High-affinity blockade of voltage-operated skeletal muscle sodium channels by 2,6-dimethyl-4-chlorophenol

European Journal of Anaesthesiology

Volumn 23, Issue 3, 2006, Pages 190-196

  Haeseler, G ^a   Gudehus, S ^a   Bufler, J ^a   Dengler, R ^a   Leuwer, M ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Anaesthetics local, phenol derivatives, lidocaine; Rats; Sodium channels, voltage operated

Indexed keywords

2,6 DIMETHYL 4 CHLOROPHENOL; ALCOHOL DERIVATIVE; HALIDE; PHENOL DERIVATIVE; SODIUM; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IC 50; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; REPOLARIZATION; SKELETAL MUSCLE; SODIUM CURRENT;

ALGORITHMS; ANESTHETICS, INTRAVENOUS; CELL LINE; ELECTROPHYSIOLOGY; HUMANS; ION CHANNEL GATING; MUSCLE, SKELETAL; PATCH-CLAMP TECHNIQUES; PROPOFOL; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TRANSFECTION; XYLENES;

EID: 33344455788     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0265021505002176     Document Type: Article

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