Genetic regulatory networks of nephrogenesis: Deregulation of WT1 splicing by benzo(a)pyrene

Birth Defects Research Part C - Embryo Today: Reviews

Volumn 87, Issue 2, 2009, Pages 192-197

  Ramos, Kenneth S ^a,b   Nanez, Adrian ^a  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; SECRETED FRIZZLED RELATED PROTEIN 1; SOMATOMEDIN; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; WT1 PROTEIN;

CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; GENE REGULATORY NETWORK; KIDNEY DEVELOPMENT; KIDNEY FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVIEW; RNA SPLICING; XENOBIOTIC METABOLISM;

ADULT; ALTERNATIVE SPLICING; ANIMALS; BENZO(A)PYRENE; CARCINOGENS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; HUMANS; KIDNEY; MICE; MICE, KNOCKOUT; MORPHOGENESIS; PREGNANCY; RATS; RECEPTOR CROSS-TALK; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; WT1 PROTEINS; YOUNG ADULT;

EID: 67649341452     PISSN: 1542975X     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrc.20148     Document Type: Review

References (69)

1. Andreasen EA, Mathew LK, Tanguay RL. 2006. Regenerative growth is impacted by tcdd: gene expression analysis reveals extracellular matrix modulation. Toxicol Sci 92:254-269. (Pubitemid 43985808)
2. Barker DJ. 2007. The origins of the developmental origins theory. J Internal Medicine 261:412-417. (Pubitemid 46587729)
3. Barouki R, Coumoul X, Fernandez-Salguero PM. 2007. The aryl hydrocarbon receptor, more than a xenobiotic- interacting protein. FEBS Lett 581:3608-3615. (Pubitemid 47080995)
4. Bentley D. 2002. The mrna assembly line: transcription and processing machines in the same factory. Curr Opin Cell Biol 14:336-342. (Pubitemid 34626972)
5. BeruBe K, Balharry D, Sexton K, et al. 2007. Combustion-derived nanoparticles: mechanisms of pulmonary toxicity. Clin Exp Pharmacol Physiol 34:1044-1050. (Pubitemid 47274565)
6. Bush PG, Mayhew TM, Abramovich DR, et al. 2000a. Maternal cigarette smoking and oxygen diffusion across the placenta. Placenta 21:824-833.
7. Bush PG, Mayhew TM, Abramovich DR, et al. 2000b. A quantitative study on the effects of maternal smoking on placental morphology and cadmium concentration. Placenta 21:247-256. (Pubitemid 30240792)
8. Celsi G, Kistner A, Aizman R, et al. 1998. Prenatal dexamethasone causes oligonephronia, sodium retention, and higher blood pressure in the offspring. Pediatric Res 44:317-322. (Pubitemid 28389985)
9. Chang X, Fan Y, Karyala S, et al. 2007. Ligand-independent regulation of transforming growth factor β1 expression and cell cycle progression by the aryl hydrocarbon receptor. Mol Cell Biol 27:6127-6139. (Pubitemid 47326700)
10. Chesire DR, Dunn TA, Ewing CM, et al. 2004. Identification of aryl hydrocarbon receptor as a putative wnt/β-catenin pathway target gene in prostate cancer cells. Cancer Res 64:2523-2533. (Pubitemid 38523909)
11. Cohen HT, Bossone SA, Zhu G, et al. 1997. Sp1 is a critical regulator of the wilms' tumor-1 gene. J Biol Chem 272:2901-2913. (Pubitemid 27053340)
12. Davies RC, Calvio C, Bratt E, et al. 1998. Wt1 interacts with the splicing factor u2af65 in an isoform-dependent manner and can be incorporated into spliceosomes. Genes Dev 12:3217-3225. (Pubitemid 28496266)
13. Duncan DM, Burgess EA, Duncan I. 1998. Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor. Genes Dev 12:1290-1303. (Pubitemid 28213405)
14. Duong Van Huyen J-P, Viltard M, Nehiri T, et al. 2007. Expression of matrix metalloproteinases mmp-2 and mmp-9 is altered during nephrogenesis in fetuses from diabetic rats. Lab Invest 87:680-689. (Pubitemid 46920106)
15. Eperon LP, Graham IR, Griffiths AD, Eperon IC. 1988. Effects of rna secondary structure on alternative splicing of pre-mrna: is folding limited to a region behind the transcribing rna polymerase? Cell 54:393-401.
16. Falahatpisheh MH, Ramos KS. 2003. Ligand-activated ahr signaling leads to disruption of nephrogenesis and altered wilms' tumor suppressor mrna splicing. Oncogene 22:2160-2171. (Pubitemid 36539566)
17. Fernandez-Salguero P, Pineau T, Hilbert DM, et al. 1995. Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding ah receptor. Science 268:722-726.
18. Gavras I, Gavras H. 2002. Angiotensin ii as a cardiovascular risk factor. J Hum Hypertens 16 (Suppl 2):S2-S6. (Pubitemid 34537390)
19. Hahn ME. 2002. Aryl hydrocarbon receptors: diversity and evolution. Chem Biol Interact 141:131-160. (Pubitemid 35223209)
20. Hahn ME, Karchner SI, Evans BR, et al. 2006. Unexpected diversity of aryl hydrocarbon receptors in non-mammalian vertebrates: insights from comparative genomics. J Exp Zool A Comp Exp Biol 305:693-706. (Pubitemid 44358297)
21. Hammes A, Guo J-K, Lutsch G, et al. 2001. Two splice variants of the wilms' tumor 1 gene have distinct functions during sex determination and nephron formation. Cell 106:319-329. (Pubitemid 32772616)
22. Hastie ND. 2001. Life, sex, and wt1 isoforms - three amino acids can make all the difference. Cell 106:391. (Pubitemid 32786981)
23. Hillegass JM, Murphy KA, Villano CM, White LA. 2006. The impact of aryl hydrocarbon receptor signaling on matrix metabolism: implications for development and disease. Biol Chem 387:1159-1173.
24. Hosono S, Gross I, English MA, et al. 2000. E-cadherin is a wt1 target gene. J Biol Chem 275:10943-10953. (Pubitemid 30212731)
25. Ikuta T, Kawajiri K. 2006. Zinc finger transcription factor slug is a novel target gene of aryl hydrocarbon receptor. Exp Cell Res 312:3585-3594. (Pubitemid 44470776)
26. Johnson CD, Balagurunathan Y, Tadesse MG, et al. 2004. Unraveling gene-gene interactions regulated by ligands of the aryl hydrocarbon receptor. Environ Health Perspect 112:403-412. (Pubitemid 38404549)
27. Kanwar YS, Ota K, Yang Q, et al. 1999. Role of membrane-type matrix metalloproteinase 1 (mt-1-mmp), mmp- 2, and its inhibitor in nephrogenesis. Am J Physiol 277:F934-F947. (Pubitemid 30046069)
28. Kato S, Sato T, Watanabe T, et al. 2005. Function of nuclear sex hormone receptors in gene regulation. Cancer Chemother Pharmacol 56:4-9. (Pubitemid 41755685)
29. Knutti D, Kressler D, Kralli A. 2001. Regulation of the transcriptional coactivator pgc-1 via mapk-sensitive interaction with a repressor. Proc Natl Acad Sci USA 98:9713-9718. (Pubitemid 32769369)
30. Lahvis GP, Lindell SL, Thomas RS, et al. 2000. Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice. Proc Natl Acad Sci USA 97:10442-10447. (Pubitemid 30707285)
31. Lahvis GP, Pyzalski RW, Glover E, et al. 2005. The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse. Mol Pharmacol 67:714-720. (Pubitemid 40365318)
32. Lummus ZL, Henningsen G. 1995. Modulation of t-cell ontogeny by transplacental benzo(a)pyrene. Int J Immunopharmacol 17:339-350.
33. Lund AK, Goens MB, Kanagy NL, Walker MK. 2003. Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin ii, endothelin-1, and mean arterial blood pressure. Toxicol Appl Pharmacol 193:177-187. (Pubitemid 37476433)
34. Lund AK, Goens MB, Nunez BA, Walker MK. 2006. Characterizing the role of endothelin-1 in the progression of cardiac hypertrophy in aryl hydrocarbon receptor (ahr) null mice. Toxicol Appl Pharmacol 212:127-135.
35. MacKenzie KM, Angevine DM. 1981. Infertility in mice exposed in utero to benzo(a)pyrene. Biol Reprod 24:183-191. (Pubitemid 11144796)
36. Mah SP, Saueressig H, Goulding M, et al. 2000. Kidney development in cadherin-6 mutants: delayed mesenchyme- to-epithelial conversion and loss of nephrons. Dev Biol 223:38-53. (Pubitemid 30439517)
37. Marchand A, Tomkiewicz C, Marchandeau JP, et al. 2005. 2,3,7,8-tetra-chlorodibenzo- p-dioxin induces insulin- like growth factor binding protein-1 gene expression and counteracts the negative effect of insulin. Mol Pharmacol 67:444-452.
38. Menzie CA, Potocki BB, Santodonato J. 1992a. Ambient concentrations and exposure to carcinogenic pah's in the environment. Environ Sci Technol 26:1278-1284.
39. Menzie CA, Potocki BB, Santodonato J. 1992b. Exposure to carcinogenic pahs in the environment. Environ Sci Technol 26:1278-1284. (Pubitemid 23365931)
40. Murphy LJ, Barron DJ. 1993. The igfs and their binding proteins in murine development. Mol Reprod Dev 35:376-381. (Pubitemid 23227025)
41. Nanez A, Alejandro NF, Falahatpisheh MH, et al. 2005. Disruption of glomerular cell-cell and cell-matrix interactions in hydrocarbon nephropathy. Am J Physiol Renal Physiol 289:F1291-F1303. (Pubitemid 41681364)
42. Natoli TA, McDonald A, Alberta JA, et al. 2002. A mammal-specific exon of wt1 is not required for development or fertility. Mol Cell Biol 22:4433-4438. (Pubitemid 34556609)
43. Ng SP, Silverstone AE, Lai Z-W, Zelikoff JT. 2006. Effects of prenatal exposure to cigarette smoke on offspring tumor susceptibility and associated immune mechanisms. Toxicol Sci 89:135-144. (Pubitemid 43013762)
44. Nieburg P, Marks JS, McLaren NM, Remington PL. 1985. The fetal tobacco syndrome. JAMA 253:2998-2999.
45. Nieto MA. 2002. The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol 3:155-166. (Pubitemid 37237138)
46. Nwagwu MO, Cook A, Langley-Evans SC. 2000. Evidence of progressive deterioration of renal function in rats exposed to a maternal low-protein diet in utero. Br J Nutr 83:79-85. (Pubitemid 30052868)
47. Ohtake F, Baba A, Takada I, et al. 2007. Dioxin receptor is a ligand-dependent e3 ubiquitin ligase. Nature 446:562-566. (Pubitemid 46514731)
48. Ota K, Stetler-Stevenson WG, Yang Q, et al. 1998. Cloning of murine membrane- type-1-matrix metalloproteinase (mt-1-mmp) and its metanephric developmental regulation with respect to mmp-2 and its inhibitor. Kidney Int 54:131-142. (Pubitemid 28288027)
49. Oxburgh L, Chu GC, Michael SK, Robertson EJ. 2004. Tgfβ superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development 131:4593-4605. (Pubitemid 39409699)
50. Peters JM, Narotsky MG, Elizondo G, et al. 1999. Amelioration of tcdd-induced teratogenesis in aryl hydrocarbon receptor (ahr)-null mice. Toxicol Sci 47:86-92. (Pubitemid 29214235)
51. Pope CA. 2007. Mortality effects of longer term exposures to fine particulate air pollution: review of recent epidemiological evidence. Inhal Toxicol 19:33-38. (Pubitemid 47450704)
52. Qin H, Zhai Z, Powell-Coffman JA. 2006. The caenorhabditis elegans ahr-1 transcription complex controls expression of soluble guanylate cyclase genes in the urx neurons and regulates aggregation behavior. Dev Biol 298:606-615. (Pubitemid 44441196)
53. Rebagliato M, Florey CDV, Bolumar F. 1995. Exposure to environmental tobacco smoke in nonsmoking pregnant women in relation to birth weight. AmJ Epidemiol 142:531-537.
54. Roberts GC, Gooding C, Mak HY, et al. 1998. Co-transcriptional commitment to alternative splice site selection. Nucleic Acids Res 26:5568-5572. (Pubitemid 28554723)
55. Rodriquez JW, Kirlin WG, Wirsiy YG, et al. 1999. Maternal exposure to benzo(a)pyrene alters development of t lymphocytes in offspring. Immunopharmacol Immunotoxicol 21:379-396. (Pubitemid 29207220)
56. Sanders MW, Fazzi GE, Janssen GMJ, et al. 2005. High sodium intake increases blood pressure and alters renal function in intrauterine growth-retarded rats. Hypertension 46:71-75. (Pubitemid 40946493)
57. Sasaki S, Kondo T, Sata F, et al. 2006. Maternal smoking during pregnancy and genetic polymorphisms in the ah receptor, cyp1a1 and gstm1 affect infant birth size in Japanese subjects. Mol Hum Reprod 12:77-83.
58. Schmidt JV, Su GH-T, Reddy JK, et al. 1996. Characterization of a murine ahr null allele: involvement of the ah receptor in hepatic growth and development. Proc Natl Acad Sci USA 93:6731-6736. (Pubitemid 26230378)
59. Sim EUH, Smith A, Szilagi E, et al. 2002. Wnt-4 regulation by the wilms' tumor suppressor gene, wt1. Oncogene 21:2948-2960. (Pubitemid 34522894)
60. Sonnenberg A, Linders CJ, Modderman PW, et al. 1990. Integrin recognition of different cell-binding fragments of laminin (p1, e3, e8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment e8. J Cell Biol 110:2145-2155. (Pubitemid 20183171)
61. Stark K, Vainio S, Vassileva G, McMahon AP. 1994. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by wnt-4. Nature 372:679.
62. Valentovic MA, Alejandro N, Betts Carpenter A, et al. 2006. Streptozotocin (stz) diabetes enhances benzo(alpha) pyrene induced renal injury in sprague dawley rats. Toxicol Lett 164:214-220. (Pubitemid 44235982)
63. Wada J, Liu ZZ, Alvares K, et al. 1993. Cloning of cdna for the alpha subunit of mouse insulin-like growth factor i receptor and the role of the receptor in metanephric development. Proc Natl Acad Sci USA 90:10360-10364. (Pubitemid 23328312)
64. Wagner N, Wagner K-D, Hammes A, et al. 2005. A splice variant of the wilms' tumour suppressor wt1 is required for normal development of the olfactory system. Development 132:1327-1336. (Pubitemid 40528792)
65. Wells PG, Kim PM, Laposa RR, et al. 1997. Oxidative damage in chemical teratogenesis. Mutat Res 396:65-78. (Pubitemid 28012643)
66. Winn LM, Wells PG. 1997. Evidence of embryonic prostaglandin h synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of macromolecules in phenytoin and benzo(a)pyrene teratogenesis. Free Radic Biol Med 22:607-621. (Pubitemid 27043398)
67. Yamazaki T, Komuro I, Kudoh S, et al. 1996. Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem 271:3221-3228. (Pubitemid 26055625)
68. Yoshino K, Rubin JS, Higinbotham KG, et al. 2001. Secreted frizzled-related proteins can regulate metanephric development. Mech Dev 102:45-55. (Pubitemid 32273586)
69. Zandi-Nejad K, Luyckx VA, Brenner BM. 2006. Adult hypertension and kidney disease: the role of fetal programming. Hypertension 47:502-508. (Pubitemid 43843866)