Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease

Journal of Neural Transmission

Volumn 105, Issue 4-5, 1998, Pages 497-505

  Jimenez Jimenez F J ^a,d   Molina, J A ^b   Aguilar, M V ^b   Meseguer, I ^b   Mateos Vega, C J ^b   Gonzalez Munoz M J ^b   De Bustos, F ^c   Martinez Salio A ^b   Orti Pareja M ^a   Zurdo, M ^a   Martinez Para M C ^b  

^a HOSPITAL UNIVERSITARIO PRÍNCIPE DE ASTURIAS   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

^c HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^d NONE   (Spain)

Author keywords

Cerebrospinal fluid levels; Copper; Iron; Manganese; Parkinson's disease; Serum levels; Transition metals; Zinc

Indexed keywords

ANTIPARKINSON AGENT; COPPER; IRON; MANGANESE; METAL; ZINC;

ADULT; AGE; AGED; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; COPPER BLOOD LEVEL; DISEASE DURATION; FEMALE; HUMAN; IRON BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; ONSET AGE; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RATING SCALE; ZINC BLOOD LEVEL;

AGE OF ONSET; AGED; ANTIPARKINSON AGENTS; BLOOD PROTEINS; COPPER; DOPAMINE AGONISTS; FEMALE; HUMANS; IRON; LEVODOPA; MALE; MANGANESE; METALS, HEAVY; MIDDLE AGED; NUTRITIONAL STATUS; PARKINSON DISEASE; REFERENCE VALUES; SELEGILINE; SPECTROPHOTOMETRY, ATOMIC; TRACE ELEMENTS; VITAMIN A; ZINC;

EID: 14444272313     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050073     Document Type: Article

References (40)

1. Abbott RA, Cox M, Markus H, Tomkins A (1992) Diet, body size and micronutrient status in Parkinson's disease. Eur J Clin Nutr 46: 879-884
2. Ayuso-Peralta L, Jiménez-Jiménez FJ, Cabrera-Valdivia F, Molina JA, Rabasa M, Almazán J, Tabernero C, de Pedro-Cuesta J, Giménez-Roldán S (1997) Premorbid dietetic habits and risk for Parkinson's disease. Parkinsonism Rel Disord 3: 55-61
3. Cabrera-Valdivia F, Jiménez-Jiménez FJ, Molina JA, Férnandez-Calle P, Vázquez A, Cañizares-Liébana F, Larumbe-Lobalde S, Ayuso-Peralta L, Rabasa M, Codoceo R (1994) Peripheral iron metabolism in patients with Parkinson's disease. J Neurol Sci 125: 82-86
4. Campanella G, Carrieri P, Pasqual-Marsettin E, Romito D (1973) Ferro, transferrina, rame e ceruloplasmina del siero e del liquor nelle malattie extrapiramidali e nelle miopatie primitive. Acta Neurol (Napoli) 28: 1-34
5. Chen WH, Shin PY (1992) The serum ferrokinetics in Parkinson's disease. The serum ferrokinetics in Parkinson's disease. Kao Hsiung I Hsueh Ko Hsueh Tsah Chin 8: 581-584
6. Chvapil M (1976) Effect of zinc on cells and biomembranes. Med Clin North Am 60: 799-812
7. Dexter DT, Wells FR, Agid F, Agid Y, Lees AJ, Jenner P, Marsden CD (1987) Increased nigral iron content in postmortem parkinsonian brain. Lancet ii: 1219-1220
8. Dexter DT, Wells FR, Lees AJ, Agid F, Agid Y, Jenner P, Marsden CD (1989) Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J Neurochem 52: 1830-1836
9. Dexter DT, Carayon A, Vidailhet M, Ruberg M, Agid F, Agid Y, Lees AJ, Wells FR, Jenner P, Marsden CD (1990) Decreased ferritin levels in brain in Parkinson's disease. J Neurochem 55: 16-20
10. Dexter DT, Carayon A, Javoy-Agid F, Agid Y, Wells FR, Daniel SE, Lees AJ, Jenner P, Marsden CD (1991) Alterations in the levels of iron, ferritin, and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain 114: 1953-1975
11. Dexter DT, Jenner P, Schapira AH, Marsden CD (1992) Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases afecting the basal ganglia. The Royal Kings and Queens Parkinson's disease research group. Ann Neurol [Suppl]: S94-S100
12. Donaldson J, McGregor D, LaBella F (1982) Manganese neurotoxicity: a model for free radical mediated neurodegeneration? Can J Physiol Pharmacol 60: 1398-1405
13. Dormandy TL (1978) Free-radical oxidation and antioxidants. Lancet i: 647-650
14. Fahn S, Cohen G (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 32: 804-812
15. Fahn S, Elton RL, and members of the UPDRS Development Committee (1987) Unified Parkinson's Disease Rating Scale. In: Fahn S, Marsden CD, Goldstein M, Calne DB (eds) Recent developments in Parkinson's disease, vol 2. Florham Park, New Jersey, pp 153-163
16. Gazzaniga GC, Ferraro B, Camerlingo M, Casto L, Viscardi M, Mamoli A (1992) A case control study of CSF copper, iron, and manganese in Parkinson's disease. Ital J Neurol Sci 13: 239-243
17. Gerlach M, Ben-Sachar D, Riederer P, Youdim MBH (1994) Altered brain metabolism of iron as a cause of Parkinson's disease? J Neurochem 63: 793-807
18. Gorell JM, Johnson CC, Rybicki BA, Peterson EL, Kortsha GX, Brown GG, Richardson RJ (1997) Occupational exposures to metals as risk factors for Parkinson's disease. Neurology 48: 650-658
19. Halliwell B, Gutteridge JMC (1985) Oxigen-radicals and the nervous system. Trends Neurosci 8: 22-26
20. Halliwell B, Gutteridge JMC (1988) Iron as a biological pro-oxidant. ISI Atlas Sci Biochem 1: 48-52
21. Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17: 427-442
22. Hughes AJ, Ben-Shlomo SE, Daniel SE, Lees AJ (1992) What features improve the accuracy of clinical diagnosis in Parkinson's disease? A clinicopathological study. Neurology 42: 1142-1146
23. Jiménez-Jiménez FJ, Luquin MR (1996) Mecanismos de muerte neuronal y neuroprotección en la enfermedad de Parkinson. In: Luquin MR, Jiménez-Jiménez FJ, Martínez-Vila E, Molina-Arjona JA, Bermejo-Pareja F, Coria-Balanzat F (eds) Mecanismos de muerte neuronal y neuroprotección en enfermedades neurológicas. Neurología 11 [Suppl 3]: 93-106
24. Jiménez-Jiménez FJ, Fernández-Calle P, Martínez-Vanaclocha M, Herrero E, Molina JA, Vázquez A, Codoceo R (1992) Serum levels of zinc and copper in patients with Parkinson's disease. J Neurol Sci 112: 30-33
25. Jiménez-Jiménez FJ, Molina JA, Aguilar MV, Arrieta FJ, Jorge-Santamaría A, Cabrera-Valdivia F, Ayuso-Peralta L, Rabasa M, Vázquez A, García-Albea E, Martínez-Para C (1995) Serum and urinary manganese levels in patients with Parkinson's disease. Acta Neurol Scand 91: 317-320
26. Kuiper MA, Mulder C, van Kamp GJ, Scheltens P, Wolters EC (1994) Cerebrospinal fluid ferritin levels of patients with Parkinson's disease. Alzheimer's disease, and multiple system atrophy. J Neural Transm [Park Dis Dement Sect] 7: 109-114
27. Larsen NA, Pakkenberg H, Damsgaard E, Deydorm K, Wold S (1981) Distribution of arsenic, manganese, and selenium in the human brain in chronic renal insufficiency, Parkinson's disease, and amyotrophic lateral sclerosis. J Neurol Sci 51: 437-446
28. Loeffler DA, DeMaggio AJ, Juneau PL, Brickman CM, Mashour GA, Finkelman JH, Pomara N, LeWitt PA (1994) Ceruloplasmin is increased in cerebrospinal fluid in Alzheimer's disease but not Parkinson's disease. Alzheimer Dis Assoc Disord 8: 190-197
29. Logroscino G, Marder K, Graziano J, Freyer G, Slavkovich V, LoIacono N, Cote L, Mayeux R (1997) Altered systemic iron metabolism in Parkinson's disease. Neurology 49: 714-717
30. Marttila RJ, Lorentz H, Rinne UK (1988) Oxygen toxicity protecting enzymes in Parkinson's disease: increase of superoxide dismutase-like activity in the substantia nigra and basal nucleus. J Neurol Sci 86: 321-331
31. Meret S, Henkin RI (1971) Simultaneous direct estimation by atomic absorption spectrophotometry of copper and zinc in serum, urine, and cerebrospinal fluid. Clin Chem 17: 369-373
32. Moreu E, Molinero LM, Fernández E (1990) R-Sigma: Base de datos bioestadística para un ordenador personal. Horus Hardware, Madrid
33. Olson AD, Hamlin WB (1969) A new method for serum iron and total iron-binding capacity by atomic absorption spectrophotometry. Clin Chem 15: 438-444
34. Pall HS, Williams AC, Blake DR, Lunec J, Gutteridge JM, Hall M, Taylor A (1987) Raised cerebrospinal fluid copper concentration in Parkinson's disease. Lancet ii: 238-241
35. Pall HS, Brailsford S, Williams AC, Lunec J, Blake DR (1990) Ferritin in the cerebrospinal fluid of patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 53: 803
36. Pan BY, Cheng QL, He ZX, Su CC (1997) Transition metals in serum and CSF of patients with Parkinson's disease. Poster P125, XIIth International Symposium on Parkinson's disease, London, March 23-26. Mov Disord 12 [Suppl 1]: 33
37. Riederer P, Sofic E, Rausch WD, Schmidt B, Reynolds GP, Jellinger K, Youdim MBH (1989) Transition metals, ferritine, glutathione, and ascorbic acid in parkinsonian brains. J Neurochem 52: 515-520
38. Saggu H, Cooksey J, Dexter D, Wells FR, Lees A, Jenner P, Marsden CD (1989) A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra. J Neurochem 53: 692-697
39. Takahashi S, Takahashi J, Osawa N, Abe T, Yonezawa H, Sera K, Tohgi H (1994) Trace elements analysis of serum and cerebrospinal fluid with PIXE: effect of age and changes in parkinsonian patients. Nippon Ronen Igakkai Zasshi 31: 865-871
40. Uitti RJ, Rajput AH, Rozdilsky B, Bickis M, Wollin T, Yuen WK (1989) Regional metal concentrations in Parkinson's disease, other chronic neurological diseases, and control brains. Can J Neurol Sci 16: 310-314