Hyaluronan promotes the chondrocyte response to BMP-7

Osteoarthritis and Cartilage

Volumn 17, Issue 7, 2009, Pages 906-916

  Andhare, R A ^a,b   Takahashi, N ^c   Knudson, W ^c   Knudson, C B ^a,c  

^a RUSH MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c EAST CAROLINA UNIVERSITY   (United States)

Author keywords

BMP 7; CD44; Chondrocyte; Hyaluronan; TGF

Indexed keywords

HERMES ANTIGEN; HYALURONIC ACID; HYALURONIDASE; LUCIFERASE; OSTEOGENIC PROTEIN 1; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; HYALURONOGLUCOSAMINIDASE; SMAD PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL INTERACTION; CELL ISOLATION; CONTROLLED STUDY; COW; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANIMAL; CATTLE; CELL CULTURE; CELL SHAPE; DRUG EFFECT; FORELIMB; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD44; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEIN 7; CARPUS, ANIMAL; CARTILAGE, ARTICULAR; CATTLE; CELL SHAPE; CELLS, CULTURED; CHONDROCYTES; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; LUCIFERASES; PHOSPHORYLATION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 67349245451     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2008.12.007     Document Type: Article

References (44)

1. Hardingham T.E., and Fosang A.J. Proteoglycans: many forms and many functions. FASEB J 6 (1992) 861-870
2. Knudson W., and Knudson C. An update on hyaluronan and CD44 in cartilage. Curr Opin Orthop 15 (2004) 369-375
3. Knudson C.B., and Knudson W. Hyaluronan-binding proteins in development, tissue homeostasis and disease. FASEB J 7 (1993) 1233-1241
4. Nishida Y., Knudson C.B., Nietfeld J.J., Margulis A., and Knudson W. Antisense inhibition of hyaluronan synthase-2 in human articular chondrocytes inhibits proteoglycan retention and matrix assembly. J Biol Chem 274 (1999) 21893-21899
5. Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer 4 (2004) 528-539
6. Turley E.A., Noble P.W., and Bourguignon L.Y. Signaling properties of hyaluronan receptors. J Biol Chem 277 (2002) 4589-4592
7. Reddi A.H. Cartilage morphogenetic proteins: role in joint development, homoeostasis, and regeneration. Ann Rheum Dis 62 Suppl. 2 (2003) ii73-ii78
8. Chubinskaya S., and Kuettner K.E. Regulation of osteogenic proteins by chondrocytes. Int J Biochem Cell Biol 35 (2003) 1323-1340
9. Nishida Y., Knudson C.B., Kuettner K.E., and Knudson W. Osteogenic protein-1 promotes the synthesis and retention of extracellular matrix within bovine articular cartilage and chondrocyte cultures. Osteoarthritis Cartilage 8 (2000) 127-136
10. Nishida Y., Knudson C.B., Eger W., Kuettner K.E., and Knudson W. Osteogenic protein-1 stimulates cell-associated matrix assembly by normal human articular chondrocytes. Arthritis Rheum 43 (2000) 206-214
11. Flechtenmacher J., Huch K., Thonar E.J.M.A., Mollenhauer J., Davies S.R., Schmid T.M., et al. Recombinant human osteogenic protein 1 is a potent stimulator of the synthesis of cartilage proteoglycans and collagens by human articular chondrocytes. Arthritis Rheum 39 (1996) 478-488
12. Greenwald J., Groppe J., Gray P., Wiater E., Kwiatkowski W., Vale W., et al. The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Mol Cell 11 (2003) 605-617
13. Miyazono K., Maeda S., and Imamura T. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev 16 (2005) 251-263
14. Macias-Silva M., Hoodless P.A., Tang S.J., Buchwald M., and Wrana J.L. Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J Biol Chem 273 (1998) 25628-25636
15. Ebisawa T., Tada K., Kitajima I., Tojo K., Sampath T.K., Kawabata M., et al. Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation. J Cell Sci 112 (1999) 3519-3527
16. Gazzerro E., and Canalis E. Bone morphogenetic proteins and their antagonists. Rev Endocr Metab Disord 7 (2006) 51-65
17. Itoh S., and ten Dijke P. Negative regulation of TGF-beta receptor/Smad signal transduction. Curr Opin Cell Biol 19 (2007) 176-184
18. Peterson R.S., Andhare R.A., Rousche K.T., Knudson W., Wang W., Grossfield J.B., et al. CD44 modulates Smad1 activation in the BMP-7 signaling pathway. J Cell Biol 166 (2004) 1081-1091
19. Knudson C.B., Nofal G.A., Pamintuan L., and Aguiar D.J. The chondrocyte pericellular matrix: a model for hyaluronan-mediated cell-matrix interactions. Biochem Soc Trans 27 (1999) 142-147
20. Chow G., Knudson C.B., Homandberg G., and Knudson W. Increased expression of CD44 in bovine articular chondrocytes by catabolic cellular mediators. J Biol Chem 270 (1995) 27734-27741
21. Maltzman J.S., Carman J.A., and Monroe J.G. Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes. Mol Cell Biol 16 (1996) 2283-2294
22. Fitzgerald K.A., and O'Neill L.A. Characterization of CD44 induction by IL-1: a critical role for Egr-1. J Immunol 162 (1999) 4920-4927
23. Simpson M.A., Wilson C.M., Furcht L.T., Spicer A.P., Oegema Jr. T.R., and McCarthy J.B. Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells. J Biol Chem 277 (2002) 10050-10057
24. Ohno S., Im H.J., Knudson C.B., and Knudson W. Hyaluronan oligosaccharide-induced activation of transcription factors in bovine articular chondrocytes. Arthritis Rheum 52 (2005) 800-809
25. Iacob S., and Knudson C.B. Hyaluronan fragments activate nitric oxide synthase and the production of nitric oxide by articular chondrocytes. Int J Biochem Cell Biol 38 (2006) 123-133
26. Ohno S., Im H.J., Knudson C.B., and Knudson W. Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes. J Biol Chem 281 (2006) 17952-17960
27. Kothapalli D., Flowers J., Xu T., Pure E., and Assoian R.K. Differential activation of ERK and Rac mediates the proliferative and anti-proliferative effects of hyaluronan and CD44. J Biol Chem (2008) 10.1074/jbc.M802934200
28. Pardali K., Kowanetz M., Heldin C.H., and Moustakas A. Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1). J Cell Physiol 204 (2005) 260-272
29. Thorne R.F., Legg J.W., and Isacke C.M. The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events. J Cell Sci 117 (2004) 373-380
30. Mori T., Kitano K., Terawaki S.I., Maesaki R., Fukami Y., and Hakoshima T. Structural basis for CD44 recognition by ERM proteins. J Biol Chem 283 (2008) 29602-29612
31. Runyan C.E., Schnaper H.W., and Poncelet A.C. The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells. J Biol Chem 280 (2005) 8300-8308
32. Chen Y.G., Wang Z., Ma J., Zhang L., and Lu Z. Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling. J Biol Chem 282 (2007) 9688-9695
33. Shi W., Chang C., Nie S., Xie S., Wan M., and Cao X. Endofin acts as a Smad anchor for receptor activation in BMP signaling. J Cell Sci 120 (2007) 1216-1224
34. Ye L., Lewis-Russell J.M., Kynaston H., and Jiang W.G. Endogenous bone morphogenetic protein-7 controls the motility of prostate cancer cells through regulation of bone morphogenetic protein antagonists. J Urol 178 (2007) 1086-1091
35. Lin J., Patel S.R., Wang M., and Dressler G.R. The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia. Mol Cell Biol 26 (2006) 4577-4585
36. Takada T., Katagiri T., Ifuku M., Morimura N., Kobayashi M., Hasegawa K., et al. Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. J Biol Chem 278 (2003) 43229-43235
37. Irie A., Habuchi H., Kimata K., and Sanai Y. Heparan sulfate is required for bone morphogenetic protein-7 signaling. Biochem Biophys Res Commun 308 (2003) 858-865
38. Paine-Saunders S., Viviano B.L., Economides A.N., and Saunders S. Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients. J Biol Chem 277 (2002) 2089-2096
39. Niikura T., and Reddi A.H. Differential regulation of lubricin/superficial zone protein by transforming growth factor beta/bone morphogenetic protein superfamily members in articular chondrocytes and synoviocytes. Arthritis Rheum 56 (2007) 2312-2321
40. Shintani N., and Hunziker E.B. Chondrogenic differentiation of bovine synovium: bone morphogenetic proteins 2 and 7 and transforming growth factor beta1 induce the formation of different types of cartilaginous tissue. Arthritis Rheum 56 (2007) 1869-1879
41. Li T.-F., Darowish M., Zuscik M.J., Chen D., Schwarz E.M., Rosier R.N., et al. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. J Bone Miner Res 21 (2006) 4-16
42. Homandberg G., Meyers R., and Xie D.L. Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture. J Biol Chem 267 (1992) 3597-3604
43. Knudson W., Casey B., Nishida Y., Eger W., Kuettner K.E., and Knudson C.B. Hyaluronan oligosaccharides perturb cartilage matrix homeostasis and induce chondrogenic chondrolysis. Arthritis Rheum 43 (2000) 1165-1174
44. Nagano O., and Saya H. Mechanism and biological significance of CD44 cleavage. Cancer Sci 95 (2004) 930-935