Olprinone reduces ischemia/reperfusion-induced acute renal injury in rats through enhancement of cAMP

Shock

Volumn 24, Issue 3, 2005, Pages 281-287

  Mizutani, Akio ^a,c   Murakami, Kazunori ^b   Okajima, Kenji ^b   Kira, Shin Ichiro ^c   Mizutani, Sachiko ^c   Kudo, Kyosuke ^c   Takatani, Junji ^c   Goto, Koji ^c   Hattori, Seiji ^c   Noguchi, Takayuki ^a,c  

^a OITA UNIVERSITY HOSPITAL   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c OITA UNIVERSITY   (Japan)

Author keywords

Cytokine induced neutrophil chemoattractant; Endothelial cell damage; Phosphodiesterase 3 inhibitor; Renal dysfunction; Tumor necrosis factor

Indexed keywords

BUCLADESINE; CHEMOATTRACTANT; CREATININE; CYCLIC AMP; CYCLIC AMP DERIVATIVE; CYTOKINE; INTERLEUKIN 8; LOPRINONE; MYELOPEROXIDASE; PHOSPHODIESTERASE III INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD LEVEL; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEGRADATION; DRUG EFFECT; DRUG INFUSION; DRUG MECHANISM; DRUG SPECIFICITY; KIDNEY BLOOD FLOW; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY MEDULLA; KIDNEY TUBULE NECROSIS; LEUKOCYTE ACTIVATION; LIVER HISTOLOGY; MALE; NONHUMAN; RAT; REPERFUSION INJURY; TREATMENT OUTCOME; UREA NITROGEN BLOOD LEVEL;

ANIMALS; BLOOD UREA NITROGEN; CARDIOTONIC AGENTS; CREATININE; CYCLIC AMP; HEMODYNAMIC PROCESSES; IMIDAZOLES; INFLAMMATION; INTERLEUKIN-8; KIDNEY; LEUKOCYTES; LYMPHOCYTE ACTIVATION; MALE; NECROSIS; NEUTROPHILS; PEROXIDASE; PHOSPHODIESTERASE INHIBITORS; PYRIDONES; RATS; RATS, WISTAR; REPERFUSION INJURY; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 24644439945     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000175555.95676.34     Document Type: Article

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