-
1
-
-
0024424833
-
Effects of ovulen-50, diethylnitrosamine and phenobarbital on liver regeneration in female rats
-
Annapurna V., Mukundan M., Sesikeran B., and Bamji M. Effects of ovulen-50, diethylnitrosamine and phenobarbital on liver regeneration in female rats. J. Biosci. 14 (1989) 1-7
-
(1989)
J. Biosci.
, vol.14
, pp. 1-7
-
-
Annapurna, V.1
Mukundan, M.2
Sesikeran, B.3
Bamji, M.4
-
2
-
-
33745880401
-
Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins
-
Baskin-Bey E., Huang W., Ishimura N., Isomoto H., Bronk S., Braley K., Craig R., Moore D., and Gores G. Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Hepatology 44 (2006) 252-262
-
(2006)
Hepatology
, vol.44
, pp. 252-262
-
-
Baskin-Bey, E.1
Huang, W.2
Ishimura, N.3
Isomoto, H.4
Bronk, S.5
Braley, K.6
Craig, R.7
Moore, D.8
Gores, G.9
-
3
-
-
35648974265
-
Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse
-
Baskin-Bey E., Anan A., Isomoto H., Bronk S., and Gores G. Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse. World J. Gastroenterol. 13 (2007) 5635-5641
-
(2007)
World J. Gastroenterol.
, vol.13
, pp. 5635-5641
-
-
Baskin-Bey, E.1
Anan, A.2
Isomoto, H.3
Bronk, S.4
Gores, G.5
-
4
-
-
39149116716
-
Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis
-
Beilke L., Besselsen D., Cheng Q., Kulkarni S., Slitt A., and Cherrington N. Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis. Toxicol. Sci. 102 (2008) 196-204
-
(2008)
Toxicol. Sci.
, vol.102
, pp. 196-204
-
-
Beilke, L.1
Besselsen, D.2
Cheng, Q.3
Kulkarni, S.4
Slitt, A.5
Cherrington, N.6
-
5
-
-
0025847596
-
Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. I. Lack of dependence on glutathione
-
Davies M., Schamber G., and Schnell R. Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. I. Lack of dependence on glutathione. Toxicol. Appl. Pharmacol. 109 (1991) 17-28
-
(1991)
Toxicol. Appl. Pharmacol.
, vol.109
, pp. 17-28
-
-
Davies, M.1
Schamber, G.2
Schnell, R.3
-
6
-
-
0037314551
-
Comparison of immunohistochemistry for activated caspase-3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC-3 subcutaneous xenografts
-
Duan W., Garner D., Williams S., Funckes-Shippy C., Spath I., and Blomme E. Comparison of immunohistochemistry for activated caspase-3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC-3 subcutaneous xenografts. J. Pathol. 199 (2003) 221-228
-
(2003)
J. Pathol.
, vol.199
, pp. 221-228
-
-
Duan, W.1
Garner, D.2
Williams, S.3
Funckes-Shippy, C.4
Spath, I.5
Blomme, E.6
-
7
-
-
0031298259
-
Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death
-
Duriez P., and Shah G. Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death. Biochem. Cell Biol. 75 (1997) 337-349
-
(1997)
Biochem. Cell Biol.
, vol.75
, pp. 337-349
-
-
Duriez, P.1
Shah, G.2
-
8
-
-
0032919402
-
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
-
Faubion W., Guicciardi M., Miyoshi H., Bronk S., Roberts P., Svingen P., Kaufmann S., and Gores G. Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J. Clin. Invest. 103 (1999) 137-145
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 137-145
-
-
Faubion, W.1
Guicciardi, M.2
Miyoshi, H.3
Bronk, S.4
Roberts, P.5
Svingen, P.6
Kaufmann, S.7
Gores, G.8
-
9
-
-
0036787691
-
Prevention of bile acid-induced apoptosis by betaine in rat liver
-
Graf D., Kurz A., Reinehr R., Fischer R., Kircheis G., and Haussinger D. Prevention of bile acid-induced apoptosis by betaine in rat liver. Hepatology 36 (2002) 829-839
-
(2002)
Hepatology
, vol.36
, pp. 829-839
-
-
Graf, D.1
Kurz, A.2
Reinehr, R.3
Fischer, R.4
Kircheis, G.5
Haussinger, D.6
-
10
-
-
36749077202
-
2+-dependent apoptosis in vivo
-
2+-dependent apoptosis in vivo. Biochem. J. 408 (2007) 181-191
-
(2007)
Biochem. J.
, vol.408
, pp. 181-191
-
-
Graidist, P.1
Yazawa, M.2
Tonquanunt, M.3
Nakatomi, A.4
Lin, C.5
Chang, Y.6
Phongdara, A.7
Fujise, K.8
-
11
-
-
21044445452
-
Apoptosis: a mechanism of acute and chronic liver injury
-
Guicciardi M., and Gores G. Apoptosis: a mechanism of acute and chronic liver injury. Gut 54 (2006) 1024-1033
-
(2006)
Gut
, vol.54
, pp. 1024-1033
-
-
Guicciardi, M.1
Gores, G.2
-
12
-
-
0031695083
-
Quantitative differentiation of both free 3′ -OH and 5′ -OH DNA ends between heat-induced apoptosis and necrosis
-
Hayashi R., Ito Y., Matsumoto K., Fujino Y., and Otsuki Y. Quantitative differentiation of both free 3′ -OH and 5′ -OH DNA ends between heat-induced apoptosis and necrosis. J. Histochem. Cytochem. 46 (1998) 1051-1059
-
(1998)
J. Histochem. Cytochem.
, vol.46
, pp. 1051-1059
-
-
Hayashi, R.1
Ito, Y.2
Matsumoto, K.3
Fujino, Y.4
Otsuki, Y.5
-
13
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M. The biochemistry of apoptosis. Nature 407 (2000) 770-775
-
(2000)
Nature
, vol.407
, pp. 770-775
-
-
Hengartner, M.1
-
14
-
-
0031968936
-
Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10 gene
-
Honkakoski P., Moore R., Washburn K., and Negishi M. Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10 gene. Mol. Pharmacol. 53 (1998) 597-601
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 597-601
-
-
Honkakoski, P.1
Moore, R.2
Washburn, K.3
Negishi, M.4
-
15
-
-
22344451423
-
Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor
-
Huang W., Zhang J., Washington M., Liu J., Parant J., Lozano G., and Moore D. Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor. Mol. Endocrinol. 19 (2005) 1646-1653
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 1646-1653
-
-
Huang, W.1
Zhang, J.2
Washington, M.3
Liu, J.4
Parant, J.5
Lozano, G.6
Moore, D.7
-
16
-
-
0037154380
-
Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-b1 and tumor necrosis factor-a expression
-
Kang K., Choi S., Ha J., Kim C., and Kim S. Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-b1 and tumor necrosis factor-a expression. Chem. Biol. Interact. 139 (2002) 61-77
-
(2002)
Chem. Biol. Interact.
, vol.139
, pp. 61-77
-
-
Kang, K.1
Choi, S.2
Ha, J.3
Kim, C.4
Kim, S.5
-
17
-
-
0038719699
-
Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity
-
Kitada H., Miyata M., Nakamura T., Tozawa A., Honma W., Shimada M., Nagata K., Sinal C., Guo G., Gonzalez F., and Yamazoe Y. Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity. J. Biol. Chem. 278 (2003) 17838-17844
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17838-17844
-
-
Kitada, H.1
Miyata, M.2
Nakamura, T.3
Tozawa, A.4
Honma, W.5
Shimada, M.6
Nagata, K.7
Sinal, C.8
Guo, G.9
Gonzalez, F.10
Yamazoe, Y.11
-
18
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: a switch in detection between apoptosis and necrosis
-
Leist M., Single B., Castoldi A., Kuhnle S., and Nicotera P. Intracellular adenosine triphosphate (ATP) concentration: a switch in detection between apoptosis and necrosis. J. Exp. Med. 185 (1997) 1481-1486
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.3
Kuhnle, S.4
Nicotera, P.5
-
19
-
-
47949097721
-
The Nrf2 activator oltipraz also activates the constitutive androstane receptor
-
[Epub ahead of print]
-
Merrell M., Jackson J., Augustine L., Fisher C., Slitt A., Maher J., Huang W., Moore D., Zhang Y., Klaassen C., and Cherrington N. The Nrf2 activator oltipraz also activates the constitutive androstane receptor. Drug Metab. Dispos. (2008) [Epub ahead of print]
-
(2008)
Drug Metab. Dispos.
-
-
Merrell, M.1
Jackson, J.2
Augustine, L.3
Fisher, C.4
Slitt, A.5
Maher, J.6
Huang, W.7
Moore, D.8
Zhang, Y.9
Klaassen, C.10
Cherrington, N.11
-
21
-
-
0032525819
-
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
-
Rodrigues C., Fan G., Ma X., Kren B., and Steer C. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J. Clin. Invest. 101 (1998) 2790-2799
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2790-2799
-
-
Rodrigues, C.1
Fan, G.2
Ma, X.3
Kren, B.4
Steer, C.5
-
22
-
-
9144231188
-
A novel constitutive androstane receptor-mediated and Cyp3A-independent pathway of bile acid detoxification
-
Saini S., Sonoda J., Xu L., Toma D., Uppal H., Mu Y., Ren S., Moore D., and Xie W. A novel constitutive androstane receptor-mediated and Cyp3A-independent pathway of bile acid detoxification. Mol. Pharmacol. 65 (2004) 292-300
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 292-300
-
-
Saini, S.1
Sonoda, J.2
Xu, L.3
Toma, D.4
Uppal, H.5
Mu, Y.6
Ren, S.7
Moore, D.8
Xie, W.9
-
23
-
-
0029891535
-
Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions
-
Shimizu S., Eguchi Y., Kamiike W., Waguri S., Uchiyama Y., Matsuda H., and Tsujimoto Y. Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. Oncogene 12 (1996) 2045-2050
-
(1996)
Oncogene
, vol.12
, pp. 2045-2050
-
-
Shimizu, S.1
Eguchi, Y.2
Kamiike, W.3
Waguri, S.4
Uchiyama, Y.5
Matsuda, H.6
Tsujimoto, Y.7
-
24
-
-
0033936183
-
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas
-
Sodeman T., Bronk S., Roberts P., Miyoshi H., and Gores G. Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am. J. Physiol. Gastrointest. Liver Physiol. 278 (2000) G992-G999
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.278
-
-
Sodeman, T.1
Bronk, S.2
Roberts, P.3
Miyoshi, H.4
Gores, G.5
-
25
-
-
33749433408
-
Modulation of hepatocyte apoptosis: cross-talk between bile acids and nuclear steroid receptors
-
Sola S., Amaral J., Aranha M., Steer C., and Rodrigues C. Modulation of hepatocyte apoptosis: cross-talk between bile acids and nuclear steroid receptors. Curr. Med. Chem. 13 (2006) 3039-3051
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 3039-3051
-
-
Sola, S.1
Amaral, J.2
Aranha, M.3
Steer, C.4
Rodrigues, C.5
-
26
-
-
0034782509
-
Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor
-
Staudinger J., Liu Y., Madan A., Habeebu S., and Klaassen C. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor. Drug Metab. Dispos. 29 (2001) 1467-1472
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1467-1472
-
-
Staudinger, J.1
Liu, Y.2
Madan, A.3
Habeebu, S.4
Klaassen, C.5
-
27
-
-
13844315320
-
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury
-
Stedman C., Liddle C., Coulter S., Sonoda J., Alvarez J., Moore D., Evans R., and Downes M. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2063-2068
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2063-2068
-
-
Stedman, C.1
Liddle, C.2
Coulter, S.3
Sonoda, J.4
Alvarez, J.5
Moore, D.6
Evans, R.7
Downes, M.8
-
28
-
-
34249747403
-
Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis
-
Teng S., and Piquette-Miller M. Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis. Br. J. Pharmacol. 151 (2007) 367-376
-
(2007)
Br. J. Pharmacol.
, vol.151
, pp. 367-376
-
-
Teng, S.1
Piquette-Miller, M.2
-
30
-
-
0036142429
-
Diverse roles of the nuclear receptor CAR in regulating hepatic genes in response to phenobarbital
-
Ueda A., Hamadeh H., Webb H., Yamamoto Y., Sueyoshi T., Afshari C., Lehmann J., and Negishi M. Diverse roles of the nuclear receptor CAR in regulating hepatic genes in response to phenobarbital. Mol. Pharmacol. 61 (2002) 1-6
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1-6
-
-
Ueda, A.1
Hamadeh, H.2
Webb, H.3
Yamamoto, Y.4
Sueyoshi, T.5
Afshari, C.6
Lehmann, J.7
Negishi, M.8
-
31
-
-
0037020234
-
Physical and functional interactions between myeloid cell leukemia 1 protein (MCL1) and fortilin
-
Zhang D., Franklin L., Weidner D., Mnjoyan Z., and Fujise K. Physical and functional interactions between myeloid cell leukemia 1 protein (MCL1) and fortilin. J. Biol. Chem. 277 (2002) 37430-37438
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37430-37438
-
-
Zhang, D.1
Franklin, L.2
Weidner, D.3
Mnjoyan, Z.4
Fujise, K.5
-
32
-
-
10344224570
-
The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity
-
Zhang J., Huang W., Qatanani M., Evans R., and Moore D. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. J. Biol. Chem. 279 (2004) 49517-49522
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49517-49522
-
-
Zhang, J.1
Huang, W.2
Qatanani, M.3
Evans, R.4
Moore, D.5
-
33
-
-
23444453717
-
Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes
-
Zucchini N., de Sousa G., Bailly-Maitre B., Gugenheim J., Bars R., Lemaire G., and Rahmani R. Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes. Biochim. Biophys. Acta 1745 (2005) 48-58
-
(2005)
Biochim. Biophys. Acta
, vol.1745
, pp. 48-58
-
-
Zucchini, N.1
de Sousa, G.2
Bailly-Maitre, B.3
Gugenheim, J.4
Bars, R.5
Lemaire, G.6
Rahmani, R.7
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