Biodosimetry using micronucleus assay in acute partial body therapeutic irradiation

Physica Medica

Volumn 25, Issue 2, 2009, Pages 82-87

  Senthamizhchelvan, Srinivasan ^a   Pant, G S ^a   Rath, G K ^a   Julka, P K ^a   Nair, O ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Biodosimetry; Cancer patients; Micronucleus; Peripheral blood lymphocytes

Indexed keywords

ADULT; ARTICLE; CALIBRATION; CANCER PATIENT; CLINICAL ARTICLE; DOSIMETRY; FEMALE; HUMAN; IN VITRO STUDY; IONIZING RADIATION; IRRADIATION; MALE; MICRONUCLEUS TEST; RADIATION DOSE; RADIATION EXPOSURE;

ADULT; BIOLOGICAL ASSAY; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; MALE; MICRONUCLEUS TESTS; MIDDLE AGED; RADIOMETRY; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 67349200933     PISSN: 11201797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmp.2008.05.004     Document Type: Article

References (45)

1. Baranov A.E., Guskova A.K., Nadejina N.M., and Nugis V.Y. Chernobyl experience: biological indicators of exposure to ionizing radiation. Stem Cells 13 (1995) 69-77
2. Ramalho A.T., Nascimento A.C.H., and Natarajan A.T. Dose assessments by cytogenetic analysis in the Goiania (Brazil) radiation accident. Radiat Prot Dosimetry 25 (1988) 97-100
3. 60 Co radiation accident: cytogenetic dosimetry and follow-up evaluations in three accident victims. Radiat Prot Dosimetry 35 (1991) 115-123
4. Bauchinger M. Cytogenetic research after accidental radiation exposure. Stem Cells 3 (1995) 182-190
5. Natarajan A.T. Chromosome aberrations: past, present and future. Mutat Res 504 (2002) 3-16
6. Countryman P.I., and Heddle J.A. The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutat Res 41 (1976) 321-331
7. Albertini R.J., Anderson D., Douglas G.R., Hagmar L., Hemmink K., Merlo F., et al. IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. International program on chemical safety. Mutat Res 463 (2000) 111-172
8. Fenech M. Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death. Mutat Res 600 (2006) 58-66
9. Bonassi S., Znaor A., Ceppi M., Lando C., Chang W.P., Holland N., et al. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis 28 (2007) 625-631
10. Lee T.K., O'Brien K.F., Naves J.L., Christie K.I., Arastu H.H., Eaves G.S., et al. Micronuclei in lymphocytes of prostate cancer patients undergoing radiation therapy. Mutat Res 469 (2000) 63-70
11. Thierens H., Vral A., Van Eijkeren M., Spelman F., and de Riddle L. Micronucleus induction in peripheral blood lymphocytes of patients under radiotherapy treatment for cervical cancer or Hodgkin's disease. Int J Radiat Biol 67 (1995) 529-539
12. Venkatachalam P., Solomon F.D., Prabhu B.K., Mohankumar M.N., Gajendiran N., and Jeevanram R.K. Estimation of dose in cancer patients treated with fractionated radiotherapy using translocation, dicentrics and micronuclei frequency in peripheral blood lymphocytes. Mutat Res 429 (1999) 1-12
13. Wojcik A., Stephan G., Sommer S., Buraczewska I., Kuszewski T., Wieczorek A., et al. Chromosomal aberrations and micronuclei in lymphocytes of breast cancer patients after an accident during radiotherapy with 8 MeV electrons. Radiat Res 160 (2003) 677-683
14. Catena C., Conti D., Parasacchi P., Marenco P., Bortolato B., Botturi M., et al. Micronuclei in cytokinesis-blocked lymphocytes may predict patient response to radiotherapy. Int J Radiat Biol 70 (1996) 301-308
15. Widel M., Jedrus S., Owczarek S., Konopacka M., Lubecka B., and Kolosza Z. The increment of micronucleus frequency in cervical carcinoma during irradiation in vivo and its prognostic value for tumour radiocurability. Br J Cancer 80 (1999) 1599-1607
16. Widel M., Kolosza Z., Jedrus S., Lukaszczyk B., Raczek-Zwierzycka K., and Swierniak A. Micronucleus assay in vivo provides significant prognostic information in human cervical carcinoma; the updated analysis. Int J Radiat Biol 7 (2001) 631-636
17. Widel M., Jedrus S., Lukaszczyk B., Raczek-Zwierzycka K., and Swierniak A. Radiation-induced micronucleus frequency in peripheral blood lymphocytes is correlated with normal tissue damage in patients with cervical carcinoma undergoing radiotherapy. Radiat Res 159 (2003) 713-721
18. Jagetia G.C., Jayakrishnan A., Fernandes D., and Vidyasagar M.S. Evaluation of micronuclei frequency in the cultured peripheral blood lymphocytes of cancer patients before and after radiation treatment. Mutat Res 491 (2001) 9-16
19. Jianlin L., Jiliang H., Lifen J., Wei Z., Baohong W., and Hongping D. Measuring the genetic damage in cancer patients during radiotherapy with three genetic end-points. Mutagenesis 19 (2004) 457-464
20. Fenech M., Denham J., Francis W., and Morley A. Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int J Radiat Biol 57 (1990) 373-383
21. Gantenberg H.W., Wuttke K., Streffer C., and Muller W.U. Micronuclei in human lymphocytes irradiated in vitro or in vivo. Radiat Res 128 (1991) 276-281
22. Silva-Barbosa I., Pereira-Magnata S., Amaral A., Sotero G., and Melo H.C. Dose assessment by quantification of chromosome aberrations and micronuclei in peripheral blood lymphocytes from patients exposed to gamma radiation. Genet Mol Biol 28 (2005) 452-457
23. 131I-MIBG therapy for neuroblastoma and carcinoid tumors. Nucl Med Commun 22 (2001) 367-374
24. Erselcan T., Sungu S., Ozdemir S., Turgut B., Dogan D., and Ozdemir O. Iodine-131 treatment and chromosomal damage: in vivo dose-effect relationship. Eur J Nucl Med Mol Imaging 31 (2004) 676-684
25. M'Kacher R., Legal J.D., Schlumberger M., Voisin P., Aubert B., Gaiilard N., et al. Biologic dosimetry in patients treated with iodine-131 for differentiated thyroid carcinoma. J Nucl Med 37 (1996) 1860-1864
26. Gutierrez S., Carbonell E., Galofre P., Creus A., and Marcos R. Cytogenetic damage after iodine-131 treatment for hyperthyroidism and thyroid cancer: a study using the micronuclei test. Eur J Nucl Med 26 (1999) 1589-1596
27. Monteiro O., Oliveira N.G., Rodrigues A.S., Laires A., Ferreira T.C., Limert E., et al. Alterations and oxidative stress in thyroid cancer patients after iodine-131 therapy. Mutagenesis 15 (2000) 69-75
28. Ballardin M., Gemignani F., Bodei L., Mariani G., Ferdeghini M., Rossi A.M., et al. Formation of micronuclei and of clastogenic factor(s) in patients receiving therapeutic doses of iodine-131. Mutat Res 514 (2002) 77-85
29. Grawe J., Biko J., Lorenz R., Reiners C., Stopper H., Vershenya S., et al. Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer. Mutat Res 583 (2005) 12-25
30. Kinashi Y., Sakurai Y., Masunaga S., Suzuki M., Nagata K., and Ono K. Evaluation of micronucleus induction in lymphocytes of patients following boron-neutron-capture-therapy: a comparison with thyroid cancer patients treated with radioiodine. J Radiat Res 48 (2007) 197-204
31. Song E.Y., Rizvi S.M., Qu C.F., Raja C., Yuen J., Li Y., et al. The cytokinesis-block micronucleus assay as a biological dosimeter for targeted alpha therapy. Phys Med Biol 53 (2008) 319-328
32. Urbanik W., Kukołowicz P., Kuszewski T., Gozdz S., and Wojcik A. Modelling the frequencies of chromosomal aberrations in peripheral lymphocytes of patients undergoing radiotherapy. Nukleonika 48 (2003) 3-8
33. Jones L.A., Scott D., Cowan R., and Roberts S.A. Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: chromosome aberrations after low dose-rate irradiation. Int J Radiat Biol 67 (1995) 519-528
34. Louagie H., Van Eijkeren M., Philippe J., Thierens H., and de Ridder L. Changes in peripheral blood lymphocyte subsets in patients undergoing radiotherapy. Int J Radiat Biol 75 (1999) 767-771
35. Taghavi-Dehaghani M., Mohammadi S., Ziafazeli T., and Sardari-Kermani M. A study on differences between radiation-induced micronuclei and apoptosis of lymphocytes in breast cancer patients after radiotherapy. Z Naturforsch C 60 (2005) 938-942
36. Savage J.R.K. Sites of radiation induced chromosome exchanges. Curr Top Radiat Res 6 (1970) 129-194
37. Senthamizhchelvan S., Pant G.S., Rath G.K., Julka P.K., Nair O., and Prabhakar R. Biological estimation of dose in hemi-body irradiation of cancer patients by cytogenetic analysis. Health Phys 94 (2008) 112-117
38. Dolphin G.W. Biological dosimetry with particular reference to chromosome aberration analysis. A review of methods (1969), International Atomic Energy Agency, Vienna 215-224
39. Matsubara S., Sasaki M.S., and Adachi T. Dose-response relationship of lymphocyte chromosome aberrations in locally irradiated persons. J Radiat Res 15 (1974) 189-196
40. Durante M., Yamada S., Ando K., Furusawa Y., Kawata T., Majima H., et al. Measurements of the equivalent whole-body dose during radiation therapy by cytogenetic methods. Phys Med Biol 44 (1999) 1289-1298
41. Durante M., Yamada S., Ando K., Furusawa Y., Kawata T., Majima H., et al. X-rays vs. carbon-ion tumor therapy: cytogenetic damage in lymphocytes. Int J Radiat Oncol Biol Phys 47 (2000) 793-798
42. d'Alesio V., Pacelli R., Durante M., Canale Cama G., Cella L., Gialanella G., et al. Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients. Int J Radiat Oncol Biol Phys 57 (2003) 732-738
43. Sreedevi B., Rao B.S., Nagaraj H., and Pal N.K. Chromosome aberration analysis in radiotherapy patients and simulated partial body exposures: biological dosimetry for non-uniform exposures. Radiat Prot Dosimetry 94 (2001) 317-322
44. Heimers A., Brede H.J., Giesen U., and Hoffmann W. Chromosome aberration analysis and the influence of mitotic delay after simulated partial-body exposure with high doses of sparsely and densely ionising radiation. Radiat Environ Biophys 45 (2006) 45-54
45. Senthamizhchelvan S., Pant G.S., Rath G.K., Julka P.K., Nair O., and Joshi R.C. Biodosimetry using chromosome aberrations in human lymphocytes. Radiat Prot Dosimetry 123 (2007) 241-245