Mechanisms of thiosulfinates from Allium tuberosum L.-induced apoptosis in HT-29 human colon cancer cells

Toxicology Letters

Volumn 188, Issue 2, 2009, Pages 142-147

  Lee, Ju Hye ^a   Yang, Hee Sun ^b   Park, Kyoung Wuk ^b   Kim, Jae Yong ^c   Lee, Mi Kyung ^b   Jeong, Il Yun ^d   Shim, Ki Hwan ^e   Kim, Young Sook ^f   Yamada, Koji ^a   Seo, Kwon Il ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b Sunchon National University   (South Korea)

^c Kyungpook National University   (South Korea)

^d Korea Atomic Energy Research Institute   (South Korea)

^e Gyeongsang National University   (South Korea)

^f KT and G Corporation   (South Korea)

Author keywords

Allium tuberosum L.; Apoptosis; HT 29; Thiosulfinates

Indexed keywords

ALLOGRAFT INFLAMMATORY FACTOR 1; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; SULFINIC ACID DERIVATIVE;

ALLIUM TUBEROSUM; APOPTOSIS; ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL STRAIN HT29; CHROMATIN CONDENSATION; COLON CANCER; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; GARLIC; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UPREGULATION;

ANTICARCINOGENIC AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; CASPASES, EFFECTOR; CASPASES, INITIATOR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHIVE; COLONIC NEOPLASMS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFINIC ACIDS; TIME FACTORS;

ALLIUM TUBEROSUM;

EID: 67349249104     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.03.025     Document Type: Article

References (30)

1. Ashe P.C., and Berry M.D. Apoptotic signaling cascades. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 199-214
2. Block E. The organosulfur chemistry of the Genus Allium-implication for the organic chemistry of sulfur. Angew. Chem. Int. Ed. Engl. 31 (1992) 1135-1178
3. Block G., Patterson B., and Subar A. Fruit, vegetable, and cancer prevention: a review of the epidemiological evidence. Nutr. Cancer 18 (1992) 1-29
4. Evan G.I., and Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature 411 (2001) 342-348
5. Haenszel W., Locke F.B., Segi M., Kurihara M., and Locke F. Large bowel cancer Hawaiian Japanese. J. Natl. Cancer Inst. 51 (1973) 1765-1779
6. Haenszel W., Locke F.B., and Segi M. A case-control study of large bowel cancer in Japan. J. Natl. Cancer Inst. 64 (1980) 17-22
7. Kang Y.H., Yi M.J., Kim M.J., Park M.T., Bae S.W., Kang C.M., Cho C.K., Park I.C., Park M.J., Rhee C.H., Hong S.I., Chung H.Y., Lee Y.S., and Lee S.J. Caspase-independent cell death by arsenic trioxide in human cervical cancer cells; reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res. 64 (2004) 8960-8967
8. Kendler B.S. Garlic (Allium sativum) and onion (Allium cepa): a review of their relationship to cardiovascular disease. Prev. Med. 16 (1987) 670-685
9. Kelloff G.J., Crowell J.A., Steele V.E., Lubet R.A., Malone W.A., Boone C.W., Kopelovich L., Hawk E.T., Lieberman R., Lawrence J.A., Ali I., Viner J.L., and Siqman C.C. Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. J. Nutr. 130 (2000) 467-471
10. Kim E.J., Lee Y.J., Shin H.K., and Park J.H. Induction of apoptosis by the aqueous of Rubus coreanum in HT-29 human colon cancer cells. Nutrition 21 (2005) 1141-1148
11. Kuo P.L., Hsu Y.L., Chang C.H., and Lin C.C. The mechanism of ellipticine-induced apoptosis and cell cycle arrest in human breast MCF-7 cancer cells. Cancer Lett. 223 (2005) 293-301
12. Lau B.H.S., Tadi P.P., and Tosk J.M. Allium sativum (garlic) and caner prevention. Nutr. Res. 10 (1990) 937-948
13. Li H., Zhu H., Xu C.J., and Yuan J. Cleavage of Bid by caspase-8 mediated mitochondrial damage in the Fas pathway of apoptosis. Cell 94 (1998) 491-501
14. Meyskens F.L., and Szabo E. Diet and cancer: the disconnect between epidemiology and randomized clinical trials. Cancer Epidemiol. Biomarkers Prev. 14 (2005) 1369-11369
15. Morimitsu Y., Morioka Y., and Kawakishi S. Inhibitor of platelet aggregation generated from mixtures of Allium species and/or S-alk(en)yl-l-cysteine sulfoxide. J. Agric. Food Chem. 40 (1992) 368-372
16. Nagata S. Apoptotic DNA fragmentation. Exp. Cell Res. 256 (2000) 12
17. Nicholson D.W., Ali A., Thormberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., and Lazebnik Y.A. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376 (1995) 37-43
18. Oliver F.J., de la Rubia G., Rolli V., Ruiz-Ruiz M.C., de Murcia G., and Murcia J.M. Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis: lesson from an uncleavable mutant. J. Biol. Chem. 273 (1998) 33533-33539
19. Park K.W., Kim S.Y., Jeong I.L., Byun M.W., Park K.H., Yamada K., and Seo K.I. Cytotoxic and antitumor activities of thiosulfinates from Allium tuberosum L. J. Agric. Food Chem. 55 (2007) 7957-7961
20. Park S.Y., Cho S.J., Kwon H.C., Lee K.R., Rhee D.K., and Pyo S. Caspase-indepenednt cell death by allicin in human epithelial carcinoma cells: involvement of PKA. Cancer Lett. 224 (2005) 123-132
21. Ricote M., García-Tuñón I., Fraile B., Fernández C., Aller P., Paniagua1 R., and Royuela M. P38 MAPK protects against TNF-α-provoked apoptosis in LNCaP prostatic cancer cells. Apoptosis 11 (2006) 1969-1975
22. Saraste A., and Pulkki K. Morphologic and biochemical hallmarks of apoptosis. Cardiovasc. Res. 45 (2000) 528-537
23. Satoh M.S., and Lindahl T. Role of poly(ADP-ribose) formation in DNA repair. Nature 356 (1992) 356-358
24. Seo K.I., Moon Y.H., Choi S.U., and Park K.H. Antibacterial activity of S-metyl methanthiosulfinate and S-methyl 2-propene-1-thiosulfinate from chinese chive toward Escherichia coli O157:H7. Biosci. Biotechnol. Biochem. 65 (2001) 966-968
25. Su J.L., Lin M.T., Hong C.C., Chan C.C., Shiah S.G., Wu C.W., Chen S.T., Chau Y.P., and Kuo M.L. Resveratrol induces FasL-related apoptosis through Cdc42 activation of ASK1/JNK-dependent signaling pathway in human leukemia HL-60 cells. Carcinogenesis 26 (2005) 1-10
26. Tuyns A.J., Kaks R., and Haelterman M. Colorectal cancer and the consumption of foods: a case-control study in Belgium. Nutr. Cancer 11 (1998) 189-204
27. Volate S.R., Davenport D.M., Muga J., and Wargovich M.J. Modulation of aberrabnt crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin). Carcinogenesis 26 (2005) 1450-1456
28. Wan C.K., Wang C., Cheung H.Y., Yang M.S., and Fong W.F. Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-dependent HL-60 cells. Cancer Lett. 241 (2005) 1-11
29. Yang G.Y., Lio J., Kim K., Yurkow E.J., and Yang C.S. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenol. Carcinogenesis 19 (1998) 611-616
30. Yoshimoto M., Okuno S., Suwa S.T., and Yamakawa O. Effect of harvest time on nutrient content of sweet potato leaves. 12th Symposium of the International Society of Tropical Root Crops (2002) 312-323