Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: A cohort study

Journal of Trauma - Injury, Infection and Critical Care

Volumn 66, Issue 1, 2009, Pages 115-122

  Shalhub, Sherene ^a   Junker, Christopher E ^a   Imahara, Scott D ^a   Mindrinos, Michael N ^b   Dissanaike, Sharmila ^c   O'keefe, Grant E ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

Allelic association; HtSNP; Polymorphism; SNP

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CD14 ANTIGEN; INTERLEUKIN 1; TLR4 PROTEIN, HUMAN;

ADULT; ARTICLE; BLUNT TRAUMA; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE; GENE CLUSTER; GENE FREQUENCY; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; PENETRATING TRAUMA; PRIORITY JOURNAL; RISK FACTOR; SEPSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TOLL LIKE RECEPTOR 4 GENE; TRAUMATIC SHOCK; ALLELE; BURN; CHI SQUARE DISTRIBUTION; COHORT ANALYSIS; GENETICS; INJURY SCALE; MULTIPLE ORGAN FAILURE; MUTATION; PROSPECTIVE STUDY; RISK; SHOCK; STATISTICAL MODEL;

ALLELES; ANTIGENS, CD14; BURNS; CHI-SQUARE DISTRIBUTION; COHORT STUDIES; FEMALE; GENETIC VARIATION; GENOTYPE; HAPLOTYPES; HUMANS; INJURY SEVERITY SCORE; INTERLEUKIN-1; INTERLEUKIN-6; LOGISTIC MODELS; MALE; MULTIPLE ORGAN FAILURE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RISK; SHOCK; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649194968     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181938d50     Document Type: Article

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