Hypoglycaemic activity of Retama raetam in rats

Phytotherapy Research

Volumn 19, Issue 2, 2005, Pages 125-128

  Maghrani, Mhamed ^a   Michel, Jean Baptiste ^b   Eddouks, Mohamed ^a,c  

^a MOULAY ISMAIL UNIVERSITY   (Morocco)

^b BICHAT HOSPITAL   (France)

^c NONE   (Morocco)

Author keywords

Aqueous extract; Glycosuria; Hypoglycaemic effect; Insulin concentrations; Plasma glucose; Retama raetam; Streptozotocin rats

Indexed keywords

ANTIDIABETIC AGENT; GLUCOSE; INSULIN; PLANT EXTRACT; RETAMA RAETAM EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSURIA; INSULIN BLOOD LEVEL; KIDNEY TUBULE ABSORPTION; NONHUMAN; RAT;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; FABACEAE; HYPOGLYCEMIC AGENTS; INFUSIONS, INTRAVENOUS; INSULIN; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; STREPTOZOCIN;

RETAMA RAETAM;

EID: 18444386164     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1627     Document Type: Article

References (25)

1. Ajgaonkar SS. 1979. Herbal drugs in the treatment of diabetes, a review. IDF Bull 24: 10-17.
2. Alarcon-Aguilara J, Roman-Ramos, R, Perez-Gutierrez S, Aguilar-Contreras A, Contreras-Weber CC, Flores-Saenz JL. 1998. Study of the antihyperglycaemic effect of plants used as antidiabetics. J Ethnopharmacol 61: 101-110.
3. Boulos L. 1999. Flora of Egypt, vol. 1: Azollacea-Oxalidaceae. AI-Hadara: Cairo, Egypt, 258-259.
4. Burcelin R, Eddouks M, Maury J, Kande J, Assan R, Girard J. 1995. Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats. Diabetologia 38: 283-290.
5. Cheeseman C. 1992. Role of intestinal basolateral membrane in absorption of nutrients. Am J Physiol 32: R482-R488.
6. Domingez JH, Camp K, Maianu L, Garvey WT. 1992. Glucose transporters of rat proximal tubule: differential expression and subcellular distribution. Am J Physiol 262: F807-F812.
7. Eddouks M, Maghrani M, Lemhadri A, Ouahidi M-L, Jouad H. 2002. Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). J Ethnopharmacol 82: 97-103.
8. El Bahri L, Djegham M, Bellil H. 1999. Retama raetam W: a poisonous plant of North Africa. Vet Hum Toxicol 41: 33-35.
9. Farnsworth NR. 1980. The development of pharmacological and chemical research for application of traditional medicine in developing countries. J Ethnopharmacol 2: 173-181.
10. Ferraris RP, Diamond JM. 1989. Specific regulation of intestinal nutrient transporters by their dietary substrates. Annu Rev Physiol 51: 125-141.
11. Gerich JE. 1988. Glucose counterregulation and its impact on diabetes mellitus. Diabetes 37: 1608-1617.
12. Gupta MP, Solis NG, Avella ME, Sanchez G. 1984. Hypoglycemic activity of Neurolena lobata (L.). J Ethnopharmacol 10: 323-327.
13. +/glucose cotransporter. Nature 330: 379-381.
14. Jouad H, Eddouks M, Lacaille-Dubois MA, Lyoussi B. 2000. Hypoglycaemic effect of the water extract of Spergularia purpurea in normal and streptozotocin-induced diabetic rats. J Ethnopharmacol 71: 169-177.
15. Jouad H, Haloui M, Rhiouani H, El Hilaly J, Eddouks M. 2001. Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez-Boulmane). J Ethnopharmacol 77: 175-182.
16. Karawya, SM, Abdel Wahab SM, El-Olemy MM, Farag M. 1984. Diphenylamine, an antihyperglycemic agent from onion and tea. J Nat Prod 47: 775-780.
17. Kassem M, Mosharrafa SA, Saleh NA, Abdel-Wahab SM. 2000. Two flavonoids from Retama raetam. Fitoterapia 71: 649-654.
18. Kinne R. 1979. Metabolic correlates of tubular transport. In Membrane Transport in Biology, Giebischg, Tosteson DC, Ussing HH. (eds). Springer-Verlag: Berlin, 529-562.
19. Levy E, Bendayan M. 1991. Lipoprotein lipase in experimental diabetic rats: beneficial effect of vanadate treatment. Diabete Metabol 17: 44-48.
20. Maddox J, Gennari JF. 1987. The early proximal tubule: a high capacity delivery-response reabsorptive site. Am J Physiol 252: F573-F584.
21. Mittler R, Merquiol E, Hallak-Herr E, Rachmilevitch S, Kaplan A, Cohen M. 2001. Living under a 'dormant' canopy: a molecular acclimation mechanism of the desert plant Retama raetam. Plant J 25: 407-416.
22. +/glucose cotransporter: Voltage-clamp studies. J Membr Biol 125: 49-62.
23. Sakhrani LM, Badie-Dezfooly B, Trizna W, et al. 1984. Transport and metabolism of glucose by renal proximal tubular cells in primary culture. Am J Physiol 246: F757-F764.
24. Torres IC, Suarez JC. 1980. A preliminary study of hypoglycemic activity of Luthrum salicaria. J Nat Prod 43: 559-563.
25. WHO. 1978. Resolution: Drug Policies and Management: Medicinal Plants. WHO: Genera, WHO document WHA31.33.