PAR bZIP-bik is a novel transcriptional pathway that mediates oxidative stress-induced apoptosis in fibroblasts

Cell Death and Differentiation

Volumn 16, Issue 6, 2009, Pages 838-846

  Ritchie, A ^a   Gutierrez, O ^a   Fernandez Luna, J L ^a  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN D SITE BINDING PROTEIN; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; HEPATIC LEUKEMIA FACTOR; PROTEIN P53; THYROTROPH EMBRYONIC FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BIK; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; SURVIVAL RATE; TRANSCRIPTION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE, TUMOR; CELLS, CULTURED; DNA-BINDING PROTEINS; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; HUMANS; HYDROGEN PEROXIDE; MICE; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 67349187962     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.13     Document Type: Article

References (38)

1. Hunger SP, Ohyashiki K, Toyama K, Cleary ML. Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia. Genes Dev 1992; 6: 1608-1620.
2. Drolet DW, Scully KM, Simmons DM, Wegner M, Chu KT, Swanson LW et al TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. Genes Dev 1991; 5: 1739-1753.
3. Khatib ZA, Inaba T, Valentine M, Look AT. Chromosomal localization and cDNA cloning of the human DBP and TEF genes. Genomics 1994; 23 344-351.
4. Gachon F, Fonjallaz P, Damiola F, Gos P, Kodama T, Zakany J et al. The loss of circadian PAR bZip transcription factors results in epilepsy. Genes Dev 2004; 18: 1397-1412.
5. Gachon F, Olela FF, Schaad O, Descombes P, Schibler U. The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab 2006; 4: 25-36.
6. Benito A, Gutierrez O, Pipaon C, Real PJ, Gachon F, Ritchie AE et al A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. J Biol Chem 2006; 281: 38351-38357.
7. Bouillet P, Strasser A. BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J Cell Sci 2002; 115: 1567-1574.
8. Gelinas C, White E. BH3-only proteins in control: Specificity regulates MCL-1 and BAK-mediated apoptosis. Genes Dev 2005; 19: 1263-1268.
9. Strasser A. The role of BH3-only proteins in the immune system. Nat Rev Immunol 2005; 5: 189-200.
10. Guo B, Godzik A, Reed JC. Bcl-G, a novel pro-apoptotic member of the Bcl-2 family. J Biol Chem 2001; 276: 2780-2785.
11. Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 2005; 331: 851-858.
12. Akiyama T, Bouillet P, Miyazaki T, Kadono Y, Chikuda H, Chung UI et al. Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. EMBO J 2003; 22 6653-6664.
13. Puthalakath H, Strasser A. Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002; 9: 505-512.
14. del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997; 278: 687-689.
15. Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000; 288: 1053-1058.
16. Nakano K, Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 2001; 7: 683-694.
17. Mathai JP, Germain M, Marcellus RC, Shore GC. Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53. Oncogene 2002; 21: 2534-2544.
18. Michalak EM, Villunger A, Adams JM, Strasser A. In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ 2008; 15: 1019-1029.
19. Real PJ, Benito A, Cuevas J, Berciano MT, de Juan A, Coffer P et al Blockade of epidermal growth factor receptors chemosensitizes breast cancer cells through up-regulation of Bnip3L. Cancer Res 2005; 65: 8151-8157.
20. Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 2001; 61: 6669-6673.
21. Hershko T, Ginsberg D. Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J Biol Chem 2004; 279: 8627-8634.
22. Sanz C, Mellstrom B, Link W, Naranjo J, Fernandez-Luna J. Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells. EMBO J 2001; 20: 2286-2292.
23. Anantharam V, Lehrmann E, Kanthasamy A, Yang Y, Banerjee P, Becker KG et al. Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: Relevance to oxidative damage in Parkinson's disease. Neurochem Int 2007; 50: 834-847.
24. Gillissen B, Essmann F, Hemmati PG, Richter A, Oztop I, Chinnadurai G et al. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis. J Cell Biol 2007; 179: 701-715.
25. Resch U, Schichl YM, Sattler S, de Martin R. XIAP regulates intracellular ROS by enhancing antioxidant gene expression. Biochem Biophys Res Commun 2008; 375: 156-161.
26. Hur J, Chesnes J, Coser KR, Lee RS, Geck P, Isselbacher KJ et al. The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis. Proc Natl Acad Sci USA 2004; 101: 2351-2356.
27. Mathai JP, Germain M, Shore GC. BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem 2005; 280: 23829-23836.
28. Zimmermann AK, Loucks FA, Schroeder EK, Bouchard RJ, Tyler KL, Linseman DA. Glutathione binding to the Bcl-2 homology-3 domain groove: A molecular basis for Bcl-2 antioxidant function at mitochondria. J Biol Chem 2007; 282: 29296-29304.
29. Steckley D, Karajgikar M, Dale LB, Fuerth B, Swan P, Drummond-Main C et al. Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis. J Neurosci 2007; 27: 12989-12999.
30. Kaufman RJ. Orchestrating the unfolded protein response in health and disease. J Clin Invest 2002; 110: 1389-1398.
31. Takahashi A, Aoshiba K, Nagai A. Apoptosis of wound fibroblasts induced by oxidative stress. Exp Lung Res 2002; 28: 275-284.
32. Miyoshi N, Oubrahim H, Chock PB, Stadtman ER. Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Proc Natl Acad Sci USA 2006; 103: 1727-1731.
33. Wang L, Ogburn CE, Ware CB, Ladiges WC, Youssoufian H, Martin GM et al. Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene. Genetics 2000; 154: 357-362.
34. Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 282: 1497-1501.
35. Gutierrez O, Pipaon C, Inohara N, Fontalba A, Ogura Y, Prosper F et al. Induction of Nod2 in myelomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation. J Biol Chem 2002; 277: 41701-41705.
36. Benito A, Silva M, Grillot D, Nunez G, Fernandez-Luna J. Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bcl-XL. Blood 1996; 87: 3837-3843.
37. Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 2000; 103: 843-852.
38. Morillas MJ, Guillamet E, Surralles J, Creus A, Marcos R. Spontaneous and induced genetic damage in T lymphocyte subsets evaluated by the Comet assay. Mutat Res 2002; 514: 39-48.