β-Carotene affects antioxidant status in non-insulin-dependent diabetes mellitus

Pathophysiology

Volumn 6, Issue 3, 1999, Pages 157-161

  Levy, Yishai ^a   Zaltzberg, Haya ^a   Ben Amotz, Ami ^a   Kanter, Yoram ^a   Aviram, Michael ^a  

^a RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Carotene; Antioxidants; Glutathione redox cycle; Non insulin dependent diabetes mellitus (NIDDM)

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ADULT; AGE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SEX; VASCULAR DISEASE;

EID: 0032756560     PISSN: 09284680     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-4680(99)00013-9     Document Type: Article

References (32)

1. Kannel W.B., McGee D.L. Diabetes and cardiovascular risk factors: the Framingham study. Circulation. 59:1979;8-13.
2. Lyons T.J. Glycation and oxidation: a role in the pathogenesis of atherosclerosis. Am. J. Cardiol. 71:1993;26B-31B.
3. Steinberg D. Antioxidants and atherosclerosis. Circulation. 84:1991;1420-1425.
4. Bierhaus A. et al. Advanced glycation end product-induced activation of NF-κB is suppressed by α-lipoic acid in cultured endothelial cells. Diabetes. 46:1997;1481-1490.
5. Gugliano D., Ceriello A. Oxidative stress and diabetic vascular complications. Diabetes Care. 19:1996;257-267.
6. Godin D.V. et al. Antioxidant enzyme alterations in experimental and clinical diabetes. Mol. Cell Biochem. 84:1988;223-231.
7. Maxwell S.R.J. et al. Antioxidant status in patients with uncomplicated insulin-dependent and non-insulin-dependent diabetes mellitus. Eur. J. Clin. Invest. 27:1997;484-490.
8. Reaven P.D. et al. Effect of vitamin E on susceptibility of LDL and LDL subfractions to oxidation and on protein glycosylation in NIDDM. Diabetes Care. 18:1995;807-816.
9. Babiy A.V. et al. Increased oxidizability of plasma lipoproteins in diabetic patients can be decreased by probucol therapy and is not due to glycation. Biochem. Pharma. 43:1992;995-1000.
10. Packer L. Antioxidant properties of lipoic acid as a biological antioxidant. Free Radic. Biol. Med. 19:1995;227-250.
11. Packer L. The role of anti-oxidative treatment in diabetes mellitus. Diabetologia. 36:1993;1212-1213.
12. Krinsky N.I. Antioxidant functions of carotenoids. Free Radic. Biol. Med. 7:1989;617-635.
13. Reaven P.D. et al. Effect of dietary antioxidant combinations in humans: protection of LDL by vitamin E, but not by β-carotene. Arterioscler. Thromb. 13:1993;590-600.
14. Levy Y. et al. Effect of dietary supplementation of different β-carotene isomers on lipoprotein oxidative modification. J. Nutr. Med. 5:1995;13-22.
15. Levy Y. et al. The effect of dietary supplementation of β-carotene on human monocyte-macrophage-mediated oxidation of low density lipoprotein. Isr. J. Med. Sci. 32:1996;473-478.
16. Ben-Amotz A., Levy Y. Bioavailability of a natural isomer mixture compared with synthetic all-trans β-carotene in human serum. Am. J. Clin. Nutr. 63:1996;729-734.
17. Levin G., Mokady S. Antioxidant activity of 9-cis compared to all-trans β-carotene in vitro. Free Radic. Biol. Med. 17:1994;77-82.
18. Levin G. et al. Antiperoxidative effect of 9-cis β-carotene compared with that of the all-trans isomer. Nutr. Cancer. 27:1997;293-297.
19. Omenn G.S. et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med. 334:1996;1150-1155.
20. S.T. Mayne, et al., Carotene and lung cancer promotion in heavy smokers - a plausible relationship?, J. Natl. Cancer Inst. 88 (1996) 1513-1515.
21. Palozza P., Krinsky N.I. Carotene and α-tocopherol are synergistic antioxidants. Arch. Biochem. Biophys. 297:1992;184-187.
22. Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 27:1969;502-522.
23. Kokatnur V.R., Jelling M. Iodometric determination of peroxygen in organic compounds. Am. Chem. Soc. 63:1941;1432-1433.
24. Beutler E. Effect of flavin compounds on glutathione reductase activity: in vivo and in vitro studies. J. Clin. Invest. 48:1969;1957-1966.
25. Habig W.H. et al. Glutathione-s-transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:1974;7130-7139.
26. Baynes J.W. Role of oxidative stress in development of complication in diabetes. Diabetes. 40:1991;405-412.
27. Bode A.M. et al. Enzymatic basis for altered ascorbic acid and dehydroascorbic acid levels in diabetes. Biochem. Biophys. Res. Commun. 19:1993;257-1353.
28. Slater T.F. Free radical mechanism and tissue injury. Biochem. J. 222:1984;1-15.
29. Truscott T.G. Beta-carotene and disease: a suggested pro-oxidant and anti-oxidant mechanism and speculations concerning its role in cigarette smoking. J. Photochem. Photobiol. B Biol. 35:1996;233-235.
30. Hokkaido I.Z. Glutathione metabolism in erythrocytes from patients with diabetes mellitus. Hokkaido J. Med. Sci. 66:1991;29-40.
31. van Poppel G. et al. Markers for cytogenetic damage in smokers: associations with plasma antioxidants and glutathione-s-transferase mu. Cancer Epidol. Biomarkers Prev. 2:1993;441-447.
32. Challem J.J. Re: Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial (Letter). J. Natl. Cancer Inst. 89:1997;325.