Pathways of neurosteroid biosynthesis in cell lines from human brain: Regulation of dehydroepiandrosterone formation by oxidative stress and β- amyloid peptide

Journal of Neurochemistry

Volumn 74, Issue 2, 2000, Pages 847-859

  Brown, Rachel C ^a   Cascio, Caterina ^a,b   Papadopoulos, Vassilios ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF PALERMO   (Italy)

Author keywords

Amyloid; Dehydroepiandrosterone; Free radicals; Pregnenolone; Steroidogenesis

Indexed keywords

AMYLOID BETA PROTEIN; NEUROSTEROID; PRASTERONE;

ARTICLE; ASTROCYTE; BRAIN METABOLISM; CELL LINE; DRUG EFFECT; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE; NERVE DEGENERATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; STEROIDOGENESIS;

3-HYDROXYSTEROID DEHYDROGENASES; AMYLOID BETA-PROTEIN; ASTROCYTES; BRAIN; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; DEHYDROEPIANDROSTERONE; FERROUS COMPOUNDS; HUMANS; INTRACELLULAR MEMBRANES; NEURONS; OLIGODENDROGLIA; OXIDATIVE STRESS; PREGNENOLONE; REACTIVE OXYGEN SPECIES; RECEPTORS, GABA-A; RNA, MESSENGER; STEROID 17-ALPHA-HYDROXYLASE; STEROIDS; TUMOR CELLS, CULTURED;

EID: 0033969090     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.740847.x     Document Type: Article

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