Services CPH   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; AQUAPORIN 2; CARRIER PROTEIN; LACTIC ACID; LIPOPOLYSACCHARIDE; MILRINONE; PHOSPHODIESTERASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASOPRESSIN;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIURESIS; FEMALE; GLOMERULUS FILTRATION RATE; IMMUNOBLOTTING; KIDNEY COLLECTING TUBULE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SEPSIS; SODIUM TRANSPORT; TACHYCARDIA; WATER INTOXICATION; WATER TRANSPORT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; 4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; ANIMALS; ARGININE VASOPRESSIN; BLOOD GLUCOSE; BLOOD PRESSURE; FEMALE; GLOMERULAR FILTRATION RATE; HEART RATE; KIDNEY FAILURE, ACUTE; LIPOPOLYSACCHARIDES; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, WISTAR;

EID: 0036785531     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.036194     Document Type: Article

References (38)

1. Begany DP, Carcillo JA, Herzer WA, Mi Z, and Jackson EK (1996) Inhibition of type IV phosphodiesterase by Ro 20-1724 attenuates endotoxin-induced acute renal failure. J Pharmacol Exp Ther 278:37-41.
2. Beno DW and Kimura RE (1999) Nonstressed rat model of acute endotoxemia that unmasks the endotoxin-induced TNF-α response. Am J Physiol 276:H671-H678.
3. Bernardin G, Strosberg AD, Bernard A, Mattei M, and Marullo S (1998) β-Adrenergic receptor-dependent and -independent stimulation of adenylate cyclase is impaired during severe sepsis in humans. Intensive Care Med 24:1315-1322.
4. Camussi G, Mariano F, Biancone L, De Martino A, Bussolati B, Montrucchio G, and Tobias PS (1995) Lipopolysaccharide binding protein and CD14 modulate the synthesis of platelet-activating factor by human monocytes and mesangial and endothelial cells stimulated with lipopolysaccharide. J Immunol 155:316-324.
5. Camussi G, Ronco C, Montrucchio G, and Piccoli G (1998) Role of soluble mediators in sepsis and renal failure. Kidney Int 53 (Suppl 66):S38-S42.
6. Carcillo JA, Herzer WA, Mi Z, Thomas NJ, and Jackson EK (1996) Treatment with the type IV phosphodiesterase inhibitor Ro 20-1724 protects renal and mesenteric blood flow in endotoxemic rats treated with norepinephrine. J Pharmacol Exp Ther 279:1197-1204.
7. Carter JA, Clarke TN, Prys-Roberts C, and Spelina KR (1986) Restoration of baroreflex control of heart rate during recovery from anaesthesia. Br J Anaesth 58:415-421.
8. Cavicchi M and Whittle BJ (1999) Potentiation of cytokine induced iNOS expression in the human intestinal epithelial cell line, DLD-1, by cyclic AMP. Gut 45:367-374.
9. Dousa TP (1999) Cyclic-3′, 5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney. Kidney Int. 55:29-62.
10. Ecelbarger CA, Chou CL, Lee AJ, DiGiovanni SR, Verbalis JG, and Knepper MA (1998) Escape from vasopressin-induced antidiuresis: role of vasopressin resistance of the collecting duct. Am J Physiol 274:F1161-F1166.
11. Ecelbarger CA, Nielsen S, Olson BR, Murase T, Baker EA, Knepper MA, and Verbalis JG (1997) Role of renal aquaporins in escape from vasopressin-induced antidiuresis in rat. J Clin Invest 99:1852-1863.
12. Farmer P and Pugin J (2000) β-Adrenergic agonists exert their "anti-inflammatory" effects in monocytic cells through the IκB/NF-κB pathway. Am J Physiol Lung Cell Mol Physiol 279:L675-L682.
13. Fernandez-Llama P, Andrews P, Turner R, Saggi S, Dimari J, Kwon TH, Nielsen S, Safirstein R, and Knepper MA (1999) Decreased abundance of collecting duct aquaporins in post-ischemic renal failure in rats. J Am Soc Nephrol 10:1658-1668.
14. Goncalves dM, V, Singer M, Vargaftig BB, and Chignard M (1998) Effects of rolipram on cyclic AMP levels in alveolar macrophages and lipopolysaccharide-induced inflammation in mouse lung. Br J Pharmacol 123:631-636.
15. Jackson EK, Mi Z, Carcillo JA, Gillespie DG, and Dubey RK (1997) Phosphodiesterases in the rat renal vasculature. J Cardiovasc Pharmacol 30:798-801.
16. Jonassen TE, Christensen S, Kwon TH, Langhoff S, Salling N, and Nielsen S (2000) Renal water handling in rats with decompensated liver cirrhosis. Am J Physiol Renal Physiol 279:F1101-F1109.
17. Jonassen TE, Nielsen S, Christensen S, and Petersen JS (1998) Decreased vasopressin-mediated renal water reabsorption in rats with compensated liver cirrhosis. Am J Physiol 275:F216-F225.
18. Kim GH, Ecelbarger CA, Mitchell C, Packer RK, Wade JB, and Knepper MA (1999) Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop. Am J Physiol 276:F96-F103.
19. Kjaer A, Knigge U, Rouleau A, Garbarg M, and Warberg J (1994) Dehydration-induced release of vasopressin involves activation of hypothalamic histaminergic neurons. Endocrinology 135:675-681.
20. Knotek M, Rogachev B, Wang W, Ecder T, Melnikov V, Gengaro PE, Esson M, Edelstein CL, Dinarello CA, and Schrier RW (2001) Endotoxemic renal failure in mice: role of tumor necrosis factor independent of inducible nitric oxide synthase. Kidney Int 59:2243-2249.
21. Koga S, Morris S, Ogawa S, Liao H, Bilezikian JP, Chen G, Thompson WJ, Ashikaga T, Brett J, and Stern DM (1995) TNF modulates endothelial properties by decreasing cAMP. Am J Physiol 268:C1104-C1113.
22. Kurtz A, Gotz KH, Hamann M, and Wagner C (1998) Stimulation of renin secretion by nitric oxide is mediated by phosphodiesterase 3. Proc Natl Acad Sci USA 95:4743-4747.
23. Kwon TH, Frokiaer J, Fernandez-Llama P, Knepper MA, and Nielsen S (1999) Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: prevention by α-MSH. Am J Physiol 277:F413-F427.
24. Kwon TH, Frokiaer J, Han JS, Knepper MA, and Nielsen S (2000) Decreased abundance of major Na(+) transporters in kidneys of rats with ischemia-induced acute renal failure. Am J Physiol Renal Physiol 278:F925-F939.
25. Leyssac PP, Frederiksen O, Holstein-Rathlou NH, Alfrey AC, and Christensen P (1994) Active lithium transport by rat renal proximal tubule: a micropuncture study. Am J Physiol 267:F86-F93.
26. Losonczy G, Bloch JF, Samsell L, Schoenl M, Venuto R, and Baylis C (1997) Impact of surgery on nitric oxide in rats: evidence for activation of inducible nitric oxide synthase. Kidney Int 51:1943-1949.
27. Lugon JR, Boim MA, Ramos OL, Ajzen H, and Schor N (1989) Renal function and glomerular hemodynamics in male endotoxemic rats. Kidney Int 36:570-575.
28. Nielsen S, Kwon TH, Christensen BM, Promeneur D, Frokiaer J, and Marples D (1999) Physiology and pathophysiology of renal aquaporins. J Am Soc Nephrol 10:647-663.
29. Nielsen S, Terris J, Andersen D, Ecelbarger C, Frokiaer J, Jonassen T, Marples D, Knepper MA, and Petersen JS (1997) Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct. Proc Natl Acad Sci USA 94:5450-5455.
30. Parry GC and Mackman N (1997) Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-κB-mediated transcription. J Immunol 159:5450-5456.
31. Petersen JS, Shalmi M, Lam HR, and Christensen S (1991) Renal response to furosemide in conscious rats: effects of acute instrumentation and peripheral sympathectomy. J Pharmacol Exp Ther 258:1-7.
32. Sandner P, Kornfeld M, Ruan X, Arendshorst WJ, and Kurtz A (1999) Nitric oxide/cAMP interactions in the control of rat renal vascular resistance. Circ Res 84:186-192.
33. Schaller MD, Waeber B, Nussberger J, and Brunner HR (1985) Angiotensin II, vasopressin and sympathetic activity in conscious rats with endotoxemia. Am J Physiol 249:H1086-H1092.
34. Schlondorff D, Nelson PJ, Luckow B, and Banas B (1997) Chemokines and renal disease. Kidney Int 51:610-621.
35. Schwartz D, Mendonca M, Schwartz I, Xia Y, Satriano J, Wilson CB, and Blantz RC (1997) Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest 100:439-448.
36. Thomas NJ, Carcillo JA, Herzer WA, Mi Z, and Jackson EK (2001) Chronic type IV phosphodiesterase inhibition protects glomerular filtration rate and renal and mesenteric blood flow in a zymosan-induced model of multiple organ dysfunction syndrome treated with norepinephrine. J Pharmacol Exp Ther 296:168-174.
37. Thomsen K and Shirley DG (1997) The validity of lithium clearance as an index of sodium and water delivery from the proximal tubules. Nephron 77:125-138.
38. Zhong H, Voll RE, and Ghosh S (1998) Phosphorylation of NF-KB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1:661-671.