Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: Characterization and comparison of recombinant zebrafish serine hydroxymethyltransferases

Drug Metabolism and Disposition

Volumn 35, Issue 11, 2007, Pages 2127-2137

  Chang, Wen Ni ^a   Tsai, Jen Ning ^b   Chen, Bing Hung ^c   Huang, Huei Sheng ^a   Fu, Tzu Fun ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

FOLINIC ACID; METHOTREXATE; METHYLTRANSFERASE; SERINE HYDROXYMETHYLTRANSFERASE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG METABOLISM; GENE SEQUENCE; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; GENE EXPRESSION PROFILING; GLYCINE HYDROXYMETHYLTRANSFERASE; GREEN FLUORESCENT PROTEINS; HUMANS; ISOENZYMES; LEUCOVORIN; METHOTREXATE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; TETRAHYDROFOLATES; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; ESCHERICHIA COLI; MAMMALIA;

EID: 35548971594     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.016840     Document Type: Article

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