Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (danio rerio) lateral line and mouse (mus musculus) utricle

JARO - Journal of the Association for Research in Otolaryngology

Volumn 10, Issue 2, 2009, Pages 191-203

  Ou, Henry C ^a,b,c   Cunningham, Lisa L ^d   Francis, Shimon P ^d   Brandon, Carlene S ^d   Simon, Julian A ^e   Raible, David W ^a   Rubel, Edwin W ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Seattle Children's Hospital   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^e Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Aminoglycoside; FDA library; Hair cell; Ototoxicity; Protection; Zebrafish

Indexed keywords

AMINOGLYCOSIDE; GENTAMICIN; NEOMYCIN; TACRINE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG APPROVAL; DRUG COMBINATION; DRUG SCREENING; DRUG UPTAKE; EMBRYO; FOOD AND DRUG ADMINISTRATION; HAIR CELL; INNER EAR; LATERAL LINE SYSTEM; MALE; MOUSE; NEUROMODULATION; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; UTRICLE; ZEBRA FISH;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL SURVIVAL; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HAIR CELLS, AUDITORY; LATERAL LINE SYSTEM; MALE; MECHANOTRANSDUCTION, CELLULAR; MICE; NEOMYCIN; PHARMACEUTICAL PREPARATIONS; SACCULE AND UTRICLE; TACRINE; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION; ZEBRAFISH;

EID: 67349234898     PISSN: 15253961     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10162-009-0158-y     Document Type: Article

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