Specificity and Affinity of Lac Repressor for the Auxiliary Operators O2 and O3 Are Explained by the Structures of Their Protein-DNA Complexes

Journal of Molecular Biology

Volumn 390, Issue 3, 2009, Pages 478-489

  Romanuka, Julija ^a   Folkers, Gert E ^a   Biris, Nikolaos ^a   Tishchenko, Evgeny ^b   Wienk, Hans ^a   Bonvin, Alexandre M J J ^a   Kaptein, Robert ^a   Boelens, Rolf ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

lac headpiece; lac operators; NMR; protein DNA recognition

Indexed keywords

GENE PRODUCT; MUTANT PROTEIN; PROTEIN LAC; PROTEIN O2; PROTEIN O3; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; DNA PROTEIN COMPLEX; OPERATOR GENE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DNA BINDING; PROTEIN STABILITY;

EID: 67449102263     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.05.022     Document Type: Article

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