The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecting loss of quiescence

Leukemia

Volumn 23, Issue 5, 2009, Pages 892-899

  Bruns, I ^a   Czibere, A ^a   Fischer, J C ^a   Roels, F ^b   Cadeddu, R P ^a   Buest, S ^a   Bruennert, D ^a   Huenerlituerkoglu, A N ^c   Stoecklein, N H ^a   Singh, R ^a   Zerbini, L F ^d   Jager M ^a   Kobbe, G ^a   Gattermann, N ^a   Kronenwett, R ^a   Brors, B ^b   Haas, R ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c Lukaskrankenhaus GmbH   (Germany)

^d HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN 2-3 COMPLEX; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ACTIVATING TRANSCRIPTION FACTOR 1; CADHERIN; CADHERIN 2; CD164 ANTIGEN; CD53 ANTIGEN; CELL ADHESION MOLECULE; CELL NUCLEUS RECEPTOR; CHEMOKINE RECEPTOR CXCR4; FIBRONECTIN; GAMMA ACTIN 1; HERMES ANTIGEN; INSULIN RECEPTOR; INTERLEUKIN 8; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 11; KRUPPEL LIKE FACTOR 2; L SELECTIN; NUCLEUS RECEPTOR 4; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHODIESTERASE IV; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 4; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LIKE 5; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; CD34 SELECTION; CELL ADHESION; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL MIGRATION; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ERYTHROCYTE; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MEGAKARYOCYTE; MYELOID PROGENITOR CELL; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROGENY; SEQUENCE HOMOLOGY; STEM CELL EXPANSION; T LYMPHOCYTE SUBPOPULATION;

EID: 67349244371     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.392     Document Type: Article

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