Prion protein protects against zinc-mediated cytotoxicity by modifying intracellular exchangeable zinc and inducing metallothionein expression

Journal of Trace Elements in Medicine and Biology

Volumn 23, Issue 3, 2009, Pages 214-223

  Rachidi, Walid ^a   Chimienti, Fabrice ^b   Aouffen, M'hammed ^a   Senator, Abderrahmane ^c   Guiraud, Pascale ^c   Seve, Michel ^d   Favier, Alain ^a  

^a CEA GRENOBLE   (France)

^b INAC SCIB   (France)

^c Domaine de la Merci   (France)

^d INSTITUT ALBERT BONNIOT   (France)

Author keywords

Metallothionein; Neurodegeneration; Prion protein; Zinc ions

Indexed keywords

DOXYCYCLINE; METALLOTHIONEIN; PRION PROTEIN; ZINC; ZINC BINDING PROTEIN;

ABSORPTION SPECTROPHOTOMETRY; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; HOMEOSTASIS; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; CELL LINE; CELL SURVIVAL; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; METALLOTHIONEIN; MICE; PRPC PROTEINS; TRACE ELEMENTS; ZINC;

EID: 67349199718     PISSN: 0946672X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtemb.2009.02.007     Document Type: Article

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