Antioxidant effect of Ajuga iva aqueous extract in streptozotocin-induced diabetic rats

Phytomedicine

Volumn 16, Issue 6-7, 2009, Pages 623-631

  Taleb Senouci, D ^a   Ghomari, H ^a   Krouf, D ^a   Bouderbala, S ^a   Prost, J ^b   Lacaille Dubois, M A ^b   Bouchenak, M ^a  

^a UNIVERSITÉ DES SCIENCES ET DE LA TECHNOLOGIE D ORAN MOHAMED BOUDIAF   (Algeria)

^b UNIVERSITÉ DE BOURGOGNE   (France)

Author keywords

Ajuga iva; Antioxidant status; Diabetic rats; Lamiaceae; Lipid peroxidation

Indexed keywords

AJUGA IVA EXTRACT; CARBONYL DERIVATIVE; CAROTENOID; CASEIN; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; NITRIC OXIDE; PLANT EXTRACT; STREPTOZOCIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROLOX C; UNCLASSIFIED DRUG;

AJUVA IVA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BRAIN; COMPARATIVE STUDY; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ERYTHROCYTE; HEART; IN VITRO STUDY; LIPID PEROXIDATION; LIVER; MALE; MEDICINAL PLANT; MUSCLE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; BODY WEIGHT; CAROTENOIDS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INSULIN; LIPID PEROXIDATION; LIPIDS; MALE; NITRIC OXIDE; ORGAN SIZE; PLANT EXTRACTS; RATS; RATS, WISTAR; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

AJUGA IVA; LAMIACEAE; RATTUS;

EID: 67349278810     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.12.004     Document Type: Article

References (50)

1. Aebi H. Catalase. In: Berg Meyer H. (Ed). Methods of Enzymatic Analysis. second ed (1974), Verlag chemie, Weinheim, Germany 673-684
2. Ananthan R., Latha M., Ramkumar K.M., Pari L., Baskar C., and Narmatha Bai V. Modulatory effect of Gymnema montanum leaf extract on alloxan-induced oxidative stress in Wistar rats. J. Nutr. 20 (2004) 280-285
3. Badami S., Gupta M.K., and Suresh B. Antioxidant activity of the ethanolic extract of Striga orobanchioides. J. Ethnopharmacol. 85 (2003) 227-230
4. Beckman J.S., and Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am. J. Physiol. 271 (1996) 424-437
5. Bhor V.M., Raghuram N., and Sivakami S. Oxidative damage and altered antioxidant enzymes activities in the intestine of streptozotocin-induced diabetic rats. Int. J. Biochem. Cell. Biol. 36 (2004) 89-97
6. Blache D., and Prost M. Free radical attack: biological test for human resistance capability. In: Ponnamperuma C., and Gehrke C.W. (Eds). A Lunar-Based Chemical Analysis Laboratory (1992), A. Deepak, Hampton 82-98
7. Bortolotti G.R., Negro J.J., Tella J.L., Marehant T.A., and Bird D.M. Sexual dichromatism in birds independent of diet, parasites and androgens. Proc. R. Soc. London 263 (1996) 1171-1176
8. Chenni A., Ait yahia D., Boukortt F.O., Prost J., Lacaille-Dubois M.A., and Bouchenak M. Effect of aqueous extract of Ajuga iva supplementation on plasma lipid profile and tissue antioxidant status in rats fed a high-cholesterol diet. J. Ethnopharmacol. 109 (2007) 207-213
9. Chevion M., Berenshtein E., and Stadtman E.R. Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic. Res. 33 Suppl. (2000) S99-S108
10. Cortas N., and Wakid N. Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method. Clin. Chem. 36 (1990) 1440-1443
11. Council of European Communities, 1987. Council instructions about the protection of living animals used in scientific investigations. Official J. L358 of 18-12-1986; Corrigendum Official J. L117 of 05-05-1987.
12. Eddouks M., Lemhadri A., Zeggwagh N.A., and Michel J.B. Potent hypoglycaemic activity of the aqueous extract of Chamaemelum nobile in normal and streptozotocin-induced diabetic rats. Diabetes Res. Clin. Pract. 67 (2005) 189-195
13. El-Hilaly J., and Lyoussi B. Hypoglycemic effect of the lyophilized aqueous extract of Ajuga iva in normal and streptozotocin diabetic rats. J. Ethnopharmacol. 80 (2002) 109-113
14. El-Hilaly J., Lyoussi B., Wibo M., and Morel N. Vasorelaxant effect of the aqueous extract of Ajuga iva in rat aorta. J. Ethnopharmacol. 93 (2004) 69-74
15. El-Hilaly J., Tahraoui A., Israili Z.H., and Lyoussi B. Hypolipidemic effects of acute and sub-chronic administration of an aqueous extract of Ajuga iva L. whole plant in normal and diabetic rats. J. Ethnopharmacol. 105 (2006) 441-448
16. Elstner E.F., Youngman R.J., and Obwald W. Superoxide dismutase. In: Berg Meyer H. (Ed). Methods of Enzymatic Analysis (1983), Verlag Chemie, Weinheim, Germany 293-302
17. Fabricant D.S., and Farnsworth N.R. The value of plants used in traditional medicine for drug discovery. Environ. Health Persp. 109 (2001) 69-75
18. Frei B., and Higdon J.V. Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J. Nutr. 133 (2003) 3275-3284
19. Genet S., Kale R.K., and Baquer N.Z. Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of vanadate and fenugreek (Trigonella foenum graecum). Mol. Cell. Biochem. 236 (2002) 7-12
20. Ghedira K., Chemli R., Richard B., Zeches M., and Le Men-Olivier L. Study of the traditional pharmacopeia of Tunisia. Plant. Méd. Phytothér. 25 (1991) 100-111
21. Goldberg D.M., and Spooner R.J. Glutathione reductase. In: Berg Meyer H. (Ed). Methods of Enzymatic Analysis. second ed (1992), Verlag chemie, Weinheim, Germany 258-265
22. Houghton P.J., and Raman A. Laboratory Handbook for the Fractionation of Natural Extracts. first ed (1998), ITP, London
23. Jimenz J., Risco S., Ruiz T., and Zaruelo A. Hypoglyceamic activity of Salvia lavandulifolia. Planta Med. 4 (1986) 260-262
24. Kakkar R., Kalra J., Mantha S.V., and Prasad K. Lipid peroxidation and activity of antioxidant enzymes in diabetic rats. Mol. Cell. Biochem. 151 (1995) 113-119
25. Kakkar R., Mantha S.V., Radhi. J., Prasad K., and Kalra J. Antioxidant defense system in diabetic kidney: a time course study. Life. Sci. 60 (1997) 667-679
26. Larkins N., and Wynn S. Pharmacognosy: phytomedicines and their mechanisms. Vet. Clin. North Am. Small Anim. Pract. 34 (2004) 291-327
27. Leclercq B., Jaimes E.A., and Raij L. Nitric oxide synthase and hypertension. Curr. Opin. Nephrol. Hyperten. 11 (2002) 185-189
28. Lemhadri A., Zeggwagh N.A., Maghrani M., Jouad H., and Eddouks M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J. Ethnopharmacol. 92 (2004) 251-256
29. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., Ahn B.W., Shaltiel S., and Stadtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 186 (1990) 464-478
30. Levy U., Zaltzber H., Ben-Amotz A., Kanter Y., and Aviram M. β-Carotene affects antioxidant status in non-insulin dependent diabetes mellitus. Pathophysiology 6 (1999) 157-161
31. Limaye P.V., Raghuram N., and Sivakami S. Oxidative stress and gene expression of antioxidant enzymes in the renal cortex of streptozotocin-induced diabetic rats. Mol. Cell. Biochem. 243 (2003) 147-152
32. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
33. Maghrani M., Michel J.B., and Eddouks M. Hypoglycaemic activity of Retama raetam in rats. Phytother. Res. 19 (2005) 125-128
34. McLennan S.V., Heffernan S., Wright L., Rae C., Fisher E., Yue D.K., and Turtle J.R. Changes in hepatic glutathione metabolism in diabetes. Diabetes 40 (1991) 344-348
35. Miyake Y., Yamamoto K., Tsujihara N., and Osawa T. Protective effects of lemon flavonoids on oxidative stress in diabetic rats. Lipids 33 (1998) 689-695
36. Nogueira F.N., Carvalho A.M., Yamaguti P.M., and Nicolau J. Antioxidants parameters and lipid peroxidation in salivary glands of streptozotocin-induced diabetic rats. Clin. Chem. Acta 353 (2005) 133-139
37. Paglia D.E., and Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70 (1967) 158-169
38. Panneerselvam S.R., and Govindasamy S. Effect of sodium molybdate on the status of lipid peroxidation and antioxidant systems in alloxan-induced diabetic rats. Clin. Chem. Acta 345 (2004) 93-98
39. Pari L., and Venkateswaran S. Protective effect of Coccinia indica on changes in the fatty acid composition in streptozotocin induced diabetic rats. Pharmazie 58 (2003) 409-412
40. Pari L., and Latha M. Effect of Scoparia dulcis (Sweet Broomweed) plant extract on plasma antioxidants in streptozotocin-induced experimental diabetes in male albino Wistar rats. Pharmazie 59 (2004) 557-560
41. Ramesh B., and Pugalendi K.V. Antioxidant role of Umbelliferone in STZ-diabetic rats. Life Sci. 79 (2006) 306-310
42. Sabu M.C., and Kuttan R. Antidiabetic activity of Aegle marmelos and its relationship with its antioxidant properties. Ind. J. Physiol. Pharmacol. 48 (2004) 81-88
43. Satheesh M.A., and Pari L. Antioxidant effect of Boerhavia diffusa L. in tissues of alloxan induced diabetic rats. Ind. J. Exp. Biol. 42 (2004) 989-992
44. Saxena A.K., Srivastava P., Kale R.K., and Baquer N.Z. Impaired antioxidant status in diabetic rat liver: effect of vanadate. Biochem. Pharmacol. 45 3 (1993) 539-542
45. Soto C., Recoba R., Barron H., Alvarez C., and Favari L. Sylimarin increases antioxidant enzymes in alloxan-induced diabetes in rat pancreas. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 136 (2003) 205-212
46. Sudheesh S., and Vijayalakshmi N.R. Flavonoids from Punic granatum - potential antiperoxidative agents. Fitoterapia 76 (2005) 181-186
47. Syrov V.N., Khushbaktova Z.A., Abzalova M.Kh., and Sultanov M.B. Hypolipidemic and antiatherosclerotic properties of phytoecdysteroids. Dokl. Akad. Nauk USSR 9 (1983) 44-45
48. Tenner Jr. T.E., Zhang X.J., and Lombardini J.B. Hypoglycemic effects of taurine in the alloxan-treated rabbit, a model for type 1 diabetes. Adv. Exp. Med. Biol. 526 (2003) 97-104
49. Vijayakumar M., Govindarajan R., Rao G.M.M., Rao C.V., Shirwaikar A., Mehrotra S., and Pushpangadan P. Action of Hygrophila auriculata against streptozotocin-induced oxidative stress. J. Ethnopharmacol. 104 (2006) 356-361
50. Wagner H., and Lacaille-Dubois M.A. Recent pharmacological results on bioflavonoids. In: Antus S., Gabor M., and Vetschera K. (Eds). Flavonoids and Bioflavonoids (1995), Akademiai Kiado, Budapest 53-72