Topical antiseptics for the treatment of sore throat block voltage-gated neuronal sodium channels in a local anaesthetic-like manner

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 380, Issue 2, 2009, Pages 161-168

  Buchholz, Vanessa ^a   Leuwer, Martin ^b   Ahrens, Jörg ^a   Foadi, Nilufar ^a   Krampfl, Klaus ^a   Haeseler, Gertrud ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Amylmetacresol; Dichloro benzylalcohol; Hexylresorcinol; Local anaesthetic; Sodium channels; Voltage operated

Indexed keywords

AMYLMETACRESOL; BENZYL ALCOHOL DERIVATIVE; DICHLOROBENZYL ALCOHOL; HEXYLRESORCINOL; LIDOCAINE; META CRESOL; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DEPOLARIZATION; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; LOCAL ANESTHESIA; LOZENGE; MEMBRANE POTENTIAL; SODIUM CURRENT; SORE THROAT;

ANESTHETICS, LOCAL; ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; BENZYL ALCOHOLS; CELL LINE; CRESOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEXYLRESORCINOL; HUMANS; LIDOCAINE; NERVE TISSUE PROTEINS; NEURONS; PHARYNGITIS; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TRANSFECTION;

EID: 67449113541     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-009-0416-x     Document Type: Article

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