Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells

Bone

Volumn 45, Issue 1, 2009, Pages 52-60

  Kazmers, Nikolas H ^a   Ma, Sophia A ^a   Yoshida, Tomohiko ^a   Stern, Paula H ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Bisphosphonate; Cytoskeleton; Osteoblast; Parathyroid hormone; RhoA

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALENDRONIC ACID; F ACTIN; GERANYLGERANIOL; GGTI 2166; PARATHYROID HORMONE[1-34]; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE REMODELING; CELL DENSITY; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; DRUG MECHANISM; FOCAL ADHESION; MOUSE; NONHUMAN; OSTEOBLAST; STRESS FIBER;

ACTINS; ALENDRONATE; ALKYL AND ARYL TRANSFERASES; AMIDES; ANIMALS; CATTLE; CELL LINE; CYTOSKELETON; DIPHOSPHONATES; DITERPENES; ENZYME INHIBITORS; FOCAL ADHESIONS; IMAGING, THREE-DIMENSIONAL; MICE; MODELS, BIOLOGICAL; OSTEOBLASTS; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PYRIDINES; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; STRESS FIBERS;

EID: 67349191592     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.03.675     Document Type: Article

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