Distribution of pulmonary blood flow in the perfluorocarbon-filled lung

Intensive Care Medicine

Volumn 26, Issue 6, 2000, Pages 756-763

  Morris, K P ^a   Cox, P N ^a   Frndova, H ^a   McKerlie, C ^a   Mazer, C D ^b   Wolfe, R ^c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Haemodynamics; Liquid ventilation; Microspheres; Perfluorocarbon; Pulmonary blood flow

Indexed keywords

FLUOROCARBON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GAS EXCHANGE; HEMODYNAMICS; HUMAN; LUNG BLOOD FLOW; LUNG INJURY; LUNG PERFUSION; LUNG VENTILATION; MALE; NONHUMAN; ORGAN DISTRIBUTION; OXYGENATION; SWINE;

EID: 0033936274     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340051243     Document Type: Article

References (25)

1. 1. Curtis SE, Peek JT, Kelly DR (1993) Partial liquid breathing with perflubron improves arterial oxygenation in acute canine lung injury. J Appl Physiol 75: 2696-2702
2. 2. Nesti FD, Fuhrman BP, Steinhorn DM, Papo MS, et al. (1994) Perfluorocarbon-associated gas exchange in gastric aspiration. Crit Care Med 22: 1445-1452
3. 3. Papo MC, Paczan PR, Fuhrman BP, Steinhorn DM, et al. (1996) Perfluorocarbon-associated gas exchange improves oxygenation, lung mechanics and survival in a model of adult respiratory distress syndrome. Crit Care Med 24: 466-474
4. 4. Lamm WJE, Graham MM, Albert RK (1994) Mechanism by which the prone position improves oxygenation in acute lung injury. Am J Respir Crit Care Med 150: 184-193
5. 5. Foley CK, Dowhy MS, Fuhrman BP, Hernan LJ, et al. (1995) Vertical distribution of airway pressure during gas or liquid inflation of the liquid filled lung (abstract). Am J Respir Crit Care Med 151 (suppl 4): A445
6. 6. Malo J, Ali J, Wood LDH (1984) How does positive end-expiratory pressure reduce intrapulmonary shunt in canine pulmonary oedema. J Appl Physiol 57: 1002-1010
7. 7. Lowe CA, Shaffer TH (1986) Pulmonary vascular resistance in the fluorocarbon-filled lung. J Appl Physiol 60: 154-159
8. 8. Curtis SE, Fuhrman BP, Rowland DF, DeFrancisis M, et al. (1991) Cardiac output during liquid (perfluorocarbon) breathing in newborn piglets. Crit Care Med 19: 225-230
9. 9. Lowe C, Tuma RF, Sivieri EM, Shaffer TH (1979) Liquid ventilation: cardiovascular adjustments with secondary hyperlactatemia and acidosis. J Appl Physiol 47: 1051-1057
10. 10. Heymann MA, Payne BD, Hoffman JL, Rudolph AM (1977) Blood flow measurements with radionuclide-labelled particles. Prog Cardiovasc Dis 20: 55-78
11. 11. Matthews JNS, Altman DC, Campbell MJ, Royston P (1990) Analysis of serial measurements in medical research. BMJ 300: 230-235
12. 12. Stata, Stata User's Guide, Release 5 (1997) College Station, Texas, pp 235-239
13. 13. West JB, Dollery CT, Naimark A (1964) Distribution of blood flow in isolated lung; relation to vascular and alveolar pressures. J Appl Physiol 19: 713-724
14. 14. West JB, Dollery CT (1965) Distribution of blood flow and the pressure-flow relations of the whole lung. J Appl Physiol 20: 175-183
15. 15. Hakim TS, Lisbona R, Dean GW (1987) Gravity nondependent distribution of pulmonary blood flow. In: Will JA, Dawson CA, Weir EK, Buckner CK (eds) The pulmonary circulation in health and disease. Academic Press, New York, pp 231-248
16. 16. Glenny RW, Polissar L, Robertson HT (1991) Relative contribution of gravity to pulmonary perfusion heterogeneity. J Appl Physiol 71: 2449-2452
17. 17. D'Angelo E, Agostini E (1975) Vertical gradients of pleural and transpulmonary pressure with liquid-filled lungs. Respir Physiol 23: 159-173
18. 18. West JB, Dollery CT, Matthews CME, Zardini P (1965) Distribution of blood flow and ventilation in saline-filled lung. J Appl Physiol 20: 1107-1117
19. 19. Muir AL, Hall DL, Despas P, Hogg JC (1972) Distribution of blood flow in the lungs in acute pulmonary edema in dogs. J Appl Physiol 33: 763-769
20. 20. Lamm WJE, Graham MM, Albert RK (1996) Partial liquid ventilation improves oxygenation by redistributing perfusion to ventral lung regions (abstract). Am J Respir Crit Care Med 153 (suppl 4): A12
21. 21. Doctor A, Ibla JC, Grenier BM, Zurakowski D, et al. (1998) Pulmonary blood flow distribution during partial liquid ventilation. J Appl Physiol 84: 1540-1550
22. 22. Quintel M, Hirschl RB, Roth H, Loose R, et al. (1998) Computer tomographic assessment of perfluorocarbon and gas distribution during partial liquid ventilation for acute respiratory failure. Am J Respir Crit Care Med 158 : 249-255
23. 23. Cox PN, Morris K, Frndova H, Babyn P, Bryan AC (1996) Relative distribution of gas and perfluorocarbon (PFC) during partial liquid ventilation (abstract). Pediatr Res 39: 45A
24. 24. Hernan LJ, Fuhrman BP, Papo MC, Steinhorn DM, et al. (1995) Cardiorespiratory effects of perfluorocarbon-associated gas exchange at reduced oxygen concentrations. Crit Care Med 23: 553-559
25. 25. Gattinoni L, Pesenti A, Bombino M, Baglioni S, et al. (1988) Relationships between lung computed tomographic density, gas exchange and PEEP in acute respiratory failure. Anesthesiology 69: 824-832