A leukemic plasmacytoid dendritic cell line, PMDC05, with the ability to secrete IFN-α by stimulation via Toll-like receptors and present antigens to naïve T cells

Leukemia Research

Volumn 33, Issue 9, 2009, Pages 1224-1232

  Narita, Miwako ^a,b   Watanabe, Norihiro ^a   Yamahira, Akie ^a   Hashimoto, Shigeo ^b   Tochiki, Nozomi ^a   Saitoh, Anri ^a,b   Kaji, Masami ^a   Nakamura, Takeshi ^a   Furukawa, Tatsuo ^c   Toba, Ken ^b   Fuse, Ichiro ^c   Aizawa, Yoshifusa ^b   Takahashi, Masuhiro ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^c NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

Author keywords

Antigen presenting ability; Antigen uptake; IFN ; IL 12; IRF1; IRF7; Plasmacytoid dendritic cell leukemia; Toll like receptors

Indexed keywords

ALPHA INTERFERON; CD123 ANTIGEN; CD33 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CD86 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; HLA DR ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 3; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ANTIGEN PRESENTATION; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; HUMAN CELL; INFLUENZA VIRUS; LEUKEMIA; LEUKEMIA CELL LINE; PATHOPHYSIOLOGY; PLASMACYTOID DENDRITIC CELL LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANTIGENS; BASE SEQUENCE; CELL LINE, TUMOR; DENDRITIC CELLS; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERFERON-ALPHA; KARYOTYPING; LEUKEMIA, PLASMA CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS;

EID: 67549094654     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.03.047     Document Type: Article

References (38)

1. Soumelis V., and Liu Y.J. From plasmacytoid to dendritic cell: morphological and functional switches during plasmacytoid pre-dendritic cell differentiation. Eur J Immunol 36 (2006) 2286-2292
2. Brody J.P., Allen S., Schulman P., et al. Acute agranular CD4-positive natural killer cell leukemia. Comprehensive clinicopathologic studies including virologic and in vitro culture with inducing agents. Cancer 75 (1995) 2474-2483
3. Kameoka J., Ichinohasama R., Tanaka M., et al. A cutaneous agranular CD2- CD4+ CD56+ "lymphoma": report of two cases and review of the literature. Am J Clin Pathol 110 (1998) 478-488
4. Petrella T., Dalac S., Maynadie M., et al. CD4+ CD56+ cutaneous neoplasms: a distinct hematological entity? Groupe Francais d'Etude des Lymphomes Cutanes (GFELC). Am J Surg Pathol 23 (1999) 137-146
5. Kimura S., Kakazu N., Kuroda J., et al. Agranular CD4+CD56+ blastic natural killer leukemia/lymphoma. Ann Hematol 80 (2001) 228-231
6. Knudsen H., Gronbaek K., thor Straten P., et al. A case of lymphoblastoid natural killer (NK)-cell lymphoma: association with the NK-cell receptor complex CD94/NKG2 and TP53 intragenic deletion. Br J Dermatol 146 (2002) 148-153
7. Rakozy C.K., Mohamed A.N., Vo T.D., et al. CD56+/CD4+ lymphomas and leukemias are morphologically, immunophenotypically, cytogenetically, and clinically diverse. Am J Clin Pathol 116 (2001) 168-176
8. Chaperot L., Bendriss N., Manches O., et al. Identification of a leukemic counterpart of the plasmacytoid dendritic cells. Blood 97 (2001) 3210-3217
9. Feuillard J., Jacob M.C., Valensi F., et al. Clinical and biologic features of CD4(+)CD56(+) malignancies. Blood 99 (2002) 1556-1563
10. Petrella T., Comeau M.R., Maynadie M., et al. 'Agranular CD4+ CD56+ hematodermic neoplasm' (blastic NK-cell lymphoma) originates from a population of CD56+ precursor cells related to plasmacytoid monocytes. Am J Surg Pathol 26 (2002) 852-862
11. Jacob M.C., Chaperot L., Mossuz P., et al. CD4+ CD56+ lineage negative malignancies: a new entity developed from malignant early plasmacytoid dendritic cells. Haematologica 88 (2003) 941-955
12. Chaperot L., Blum A., Manches O., et al. Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells. J Immunol 176 (2006) 248-255
13. Maeda T., Murata K., Fukushima T., et al. A novel plasmacytoid dendritic cell line, CAL-1, established from a patient with blastic natural killer cell lymphoma. Int J Hematol 81 (2005) 148-154
14. Narita M., Kuroha T., Watanabe N., et al. Plasmacytoid dendritic cell leukemia with potent antigen presenting ability. Acta Haematol 120 (2008) 91-99
15. Narita M., Takahashi M., Liu A., et al. Leukemia blast-induced T-cell anergy demonstrated by leukemia-derived dendritic cells in acute myelogenous leukemia. Exp Hematol 29 (2001) 709-719
16. Osman Y., Takahashi M., Zheng Z., et al. Generation of bcr-abl specific cytotoxic T-lymphocytes by using dendritic cells pulsed with bcr-abl (b3a2) peptide: its applicability for donor leukocyte transfusions in marrow grafted CML patients. Leukemia 13 (1999) 166-174
17. Zheng Z., Takahashi M., Narita M., et al. Generation of dendritic cells from adherent cells of cord blood by culture with granulocyte-macrophage colony-stimulating factor, interleukin-4, and tumor necrosis factor-alpha. J Hematother Stem Cell Res 9 (2000) 453-464
18. Kohrgruber N., Halanek N., Groger M., et al. Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines. J Immunol 163 (1999) 3250-3259
19. Garnache-Ottou F., Feuillard J., and Saas P. Plasmacytoid dendritic cell leukaemia/lymphoma: towards a well defined entity?. Br J Haematol 136 (2007) 539-548
20. Kadowaki N., Ho S., Antonenko S., et al. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J Exp Med 194 (2001) 863-869
21. Jarrossay D., Napolitani G., Colonna M., Sallusto F., and Lanzavecchia A. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol 31 (2001) 3388-3393
22. Ito T., Wang Y.H., and Liu Y.J. Plasmacytoid dendritic cell precursors/type I interferon-producing cells sense viral infection by Toll-like receptor (TLR) 7 and TLR9. Springer Semin Immunopathol 26 (2005) 221-229
23. Bendriss-Vermare N., Barthelemy C., Durand I., et al. Human thymus contains IFN-α-producing CD11c(-), myeloid CD11c(+), and mature interdigitating dendritic cells. J Clin Invest 107 (2001) 835-844
24. Schotte R., Rissoan M.C., Bendriss-Vermare N., et al. The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development. Blood 101 (2003) 1015-1023
25. Pavlovic J., Haller O., and Staeheli P. Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle. J Virol 66 (1992) 2564-2569
26. Urosevic M., Conrad C., Kamarashev J., et al. CD4+CD56+ hematodermic neoplasms bear a plasmacytoid dendritic cell phenotype. Hum Pathol 36 (2005) 1020-1024
27. Takaoka A., Tamura T., and Taniguchi T. Interferon regulatory factor family of transcription factors and regulation of oncogenesis. Cancer Sci 99 (2008) 467-478
28. Gabriele L., and Ozato K. The role of the interferon regulatory factor (IRF) family in dendritic cell development and function. Cytokine Growth Factor Rev 18 (2007) 503-510
29. Donohoe M.E., and Blomberg B.B. The 14.1 surrogate light chain promoter has lineage- and stage-restricted activity. J Immunol 158 (1997) 1681-1691
30. Chicha L., Jarrossay D., and Manz M.G. Clonal type I interferon-producing and dendritic cell precursors are contained in both human lymphoid and myeloid progenitor populations. J Exp Med 200 (2004) 1519-1524
31. Ishikawa F., Niiro H., Iino T., et al. The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways. Blood 110 (2007) 3591-3660
32. Ju X.S., Hacker C., Scherer B., et al. Immunoglobulin-like transcripts ILT2, ILT3 and ILT7 are expressed by human dendritic cells and down-regulated following activation. Gene 331 (2004) 159-164
33. Krug A., Towarowski A., Britsch S., et al. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur J Immunol 31 (2001) 3026-3037
34. Ito T., Kanzler H., Duramad O., Cao W., and Liu Y.J. Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells. Blood 107 (2006) 2423-2431
35. Grouard G., Rissoan M.C., Filgueira L., Durand I., Banchereau J., and Liu Y.J. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J Exp Med 185 (1997) 1101-1111
36. Krug A., Rothenfusser S., Hornung V., et al. Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells. Eur J Immunol 31 (2001) 2154-2163
37. Chaperot L., Perrot I., Jacob M.C., et al. Leukemic plasmacytoid dendritic cells share phenotypic and functional features with their normal counterparts. Eur J Immunol 34 (2004) 418-426
38. Garnache-Ottou F., Chaperot L., Biichle S., et al. Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells. Blood 105 (2005) 1256-1264