Impact of glucose concentration on cardiac ventricular repolarization under IKr/IKs blocking agents

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 2, 2009, Pages 210-220

  Hreiche, Raymond ^a,b   Plante, Isabelle ^a,b   David, Louis Philippe ^b   Simard, Chantale ^c,d   Turgeon, Jacques ^a,b   Drolet, Benoit ^c,d  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d LAVAL UNIVERSITY   (Canada)

Author keywords

Cardiac repolarization; Diabetes; Drugs; P glycoprotein; QT prolongation

Indexed keywords

CHROMANOL 293B; DOFETILIDE; GLUCOSE; GLYCOPROTEIN P;

ACTION POTENTIAL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFICACY; DRUG MECHANISM; GUINEA PIG; HEART REPOLARIZATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPOGLYCEMIA; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; QT PROLONGATION;

ACTION POTENTIALS; ANIMALS; BUFFERS; CELL LINE; CHROMANS; ETHER-A-GO-GO POTASSIUM CHANNELS; GLUCOSE; GUINEA PIGS; HEART VENTRICLES; HUMANS; ION CHANNEL GATING; PATCH-CLAMP TECHNIQUES; PERFUSION; PHENETHYLAMINES; POTASSIUM CHANNEL BLOCKERS; SULFONAMIDES;

CAVIA;

EID: 67649105359     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.02.004     Document Type: Article

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