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Volumn 217, Issue 2, 2009, Pages 302-311

Differentiation-dependent progesterone synthesis and metabolism in NT2-N human neurons

Author keywords

3 hydroxy 5 pregnan 20 one (3 hydroxy 5 tetrahydroprogesterone 3 5 THP); 3 hydroxysteroid dehydrogenase (3 HSD); Neuronal differentiation; Neurosteroids; Ntera2 cl.D1, NT2 N; Progesterone; Retinoic acid

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; GLUTAMATE DECARBOXYLASE 67; MESSENGER RNA; PREGNENOLONE; PROGESTERONE; RETINOIC ACID; TRILOSTANE;

EID: 67349266611     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.03.008     Document Type: Article
Times cited : (8)

References (70)
  • 1
    • 0021447637 scopus 로고
    • Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro
    • Andrews P.W. Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev. Biol. 103 (1984) 285-293
    • (1984) Dev. Biol. , vol.103 , pp. 285-293
    • Andrews, P.W.1
  • 2
    • 9744228702 scopus 로고    scopus 로고
    • Neurosteroidogenesis: relevance to neurosteroid actions in brain and modulation by psychotropic drugs
    • Barbaccia M.L. Neurosteroidogenesis: relevance to neurosteroid actions in brain and modulation by psychotropic drugs. Crit. Rev. Neurobiol. 16 (2004) 67-74
    • (2004) Crit. Rev. Neurobiol. , vol.16 , pp. 67-74
    • Barbaccia, M.L.1
  • 3
    • 21344436812 scopus 로고    scopus 로고
    • A receptor active neurosteroids and the sedative/hypnoyic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S(sensitive) and GHB-R(resistant) rat lines
    • A receptor active neurosteroids and the sedative/hypnoyic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S(sensitive) and GHB-R(resistant) rat lines. Neuropharmacology 49 (2005) 48-58
    • (2005) Neuropharmacology , vol.49 , pp. 48-58
    • Barbaccia, M.L.1    Carai, M.A.M.2    Colombo, G.3    Lobina, C.4    Purdy, R.H.5    Gessa, G.L.6
  • 4
    • 0025277679 scopus 로고
    • Expression of steroid metabolizing enzymes by aggregating fetal brain cells in culture: a model for developmental regulation of the progesterone 5α-reductase pathway
    • Barnea A., Hajibeigi A., Trant J.M., and Mason J.I. Expression of steroid metabolizing enzymes by aggregating fetal brain cells in culture: a model for developmental regulation of the progesterone 5α-reductase pathway. Endocrinology 127 (1990) 500-502
    • (1990) Endocrinology , vol.127 , pp. 500-502
    • Barnea, A.1    Hajibeigi, A.2    Trant, J.M.3    Mason, J.I.4
  • 5
    • 0025737587 scopus 로고
    • Neurosteroids: a new function in the brain
    • Baulieu E.-E. Neurosteroids: a new function in the brain. Biol. Cell 71 (1991) 3-10
    • (1991) Biol. Cell , vol.71 , pp. 3-10
    • Baulieu, E.-E.1
  • 6
    • 21744447595 scopus 로고    scopus 로고
    • Neurosteroids: endogenous regulators of the GABA(A) receptor
    • Belelli D., and Lambert J.J. Neurosteroids: endogenous regulators of the GABA(A) receptor. Nature Rev. Neurosci. 6 (2005) 565-575
    • (2005) Nature Rev. Neurosci. , vol.6 , pp. 565-575
    • Belelli, D.1    Lambert, J.J.2
  • 9
    • 0033969090 scopus 로고    scopus 로고
    • Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and β-amyloid peptide
    • Brown R., Cascio C., and Papadopoulos V. Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and β-amyloid peptide. J. Neurochem. 74 (2000) 847-859
    • (2000) J. Neurochem. , vol.74 , pp. 847-859
    • Brown, R.1    Cascio, C.2    Papadopoulos, V.3
  • 12
    • 0025968644 scopus 로고
    • Inhibition of MAP2 expression affects both morphological and cell division phenotypes of neuronal differentiation
    • Dinsmore J.H., and Solomon F. Inhibition of MAP2 expression affects both morphological and cell division phenotypes of neuronal differentiation. Cell 64 (1991) 817-826
    • (1991) Cell , vol.64 , pp. 817-826
    • Dinsmore, J.H.1    Solomon, F.2
  • 13
    • 0034746426 scopus 로고    scopus 로고
    • Differential regulation of 3 beta-hydroxysteroid dehydrogenase type II and 17 alpha-hydroxylase/lyase P450 in human adrenocortical carcinoma cells by epidermal growth factor and basic fibroblast growth factor
    • Doi J., Takemori H., Ohta M., Nonaka Y., and Okamoto M. Differential regulation of 3 beta-hydroxysteroid dehydrogenase type II and 17 alpha-hydroxylase/lyase P450 in human adrenocortical carcinoma cells by epidermal growth factor and basic fibroblast growth factor. J. Endocrinol. 168 (2001) 87-94
    • (2001) J. Endocrinol. , vol.168 , pp. 87-94
    • Doi, J.1    Takemori, H.2    Ohta, M.3    Nonaka, Y.4    Okamoto, M.5
  • 14
    • 33845909301 scopus 로고    scopus 로고
    • Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat
    • Eaton M.J., Quintero Wolfe S., Martinez M., Hernandez M., Furst C., Huang J., Frydel B.R., and Gòmez-Marin O. Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat. J. Pain 8 (2007) 33-50
    • (2007) J. Pain , vol.8 , pp. 33-50
    • Eaton, M.J.1    Quintero Wolfe, S.2    Martinez, M.3    Hernandez, M.4    Furst, C.5    Huang, J.6    Frydel, B.R.7    Gòmez-Marin, O.8
  • 16
    • 0035542992 scopus 로고    scopus 로고
    • Progesterone and the oligodendroglial lineage: stage dependent biosynthesis and metabolism
    • Gago N., Akwa Y., Sananès N., Guennoun R., Baulieu E.-E., El-Etr M., and Schumacher M. Progesterone and the oligodendroglial lineage: stage dependent biosynthesis and metabolism. Glia 36 (2001) 295-308
    • (2001) Glia , vol.36 , pp. 295-308
    • Gago, N.1    Akwa, Y.2    Sananès, N.3    Guennoun, R.4    Baulieu, E.-E.5    El-Etr, M.6    Schumacher, M.7
  • 17
    • 0036218669 scopus 로고    scopus 로고
    • Positive effect of transplantation of hNT neurons (Ntera2/D1 cell line) in a model of familial Amyotrophic lateral sclerosis
    • Garbuzova-Davis S., Willing A.E., Milliken M., Saporta S., Zigova T., Cahill D.W., and Sanberg P.R. Positive effect of transplantation of hNT neurons (Ntera2/D1 cell line) in a model of familial Amyotrophic lateral sclerosis. Exp. Neurol. 174 (2002) 169-180
    • (2002) Exp. Neurol. , vol.174 , pp. 169-180
    • Garbuzova-Davis, S.1    Willing, A.E.2    Milliken, M.3    Saporta, S.4    Zigova, T.5    Cahill, D.W.6    Sanberg, P.R.7
  • 18
    • 33748987380 scopus 로고    scopus 로고
    • Steroids and glial cell function
    • Garcia-Segura L.M., and Melcangi R.C. Steroids and glial cell function. Glia 54 (2006) 485-498
    • (2006) Glia , vol.54 , pp. 485-498
    • Garcia-Segura, L.M.1    Melcangi, R.C.2
  • 19
    • 0034601131 scopus 로고    scopus 로고
    • Human NT2 neurons express a large variety of neurotransmission phenotypes in vitro
    • Guillemain I., Alonso G., Patey G., Privat A., and Chaudieu I. Human NT2 neurons express a large variety of neurotransmission phenotypes in vitro. J. Comp. Neurol. 422 (2000) 380-395
    • (2000) J. Comp. Neurol. , vol.422 , pp. 380-395
    • Guillemain, I.1    Alonso, G.2    Patey, G.3    Privat, A.4    Chaudieu, I.5
  • 22
    • 38349085880 scopus 로고    scopus 로고
    • Neurosteroids in the fetus and neonate: potential protective role in compromised pregnancies
    • Hirst J.J., Palliser H.K., Yates D.M., Yawno T., and Walker D.W. Neurosteroids in the fetus and neonate: potential protective role in compromised pregnancies. Neurochem. Int. 52 (2008) 602-610
    • (2008) Neurochem. Int. , vol.52 , pp. 602-610
    • Hirst, J.J.1    Palliser, H.K.2    Yates, D.M.3    Yawno, T.4    Walker, D.W.5
  • 24
    • 0024414966 scopus 로고
    • Biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells
    • Jung-Testas I., Hu Z.Y., Robel P., and Baulieu E.-E. Biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells. Endocrinology 12 (1989) 2083-2091
    • (1989) Endocrinology , vol.12 , pp. 2083-2091
    • Jung-Testas, I.1    Hu, Z.Y.2    Robel, P.3    Baulieu, E.-E.4
  • 25
    • 0027546746 scopus 로고
    • Pregnenolone metabolism in rodent embryonic neurons and astrocytes
    • Kabbadj K., El-Etr M., Baulieu E.-E., and Robel P. Pregnenolone metabolism in rodent embryonic neurons and astrocytes. Glia 7 (1993) 170-175
    • (1993) Glia , vol.7 , pp. 170-175
    • Kabbadj, K.1    El-Etr, M.2    Baulieu, E.-E.3    Robel, P.4
  • 27
    • 33750007805 scopus 로고    scopus 로고
    • Characterization of the canine 3beta-hydroxysteroid dehydrogenase and its expression in the corpus luteum during diestrus
    • Kowalewski M.P., Mason J.I., Howie A.F., Morley S.D., Schuler G., and Hoffmann B. Characterization of the canine 3beta-hydroxysteroid dehydrogenase and its expression in the corpus luteum during diestrus. J. Steroid Biochem. Mol. Biol. 101 (2006) 254-2562
    • (2006) J. Steroid Biochem. Mol. Biol. , vol.101 , pp. 254-2562
    • Kowalewski, M.P.1    Mason, J.I.2    Howie, A.F.3    Morley, S.D.4    Schuler, G.5    Hoffmann, B.6
  • 28
    • 0029953789 scopus 로고    scopus 로고
    • Ontogeny of 5α-reductase (type 1) messenger ribonucleic acid expression in rat brain: early presence in germinal zones
    • Lauber M.E., and Lichtensteiger W. Ontogeny of 5α-reductase (type 1) messenger ribonucleic acid expression in rat brain: early presence in germinal zones. Endocrinology 137 (1996) 2718-2730
    • (1996) Endocrinology , vol.137 , pp. 2718-2730
    • Lauber, M.E.1    Lichtensteiger, W.2
  • 29
    • 0037008367 scopus 로고    scopus 로고
    • Allopregnanolone attenuates N-methyl-d-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture
    • Lockhart E.M., Warner D.S., Pearlstein R.D., Penning D.H., Mehrabani S., and Boustany R.M. Allopregnanolone attenuates N-methyl-d-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. Neurosci. Lett. 328 (2002) 33-36
    • (2002) Neurosci. Lett. , vol.328 , pp. 33-36
    • Lockhart, E.M.1    Warner, D.S.2    Pearlstein, R.D.3    Penning, D.H.4    Mehrabani, S.5    Boustany, R.M.6
  • 30
    • 0025295774 scopus 로고
    • Human 3beta-hydroxysteroid dehydrogenase/delta-5-delta-4-isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids
    • Lorence M.C., Murry B.A., Trant J.M., and Mason J.I. Human 3beta-hydroxysteroid dehydrogenase/delta-5-delta-4-isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids. Endocrinology 126 (1990) 2493-2498
    • (1990) Endocrinology , vol.126 , pp. 2493-2498
    • Lorence, M.C.1    Murry, B.A.2    Trant, J.M.3    Mason, J.I.4
  • 32
    • 18844481386 scopus 로고    scopus 로고
    • Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3β-hydroxy-5α-pregnan-20-one (isoallopregnanolone)
    • Lundgren P., Strömberg J., Bäckström T., and Wang M. Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3β-hydroxy-5α-pregnan-20-one (isoallopregnanolone). Brain Res. 982 (2005) 45-53
    • (2005) Brain Res. , vol.982 , pp. 45-53
    • Lundgren, P.1    Strömberg, J.2    Bäckström, T.3    Wang, M.4
  • 33
    • 0026686503 scopus 로고
    • Neuroepithelial cells in the rat spinal cord express glutamate decarboxylase immunoreactivity in vivo and in vitro
    • Ma W., Behar T., Maric D., and Barker J.L. Neuroepithelial cells in the rat spinal cord express glutamate decarboxylase immunoreactivity in vivo and in vitro. J. Comp. Neurol. 325 (1992) 257-270
    • (1992) J. Comp. Neurol. , vol.325 , pp. 257-270
    • Ma, W.1    Behar, T.2    Maric, D.3    Barker, J.L.4
  • 35
    • 0029988536 scopus 로고    scopus 로고
    • Steroid metabolizing enzymes in pluripotential progenitors central nervous system cells: effect of differentiation and maturation
    • Melcangi R., Froelichsthal P., Martini L., and Vescovi A.L. Steroid metabolizing enzymes in pluripotential progenitors central nervous system cells: effect of differentiation and maturation. Neuroscience 72 (1996) 475-476
    • (1996) Neuroscience , vol.72 , pp. 475-476
    • Melcangi, R.1    Froelichsthal, P.2    Martini, L.3    Vescovi, A.L.4
  • 36
    • 34548563903 scopus 로고    scopus 로고
    • Neurosteroid regulation of central nervous system development
    • Mellon S.H. Neurosteroid regulation of central nervous system development. Pharmacol. Ther. 116 (2007) 107-124
    • (2007) Pharmacol. Ther. , vol.116 , pp. 107-124
    • Mellon, S.H.1
  • 38
    • 34247532433 scopus 로고    scopus 로고
    • Timing is everything: making neurons versus glia in the developing cortex
    • Miller F.D., and Gauthier A.S. Timing is everything: making neurons versus glia in the developing cortex. Neuron 54 (2007) 357-369
    • (2007) Neuron , vol.54 , pp. 357-369
    • Miller, F.D.1    Gauthier, A.S.2
  • 40
    • 0034724282 scopus 로고    scopus 로고
    • Pregnenolone binds to microtubule-associated protein-2 and stimulates microtubule assembly
    • Murakami K., Fellous A., Baulieu E.-E., and Robel P. Pregnenolone binds to microtubule-associated protein-2 and stimulates microtubule assembly. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 3579-3584
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 3579-3584
    • Murakami, K.1    Fellous, A.2    Baulieu, E.-E.3    Robel, P.4
  • 41
    • 0033566791 scopus 로고    scopus 로고
    • A receptors expressed in undifferentiated human teratocarcinoma NT2 cells differ from those expressed by differentiated NT2-N cells
    • A receptors expressed in undifferentiated human teratocarcinoma NT2 cells differ from those expressed by differentiated NT2-N cells. J. Neurosci. 19 (1999) 7057-7065
    • (1999) J. Neurosci. , vol.19 , pp. 7057-7065
    • Neelands, T.R.1    Zhang, J.2    McDonald, R.L.3
  • 42
    • 14744274454 scopus 로고    scopus 로고
    • Tumorigenicity issues of embryonic carcinoma-derived stem cells: relevance to surgical trials using NT2 and hNT neural cells
    • Newman M.B., Misiuta I., Willing A.E., Zigova T., Karl R.C., Borlongan C.V., and Sanberg P.R. Tumorigenicity issues of embryonic carcinoma-derived stem cells: relevance to surgical trials using NT2 and hNT neural cells. Stem Cells Dev. 14 (2005) 29-43
    • (2005) Stem Cells Dev. , vol.14 , pp. 29-43
    • Newman, M.B.1    Misiuta, I.2    Willing, A.E.3    Zigova, T.4    Karl, R.C.5    Borlongan, C.V.6    Sanberg, P.R.7
  • 43
    • 60249093114 scopus 로고    scopus 로고
    • 3β-hydroxysteroid dehydrogenases and pre-receptor steroid metabolism in the human ovarian surface epithelium
    • Papacleovoulou G., Edmondson R.J., Critchley H.O.D., Hillier S.G., and Mason J.I. 3β-hydroxysteroid dehydrogenases and pre-receptor steroid metabolism in the human ovarian surface epithelium. Mol. Cell. Endocrinol., 301 (2009) 65-73
    • (2009) Mol. Cell. Endocrinol. , vol.301 , pp. 65-73
    • Papacleovoulou, G.1    Edmondson, R.J.2    Critchley, H.O.D.3    Hillier, S.G.4    Mason, J.I.5
  • 44
    • 35448951796 scopus 로고    scopus 로고
    • Human model neurons in studies of brain cell damage and neural repair
    • Paquet-Durand F., and Bicker G. Human model neurons in studies of brain cell damage and neural repair. Curr. Mol. Medic. 7 (2007) 541-554
    • (2007) Curr. Mol. Medic. , vol.7 , pp. 541-554
    • Paquet-Durand, F.1    Bicker, G.2
  • 45
    • 0038292053 scopus 로고    scopus 로고
    • Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres
    • Paquet-Durand F., Tan S., and Bicker G. Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres. Dev. Brain Res. 142 (2003) 161-167
    • (2003) Dev. Brain Res. , vol.142 , pp. 161-167
    • Paquet-Durand, F.1    Tan, S.2    Bicker, G.3
  • 46
    • 34247097530 scopus 로고    scopus 로고
    • mGluR5 is involved in dendrite differentiation and excitatory synaptic transmission in Ntera2 human embryonic carcinoma cell-derived neurons
    • Park H., Váradi A., Seok H., Jo J., Gilpin H., Liew C.G., Jung S., Andrews P.W., Molnár E., and Cho K. mGluR5 is involved in dendrite differentiation and excitatory synaptic transmission in Ntera2 human embryonic carcinoma cell-derived neurons. Neuropharmacology 52 (2007) 1403-1414
    • (2007) Neuropharmacology , vol.52 , pp. 1403-1414
    • Park, H.1    Váradi, A.2    Seok, H.3    Jo, J.4    Gilpin, H.5    Liew, C.G.6    Jung, S.7    Andrews, P.W.8    Molnár, E.9    Cho, K.10
  • 47
    • 0034287545 scopus 로고    scopus 로고
    • Human 3α-hydroxysteroid dehydrogenase isoforms (AKRC1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
    • Penning T.M., Burczynski M.E., Jez J.M., Hung C.-F., Lin H.-K., Ma H., Moore M., Palackal N., and Ratnam K. Human 3α-hydroxysteroid dehydrogenase isoforms (AKRC1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem. J. 351 (2000) 67-77
    • (2000) Biochem. J. , vol.351 , pp. 67-77
    • Penning, T.M.1    Burczynski, M.E.2    Jez, J.M.3    Hung, C.-F.4    Lin, H.-K.5    Ma, H.6    Moore, M.7    Palackal, N.8    Ratnam, K.9
  • 50
    • 51749097102 scopus 로고    scopus 로고
    • Neurosteroid biosynthesis regulates sexually dimorphic fear and aggression behavior in mice
    • Pinna G., Agis-Balboa C.R., Pibiri F., Nelson M., Guidotti A., and Costa E. Neurosteroid biosynthesis regulates sexually dimorphic fear and aggression behavior in mice. Neurochem. Res. 33 (2008) 1990-2007
    • (2008) Neurochem. Res. , vol.33 , pp. 1990-2007
    • Pinna, G.1    Agis-Balboa, C.R.2    Pibiri, F.3    Nelson, M.4    Guidotti, A.5    Costa, E.6
  • 51
    • 0033037443 scopus 로고    scopus 로고
    • Neurotrophins differentially regulate the survival and morphological complexity of human CNS model neurons
    • Piontek J., Chen C.C., Kempf M., and Brandt R. Neurotrophins differentially regulate the survival and morphological complexity of human CNS model neurons. J. Neurochem. 73 (1999) 139-146
    • (1999) J. Neurochem. , vol.73 , pp. 139-146
    • Piontek, J.1    Chen, C.C.2    Kempf, M.3    Brandt, R.4
  • 52
    • 0027219982 scopus 로고
    • Ntera-2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell
    • Pleasure S.J., and Lee V.M.Y. Ntera-2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell. J. Neurosci. Res. 35 (1993) 585-602
    • (1993) J. Neurosci. Res. , vol.35 , pp. 585-602
    • Pleasure, S.J.1    Lee, V.M.Y.2
  • 53
    • 0034654308 scopus 로고    scopus 로고
    • In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta
    • Pomata P.E., Colman-Lerner A.A., Baraňao J.L., and Fiszman M.L. In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta. Dev. Brain Res. 120 (2000) 83-86
    • (2000) Dev. Brain Res. , vol.120 , pp. 83-86
    • Pomata, P.E.1    Colman-Lerner, A.A.2    Baraňao, J.L.3    Fiszman, M.L.4
  • 54
    • 0033784152 scopus 로고    scopus 로고
    • Developmental regulation of neurogenesis in the pluripotent human embryonal carcinoma cell line Ntera-2
    • Przyborski S.A., Morton I.E., Wood A., and Andrews P.W. Developmental regulation of neurogenesis in the pluripotent human embryonal carcinoma cell line Ntera-2. Eur. J. Neurosci. 12 (2000) 3521-3528
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3521-3528
    • Przyborski, S.A.1    Morton, I.E.2    Wood, A.3    Andrews, P.W.4
  • 55
    • 0025353194 scopus 로고
    • Synthesis, metabolism and pharmacological activity of 3α-hydroxy-steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes
    • Purdy R.H., Morrow A.L., Blinn J.R., and Paul S.M. Synthesis, metabolism and pharmacological activity of 3α-hydroxy-steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes. J. Med. Chem. 33 (1990) 1572-1581
    • (1990) J. Med. Chem. , vol.33 , pp. 1572-1581
    • Purdy, R.H.1    Morrow, A.L.2    Blinn, J.R.3    Paul, S.M.4
  • 57
    • 0026378756 scopus 로고
    • Structure and expression of a new complementary-DNA encoding the almost exclusive 3-beta-hydroxysteroid dehydrogenase delta-5-delta-4-isomerase in human adrenals and gonads
    • Rheaume E., Lachance Y., Zhao H.F., Breton N., Dumont M., Delaunoit Y., Trudel C., Luu-The V., Simard J., and Labrie F. Structure and expression of a new complementary-DNA encoding the almost exclusive 3-beta-hydroxysteroid dehydrogenase delta-5-delta-4-isomerase in human adrenals and gonads. Mol. Endocrinol. 5 (1991) 1147-1157
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1147-1157
    • Rheaume, E.1    Lachance, Y.2    Zhao, H.F.3    Breton, N.4    Dumont, M.5    Delaunoit, Y.6    Trudel, C.7    Luu-The, V.8    Simard, J.9    Labrie, F.10
  • 58
    • 18644384781 scopus 로고    scopus 로고
    • Trophic actions of GABA on neuronal development
    • Represa A., and Ben-Ari Y. Trophic actions of GABA on neuronal development. Trends Neurosci. 28 (2005) 278-283
    • (2005) Trends Neurosci. , vol.28 , pp. 278-283
    • Represa, A.1    Ben-Ari, Y.2
  • 59
    • 0031843632 scopus 로고    scopus 로고
    • Modulation of neurosteroid synthesis/accumulation by L-ascorbic acid in rat brain tissue: inhibition by selected serotini antagonists
    • Roscetti G., Del Carmine R., Trabucchi M., Massotti M., and Barbaccia M.L. Modulation of neurosteroid synthesis/accumulation by L-ascorbic acid in rat brain tissue: inhibition by selected serotini antagonists. J. Neurochem. 71 (1998) 1108-1117
    • (1998) J. Neurochem. , vol.71 , pp. 1108-1117
    • Roscetti, G.1    Del Carmine, R.2    Trabucchi, M.3    Massotti, M.4    Barbaccia, M.L.5
  • 60
    • 0037293399 scopus 로고    scopus 로고
    • Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties
    • Rupprecht R. Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 28 (2003) 139-168
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 139-168
    • Rupprecht, R.1
  • 61
    • 0035882468 scopus 로고    scopus 로고
    • Effects of progesterone synthesized de novo in the developing purkinje cell on its dendritic growth and synaptogenesis
    • Sakamoto H., Ukena K., and Tsutsui K. Effects of progesterone synthesized de novo in the developing purkinje cell on its dendritic growth and synaptogenesis. J. Neurosci. 21 (2001) 6221-6232
    • (2001) J. Neurosci. , vol.21 , pp. 6221-6232
    • Sakamoto, H.1    Ukena, K.2    Tsutsui, K.3
  • 62
    • 34548610385 scopus 로고    scopus 로고
    • Progesterone: therapeutic opportunities for neuroprotection and myelin repair
    • Schumacher M., Guennoun R., Stein D.G., and De Nicola A.F. Progesterone: therapeutic opportunities for neuroprotection and myelin repair. Pharmacol. Ther. 116 (2007) 77-106
    • (2007) Pharmacol. Ther. , vol.116 , pp. 77-106
    • Schumacher, M.1    Guennoun, R.2    Stein, D.G.3    De Nicola, A.F.4
  • 63
    • 0029657789 scopus 로고    scopus 로고
    • Regulation of intracellular Ca2+ in response to muscarinic and glutamate receptor agonists during the differentiation of NTERA2 human embryonal carcinoma cells into neurons
    • Squires P.E., Wakeman J.A., Chapman H., Kumpf S., Fidock M.D., Andrews P.W., and Dunne M.J. Regulation of intracellular Ca2+ in response to muscarinic and glutamate receptor agonists during the differentiation of NTERA2 human embryonal carcinoma cells into neurons. Eur. J. Neurosci. 8 (1996) 783-793
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 783-793
    • Squires, P.E.1    Wakeman, J.A.2    Chapman, H.3    Kumpf, S.4    Fidock, M.D.5    Andrews, P.W.6    Dunne, M.J.7
  • 64
    • 1342330548 scopus 로고    scopus 로고
    • Neurosteroid biosynthesis in the human brain and its clinical implications
    • Stoffel-Wagner B. Neurosteroid biosynthesis in the human brain and its clinical implications. Ann. New York Acad. Sci. 1007 (2003) 64-78
    • (2003) Ann. New York Acad. Sci. , vol.1007 , pp. 64-78
    • Stoffel-Wagner, B.1
  • 65
    • 85047676517 scopus 로고    scopus 로고
    • -4-isomerase in the rat Purkinje neuron during neonatal life
    • -4-isomerase in the rat Purkinje neuron during neonatal life. Endocrinology 140 (1999) 805-813
    • (1999) Endocrinology , vol.140 , pp. 805-813
    • Ukena, K.1    Kohchi, C.2    Tsutsui, K.3
  • 66
    • 44249093230 scopus 로고    scopus 로고
    • Progesterone receptors and neural development: a gap between bench and bedside?
    • Wagner C.K. Progesterone receptors and neural development: a gap between bench and bedside?. Endocrinology 149 (2008) 2743-2749
    • (2008) Endocrinology , vol.149 , pp. 2743-2749
    • Wagner, C.K.1
  • 67
    • 18644371723 scopus 로고    scopus 로고
    • The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression
    • Wang J.M., Johnston P.B., Ball B.G., and Brinton R.D. The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression. J. Neurosci. 25 (2005) 4706-4718
    • (2005) J. Neurosci. , vol.25 , pp. 4706-4718
    • Wang, J.M.1    Johnston, P.B.2    Ball, B.G.3    Brinton, R.D.4
  • 69
    • 0030823417 scopus 로고    scopus 로고
    • Expression of glutamic acid decarboxylase during human neuronal differentiation: studies using the Ntera-2 culture system
    • Yoshioka A., Yudkoff M., and Pleasure D. Expression of glutamic acid decarboxylase during human neuronal differentiation: studies using the Ntera-2 culture system. Brain Res. 767 (1997) 333-339
    • (1997) Brain Res. , vol.767 , pp. 333-339
    • Yoshioka, A.1    Yudkoff, M.2    Pleasure, D.3
  • 70
    • 0033305132 scopus 로고    scopus 로고
    • Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain
    • Zwain I.H., and Yen S.S.C. Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain. Endocrinology 140 (1999) 385-3843
    • (1999) Endocrinology , vol.140 , pp. 385-3843
    • Zwain, I.H.1    Yen, S.S.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.