Update on ARDS: Beyond the low tidal volume

American Journal of the Medical Sciences

Volumn 337, Issue 5, 2009, Pages 360-367

  Dernaika, Tarek A ^a   Keddissi, Jean I ^a   Kinasewitz, Gary T ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

ARDS; PEEP; Respiratory failure; Steriods; Ventilation

Indexed keywords

ACTIVATED PROTEIN C; ALBUMIN; DROTRECOGIN; FLUOROCARBON; FUROSEMIDE; LUNG SURFACTANT; METHYLPREDNISOLONE; NITRIC OXIDE; PLACEBO; PLASMA PROTEIN; OXYGEN; STEROID; SURFACTANT;

ADULT RESPIRATORY DISTRESS SYNDROME; AIRWAY PRESSURE; AIRWAY PRESSURE RELEASE VENTILATION; ARTIFICIAL VENTILATION; BODY POSTURE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; DOSE RESPONSE; DRUG MEGADOSE; FLUID BALANCE; FLUID THERAPY; HUMAN; HYPOPROTEINEMIA; LIQUID VENTILATION; LONG TERM CARE; LOW DRUG DOSE; NON INVASIVE PROCEDURE; NONHUMAN; OPEN LUNG VENTILATION; PATHOPHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; PROGNOSIS; REVIEW; TIDAL VOLUME; TREATMENT OUTCOME; BIOLOGICAL MODEL; LUNG; METABOLISM; PHYSIOLOGY;

CLINICAL TRIALS AS TOPIC; HUMANS; LUNG; MODELS, BIOLOGICAL; NITRIC OXIDE; OXYGEN; POSITIVE-PRESSURE RESPIRATION; PROGNOSIS; RESPIRATORY DISTRESS SYNDROME, ADULT; STEROIDS; SURFACE-ACTIVE AGENTS; TIDAL VOLUME; TREATMENT OUTCOME;

EID: 67649090314     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e318195493e     Document Type: Review

References (109)

1. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-8.
2. Ashbaugh DG, Bigelow DB, Petty TL, et al. Acute respiratory distress in adults. Lancet 1967;2:319-23.
3. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000;342:1334-49.
4. Pugin J, Verghese G, Widmer MC, et al. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med 1999;27: 304-12.
5. Pratt PC, Vollmer RT, Shelburne JD, et al. Pulmonary morphology in a multihospital collaborative extracorporeal membrane oxygenation project. I. Light microscopy. Am J Pathol 1979;95:191-214.
6. Ware L, Matthay M. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;163:1376-83.
7. Verghese GM, Ware LB, Matthay BA, et al. Alveolar epithelial fluid transport and the resolution of clinically severe hydrostatic pulmonary edema. J Appl Physiol 1999;87:1301-12.
8. Greene KE, Wright JR, Steinberg KP, et al. Serial changes in surfactant-associated proteins in lung and serum before and after onset of ARDS. Am J Respir Crit Care Med 1999;160:1843-50.
9. Lewis JF, Jobe AH. Surfactant and the adult respiratory distress syndrome. Am Rev Respir Dis 1993;147:218-33.
10. Veldhuizen RA, Hearn SA, Lewis JF, et al. Surface-area cycling of different surfactant preparations: SP-A and SP-B are essential for large aggregate integrity. Biochem J 1994;300:519-24.
11. Higuchi R, Lewis J, Ikegami M. In vitro conversion of surfactant subtypes is altered in alveolar surfactant isolated from injured lungs. Am Rev Respir Dis 1992;145:1416-20.
12. Kiiski R, Takala J, Kari A, et al. Effect of tidal volume on gas exchange and oxygen transport in the adult respiratory distress syndrome. Am Rev Respir Dis 1992;146:1131-5.
13. Gattinoni L, Pesenti A, Avalli L, et al. Pressure-volume curve of total respiratory system in acute respiratory failure: computed tomographic scan study. Am Rev Respir Dis 1987;136:730-6.
14. Steltzer H, Krafft P, et al. Right ventricular function and oxygen transport patterns in patients with acute respiratory distress syndrome. Anaesthesia 1994;49:1039-45.
15. Steltzer H, Krafft P, Fridrich P, et al. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149:818-24.
16. Matamis D, Lemaire F, Harf A, et al. Redistribution of pulmonary blood flow induced by positive end-expiratory pressure and dopamine infusion in acute respiratory failure. Am Rev Respir Dis 1984; 129: 39-44.
17. Ralph DD, Robertson HT, Weaver LJ, et al. Distribution of ventilation and perfusion during positive end-expiratory pressure in the adult respiratory distress syndrome. Am Rev Respir Dis 1985;131: 54-60.
18. Dhainaut J, Aouate P, Brunet FP, et al. Circulatory effect of positive end-expiratory pressure in patients with acute lung injury. In: Scharf SM, Cassidy SS, editors. Heart-lung interaction in health and disease. New York (NY): Marcel Dekker; 1989. p. 809-38.
19. Muscedere JG, Mullen JB, Gan K, et al. Tidal ventilation at low airway pressures can augment lung injury. Am J Respir Crit Care Med 1994;149:1327-34.
20. Fu Z, Costello ML, Tsukimoto K, et al. High lung volume increases stress failure in pulmonary capillaries. J Appl Physiol 1992;73:123-33.
21. Carlton DP, Cummings JJ, Scheerer RG, et al. Lung overexpansion increases pulmonary microvascular protein permeability in young lambs. J Appl Physiol 1990;69:577-83.
22. Amato MB, Barbas CS, Medeiros DM, et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998;338:347-54.
23. Brower RG, Lanken PN, Maclntyre N, et al. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med 2004;351:327-36.
24. Mercat A, Richard JC, Vielle B, et al. Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA 2008;299: 646-55.
25. Meade MO, Cook DJ, Guyatt GH, et al. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA 2008;299:637-45.
26. Piehl M, Brown R. Use of extreme position changes in acute respiratory failure. Crit Care Med 1976;4:13-4.
27. Albert RK, Leasa D, Sanderson M, et al. The prone position improves arterial oxygenation and reduces shunt in oleic acid-induced acute lung injury. Am Rev Respir Dis 1987;135:628-33.
28. Pelosi P, Tubiolo D, Mascheroni D, et al. Effects of the prone position on respiratory mechanics and gas-exchange during acute lung injury. Am J Respir Crit Care Med 1998;157:387-93.
29. Pelosi P, Brazzi L, Gattinoni L. Prone position in acute respiratory distress syndrome. Eur Respir J 2002;20:1017-28.
30. Lamm WJ, Graham MM, Albert RK. Mechanism by which the prone position improves oxygenation in acute lung injury. Am J Respir Crit Care Med 1994;150:184-93.
31. Gattinoni L, Tognoni G, Pcsenti A, et al. Effect of prone positioning on the survival of patients with acute respiratory failure. N Engl J Med 2001;345:568-73.
32. 2 with prone position is predictive of improved outcome in acute respiratory distress syndrome. Crit Care Med 2003;31:2727-33.
33. Guerin C, Guaillard S, Lemasson S, et al. Effects of systematic prone positioning in hypoxemic acute respiratory failure: a randomized controlled trial. JAMA 2004;292:2379-87.
34. Curley MA, Hibberd PL, Fineman LD, et al. Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA 2005;294:229-37.
35. Petty TL, Reiss OK, Paul GW, et al. Characteristics of pulmonary surfactant in adult respiratory syndrome associated with trauma and shock. Am Rev Respir Dis 1977;115:531-6.
36. Petty TL, Silvers GW, Paul GW, et al. Abnormalities in lung elastic properties and surfactant function in adult respiratory distress syndrome. Chest 1979;75:571-4.
37. Hallman M, Spragg R, Harrell JH, et al. Evidence of lung surfactant abnormality in respiratory failure. Study of bronchoalveolar lavage phospholipids, surface activity, phospholipase activity, and plasma myoinositol. J Clin Invest 1982;70:673-83.
38. Hafner D, Germann PG, Hauschke D. Effects of rSP-C surfactant on oxygenation and histology in a rat-lung-lavage model of acute lung injury. Am J Respir Crit Care Med 1998;158:270-8.
39. Jobe A. Drug therapy: pulmonary surfactant therapy. N Engl J Med 1993;328:861-8.
40. Anzueto A, Baughman RP, Guntupalli KK, et al. Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. N Engl J Med 1996;334:1417-21.
41. Walmrath D, Grimminger F, Pappert D, et al. Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on gas exchange and haemodynamics. Eur Respir J 2002; 19: 805-10.
42. Spragg RG, Lewis JF, Walmrath HD, et al. Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome. N Engl J Med 2004;351:884-92.
43. Palmer RM, Ferrige AG, Moncada S, et al. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-6.
44. Kaisers U, Busch T, Deja M, et al. Selective pulmonary vasodilation in acute respiratory distress syndrome. Crit Care Med 2003;31(suppl 4):S337-S342.
45. Gerlach H, Rossaint R, Pappert D, et al. Time-course and dose-response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome. Eur J Clin Invest 1993;23:499-502.
46. Rimar S, Gillis CN. Selective pulmonary vasodilation by inhaled nitric oxide is due to hemoglobin inactivation. Circulation 1993;88: 2884-7.
47. Taylor RW, Zimmerman JL, Dellinger RP, et al. Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. JAMA 2004;291:1603-9.
48. Dellinger RP, Zimmerman JL, Taylor RW, et al. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled Nitric Oxide in ARDS Study Group. Crit Care Med 1998;26:15-23.
49. Lundin S, Mang H, Smithies M, et al. Inhalation of nitric oxide in acute lung injury: results of a European multicentre study. The European Study Group of Inhaled Nitric Oxide. Intensive Care Med 1999;25:911-9.
50. Papazian L, Bregeon F, Gaillat F, et al. Respective and combined effects of prone position and inhaled nitric oxide in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1998;157: 580-5.
51. Borelli M, Lampati L, Vascotto E, et al. Hemodynamic and gas exchange response to inhaled nitric oxide and prone positioning in acute respiratory distress syndrome patients. Crit Care Med 2000;28: 2707-12.
52. Ricard JD, Lemaire F. Liquid ventilation. Curr Opin Crit Care 2001;7:8-14.
53. Dreyfuss D, Martin-Lefevre L, Saumon G. Hyperinflation-induced lung injury during alveolar flooding in rats: effect of perfluorocarbon instillation. Am J Respir Crit Care Med 1999;159:1752-7.
54. Croce MA, Fabian TC, Patton JH Jr, et al. Partial liquid ventilation decreases the inflammatory response in the alveolar environment of trauma patients. J Trauma 1998;45:273-80.
55. Baba A, Kim YK, Zhang H, et al. Perfluorocarbon blocks tumor necrosis factor-alpha-induced interleukin-8 release from alveolar epithelial cells in vitro. Crit Care Med 2000;28:1113-8.
56. Merz U, Klosterhalfen B, Hausler M, et al. Partial liquid ventilation reduces release of leukotriene B4 and interleukin-6 in bronchoalveolar lavage in surfactant-depleted newborn pigs. Pediatr Res 2002;51: 183-9.
57. Morris KP, Cox PN, Mazer CD, et al. Distribution of pulmonary blood flow in the perfluorocarbon-filled lung. Intensive Care Med 2000;26:756-63.
58. Cox PN, Frndova H, Tan PS, et al. Concealed air leak associated with large tidal volumes in partial liquid ventilation. Am J Respir Crit Care Med 1997;156:992-7.
59. Tutiincii AS, Faithfull NS, Lachmann B. Intratracheal perfluorocarbon administration combined with mechanical ventilation in experimental respiratory distress syndrome: dose-dependent improvement of gas exchange. Crit Care Med 1993;21:962-9.
60. Bartlett R, Croce M. A phase II randomized, controlled trial of partial liquid ventilation in adult patients with acute hypoxemic respiratory failure [abstract]. Crit Care Med 1997;25:A45.
61. Melo J, Anzueto A. Liquid ventilation. Intensive Care Med 1999;25: 420-1.
62. Hirschl RB, Croce M, Gore D, et al. Prospective, randomized, controlled pilot study of partial liquid ventilation in adult acute respiratory distress syndrome. Am J Respir Crit Care Med 2002;165: 781-7.
63. Davies M, Sargent P. Partial liquid ventilation for preventing death and morbidity in adults with acute lung injury and ARDS. Cochrane Database Syst Rev 2004;2:CD003707.
64. Froese AC, Bryan AB. Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 1974;41:242-55.
65. Putensen C, Mutz N, Putensen-Himmer G, et al. Spontaneous breathing during ventilatory support improves ventilation-perfusion distributions in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1999;159:1241-8.
66. Putensen C, Zech S, Wrigge H, et al. Long-term effects of spontaneous breathing during ventilatory support in patients with acute lung injury. Am J Respir Crit Care Med 2001;164:43-9.
67. Lim C, Koh Y, Park W, et al. Mechanistic scheme and effect of "extended sigh" as a recruitment maneuver in patients with acute respiratory distress syndrome: a preliminary study. Crit Care Med 2001;29:1255-60.
68. Richard J, Maggiore S, Jonson B, et al. Influence of tidal volume on alveolar recruitment. Respective role of PEEP and a recruitment maneuver. Am J Respir Crit Care Med 2001;163:1609-13.
69. Foti G, Cereda M, Sparacino ME, et al. Effects of periodic lung recruitment maneuvers on gas exchange and respiratory mechanics in mechanically ventilated acute respiratory distress syndrome (ARDS) patients. Intensive Care Med 2000;26:501-7.
70. Grasso S, Mascia L, Del Turco M, et al. Effects of recruiting maneuvers in patients with acute respiratory distress syndrome ventilated with protective ventilatory strategy. Anesthesiology 2002;96: 795-802.
71. Simmons R, Berdine G, Seidenfeld JJ, et al. Fluid balance and the adult respiratory distress syndrome. Am Rev Respir Dis 1987;135: 924-9.
72. Humphrey H, Hall J, Sznajder I, et al. Improved survival in ARDS patients associated with a reduction in pulmonary capillary wedge pressure. Chest 1990;1997:1176-80.
73. Alsous F, Khamiees M, DeGirolamo A, et al. Negative fluid balance predicts survival in patients with septic shock: a retrospective pilot study. Chest 2000;117:1749-54.
74. Navarrete-Navarro P, Rodriguez A, Reynolds N, et al. Acute respiratory distress syndrome among trauma patients: trends in ICU mortality, risk factors, complications and resource utilization. Intensive Care Med 2001;27:1133-40.
75. Martin GS, Mangialardi RJ, Wheeler AP, et al. Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury. Crit Care Med 2002;30:2175-82.
76. The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006;354:2564-75.
77. Brochard L, Mancebo J, Wysocki M, et al. Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 1995;333:817-22.
78. Kramer N, Meyer TJ, Meharg J, et al. Randomized, prospective trial of noninvasive position pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 1995;151:1799-806.
79. Antonelli M, Conti G, Rocco M, et al. A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 1998;339: 429-35.
80. Delclaux C, L'Her E, Alberti C, et al. Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: a randomized controlled trial. JAMA 2000;284:2352-60.
81. Martin TJ, Hovis JD, Costantino JP, et al. A randomized, prospective evaluation of noninvasive ventilation for acute respiratory failure. Am J Respir Crit Care Med 2000;161:807-13.
82. Antonelli M, Conti G, Bufi M, et al. Noninvasive ventilation for treatment of acute respiratory failure in patients undergoing solid organ transplantation: a randomized trial. JAMA 2000;283:235-41.
83. Hilbert G, Gruson D, Vargas F, et al. Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure. N Engl J Med 2001;344:481-7.
84. Katzenstein A, Askin F. Surgical pathology of non-neoplastic lung disease. Philadelphia: Saunders; 1982.
85. Tomashefski J. Pulmonary pathology of the adult respiratory distress syndrome. Clin Chest Med 1990;11:593-619.
86. Meduri GU, Tolley EA, Chrousos GP, et al. Prolonged methylpred-nisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am J Respir Crit Care Med 2002;165:983-91.
87. Bernard GR, Luce JM, Sprung CL, et al. High-dose corticosteroids in patients with the adult respiratory distress syndrome. N Engl J Med 1987;317:1565-70.
88. Luce JM, Montgomery AB, Marks JD, et al. Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am Rev Respir Dis 1988;136:62-8.
89. Ashbaugh D, Maier R. Idiopathic pulmonary fibrosis in adult respiratory distress syndrome. Diagnosis and treatment. Arch Surg 1985; 120:530-5.
90. Hooper R, Kearl R. Established ARDS treated with a sustained course of adrenocortical steroids. Chest 1990;97:138-43.
91. Hooper R, Kearl R. Established adult respiratory distress syndrome successfully treated with corticosteroids. South Med J 1996;89:359-64.
92. Braude S, Haslam P, Hughes D, et al. Chronic adult respiratory distress syndrome-a role for corticosteroids? Crit Care Med 1992;20: 1187-9.
93. Biffl WL, Moore FA, Moore EE, et al. Are corticosteroids salvage therapy for refractory acute respiratory distress syndrome? Am J Surg 1995;170:591-5.
94. Meduri GU, Belenchia JM, Estes RJ, et al. Fibroproliferative phase of ARDS. Clinical findings and effects of corticosteroids. Chest 1991;100:943-52.
95. Meduri GU, Chinn AJ, Leeper KV, et al. Corticosteroid rescue treatment of progressive fibroproliferation in late ARDS. Patterns of response and predictors of outcome. Chest 1994;105:1516-27.
96. Meduri GU, Hcadley AS, Golden E, et al. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial. JAMA 1998;280:159-65.
97. Steinberg KP, Hudson LD, Goodman RB, et al. Yin HL. Gelsolin: calcium-and polyphosphoinositide-regulated actin-modulating protein. Bioessays 1987;7:176-9.; The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006;354:1671-84.
98. Meduri GU, Golden E, Freire AX, et al. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest 2007;131:954-63.
99. Meduri GU, Marik PE, Chrousos GP, et al. Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature. Intensive Care Med 2008;34:61-9.
100. Marik PE, Pastores SM, Annane D, et al. Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008;36:1937-49.
101. Annane D, Scbille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002;288:862-71.
102. Briegel J, Forst H, Haller M, et al. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 1999;27:723-32.
103. Matthay MA, Ware LB. Plasma protein C levels in patients with acute lung injury: prognostic significance. Crit Care Med 2004; 32(suppl 5):S229-S232.
104. Liu KD, Levitt J, Zhuo H, et al. Randomized clinical trial of activated protein c for the treatment of acute lung injury. Am J Respir Crit Care Med 2008;178:618-23.
105. Eisner MD, Thompson T, Hudson LD, et al. Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;164:231-6.
106. Angus DC, Musthafa AA, Clermont G, et al. Quality-adjusted survival in the first year after the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;163:1389-94.
107. Herridge MS, Cheung AM, Tansey CM, et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003;348:683-93.
108. Orme J Jr, Romney JS, Hopkins RO, et al. Pulmonary function and health-related quality of life in survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med 2003;167:690-4.
109. Hopkins RO, Weaver LK, Collingridge D, et al. Two-year cognitive, emotional, and quality-of-life outcomes in acute respiratory distress syndrome. Am J Respir Crit Care Med 2005;171:340-7.