Synthesis and in vitro trichomonicidal, giardicidal and amebicidal activity of N-acetamide(sulfonamide)-2-methyl-4-nitro-1H-imidazoles

European Journal of Medicinal Chemistry

Volumn 44, Issue 7, 2009, Pages 2975-2984

  Hernández Núñez, Emanuel ^a   Tlahuext, Hugo ^b   Moo Puc, Rosa ^c   Torres Gómez, Héctor ^a   Reyes Martínez, Reyna ^b   Cedillo Rivera, Roberto ^c   Nava Zuazo, Carlos ^a   Navarrete Vazquez, Gabriel ^a  

^a UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MORELOS   (Mexico)

^b CENTRO DE INVESTIGACIONES QUÍMICAS   (Mexico)

^c UNIVERSIDAD AUTÓNOMA DE YUCATÁN   (Mexico)

Author keywords

4 Nitroimidazoles; Benznidazole; Entamoeba histolytica; Giardia intestinalis; Trichomonas vaginalis

Indexed keywords

1 [(4 CHLOROPHENYL)SULFONYL] 2 METHYL 4 NITRO 1H IMIDAZOLE; 1 [(4 FLUOROPHENYL)SULFONYL] 2 METHYL 4 NITRO 1H IMIDAZOLE; 1 [(4 METHOXYPHENYL)SULFONYL] 2 METHYL 4 NITRO 1H IMIDAZOLE; 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL) N (4 NITROPHENYL)ACETAMIDE; 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL) N [3 (TRIFLUOROMETHYL)PHENYL]ACETAMIDE; 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL) N PHENYLACETAMIDE; 2 CHLORO N (2,6 DICHLOROPHENYL)ACETAMIDE; 2 METHYL 1 [(4 METHYLPHENYL)SULFONYL] 4 NITRO 1H IMIDAZOLE; 2 METHYL 4 NITRO 1 (PHENYLSULFONYL) 1H IMIDAZOLE; 2 METHYL 4 NITRO 1 [(4 NITROPHENYL)SULFONYL] 1H IMIDAZOLE; ACETAMIDE DERIVATIVE; ANTIPARASITIC AGENT; BENZNIDAZOLE; METRONIDAZOLE; N (2,6 DICHLOROPHENYL) 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL)ACETAMIDE; N (4 CHLOROPHENYL) 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL)ACETAMIDE; N (4 CYANOPHENYL) 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL)ACETAMIDE; N (4 FLUOROPHENYL) 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL)ACETAMIDE; N [4 [(2 METHYL 4 NITRO 1H IMIDAZOL 1 YL)SULFONYL]PHENYL]ACETAMIDE; N BENZYL 2 (2 METHYL 4 NITRO 1H IMIDAZOL 1 YL)ACETAMIDE; NITROIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; GIARDIA LAMBLIA; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRICHOMONAS VAGINALIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENTAMOEBA HISTOLYTICA; GIARDIA LAMBLIA; IMIDAZOLES; NITROIMIDAZOLES; TRICHOMONAS VAGINALIS;

EID: 67349174267     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.01.005     Document Type: Article

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