-
1
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov, R. 2001. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1: 135-145.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 135-145
-
-
Medzhitov, R.1
-
2
-
-
33646183566
-
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
-
Beutler, B., Z. Jiang, P. Georgel, K. Crozat, B. Croker, S. Rutschmann, X. Du, and K. Hoebe. 2006. Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu. Rev. Immunol. 24: 353-389.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 353-389
-
-
Beutler, B.1
Jiang, Z.2
Georgel, P.3
Crozat, K.4
Croker, B.5
Rutschmann, S.6
Du, X.7
Hoebe, K.8
-
3
-
-
34447645301
-
How important are Toll-like receptors for antimicrobial responses?
-
Carpenter, S., and L. A. O'Neill. 2007. How important are Toll-like receptors for antimicrobial responses? Cell. Microbiol. 9: 1891-1901.
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 1891-1901
-
-
Carpenter, S.1
O'Neill, L.A.2
-
4
-
-
33744823520
-
Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis
-
Gibson, F. C., 3rd, H. Yumoto, Y. Takahashi, H. H. Chou, and C. A. Genco. 2006. Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis. J. Dent. Res. 85: 106-121.
-
(2006)
J. Dent. Res.
, vol.85
, pp. 106-121
-
-
Gibson III, F.C.1
Yumoto, H.2
Takahashi, Y.3
Chou, H.H.4
Genco, C.A.5
-
5
-
-
33845462504
-
Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis: Activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption
-
Burns, E., G. Bachrach, L. Shapira, and G. Nussbaum. 2006. Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis: Activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption. J. Immunol. 177: 8296-8300. (Pubitemid 44893789)
-
(2006)
Journal of Immunology
, vol.177
, Issue.12
, pp. 8296-8300
-
-
Burns, E.1
Bachrach, G.2
Shapira, L.3
Nussbaum, G.4
-
6
-
-
33748473184
-
Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus
-
Hajishengallis, G., R. I. Tapping, E. Harokopakis, S.-I. Nishiyama, P. Ratti, R. E. Schifferle, E. A. Lyle, M. Triantafilou, K. Triantafilou, and F. Yoshimura. 2006. Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus. Cell. Microbiol. 8: 1557-1570.
-
(2006)
Cell. Microbiol.
, vol.8
, pp. 1557-1570
-
-
Hajishengallis, G.1
Tapping, R.I.2
Harokopakis, E.3
Nishiyama, S.-I.4
Ratti, P.5
Schifferle, R.E.6
Lyle, E.A.7
Triantafilou, M.8
Triantafilou, K.9
Yoshimura, F.10
-
7
-
-
12844264795
-
Cytokine profiling of macrophages exposed to Porphyromonas gingivalis, its lipopolysaccharide, or its FimA protein
-
Zhou, Q., T. Desta, M. Fenton, D. T. Graves, and S. Amar. 2005. Cytokine profiling of macrophages exposed to Porphyromonas gingivalis, its lipopolysaccharide, or its FimA protein. Infect. Immun. 73: 935-943.
-
(2005)
Infect. Immun.
, vol.73
, pp. 935-943
-
-
Zhou, Q.1
Desta, T.2
Fenton, M.3
Graves, D.T.4
Amar, S.5
-
8
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
O'Neill, L. A., and A. G. Bowie. 2007. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 7: 353-364.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
9
-
-
0028144158
-
Inactivation of the Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats
-
Malek, R., J. G. Fisher, A. Caleca, M. Stinson, C. J. van Oss, J. Y. Lee, M. I. Cho, R. J. Genco, R. T. Evans, and D. W. Dyer. 1994. Inactivation of Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats. J. Bacteriol. 176: 1052-1059. (Pubitemid 24060122)
-
(1994)
Journal of Bacteriology
, vol.176
, Issue.4
, pp. 1052-1059
-
-
Malek, R.1
Fisher, J.G.2
Caleca, A.3
Stinson, M.4
Van Oss, C.J.5
Lee, J.-Y.6
Cho -, M.I.7
Genco, R.J.8
Evans, R.T.9
Dyer, D.W.10
-
10
-
-
2942544238
-
Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice
-
Gibson, F. C., 3rd, C. Hong, H. H. Chou, H. Yumoto, J. Chen, E. Lien, J. Wong, and C. A. Genco. 2004. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 109: 2801-2806.
-
(2004)
Circulation
, vol.109
, pp. 2801-2806
-
-
Gibson III, F.C.1
Hong, C.2
Chou, H.H.3
Yumoto, H.4
Chen, J.5
Lien, E.6
Wong, J.7
Genco, C.A.8
-
11
-
-
0031766801
-
Life below the gum line: Pathogenic mechanisms of Porphyromonas gingivalis
-
Lamont, R. J., and H. F. Jenkinson. 1998. Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol. Mol. Biol. Rev. 62: 1244-1263.
-
(1998)
Microbiol. Mol. Biol. Rev.
, vol.62
, pp. 1244-1263
-
-
Lamont, R.J.1
Jenkinson, H.F.2
-
12
-
-
0037265493
-
Molecular interaction of Porphyromonas gingivalis with host cells: Implication for the microbial pathogenesis of periodontal disease
-
Amano, A. 2003. Molecular interaction of Porphyromonas gingivalis with host cells: implication for the microbial pathogenesis of periodontal disease. J. Periodontol. 74: 90-96.
-
(2003)
J. Periodontol.
, vol.74
, pp. 90-96
-
-
Amano, A.1
-
13
-
-
0035184263
-
Bacterial fimbriae and their peptides activate human gingival epithelial cells through Toll-like receptor 2
-
Asai, Y., Y. Ohyama, K. Gen, and T. Ogawa. 2001. Bacterial fimbriae and their peptides activate human gingival epithelial cells through Toll-like receptor 2. Infect. Immun. 69: 7387-7395.
-
(2001)
Infect. Immun.
, vol.69
, pp. 7387-7395
-
-
Asai, Y.1
Ohyama, Y.2
Gen, K.3
Ogawa, T.4
-
14
-
-
28244498667
-
Peptide mapping of bacterial fimbrial epitopes interacting with pattern recognition receptors
-
Hajishengallis, G., P. Ratti, and E. Harokopakis. 2005. Peptide mapping of bacterial fimbrial epitopes interacting with pattern recognition receptors. J. Biol. Chem. 280: 38902-38913.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38902-38913
-
-
Hajishengallis, G.1
Ratti, P.2
Harokopakis, E.3
-
15
-
-
1342302486
-
Fimbriated Porphyromonas gingivalis is more efficient than fimbria-deficient P. gingivalis in entering human dendritic cells in vitro and induces an inflammatory Th1 effector response
-
Jotwani, R., and C. W. Cutler. 2004. Fimbriated Porphyromonas gingivalis is more efficient than fimbria-deficient P. gingivalis in entering human dendritic cells in vitro and induces an inflammatory Th1 effector response. Infect. Immun. 72: 1725-1732.
-
(2004)
Infect. Immun.
, vol.72
, pp. 1725-1732
-
-
Jotwani, R.1
Cutler, C.W.2
-
16
-
-
33846805500
-
Differential activation of human gingival epithelial cells and monocytes by Porphyromonas gingivalis fimbriae
-
Eskan, M. A., G. Hajishengallis, and D. F. Kinane. 2007. Differential activation of human gingival epithelial cells and monocytes by Porphyromonas gingivalis fimbriae. Infect. Immun. 75: 892-898.
-
(2007)
Infect. Immun.
, vol.75
, pp. 892-898
-
-
Eskan, M.A.1
Hajishengallis, G.2
Kinane, D.F.3
-
17
-
-
42149120757
-
Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs
-
Davey, M., X. Liu, T. Ukai, V. Jain, C. Gudino, F. C. Gibson, 3rd, D. Golenbock, A. Visintin, and C. A. Genco. 2008. Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs. J. Immunol. 180: 2187-2195.
-
(2008)
J. Immunol.
, vol.180
, pp. 2187-2195
-
-
Davey, M.1
Liu, X.2
Ukai, T.3
Jain, V.4
Gudino, C.5
Gibson III, F.C.6
Golenbock, D.7
Visintin, A.8
Genco, C.A.9
-
18
-
-
51649098149
-
Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function
-
Hajishengallis, G., M. Wang, S. Liang, M. Triantafilou, and K. Triantafilou. 2008. Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function. Proc. Natl. Acad. Sci. USA 105: 13532-13537.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 13532-13537
-
-
Hajishengallis, G.1
Wang, M.2
Liang, S.3
Triantafilou, M.4
Triantafilou, K.5
-
20
-
-
33744903384
-
TLR2 transmodulates monocyte adhesion and transmigration via Rac1- And PI3K-mediated inside-out signaling in response to Porphyromonas gingivalis fimbriae
-
Harokopakis, E., M. H. Albzreh, M. H. Martin, and G. Hajishengallis. 2006. TLR2 transmodulates monocyte adhesion and transmigration via Rac1- and PI3K-mediated inside-out signaling in response to Porphyromonas gingivalis fimbriae. J. Immunol. 176: 7645-7656. (Pubitemid 43849065)
-
(2006)
Journal of Immunology
, vol.176
, Issue.12
, pp. 7645-7656
-
-
Harokopakis, E.1
Albzreh, M.H.2
Martin, M.H.3
Hajishengallis, G.4
-
21
-
-
17444394875
-
Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol- 3-kinase
-
Harokopakis, E., and G. Hajishengallis. 2005. Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol- 3-kinase. Eur. J. Immunol. 35: 1201-1210.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1201-1210
-
-
Harokopakis, E.1
Hajishengallis, G.2
-
22
-
-
12844278116
-
Oral mucosal endotoxin tolerance induction in chronic periodontitis
-
Muthukuru, M., R. Jotwani, and C. W. Cutler. 2005. Oral mucosal endotoxin tolerance induction in chronic periodontitis. Infect. Immun. 73: 687-694.
-
(2005)
Infect. Immun.
, vol.73
, pp. 687-694
-
-
Muthukuru, M.1
Jotwani, R.2
Cutler, C.W.3
-
23
-
-
28644452355
-
The expression profile of lipopolysaccharide-binding protein, membrane-bound CD14, and toll-like receptors 2 and 4 in chronic periodontitis
-
Ren, L., W. K. Leung, R. P. Darveau, and L. Jin. 2005. The expression profile of lipopolysaccharide-binding protein, membrane-bound CD14, and toll-like receptors 2 and 4 in chronic periodontitis. J. Periodontol. 76: 1950-1959.
-
(2005)
J. Periodontol.
, vol.76
, pp. 1950-1959
-
-
Ren, L.1
Leung, W.K.2
Darveau, R.P.3
Jin, L.4
-
24
-
-
0347511008
-
Macrophages, inflammation, and atherosclerosis
-
Linton, M. F., and S. Fazio. 2003 Macrophages, inflammation, and atherosclerosis. Int. J. Obes. Relat. Metab. Disord. 27 Suppl 3: S35-S40.
-
(2003)
Int. J. Obes. Relat. Metab. Disord.
, vol.27
, Issue.SUPPL. 3
-
-
Linton, M.F.1
Fazio, S.2
-
25
-
-
34848855747
-
Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo
-
Hajishengallis, G., M.-A. K. Shakhatreh, M. Wang, and S. Liang. 2007. Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo. J. Immunol. 179: 2359-2367.
-
(2007)
J. Immunol.
, vol.179
, pp. 2359-2367
-
-
Hajishengallis, G.1
Shakhatreh, M.-A.K.2
Wang, M.3
Liang, S.4
-
26
-
-
34848908962
-
Fimbrial proteins of Porphyromonas gingivalis mediate in vivo virulence and exploit TLR2 and complement receptor 3 to persist in macrophages
-
Wang, M., M.-A. K. Shakhatreh, D. James, S. Liang, S.-i. Nishiyama, F. Yoshimura, D. R. Demuth, and G. Hajishengallis. 2007. Fimbrial proteins of Porphyromonas gingivalis mediate in vivo virulence and exploit TLR2 and complement receptor 3 to persist in macrophages. J. Immunol. 179: 2349-2358.
-
(2007)
J. Immunol.
, vol.179
, pp. 2349-2358
-
-
Wang, M.1
Shakhatreh, M.-A.K.2
James, D.3
Liang, S.4
Nishiyama, S.-I.5
Yoshimura, F.6
Demuth, D.R.7
Hajishengallis, G.8
-
27
-
-
0021678531
-
Purification and characterization of a novel type of fimbriae from the oral anaerobe Bacteroides gingivalis
-
Yoshimura, F., K. Takahashi, Y. Nodasaka, and T. Suzuki. 1984. Purification and characterization of a novel type of fimbriae from the oral anaerobe Bacteroides gingivalis. J. Bacteriol. 160: 949-957.
-
(1984)
J. Bacteriol.
, vol.160
, pp. 949-957
-
-
Yoshimura, F.1
Takahashi, K.2
Nodasaka, Y.3
Suzuki, T.4
-
28
-
-
34147114196
-
Ganglioside GD1a is an essential coreceptor for toll-like receptor 2 signaling in response to the B subunit of Type IIB enterotoxin
-
Liang, S., M. Wang, R. I. Tapping, V. Stepensky, H. F. Nawar, M. Triantafilou, K. Triantafilou, T. D. Connell, and G. Hajishengallis. 2007. Ganglioside GD1a is an essential coreceptor for toll-like receptor 2 signaling in response to the B subunit of Type IIB enterotoxin. J. Biol. Chem. 282: 7532-7542.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 7532-7542
-
-
Liang, S.1
Wang, M.2
Tapping, R.I.3
Stepensky, V.4
Nawar, H.F.5
Triantafilou, M.6
Triantafilou, K.7
Connell, T.D.8
Hajishengallis, G.9
-
29
-
-
0031913035
-
Cell activation mediated by glycosylphosphatidylinositol-anchored or transmembrane forms of CD14
-
Pugin, J., V. V. Kravchenko, J. D. Lee, L. Kline, R. J. Ulevitch, and P. S. Tobias. 1998. Cell activation mediated by glycosylphosphatidylinositol- anchored or transmembrane forms of CD14. Infect. Immun. 66: 1174-1180.
-
(1998)
Infect. Immun.
, vol.66
, pp. 1174-1180
-
-
Pugin, J.1
Kravchenko, V.V.2
Lee, J.D.3
Kline, L.4
Ulevitch, R.J.5
Tobias, P.S.6
-
30
-
-
15544380329
-
Toll-like receptor 2 mediates cellular activation by the B subunits of type II heat-labile enterotoxins
-
Hajishengallis, G., R. I. Tapping, M. H. Martin, H. Nawar, E. A. Lyle, M. W. Russell, and T. D. Connell. 2005. Toll-like receptor 2 mediates cellular activation by the B subunits of type II heat-labile enterotoxins. Infect. Immun. 73: 1343-1349.
-
(2005)
Infect. Immun.
, vol.73
, pp. 1343-1349
-
-
Hajishengallis, G.1
Tapping, R.I.2
Martin, M.H.3
Nawar, H.4
Lyle, E.A.5
Russell, M.W.6
Connell, T.D.7
-
31
-
-
18144362027
-
Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-κB
-
Loiarro, M., C. Sette, G. Gallo, A. Ciacci, N. Fanto, D. Mastroianni, P. Carminati, and V. Ruggiero. 2005. Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-κB. J. Biol. Chem. 280: 15809-15814.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15809-15814
-
-
Loiarro, M.1
Sette, C.2
Gallo, G.3
Ciacci, A.4
Fanto, N.5
Mastroianni, D.6
Carminati, P.7
Ruggiero, V.8
-
32
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-β-induced STAT1α/β- dependent gene expression in macrophages
-
Toshchakov, V., B. W. Jones, P. Y. Perera, K. Thomas, M. J. Cody, S. Zhang, B. R. Williams, J. Major, T. A. Hamilton, M. J. Fenton, and S. N. Vogel. 2002. TLR4, but not TLR2, mediates IFN-β-induced STAT1α/β- dependent gene expression in macrophages. Nat. Immunol. 3: 392-398.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
33
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng, T., G. M. Barton, and R. Medzhitov. 2001. TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2: 835-841.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
34
-
-
11144222174
-
Inhibition of Akt kinase activity by a peptide spanning the βA strand of the proto-oncogene TCL1
-
Hiromura, M., F. Okada, T. Obata, D. Auguin, T. Shibata, C. Roumestand, and M. Noguchi. 2004. Inhibition of Akt kinase activity by a peptide spanning the βA strand of the proto-oncogene TCL1. J. Biol. Chem. 279: 53407-53418.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 53407-53418
-
-
Hiromura, M.1
Okada, F.2
Obata, T.3
Auguin, D.4
Shibata, T.5
Roumestand, C.6
Noguchi, M.7
-
35
-
-
0033534720
-
Monocyte adherence induced by lipopolysaccharide involves CD14, LFA-1, and cytohesin-1: Regulation by Rho and phosphatidylinositol 3-kinase
-
Hmama, Z., K. L. Knutson, P. Herrera-Velit, D. Nandan, and N. E. Reiner. 1999. Monocyte adherence induced by lipopolysaccharide involves CD14, LFA-1, and cytohesin-1: regulation by Rho and phosphatidylinositol 3-kinase. J. Biol. Chem. 274: 1050-1057.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1050-1057
-
-
Hmama, Z.1
Knutson, K.L.2
Herrera-Velit, P.3
Nandan, D.4
Reiner, N.E.5
-
36
-
-
15444365158
-
Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: Regulation by phosphatidylinositol 3-kinase and cytohesin-1
-
Sendide, K., N. E. Reiner, J. S. Lee, S. Bourgoin, A. Talal, and Z. Hmama. 2005. Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1. J. Immunol. 174: 4210-4219. (Pubitemid 40396001)
-
(2005)
Journal of Immunology
, vol.174
, Issue.7
, pp. 4210-4219
-
-
Sendide, K.1
Reiner, N.E.2
Lee, J.S.I.3
Bourgoin, S.4
Talal, A.5
Hmama, Z.6
-
37
-
-
0027398448
-
A subpopulation of Mac-1 (CD11b/ CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen
-
Diamond, M. S., and T. A. Springer. 1993. A subpopulation of Mac-1 (CD11b/ CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120: 545-556.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 545-556
-
-
Diamond, M.S.1
Springer, T.A.2
-
38
-
-
0027530684
-
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands
-
Diamond, M. S., J. Garcia-Aguilar, J. K. Bickford, A. L. Corbi, and T. A. Springer. 1993. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J. Cell Biol. 120: 1031-1043.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 1031-1043
-
-
Diamond, M.S.1
Garcia-Aguilar, J.2
Bickford, J.K.3
Corbi, A.L.4
Springer, T.A.5
-
39
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
40
-
-
0032524335
-
MyD88, an adapter protein involved in interleukin-1 signaling
-
Burns, K., F. Martinon, C. Esslinger, H. Pahl, P. Schneider, J. L. Bodmer, F. Di Marco, L. French, and J. Tschopp. 1998. MyD88, an adapter protein involved in interleukin-1 signaling. J. Biol. Chem. 273: 12203-12209.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12203-12209
-
-
Burns, K.1
Martinon, F.2
Esslinger, C.3
Pahl, H.4
Schneider, P.5
Bodmer, J.L.6
Di Marco, F.7
French, L.8
Tschopp, J.9
-
41
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto, M., S. Sato, H. Hemmi, H. Sanjo, S. Uematsu, T. Kaisho, K. Hoshino, O. Takeuchi, M. Kobayashi, T. Fujita, K. Takeda, and S. Akira. 2002. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420: 324-329.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
Hoshino, K.7
Takeuchi, O.8
Kobayashi, M.9
Fujita, T.10
Takeda, K.11
Akira, S.12
-
42
-
-
33646908228
-
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
-
Kagan, J. C., and R. Medzhitov. 2006. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125: 943-955.
-
(2006)
Cell
, vol.125
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
43
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald, K. A., E. M. Palsson-McDermott, A. G. Bowie, C. A. Jefferies, A. S. Mansell, G. Brady, E. Brint, A. Dunne, P. Gray, M. T. Harte, et al. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413: 78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
-
44
-
-
0345991221
-
TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-β
-
Oshiumi, H., M. Sasai, K. Shida, T. Fujita, M. Matsumoto, and T. Seya. 2003. TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-β. J. Biol. Chem. 278: 49751-49762.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49751-49762
-
-
Oshiumi, H.1
Sasai, M.2
Shida, K.3
Fujita, T.4
Matsumoto, M.5
Seya, T.6
-
45
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
DOI 10.1038/ni986
-
Yamamoto, M., S. Sato, H. Hemmi, S. Uematsu, K. Hoshino, T. Kaisho, O. Takeuchi, K. Takeda, and S. Akira. 2003. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat. Immunol. 4: 1144-1150. (Pubitemid 37428043)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
Takeuchi, O.7
Takeda, K.8
Akira, S.9
-
46
-
-
38349188189
-
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation
-
Yin, H., A. Stojanovic, N. Hay, and X. Du. 2008. The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood 111: 658-665.
-
(2008)
Blood
, vol.111
, pp. 658-665
-
-
Yin, H.1
Stojanovic, A.2
Hay, N.3
Du, X.4
-
47
-
-
0033604585
-
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
-
Kandel, E. S., and N. Hay. 1999. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp. Cell Res. 253: 210-229.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 210-229
-
-
Kandel, E.S.1
Hay, N.2
-
49
-
-
0034122721
-
CR3: A general purpose adhesion-recognition receptor essential for innate immunity
-
Ehlers, M. R. W. 2000. CR3: a general purpose adhesion-recognition receptor essential for innate immunity. Microbes Infect. 2: 289-294.
-
(2000)
Microbes Infect.
, vol.2
, pp. 289-294
-
-
Ehlers, M.R.W.1
-
50
-
-
34247154495
-
Peptidoglycan increases firm adhesion of monocytes under flow conditions and primes monocyte chemotaxis
-
Nijhuis, M. M., G. Pasterkamp, N. I. Sluis, D. P. de Kleijn, J. D. Laman, and L. H. Ulfman. 2007. Peptidoglycan increases firm adhesion of monocytes under flow conditions and primes monocyte chemotaxis. J. Vasc. Res. 44: 214-222.
-
(2007)
J. Vasc. Res.
, vol.44
, pp. 214-222
-
-
Nijhuis, M.M.1
Pasterkamp, G.2
Sluis, N.I.3
De Kleijn, D.P.4
Laman, J.D.5
Ulfman, L.H.6
-
51
-
-
0034577944
-
Toll-like receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway
-
Arbibe, L., J. P. Mira, N. Teusch, L. Kline, M. Guha, N. Mackman, P. J. Godowski, R. J. Ulevitch, and U. G. Knaus. 2000. Toll-like receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway. Nat. Immunol. 1: 533-540.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 533-540
-
-
Arbibe, L.1
Mira, J.P.2
Teusch, N.3
Kline, L.4
Guha, M.5
Mackman, N.6
Godowski, P.J.7
Ulevitch, R.J.8
Knaus, U.G.9
-
52
-
-
0035159327
-
Lipopolysaccharide-induced activation of β2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- Activated protein kinase, and the Rap1 GTPase
-
Schmidt, A., E. Caron, and A. Hall. 2001. Lipopolysaccharide-induced activation of β2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- activated protein kinase, and the Rap1 GTPase. Mol. Cell Biol. 21: 438-448.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 438-448
-
-
Schmidt, A.1
Caron, E.2
Hall, A.3
-
53
-
-
0029870402
-
Rac GTPase interacts specifically with phosphatidylinositol 3-kinase
-
Bokoch, G. M., C. J. Vlahos, Y. Wang, U. G. Knaus, and A. E. Traynor-Kaplan. 1996. Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. Biochem. J. 315: 775-779.
-
(1996)
Biochem. J.
, vol.315
, pp. 775-779
-
-
Bokoch, G.M.1
Vlahos, C.J.2
Wang, Y.3
Knaus, U.G.4
Traynor-Kaplan, A.E.5
-
54
-
-
0035813130
-
Actin cytoskeletal association of cytohesin-1 is regulated by specific phosphorylation of its carboxyl-terminal polybasic domain
-
Dierks, H., J. Kolanus, and W. Kolanus. 2001. Actin cytoskeletal association of cytohesin-1 is regulated by specific phosphorylation of its carboxyl-terminal polybasic domain. J. Biol. Chem. 276: 37472-37481.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37472-37481
-
-
Dierks, H.1
Kolanus, J.2
Kolanus, W.3
-
55
-
-
0035942221
-
Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers
-
Mayer, G., M. Blind, W. Nagel, T. Bohm, T. Knorr, C. L. Jackson, W. Kolanus, and M. Famulok. 2001. Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers. Proc. Natl. Acad. Sci. USA 98: 4961-4965.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4961-4965
-
-
Mayer, G.1
Blind, M.2
Nagel, W.3
Bohm, T.4
Knorr, T.5
Jackson, C.L.6
Kolanus, W.7
Famulok, M.8
-
57
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby, P. 2002. Inflammation in atherosclerosis. Nature 420: 868-874.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
58
-
-
0032037616
-
Macrophage receptors for Mycobacterium tuberculosis
-
Ernst, J. D. 1998. Macrophage receptors for Mycobacterium tuberculosis. Infect. Immun. 66: 1277-1281.
-
(1998)
Infect. Immun.
, vol.66
, pp. 1277-1281
-
-
Ernst, J.D.1
-
59
-
-
58149334966
-
Subversion of innate immunity by periodontopathic bacteria via exploitation of complement receptor- 3
-
Hajishengallis, G., M. Wang, S. Liang, M. A. Shakhatreh, D. James, S. Nishiyama, F. Yoshimura, and D. R. Demuth. 2008. Subversion of innate immunity by periodontopathic bacteria via exploitation of complement receptor- 3. Adv. Exp. Med. Biol. 632: 203-219.
-
(2008)
Adv. Exp. Med. Biol.
, vol.632
, pp. 203-219
-
-
Hajishengallis, G.1
Wang, M.2
Liang, S.3
Shakhatreh, M.A.4
James, D.5
Nishiyama, S.6
Yoshimura, F.7
Demuth, D.R.8
-
60
-
-
0141533034
-
Roles of Rho-family GTPases in cell polarisation and directional migration
-
Fukata, M., M. Nakagawa, and K. Kaibuchi. 2003. Roles of Rho-family GTPases in cell polarisation and directional migration. Curr. Opin. Cell Biol. 15: 590-597.
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 590-597
-
-
Fukata, M.1
Nakagawa, M.2
Kaibuchi, K.3
-
61
-
-
0037374815
-
The role of PI3K in immune cells
-
Koyasu, S. 2003. The role of PI3K in immune cells. Nat. Immunol. 4: 313-319.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 313-319
-
-
Koyasu, S.1
|