-
1
-
-
0027930409
-
Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene
-
Adams M., Matthews C., Collingwood T.N., Tone Y., Beck-Peccoz P., and Chatterjee K.K. Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene. J. Clin. Invest. 94 (1994) 506-515
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 506-515
-
-
Adams, M.1
Matthews, C.2
Collingwood, T.N.3
Tone, Y.4
Beck-Peccoz, P.5
Chatterjee, K.K.6
-
2
-
-
0034837089
-
Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance
-
Ando S., Sarlis N.J., Krishnan J., Feng X., Refetoff S., Zhang M.Q., Oldfield E.H., and Yen P.M. Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance. Mol. Endocrinol. 15 (2001) 1529-1538
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1529-1538
-
-
Ando, S.1
Sarlis, N.J.2
Krishnan, J.3
Feng, X.4
Refetoff, S.5
Zhang, M.Q.6
Oldfield, E.H.7
Yen, P.M.8
-
3
-
-
0034747060
-
Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor
-
Ando S., Sarlis N.J., Oldfield E.H., and Yen P.M. Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor. J. Clin. Endocrinol. Metab. 86 (2001) 5572-5576
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 5572-5576
-
-
Ando, S.1
Sarlis, N.J.2
Oldfield, E.H.3
Yen, P.M.4
-
4
-
-
0028133444
-
Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v-erbA
-
Barlow C., Meister B., Lardelli M., Lendahl U., and Vennström B. Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v-erbA. EMBO J. 15 13 (1994) 4241-4250
-
(1994)
EMBO J.
, vol.15
, Issue.13
, pp. 4241-4250
-
-
Barlow, C.1
Meister, B.2
Lardelli, M.3
Lendahl, U.4
Vennström, B.5
-
5
-
-
84995819775
-
Expression of thyrotropin receptor and thyroid hormone receptor messenger ribonucleic acid in normal, hyperplastic, and neoplastic human thyroid tissue
-
Bronnegard M., Torring O., Boos J., Sylven C., Marcus C., and Wallin G. Expression of thyrotropin receptor and thyroid hormone receptor messenger ribonucleic acid in normal, hyperplastic, and neoplastic human thyroid tissue. J. Clin. Endocrinol. Metab. 79 (1994) 384-389
-
(1994)
J. Clin. Endocrinol. Metab.
, vol.79
, pp. 384-389
-
-
Bronnegard, M.1
Torring, O.2
Boos, J.3
Sylven, C.4
Marcus, C.5
Wallin, G.6
-
6
-
-
11244346968
-
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts
-
Cao X., Kambe F., Moeller L.C., Refetoff S., and Seo H. Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Mol. Endocrinol. 19 (2005) 102-112
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 102-112
-
-
Cao, X.1
Kambe, F.2
Moeller, L.C.3
Refetoff, S.4
Seo, H.5
-
7
-
-
1242341408
-
Thyroid hormone receptor mutations in cancer
-
Cheng S.-y. Thyroid hormone receptor mutations in cancer. Mol. Cell. Endocrinol. 213 (2003) 23-30
-
(2003)
Mol. Cell. Endocrinol.
, vol.213
, pp. 23-30
-
-
Cheng, S.-y.1
-
8
-
-
18044374092
-
Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance
-
Cheng S.-y. Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance. Trends Endocrinol. Metab. 16 (2005) 176-182
-
(2005)
Trends Endocrinol. Metab.
, vol.16
, pp. 176-182
-
-
Cheng, S.-y.1
-
9
-
-
0034255143
-
Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors
-
Dace A., Zhao L., Park K.S., Furuno T., Takamura N., Nakanishi M., West B.L., Hanover J.A., and Cheng S. Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors. Proc. Natl Acad. Sci. U. S. A. 97 (2000) 8985-8990
-
(2000)
Proc. Natl Acad. Sci. U. S. A.
, vol.97
, pp. 8985-8990
-
-
Dace, A.1
Zhao, L.2
Park, K.S.3
Furuno, T.4
Takamura, N.5
Nakanishi, M.6
West, B.L.7
Hanover, J.A.8
Cheng, S.9
-
10
-
-
0036299115
-
Role of PTEN, a lipid phosphatase upstream effector of protein kinase B, in epithelial thyroid carcinogenesis
-
Eng C. Role of PTEN, a lipid phosphatase upstream effector of protein kinase B, in epithelial thyroid carcinogenesis. Ann. N. Y. Acad. Sci. 968 (2002) 213-221
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.968
, pp. 213-221
-
-
Eng, C.1
-
11
-
-
11144349646
-
An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis
-
Furumoto H., Ying H., Chandramouli G.V., Zhao L., Walker R.L., Meltzer P.S., Willingham M.C., and Cheng S.-y. An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis. Mol. Cell. Biol. 25 (2005) 124-135
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 124-135
-
-
Furumoto, H.1
Ying, H.2
Chandramouli, G.V.3
Zhao, L.4
Walker, R.L.5
Meltzer, P.S.6
Willingham, M.C.7
Cheng, S.-y.8
-
12
-
-
34548268059
-
Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling
-
Furuya F., Guigon C.J., Zhao L., Lu C., Hanover J.A., and Cheng S.-y. Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling. Mol. Cell. Biol. 27 (2007) 6116-6126
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6116-6126
-
-
Furuya, F.1
Guigon, C.J.2
Zhao, L.3
Lu, C.4
Hanover, J.A.5
Cheng, S.-y.6
-
13
-
-
32444445924
-
Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor
-
Furuya F., Hanover J.A., and Cheng S.-y. Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 1780-1785
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 1780-1785
-
-
Furuya, F.1
Hanover, J.A.2
Cheng, S.-y.3
-
14
-
-
36949013479
-
Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer
-
Furuya F., Lu C., Willingham M.C., and Cheng S.-y. Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer. Carcinogenesis 28 (2007) 2451-2458
-
(2007)
Carcinogenesis
, vol.28
, pp. 2451-2458
-
-
Furuya, F.1
Lu, C.2
Willingham, M.C.3
Cheng, S.-y.4
-
15
-
-
0033561515
-
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma
-
Garcia-Rostan G., Tallini G., Herrero A., D'Aquila T.G., Carcangiu M.L., and Rimm D.L. Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res. 59 (1999) 1811-1815
-
(1999)
Cancer Res.
, vol.59
, pp. 1811-1815
-
-
Garcia-Rostan, G.1
Tallini, G.2
Herrero, A.3
D'Aquila, T.G.4
Carcangiu, M.L.5
Rimm, D.L.6
-
16
-
-
47049089117
-
Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor
-
Guigon C.J., Zhao L., Lu C., Willingham M.C., and Cheng S.-y. Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor. Mol. Cell. Biol. 28 (2008) 4598-4608
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4598-4608
-
-
Guigon, C.J.1
Zhao, L.2
Lu, C.3
Willingham, M.C.4
Cheng, S.-y.5
-
17
-
-
0034749485
-
Transforming events in thyroid tumorigenesis and their association with follicular lesions
-
Heaney A.P., Nelson V., Fernando M., and Horwitz G. Transforming events in thyroid tumorigenesis and their association with follicular lesions. J. Clin. Endocrinol. Metab. 86 (2001) 5025-5032
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 5025-5032
-
-
Heaney, A.P.1
Nelson, V.2
Fernando, M.3
Horwitz, G.4
-
18
-
-
0034716480
-
Expression of pituitary-tumour transforming gene in colorectal tumours
-
Heaney A.P., Singson R., McCabe C.J., Nelson V., Nakashima M., and Melmed S. Expression of pituitary-tumour transforming gene in colorectal tumours. Lancet 355 (2000) 716-719
-
(2000)
Lancet
, vol.355
, pp. 716-719
-
-
Heaney, A.P.1
Singson, R.2
McCabe, C.J.3
Nelson, V.4
Nakashima, M.5
Melmed, S.6
-
20
-
-
33749003446
-
Rapid nongenomic actions of thyroid hormone
-
Hiroi Y., Kim H.H., Ying H., Furuya F., Huang Z., Simoncini T., Noma K., Ueki K., Nguyen N.H., Scanlan T.S., Moskowitz M.A., Cheng S.Y., and Liao J.K. Rapid nongenomic actions of thyroid hormone. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 14104-14109
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 14104-14109
-
-
Hiroi, Y.1
Kim, H.H.2
Ying, H.3
Furuya, F.4
Huang, Z.5
Simoncini, T.6
Noma, K.7
Ueki, K.8
Nguyen, N.H.9
Scanlan, T.S.10
Moskowitz, M.A.11
Cheng, S.Y.12
Liao, J.K.13
-
21
-
-
24644480749
-
Molecular requirements for epithelial-mesenchymal transition during tumor progression
-
Huber M.A., Kraut N., and Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr. Opin. Cell Biol. 17 (2005) 548-558
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 548-558
-
-
Huber, M.A.1
Kraut, N.2
Beug, H.3
-
23
-
-
0022453333
-
DNA aneuploidy in follicular adenomas of the thyroid gland
-
Joensuu H., Klemi P., and Eerola E. DNA aneuploidy in follicular adenomas of the thyroid gland. Am. J. Pathol. 124 (1986) 373-376
-
(1986)
Am. J. Pathol.
, vol.124
, pp. 373-376
-
-
Joensuu, H.1
Klemi, P.2
Eerola, E.3
-
24
-
-
0023690656
-
DNA aneuploidy in adenomas of endocrine organs
-
Joensuu H., and Klemi P.J. DNA aneuploidy in adenomas of endocrine organs. Am. J. Pathol. 132 (1988) 145-151
-
(1988)
Am. J. Pathol.
, vol.132
, pp. 145-151
-
-
Joensuu, H.1
Klemi, P.J.2
-
25
-
-
0036200861
-
Expression of mutant thyroid hormone nuclear receptors is associated with human renal clear cell carcinoma
-
Kamiya Y., Puzianowska-Kuznicka M., McPhie P., Nauman J., Cheng S.-y., and Nauman A. Expression of mutant thyroid hormone nuclear receptors is associated with human renal clear cell carcinoma. Carcinogenesis 23 (2002) 25-33
-
(2002)
Carcinogenesis
, vol.23
, pp. 25-33
-
-
Kamiya, Y.1
Puzianowska-Kuznicka, M.2
McPhie, P.3
Nauman, J.4
Cheng, S.-y.5
Nauman, A.6
-
26
-
-
12944311040
-
Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone
-
Kaneshige M., Kaneshige K., Zhu X., Dace A., Garrett L., Carter T.A., Kazlauskaite R., Pankratz D.G., Wynshaw-Boris A., Refetoff S., Weintraub B., Willingham M.C., Barlow C., and Cheng S. Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 13209-13214
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 13209-13214
-
-
Kaneshige, M.1
Kaneshige, K.2
Zhu, X.3
Dace, A.4
Garrett, L.5
Carter, T.A.6
Kazlauskaite, R.7
Pankratz, D.G.8
Wynshaw-Boris, A.9
Refetoff, S.10
Weintraub, B.11
Willingham, M.C.12
Barlow, C.13
Cheng, S.14
-
27
-
-
23044442140
-
Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells
-
Kim D., Pemberton H., Stratford A.L., Buelaert K., Watkinson J.C., Lopes V., Franklyn J.A., and McCabe C.J. Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells. Oncogene 24 (2005) 4861-4866
-
(2005)
Oncogene
, vol.24
, pp. 4861-4866
-
-
Kim, D.1
Pemberton, H.2
Stratford, A.L.3
Buelaert, K.4
Watkinson, J.C.5
Lopes, V.6
Franklyn, J.A.7
McCabe, C.J.8
-
28
-
-
34447109798
-
The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer
-
Kim C.S., Ying H., Willingham M.C., and Cheng S.-y. The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer. Carcinogenesis 28 (2007) 932-939
-
(2007)
Carcinogenesis
, vol.28
, pp. 932-939
-
-
Kim, C.S.1
Ying, H.2
Willingham, M.C.3
Cheng, S.-y.4
-
29
-
-
33645302628
-
The epithelial-mesenchymal transition: new insights in signaling, development, and disease
-
Lee J.M., Dedhar S., Kalluri R., and Thompson E.W. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J. Cell. Biol. 172 (2006) 973-981
-
(2006)
J. Cell. Biol.
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
30
-
-
9144254032
-
3,3',5-Triiodo-L-thyronine up-regulation of Na,K-ATPase activity and cell surface expression in alveolar epithelial cells is Src kinase- and phosphoinositide 3-kinase-dependent
-
Lei J., Mariash C.N., and Ingbar D.H. 3,3',5-Triiodo-L-thyronine up-regulation of Na,K-ATPase activity and cell surface expression in alveolar epithelial cells is Src kinase- and phosphoinositide 3-kinase-dependent. J. Biol. Chem. 279 (2004) 47589-47600
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47589-47600
-
-
Lei, J.1
Mariash, C.N.2
Ingbar, D.H.3
-
31
-
-
42049095481
-
T3 increases Na-K-ATPase activity via a MAPK/ERK1/2-dependent pathway in rat adult alveolar epithelial cells
-
Lei J., Mariash C.N., Bhargava M., Wattenberg E.V., and Ingbar D.H. T3 increases Na-K-ATPase activity via a MAPK/ERK1/2-dependent pathway in rat adult alveolar epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 294 (2008) L749-L754
-
(2008)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.294
-
-
Lei, J.1
Mariash, C.N.2
Bhargava, M.3
Wattenberg, E.V.4
Ingbar, D.H.5
-
32
-
-
31044449824
-
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome
-
Li X., Lonard D.M., Jung S.Y., Malovannaya A., Feng Q., Qin J., Tsai S.Y., Tsai M.J., and O'Malley B.W. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell 124 (2006) 381-392
-
(2006)
Cell
, vol.124
, pp. 381-392
-
-
Li, X.1
Lonard, D.M.2
Jung, S.Y.3
Malovannaya, A.4
Feng, Q.5
Qin, J.6
Tsai, S.Y.7
Tsai, M.J.8
O'Malley, B.W.9
-
33
-
-
0036531824
-
Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer
-
Li Z., Meng Z.H., Chandrasekaran R., Kuo W.L., Collins C.C., Gray J.W., and Dairkee S.H. Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer. Cancer Res. 62 (2002) 1939-1943
-
(2002)
Cancer Res.
, vol.62
, pp. 1939-1943
-
-
Li, Z.1
Meng, Z.H.2
Chandrasekaran, R.3
Kuo, W.L.4
Collins, C.C.5
Gray, J.W.6
Dairkee, S.H.7
-
34
-
-
0032850236
-
Expression of mutant thyroid hormone nuclear receptors in human hepatocellular carcinoma cells
-
Lin K.H., Shieh H.Y., Chen S.L., and Hsu H.C. Expression of mutant thyroid hormone nuclear receptors in human hepatocellular carcinoma cells. Mol. Carcinog. 26 (1999) 53-61
-
(1999)
Mol. Carcinog.
, vol.26
, pp. 53-61
-
-
Lin, K.H.1
Shieh, H.Y.2
Chen, S.L.3
Hsu, H.C.4
-
35
-
-
0035947083
-
Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
-
Liu J., Stevens J., Rote C.A., Yost H.J., Hu Y., Neufeld K.L., White R.L., and Matsunami N. Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol. Cell 7 (2001) 927-936
-
(2001)
Mol. Cell
, vol.7
, pp. 927-936
-
-
Liu, J.1
Stevens, J.2
Rote, C.A.3
Yost, H.J.4
Hu, Y.5
Neufeld, K.L.6
White, R.L.7
Matsunami, N.8
-
36
-
-
33746483284
-
Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin
-
Liu J., Wang H., Zuo Y., and Farmer S.R. Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin. Mol. Cell. Biol. 26 (2006) 5827-5837
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5827-5837
-
-
Liu, J.1
Wang, H.2
Zuo, Y.3
Farmer, S.R.4
-
37
-
-
34548252291
-
Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation
-
Lonard D.M., and O'Malley B.W. Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol. Cell. 27 (2007) 691-700
-
(2007)
Mol. Cell.
, vol.27
, pp. 691-700
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
38
-
-
0037322597
-
Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour
-
McCabe C.J., Khaira J.S., Boelaert K., Heaney A.P., Tannahill L.A., Hussain S., Mitchell R., Olliff J., Sheppard M.C., Franklyn J.A., and Gittoes N.J. Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour. Clin. Endocrinol. (Oxf.) 58 (2003) 141-150
-
(2003)
Clin. Endocrinol. (Oxf.)
, vol.58
, pp. 141-150
-
-
McCabe, C.J.1
Khaira, J.S.2
Boelaert, K.3
Heaney, A.P.4
Tannahill, L.A.5
Hussain, S.6
Mitchell, R.7
Olliff, J.8
Sheppard, M.C.9
Franklyn, J.A.10
Gittoes, N.J.11
-
39
-
-
0026539146
-
Variable transcriptional activity and ligand binding of mutant beta 1,3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone
-
Meier C.A., Dickstein B.M., Ashizawa K., McClaskey J.H., Muchmore P., Ransom S.C., Menke J.B., Hao E.H., Usala S.J., Bercu B.B., Cheng S.-y., and Weintraub B.D. Variable transcriptional activity and ligand binding of mutant beta 1,3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone. Mol. Endocrinol. 6 (1992) 248-258
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 248-258
-
-
Meier, C.A.1
Dickstein, B.M.2
Ashizawa, K.3
McClaskey, J.H.4
Muchmore, P.5
Ransom, S.C.6
Menke, J.B.7
Hao, E.H.8
Usala, S.J.9
Bercu, B.B.10
Cheng, S.-y.11
Weintraub, B.D.12
-
40
-
-
0037295455
-
Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues
-
Miyakawa M., Tsushima T., Murakami H., Wakai K., Isozaki O., and Takano K. Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues. Endocrinol. J. 50 (2003) 77-83
-
(2003)
Endocrinol. J.
, vol.50
, pp. 77-83
-
-
Miyakawa, M.1
Tsushima, T.2
Murakami, H.3
Wakai, K.4
Isozaki, O.5
Takano, K.6
-
41
-
-
0037205007
-
The promise and perils of Wnt signaling through beta-catenin
-
Moon R.T., Bowerman B., Boutros M., and Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science 296 (2002) 1644-1646
-
(2002)
Science
, vol.296
, pp. 1644-1646
-
-
Moon, R.T.1
Bowerman, B.2
Boutros, M.3
Perrimon, N.4
-
42
-
-
8544247944
-
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease
-
Nelen M.R., van Staveren W.C., Peeters E.A., Hassel M.B., Gorlin R.J., Hamm H., Lindboe C.F., Fryns J.P., Sijmons R.H., Woods D.G., Mariman E.C., Padberg G.W., and Kremer H. Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. Hum. Mol. Genet. 6 (1997) 1383-1387
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 1383-1387
-
-
Nelen, M.R.1
van Staveren, W.C.2
Peeters, E.A.3
Hassel, M.B.4
Gorlin, R.J.5
Hamm, H.6
Lindboe, C.F.7
Fryns, J.P.8
Sijmons, R.H.9
Woods, D.G.10
Mariman, E.C.11
Padberg, G.W.12
Kremer, H.13
-
43
-
-
0037057801
-
The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system
-
Neri L.M., Borgatti P., Capitani S., and Martelli A.M. The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system. Biochim. Biophys. Acta 1584 (2002) 73-80
-
(2002)
Biochim. Biophys. Acta
, vol.1584
, pp. 73-80
-
-
Neri, L.M.1
Borgatti, P.2
Capitani, S.3
Martelli, A.M.4
-
44
-
-
0037633770
-
A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone
-
O'Shea P.J., Harvey C.B., Suzuki H., Kaneshige M., Kaneshige K., Cheng S.-y., and Williams G.R. A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone. Mol. Endocrinol. 17 (2003) 1410-1424
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1410-1424
-
-
O'Shea, P.J.1
Harvey, C.B.2
Suzuki, H.3
Kaneshige, M.4
Kaneshige, K.5
Cheng, S.-y.6
Williams, G.R.7
-
45
-
-
0025719665
-
Homozygosity for a dominant negative thyroid hormone receptor gene responsible for generalized resistance to thyroid hormone
-
Ono S., Schwartz I.D., Mueller O.T., Root A.W., Usala S.J., and Bercu B.B. Homozygosity for a dominant negative thyroid hormone receptor gene responsible for generalized resistance to thyroid hormone. J. Clin. Endocrinol. Metab. 73 (1991) 990-994
-
(1991)
J. Clin. Endocrinol. Metab.
, vol.73
, pp. 990-994
-
-
Ono, S.1
Schwartz, I.D.2
Mueller, O.T.3
Root, A.W.4
Usala, S.J.5
Bercu, B.B.6
-
46
-
-
0026320853
-
Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain
-
Parrilla R., Mixson A.J., McPherson J.A., McClaskey J.H., and Weintraub B.D. Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain. J. Clin. Invest. 88 (1991) 2123-2130
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 2123-2130
-
-
Parrilla, R.1
Mixson, A.J.2
McPherson, J.A.3
McClaskey, J.H.4
Weintraub, B.D.5
-
47
-
-
0037162282
-
Casein kinase 1: a Wnt'er of disconnect
-
Polakis P. Casein kinase 1: a Wnt'er of disconnect. Curr. Biol. 12 (2002) R499-R501
-
(2002)
Curr. Biol.
, vol.12
-
-
Polakis, P.1
-
48
-
-
33846193290
-
The many ways of Wnt in cancer
-
Polakis P. The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17 (2007) 45-51
-
(2007)
Curr. Opin. Genet. Dev.
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
49
-
-
0036964285
-
Functionally impaired TR mutants are present in thyroid papillary cancer
-
Puzianowska-Kuznicka M., Krystyniak A., Madej A., Cheng S.-y., and Nauman J. Functionally impaired TR mutants are present in thyroid papillary cancer. J. Clin. Endocrinol. Metab. 87 (2002) 1120-1128
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1120-1128
-
-
Puzianowska-Kuznicka, M.1
Krystyniak, A.2
Madej, A.3
Cheng, S.-y.4
Nauman, J.5
-
50
-
-
0034738823
-
Expression of thyroid hormone receptors is disturbed in human renal clear cell carcinoma
-
Puzianowska-Kuznicka M., Nauman A., Madej A., Tanski Z., Cheng S., and Nauman J. Expression of thyroid hormone receptors is disturbed in human renal clear cell carcinoma. Cancer Lett. 155 (2000) 145-152
-
(2000)
Cancer Lett.
, vol.155
, pp. 145-152
-
-
Puzianowska-Kuznicka, M.1
Nauman, A.2
Madej, A.3
Tanski, Z.4
Cheng, S.5
Nauman, J.6
-
51
-
-
0027241002
-
The syndromes of resistance to thyroid hormone
-
Refetoff S., Weiss R.E., and Usala S.J. The syndromes of resistance to thyroid hormone. Endocrinol. Rev. 14 (1993) 348-399
-
(1993)
Endocrinol. Rev.
, vol.14
, pp. 348-399
-
-
Refetoff, S.1
Weiss, R.E.2
Usala, S.J.3
-
52
-
-
0035881322
-
Overexpression and overactivation of Akt in thyroid carcinoma
-
Ringel M.D., Hayre N., Saito J., Saunier B., Schuppert F., Burch H., Bernet V., Burman K.D., Kohn L.D., and Saji M. Overexpression and overactivation of Akt in thyroid carcinoma. Cancer Res. 61 (2001) 6105-6111
-
(2001)
Cancer Res.
, vol.61
, pp. 6105-6111
-
-
Ringel, M.D.1
Hayre, N.2
Saito, J.3
Saunier, B.4
Schuppert, F.5
Burch, H.6
Bernet, V.7
Burman, K.D.8
Kohn, L.D.9
Saji, M.10
-
53
-
-
0035050879
-
A pituitary tumor in a patient with thyroid hormone resistance: a diagnostic dilemma
-
Safer J.D., Colan S.D., Fraser L.M., and Wondisford F.E. A pituitary tumor in a patient with thyroid hormone resistance: a diagnostic dilemma. Thyroid 11 (2001) 281-291
-
(2001)
Thyroid
, vol.11
, pp. 281-291
-
-
Safer, J.D.1
Colan, S.D.2
Fraser, L.M.3
Wondisford, F.E.4
-
54
-
-
0024400724
-
Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product
-
Sap J., Munoz A., Schmitt J., Stunnenberg H., and Vennstrom B. Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product. Nature 340 (1989) 242-244
-
(1989)
Nature
, vol.340
, pp. 242-244
-
-
Sap, J.1
Munoz, A.2
Schmitt, J.3
Stunnenberg, H.4
Vennstrom, B.5
-
55
-
-
33749072714
-
Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain
-
Sardi S.P., Murtie J., Koirala S., Patten B.A., and Corfas G. Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. Cell 127 (2006) 185-197
-
(2006)
Cell
, vol.127
, pp. 185-197
-
-
Sardi, S.P.1
Murtie, J.2
Koirala, S.3
Patten, B.A.4
Corfas, G.5
-
56
-
-
4143065010
-
Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway
-
Sharma C., Pradeep A., Wong L., Rana A., and Rana B. Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway. J. Biol. Chem. 279 (2004) 35583-35594
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35583-35594
-
-
Sharma, C.1
Pradeep, A.2
Wong, L.3
Rana, A.4
Rana, B.5
-
57
-
-
0030793795
-
Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism
-
Shepherd P.R., Nave B.T., Rincon J., Haigh R.J., Foulstone E., Proud C., Zierath J.R., Siddle K., and Wallberg-Henriksson H. Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism. Diabetologia 40 (1997) 1172-1177
-
(1997)
Diabetologia
, vol.40
, pp. 1172-1177
-
-
Shepherd, P.R.1
Nave, B.T.2
Rincon, J.3
Haigh, R.J.4
Foulstone, E.5
Proud, C.6
Zierath, J.R.7
Siddle, K.8
Wallberg-Henriksson, H.9
-
58
-
-
25844456354
-
Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRbetaPV knock-in mouse
-
Siesser W.B., Cheng S.-y., and McDonald M.P. Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRbetaPV knock-in mouse. Psychopharmacology (Berl.) 181 (2005) 653-663
-
(2005)
Psychopharmacology (Berl.)
, vol.181
, pp. 653-663
-
-
Siesser, W.B.1
Cheng, S.-y.2
McDonald, M.P.3
-
59
-
-
0037142618
-
Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer
-
Silva J.M., Dominguez G., Gonzalez-Sancho J.M., Garcia J.M., Silva J., Garcia-Andrade C., Navarro A., Munoz A., and Bonilla F. Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer. Oncogene 21 (2002) 4307-4316
-
(2002)
Oncogene
, vol.21
, pp. 4307-4316
-
-
Silva, J.M.1
Dominguez, G.2
Gonzalez-Sancho, J.M.3
Garcia, J.M.4
Silva, J.5
Garcia-Andrade, C.6
Navarro, A.7
Munoz, A.8
Bonilla, F.9
-
60
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck P.A., Pershouse M.A., Jasser S.A., Yung W.K., Lin H., Ligon A.H., Langford L.A., Baumgard M.L., Hattier T., Davis T., Frye C., Hu R., Swedlund B., Teng D.H., and Tavtigian S.V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15 (1997) 356-362
-
(1997)
Nat. Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.14
Tavtigian, S.V.15
-
61
-
-
6444245375
-
Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis
-
Suzuki H., Willingham M.C., and Cheng S.-y. Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis. Thyroid 12 (2002) 963-969
-
(2002)
Thyroid
, vol.12
, pp. 963-969
-
-
Suzuki, H.1
Willingham, M.C.2
Cheng, S.-y.3
-
62
-
-
0033210703
-
The v-erbA oncogene
-
review
-
Thormeyer, D., Baniahmad, A., 1999, The v-erbA oncogene, Int. J. Mol. Med., 4, 351-8 (review).
-
(1999)
Int. J. Mol. Med
, vol.4
, pp. 351-358
-
-
Thormeyer, D.1
Baniahmad, A.2
-
63
-
-
33847298591
-
Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion
-
Vasko V., Espinosa A.V., Scouten W., He H., Auer H., Liyanarachchi S., Larin A., Savchenko V., Francis G.L., de la Chapelle A., Saji M., and Ringel M.D. Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 2803-2808
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 2803-2808
-
-
Vasko, V.1
Espinosa, A.V.2
Scouten, W.3
He, H.4
Auer, H.5
Liyanarachchi, S.6
Larin, A.7
Savchenko, V.8
Francis, G.L.9
de la Chapelle, A.10
Saji, M.11
Ringel, M.D.12
-
64
-
-
33847662364
-
Thyroid hormone receptor TRbeta1 mediates Akt activation by T3 in pancreatic beta cells
-
Verga Falzacappa C., Petrucci E., Patriarca V., Michienzi S., Stigliano A., Brunetti E., Toscano V., and Misiti S. Thyroid hormone receptor TRbeta1 mediates Akt activation by T3 in pancreatic beta cells. J. Mol. Endocrinol. 38 (2007) 221-233
-
(2007)
J. Mol. Endocrinol.
, vol.38
, pp. 221-233
-
-
Verga Falzacappa, C.1
Petrucci, E.2
Patriarca, V.3
Michienzi, S.4
Stigliano, A.5
Brunetti, E.6
Toscano, V.7
Misiti, S.8
-
65
-
-
0027082349
-
Expression of the thyroid hormone receptor, the oncogenes c-myc and H-ras, and the 90 kD heat shock protein in normal, hyperplastic, and neoplastic human thyroid tissue
-
Wallin G., Bronnegard M., Grimelius L., McGuire J., and Torring O. Expression of the thyroid hormone receptor, the oncogenes c-myc and H-ras, and the 90 kD heat shock protein in normal, hyperplastic, and neoplastic human thyroid tissue. Thyroid 2 (1992) 307-313
-
(1992)
Thyroid
, vol.2
, pp. 307-313
-
-
Wallin, G.1
Bronnegard, M.2
Grimelius, L.3
McGuire, J.4
Torring, O.5
-
67
-
-
15044338824
-
Phosphoinositide 3-kinase in disease: timing, location, and scaffolding
-
Wymann M.P., and Marone R. Phosphoinositide 3-kinase in disease: timing, location, and scaffolding. Curr. Opin. Cell. Biol. 17 (2005) 141-149
-
(2005)
Curr. Opin. Cell. Biol.
, vol.17
, pp. 141-149
-
-
Wymann, M.P.1
Marone, R.2
-
68
-
-
0043032524
-
Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway
-
Xiao J.H., Ghosn C., Hinchman C., Forbes C., Wang J., Snider N., Cordrey A., Zhao Y., and Chandraratna R.A. Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway. J. Biol. Chem. 278 (2003) 29954-29962
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29954-29962
-
-
Xiao, J.H.1
Ghosn, C.2
Hinchman, C.3
Forbes, C.4
Wang, J.5
Snider, N.6
Cordrey, A.7
Zhao, Y.8
Chandraratna, R.A.9
-
69
-
-
0034964207
-
Physiological and molecular basis of thyroid hormone action
-
Yen P.M. Physiological and molecular basis of thyroid hormone action. Physiol. Rev. 81 (2001) 1097-1142
-
(2001)
Physiol. Rev.
, vol.81
, pp. 1097-1142
-
-
Yen, P.M.1
-
70
-
-
0042335979
-
Molecular basis of resistance to thyroid hormone
-
Yen P.M. Molecular basis of resistance to thyroid hormone. Trends Endocrinol. Metab. 14 (2003) 327-333
-
(2003)
Trends Endocrinol. Metab.
, vol.14
, pp. 327-333
-
-
Yen, P.M.1
-
71
-
-
33750592404
-
Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression
-
Ying H., Furuya F., Zhao L., Araki O., West B.L., Hanover J.A., Willingham M.C., and Cheng S.-y. Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression. J. Clin. Invest. 116 (2006) 2972-2984
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2972-2984
-
-
Ying, H.1
Furuya, F.2
Zhao, L.3
Araki, O.4
West, B.L.5
Hanover, J.A.6
Willingham, M.C.7
Cheng, S.-y.8
-
72
-
-
0141479958
-
Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma
-
Ying H., Suzuki H., Furumoto H., Walker R., Meltzer P., Willingham M.C., and Cheng S.y. Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma. Carcinogenesis 24 (2003) 1467-1479
-
(2003)
Carcinogenesis
, vol.24
, pp. 1467-1479
-
-
Ying, H.1
Suzuki, H.2
Furumoto, H.3
Walker, R.4
Meltzer, P.5
Willingham, M.C.6
Cheng, S.y.7
-
73
-
-
0034711271
-
Pituitary tumor transforming gene causes aneuploidy and p53-dependent and p53-independent apoptosis
-
Yu R., Heaney A.P., Lu W., Chen J., and Melmed S. Pituitary tumor transforming gene causes aneuploidy and p53-dependent and p53-independent apoptosis. J. Biol. Chem. 275 (2000) 36502-36505
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36502-36505
-
-
Yu, R.1
Heaney, A.P.2
Lu, W.3
Chen, J.4
Melmed, S.5
-
74
-
-
0034981804
-
Oncogene activation in pituitary tumors
-
Yu R., and Melmed S. Oncogene activation in pituitary tumors. Brain Pathol. 11 (2001) 328-341
-
(2001)
Brain Pathol.
, vol.11
, pp. 328-341
-
-
Yu, R.1
Melmed, S.2
-
75
-
-
0033018670
-
Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas
-
Zhang X., Horwitz G.A., Heaney A.P., Nakashima M., Prezant T.R., Bronstein M.D., and Melmed S. Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas. J. Clin. Endocrinol. Metab. 84 (1999) 761-767
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 761-767
-
-
Zhang, X.1
Horwitz, G.A.2
Heaney, A.P.3
Nakashima, M.4
Prezant, T.R.5
Bronstein, M.D.6
Melmed, S.7
-
76
-
-
23644435799
-
Chromosomal aberrations in cell lines derived from thyroid tumors spontaneously developed in TRbetaPV/PV mice
-
Zimonjic D.B., Kato Y., Ying H., Popescu N.C., and Cheng S.-y. Chromosomal aberrations in cell lines derived from thyroid tumors spontaneously developed in TRbetaPV/PV mice. Cancer Genet. Cytogenet. 161 (2005) 104-109
-
(2005)
Cancer Genet. Cytogenet.
, vol.161
, pp. 104-109
-
-
Zimonjic, D.B.1
Kato, Y.2
Ying, H.3
Popescu, N.C.4
Cheng, S.-y.5
-
77
-
-
0033575347
-
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
-
Zou H., McGarry T.J., Bernal T., and Kirschner M.W. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science 285 (1999) 418-422
-
(1999)
Science
, vol.285
, pp. 418-422
-
-
Zou, H.1
McGarry, T.J.2
Bernal, T.3
Kirschner, M.W.4
|