Generation of new TRAIL mutants DR5-A and DR5-B with improved selectivity to death receptor 5

Apoptosis

Volumn 14, Issue 6, 2009, Pages 778-787

  Gasparian, Marine E ^a   Chernyak, Boris V ^b   Dolgikh, Dmitry A ^a   Yagolovich, Anne V ^a   Popova, Ekaterina N ^b   Sycheva, Anna M ^c   Moshkovskii, Sergey A ^c   Kirpichnikov, Mikhail P ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

Apoptosis; Death receptors; Decoy receptors; TRAIL

Indexed keywords

CYTOCHALASIN D; DEATH RECEPTOR; DEATH RECEPTOR 5; DEATH RECEPTOR 5 A; DEATH RECEPTOR 5 B; OSTEOPROTEGERIN; PACLITAXEL; PROTEIN BCL 2; SOLUBLE RECEPTOR OSTEOPROTEGERIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL LINE; CONTROLLED STUDY; CYTOSKELETON; DISSOCIATION CONSTANT; ESCHERICHIA COLI; HELA CELL; HUMAN; HUMAN CELL; MUTANT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN INTERACTION; RECEPTOR BINDING; SURFACE PLASMON RESONANCE; WILD TYPE;

AMINO ACID SUBSTITUTION; APOPTOSIS; CELL LINE, TUMOR; CYTOCHALASIN D; HUMANS; KINETICS; MUTANT PROTEINS; MUTATION; PACLITAXEL; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SURFACE PLASMON RESONANCE; TNF-RELATED APOPTOSIS-INDUCING LIGAND; ULTRACENTRIFUGATION;

ESCHERICHIA COLI;

EID: 67349257914     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0349-3     Document Type: Article

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