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Volumn 55, Issue 2, 2009, Pages 175-184

Carotenoids and carotenogenic genes in Podospora anserina: Engineering of the carotenoid composition extends the life span of the mycelium

Author keywords

Ageing protection; al Genes; Carotenoid biosynthesis; Metabolic engineering; Neurosporaxanthin

Indexed keywords

4' APO GAMMA CAROTENE 4' AL; 7,8 DIHYDRO BETA CAROTENE; BETA CAROTENE; BETA ZEACAROTENE; CAROTENOID; FUNGAL PROTEIN; GAMMA CAROTENE; LYCOPENE; NEUROSPORAXANTHIN; NEUROSPORIN; PHYTOENE; TORULENE; UNCLASSIFIED DRUG;

EID: 67349270292     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00294-009-0235-0     Document Type: Review
Times cited : (28)

References (47)
  • 1
    • 0013828963 scopus 로고
    • Fungal carotenoids. II. The structure of the carotenoid acid neurosporaxanthin
    • Aasen AJ, Jensen SL (1965) Fungal carotenoids. II. The structure of the carotenoid acid neurosporaxanthin. Acta Chem Scand 19:1843-1853
    • (1965) Acta Chem Scand , vol.19 , pp. 1843-1853
    • Aasen, A.J.1    Jensen, S.L.2
  • 2
    • 12944284362 scopus 로고
    • Recherches chimotaxinomiques sur les champignons Fungal carotenoids. III-Nouveaux carotenoides, notamment sous forme d'esters tertiaires, isoles de Plectania coccinea (Scop. Ex Fr) Fuck
    • Arpin N, Liaaen-Jensen S (1967a) Recherches chimotaxinomiques sur les champignons Fungal carotenoids. III-Nouveaux carotenoides, notamment sous forme d'esters tertiaires, isoles de Plectania coccinea (Scop. Ex Fr) Fuck. Phytochem 6:995-1005
    • (1967) Phytochem , vol.6 , pp. 995-1005
    • Arpin, N.1    Liaaen-Jensen, S.2
  • 3
    • 56249117021 scopus 로고
    • Recherches chimiotaxinomiques sur le champignons. Sur la présence de l'ester méthylique de la torularhodine chez Cookeina sulcipes
    • Arpin N, Liaaen-Jensen S (1967b) Recherches chimiotaxinomiques sur le champignons. Sur la présence de l'ester méthylique de la torularhodine chez Cookeina sulcipes. C.R. Acad Sci Paris 265:1083-1085
    • (1967) C.R. Acad Sci Paris , vol.265 , pp. 1083-1085
    • Arpin, N.1    Liaaen-Jensen, S.2
  • 5
    • 0001500756 scopus 로고
    • Terpenoid biosynthesis in cell extracts of wild-type and mutant strains of Gibberella fujikuroi
    • Avalos J, Mackenzie A, Nelki DS, Bramley PM (1988) Terpenoid biosynthesis in cell extracts of wild-type and mutant strains of Gibberella fujikuroi. Biochim Biophys Acta 966:257-265
    • (1988) Biochim Biophys Acta , vol.966 , pp. 257-265
    • Avalos, J.1    Mackenzie, A.2    Nelki, D.S.3    Bramley, P.M.4
  • 6
    • 0035140843 scopus 로고    scopus 로고
    • Molecular control of copper homeostasis in filamentous fungi: Increased expression of a metallothionein gene during aging of Podospora anserina
    • Averbeck NB, Borghouts C, Hamann A, Specke V, Osiewacz HD (2001) Molecular control of copper homeostasis in filamentous fungi: Increased expression of a metallothionein gene during aging of Podospora anserina. Mol Gen Genet 264:604-612
    • (2001) Mol Gen Genet , vol.264 , pp. 604-612
    • Averbeck, N.B.1    Borghouts, C.2    Hamann, A.3    Specke, V.4    Osiewacz, H.D.5
  • 7
    • 41149168218 scopus 로고    scopus 로고
    • The effects of vitamin supplementation on Drosophila life span under normoxia and under oxidative stress
    • Bahadorani S, Bahadorani P, Phillips JP, Hilliker AJ (2008) The effects of vitamin supplementation on Drosophila life span under normoxia and under oxidative stress. J Gerontol A Biol Sci Med Sci 63:35-42
    • (2008) J Gerontol A Biol Sci Med Sci , vol.63 , pp. 35-42
    • Bahadorani, S.1    Bahadorani, P.2    Phillips, J.P.3    Hilliker, A.J.4
  • 8
    • 0017289705 scopus 로고
    • Inactivation of carotenoid-producing and albino strains of Neurospora crassa by visible light, black light and ultraviolet radiation
    • Blanc PL, Tuveson RW, Sargent ML (1976) Inactivation of carotenoid-producing and albino strains of Neurospora crassa by visible light, black light and ultraviolet radiation. J Bacteriol 125:616-625
    • (1976) J Bacteriol , vol.125 , pp. 616-625
    • Blanc, P.L.1    Tuveson, R.W.2    Sargent, M.L.3
  • 9
    • 0030996054 scopus 로고    scopus 로고
    • XcmI-Containing vector for direct cloning of PCR products
    • Borovkov AY, Rivkin MI (1997) XcmI-Containing vector for direct cloning of PCR products. Biotechniques 22:812-814
    • (1997) Biotechniques , vol.22 , pp. 812-814
    • Borovkov, A.Y.1    Rivkin, M.I.2
  • 10
    • 0035976252 scopus 로고    scopus 로고
    • 30-bonded stationary phase of mono hydroxycarotenoids with variable chain length or degree of desaturation and of lycopene isomers synthesized by different carotene desaturases
    • 30-bonded stationary phase of mono hydroxycarotenoids with variable chain length or degree of desaturation and of lycopene isomers synthesized by different carotene desaturases. J Chromatogr A 936:59-69
    • (2001) J Chromatogr A , vol.936 , pp. 59-69
    • Breitenbach, J.1    Braun, G.2    Steiger, S.3    Sandmann, G.4
  • 11
    • 0029598850 scopus 로고
    • Structure and properties of carotenoids in relation to function
    • Britton G (1995) Structure and properties of carotenoids in relation to function. FASEB J 9:1551-1558
    • (1995) FASEB J , vol.9 , pp. 1551-1558
    • Britton, G.1
  • 12
    • 35649013178 scopus 로고    scopus 로고
    • Carotenoid profiles of yeasts belonging to the genera Rhodotorula, Rhodosporidium, Sporobolomyces and Sporidiobolus
    • Buzzini P, Inoocenti M, Turchetti B, Libkind D, van Broock M, Mulinacci N (2007) Carotenoid profiles of yeasts belonging to the genera Rhodotorula, Rhodosporidium, Sporobolomyces and Sporidiobolus. Can J Microbiol 53:1024-1031
    • (2007) Can J Microbiol , vol.53 , pp. 1024-1031
    • Buzzini, P.1    Inoocenti, M.2    Turchetti, B.3    Libkind, D.4    van Broock, M.5    Mulinacci, N.6
  • 15
    • 0000912663 scopus 로고
    • Podospora anserina
    • In: King RC (ed) Plenum Press, New York
    • Esser K (1974) Podospora anserina. In: King RC (ed) Handbook of genetics. Plenum Press, New York, pp 531-551
    • (1974) Handbook of Genetics , pp. 531-551
    • Esser, K.1
  • 16
    • 49249123034 scopus 로고    scopus 로고
    • The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway
    • Estrada AF, Youssar L, Scherzinger D, Al-Babili S, Avalos J (2008) The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway. Mol Microbiol 69:1207-1220
    • (2008) Mol Microbiol , vol.69 , pp. 1207-1220
    • Estrada, A.F.1    Youssar, L.2    Scherzinger, D.3    Al-Babili, S.4    Avalos, J.5
  • 18
    • 77049308856 scopus 로고
    • A theory based on free radical and radiation chemistry
    • Harman D (1956) A theory based on free radical and radiation chemistry. J Gerontol 11:298-300
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 19
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D (1972) The biologic clock: The mitochondria? J Am Geriatr Soc 20:145-147
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 20
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • Harman D (1992) Free radical theory of aging. Mutat Res 275:257-266
    • (1992) Mutat Res , vol.275 , pp. 257-266
    • Harman, D.1
  • 21
    • 0033793856 scopus 로고    scopus 로고
    • A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa
    • Hausmann A, Sandmann G (2000) A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa. Fungal Genet Biol 30:147-153
    • (2000) Fungal Genet Biol , vol.30 , pp. 147-153
    • Hausmann, A.1    Sandmann, G.2
  • 22
    • 34548812835 scopus 로고    scopus 로고
    • Intermediates in the oxidative pathway from torulene to torularhodin in the red yeasts Cystofilobasidium infirmominiatum and C. capitatum (Heterobasidiomycetes, Fungi)
    • Herz S, Weber RWS, Anke H, Mucci A, Davoli P (2007) Intermediates in the oxidative pathway from torulene to torularhodin in the red yeasts Cystofilobasidium infirmominiatum and C. capitatum (Heterobasidiomycetes, Fungi). Phytochem 68:2503-2511
    • (2007) Phytochem , vol.68 , pp. 2503-2511
    • Herz, S.1    Weber, R.W.S.2    Anke, H.3    Mucci, A.4    Davoli, P.5
  • 23
    • 33745595856 scopus 로고    scopus 로고
    • Mitochondrial metabolism and aging in the filamentous fungus Podospora anserina
    • Lorin S, Dufour E, Sainsard-Chanet A (2006) Mitochondrial metabolism and aging in the filamentous fungus Podospora anserina. Biochim Biophys Acta 1757:604-610
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 604-610
    • Lorin, S.1    Dufour, E.2    Sainsard-Chanet, A.3
  • 24
    • 0025630190 scopus 로고
    • Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli
    • Misawa N, Nakagawa M, Kobayashi K, Yamano S, Izawa Y, Nakamura K, Harashima K (1990) Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli. J Bacteriol 172:6704-6712
    • (1990) J Bacteriol , vol.172 , pp. 6704-6712
    • Misawa, N.1    Nakagawa, M.2    Kobayashi, K.3    Yamano, S.4    Izawa, Y.5    Nakamura, K.6    Harashima, K.7
  • 25
    • 0028817748 scopus 로고
    • Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level
    • Misawa N, Satomi Y, Kondo K, Yokoyama A, Kajiwara S, Saito T, Ohtani T, Miki W (1995) Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level. J Bacteriol 177:6575-6584
    • (1995) J Bacteriol , vol.177 , pp. 6575-6584
    • Misawa, N.1    Satomi, Y.2    Kondo, K.3    Yokoyama, A.4    Kajiwara, S.5    Saito, T.6    Ohtani, T.7    Miki, W.8
  • 26
    • 0031980175 scopus 로고    scopus 로고
    • Production of the carotenoids lycopene, beta-carotene, and astaxanthin in the food yeast Candida utilis
    • Miura Y, Kondo K, Saito T, Shimada H, Fraser PD, Misawa N (1998) Production of the carotenoids lycopene, beta-carotene, and astaxanthin in the food yeast Candida utilis. Appl Environ Microbiol 64:1226-1229
    • (1998) Appl Environ Microbiol , vol.64 , pp. 1226-1229
    • Miura, Y.1    Kondo, K.2    Saito, T.3    Shimada, H.4    Fraser, P.D.5    Misawa, N.6
  • 27
    • 32444444375 scopus 로고    scopus 로고
    • Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a beta-carotene 3-hydroxylase/4-ketolase
    • Ojima K, Breitenbach J, Visser H, Setoguchi Y, Tabata K, Hoshino T, van den Berg J, Sandmann G (2006) Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a beta-carotene 3-hydroxylase/4-ketolase. Mol Genet Genomics 275:148-158
    • (2006) Mol Genet Genomics , vol.275 , pp. 148-158
    • Ojima, K.1    Breitenbach, J.2    Visser, H.3    Setoguchi, Y.4    Tabata, K.5    Hoshino, T.6    van den Berg, J.7    Sandmann, G.8
  • 28
    • 0037029072 scopus 로고    scopus 로고
    • Mitochondrial functions and aging
    • Osiewacz HD (2002) Mitochondrial functions and aging. Gene 286:65-71
    • (2002) Gene , vol.286 , pp. 65-71
    • Osiewacz, H.D.1
  • 29
    • 0025818937 scopus 로고
    • Integrative transformation of the ascomycete Podospora anserina: Identification of the mating-type locus on chromosome VII of electrophoretically separated chromosomes
    • Osiewacz HD, Skaletz A, Esser K (1991) Integrative transformation of the ascomycete Podospora anserina: Identification of the mating-type locus on chromosome VII of electrophoretically separated chromosomes. Appl Microbiol Biotechnol 35:38-45
    • (1991) Appl Microbiol Biotechnol , vol.35 , pp. 38-45
    • Osiewacz, H.D.1    Skaletz, A.2    Esser, K.3
  • 30
    • 0003105798 scopus 로고
    • Blue light control of pigment biosynthesis
    • In: Senger H (ed) l, CRC Press
    • Rau W, Schrott EL (1987) Blue light control of pigment biosynthesis. In: Senger H (ed) Blue light responses. l, CRC Press, pp 43-63
    • (1987) Blue Light Responses , pp. 43-63
    • Rau, W.1    Schrott, E.L.2
  • 31
    • 35248846478 scopus 로고    scopus 로고
    • Identification of the gene responsible for torulene cleavage in the Neurospora carotenoid pathway
    • Saelices L, Youssar L, Holdermann I, Al-Babili S, Avalos J (2007) Identification of the gene responsible for torulene cleavage in the Neurospora carotenoid pathway. Mol Genet Genomics 278:527-537
    • (2007) Mol Genet Genomics , vol.278 , pp. 527-537
    • Saelices, L.1    Youssar, L.2    Holdermann, I.3    Al-Babili, S.4    Avalos, J.5
  • 32
    • 0000305847 scopus 로고
    • Development of engineered stationary phases for the separation of carotenoid isomers
    • Sander LC, Sharpless KE, Craft NE, Wise SA (1994) Development of engineered stationary phases for the separation of carotenoid isomers. Anal Chem 66:1667-1674
    • (1994) Anal Chem , vol.66 , pp. 1667-1674
    • Sander, L.C.1    Sharpless, K.E.2    Craft, N.E.3    Wise, S.A.4
  • 33
    • 0036901989 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of carotenoids in a heterologous host: A powerful approach for the biosynthesis of novel structures
    • Sandmann G (2002) Combinatorial biosynthesis of carotenoids in a heterologous host: A powerful approach for the biosynthesis of novel structures. Chembiochem 3:629-635
    • (2002) Chembiochem , vol.3 , pp. 629-635
    • Sandmann, G.1
  • 35
    • 33748471772 scopus 로고    scopus 로고
    • The biotechnological potential of the al-2 gene from Neurospra crassa for the production of monocyclic keto hydroxy carotenoids
    • Sandmann G, Zhu C, Krubasik P, Fraser PD (2006) The biotechnological potential of the al-2 gene from Neurospra crassa for the production of monocyclic keto hydroxy carotenoids. Biochim Biophys Acta 1761:1085-1092
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 1085-1092
    • Sandmann, G.1    Zhu, C.2    Krubasik, P.3    Fraser, P.D.4
  • 36
    • 56249130382 scopus 로고    scopus 로고
    • 35-apocarotenoids in the yellow mutant Neurospora crassa YLO
    • 35-apocarotenoids in the yellow mutant Neurospora crassa YLO. Phytochem 69:2885-2890
    • (2008) Phytochem , vol.69 , pp. 2885-2890
    • Sandmann, G.1    Takaichi, S.2    Fraser, P.D.3
  • 37
    • 2942737067 scopus 로고    scopus 로고
    • Production of phytoene, a carotenoid, and induction of connexin 26 in transgenic mice carrying the phytoene synthase gene crtB
    • Satomi Y, Misawa N, Maoka T, Nishino H (2004) Production of phytoene, a carotenoid, and induction of connexin 26 in transgenic mice carrying the phytoene synthase gene crtB. Biochem Biophys Res Commun 320:398-401
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 398-401
    • Satomi, Y.1    Misawa, N.2    Maoka, T.3    Nishino, H.4
  • 38
    • 54349125852 scopus 로고    scopus 로고
    • Podospora anserina: A model organism to study mechanisms of healthy ageing
    • Scheckhuber CQ, Osiewacz HD (2008) Podospora anserina: A model organism to study mechanisms of healthy ageing. Mol Genet Genomics 280:365-374
    • (2008) Mol Genet Genomics , vol.280 , pp. 365-374
    • Scheckhuber, C.Q.1    Osiewacz, H.D.2
  • 39
    • 0025006934 scopus 로고
    • Cloning, sequence, and photoregulation of al-1, a carotenoid biosynthetic gene of Neurospora crassa
    • Schmidhauser TJ, Lauter FR, Russo VE, Yanofsky C (1990) Cloning, sequence, and photoregulation of al-1, a carotenoid biosynthetic gene of Neurospora crassa. Mol Cell Biol 10:5064-5070
    • (1990) Mol Cell Biol , vol.10 , pp. 5064-5070
    • Schmidhauser, T.J.1    Lauter, F.R.2    Russo, V.E.3    Yanofsky, C.4
  • 40
    • 0028291805 scopus 로고
    • Characterization of al-2, the phytoene synthase gene of Neurospora crassa. Cloning, sequence analysis, and photoregulation
    • Schmidhauser TJ, Lauter FR, Schumacher M, Zhou W, Russo VE, Yanofsky C (1994) Characterization of al-2, the phytoene synthase gene of Neurospora crassa. Cloning, sequence analysis, and photoregulation. J Biol Chem 269:12060-12066
    • (1994) J Biol Chem , vol.269 , pp. 12060-12066
    • Schmidhauser, T.J.1    Lauter, F.R.2    Schumacher, M.3    Zhou, W.4    Russo, V.E.5    Yanofsky, C.6
  • 41
    • 0028812116 scopus 로고
    • Carotenoid composition of mycelium and apothecia in the discomycete Scutellinia umbrarum
    • Schrantz JP, Lemoine Y (1995) Carotenoid composition of mycelium and apothecia in the discomycete Scutellinia umbrarum. Photochem 40:33-35
    • (1995) Photochem , vol.40 , pp. 33-35
    • Schrantz, J.P.1    Lemoine, Y.2
  • 42
    • 84989667481 scopus 로고
    • The light-harvesting and protective functions of carotenoids in photosynthetic membranes
    • Siefermann-Harms D (1987) The light-harvesting and protective functions of carotenoids in photosynthetic membranes. Physiol Plant 69:661-668
    • (1987) Physiol Plant , vol.69 , pp. 661-668
    • Siefermann-Harms, D.1
  • 43
    • 1242345186 scopus 로고    scopus 로고
    • Impact of a disruption of a pathway delivering copper to mitochondria on Podospora anserina metabolism and life span
    • Stumpferl SW, Stephan O, Osiewacz HD (2004) Impact of a disruption of a pathway delivering copper to mitochondria on Podospora anserina metabolism and life span. Eukaryot Cell 3:200-211
    • (2004) Eukaryot Cell , vol.3 , pp. 200-211
    • Stumpferl, S.W.1    Stephan, O.2    Osiewacz, H.D.3
  • 44
    • 26944436224 scopus 로고    scopus 로고
    • Characterization of a gene in the car cluster of Fusarium fujikuroi that codes for a protein of the carotenoid oxygenase family
    • Thewes S, Prado-Cabrero A, Prado MM, Tudzynski B, Avalos J (2005) Characterization of a gene in the car cluster of Fusarium fujikuroi that codes for a protein of the carotenoid oxygenase family. Mol Genet Genomics 274:217-228
    • (2005) Mol Genet Genomics , vol.274 , pp. 217-228
    • Thewes, S.1    Prado-Cabrero, A.2    Prado, M.M.3    Tudzynski, B.4    Avalos, J.5
  • 45
    • 0037479864 scopus 로고    scopus 로고
    • Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma)
    • Verdoes CJ, Sandmann G, Visser H, Diaz M, van Mossel M, van Ooyen AJJ (2003) Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma). Appl Environ Microbiol 69:3728-3738
    • (2003) Appl Environ Microbiol , vol.69 , pp. 3728-3738
    • Verdoes, C.J.1    Sandmann, G.2    Visser, H.3    Diaz, M.4    van Mossel, M.5    van Ooyen, A.J.J.6
  • 46
    • 34447543117 scopus 로고    scopus 로고
    • High level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous
    • Verwaal R, Wang J, Meijnen JP, Visser H, Sandmann G, van den Berg JA, van Ooyen AJ (2007) High level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous. Appl Environ Microbiol 73:4342-4350
    • (2007) Appl Environ Microbiol , vol.73 , pp. 4342-4350
    • Verwaal, R.1    Wang, J.2    Meijnen, J.P.3    Visser, H.4    Sandmann, G.5    van den Berg, J.A.6    van Ooyen, A.J.7
  • 47
    • 0021200309 scopus 로고
    • The photosensitivity of pigmented and non-pigmented strains of Ustilago violacea
    • Will OH, Newland NA, Reppe CR (1984) The photosensitivity of pigmented and non-pigmented strains of Ustilago violacea. Curr Microbiol 10:295-302
    • (1984) Curr Microbiol , vol.10 , pp. 295-302
    • Will, O.H.1    Newland, N.A.2    Reppe, C.R.3


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