BCR/ABL-mediated downregulation of genes implicated in cell adhesion and motility leads to impaired migration toward CCR7 ligands CCL19 and CCL21 in primary BCR/ABL-positive cells

Leukemia

Volumn 19, Issue 3, 2005, Pages 373-380

  Jongen Lavrencic, M ^a,b   Salesse, S ^a   Delwel, R ^b   Verfaillie, C M ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Adhesion; BCR ABL; CML; Gene expression; Migration

Indexed keywords

BCR ABL PROTEIN; CHEMOKINE RECEPTOR CCR7; COMPLEMENTARY DNA; ENHANCED GREEN FLUORESCENT PROTEIN; IMATINIB; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; SECONDARY LYMPHOID TISSUE CHEMOKINE; BETA CHEMOKINE; CC CHEMOKINE RECEPTOR 7; CHEMOKINE RECEPTOR; LIGAND; MESSENGER RNA;

ARTICLE; BONE MARROW; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DNA LIBRARY; DOWN REGULATION; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; LEUKEMOGENESIS; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UMBILICAL CORD BLOOD; CELL LINE; CELL MOTION; CELL STRAIN K 562; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; PHYSIOLOGY;

CELL ADHESION; CELL LINE; CELL MOVEMENT; CHEMOKINES, CC; DOWN-REGULATION; FUSION PROTEINS, BCR-ABL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; K562 CELLS; L-SELECTIN; LEUKEMIA, MYELOID, CHRONIC; LIGANDS; RECEPTORS, CHEMOKINE; RNA, MESSENGER;

EID: 15044352222     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403626     Document Type: Article

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