Protein load impairs factor H binding promoting complement-dependent dysfunction of proximal tubular cells

Kidney International

Volumn 75, Issue 10, 2009, Pages 1050-1059

  Buelli, Simona ^a   Abbate, Mauro ^a   Morigi, Marina ^a   Moioli, Daniela ^a   Zanchi, Cristina ^a   Noris, Marina ^a   Zoja, Carla ^a   Pusey, Charles D ^b   Zipfel, Peter F ^c,d   Remuzzi, Giuseppe ^a,e  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c HANS KNÖLL INSTITUTE   (Germany)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^e OSPEDALI RIUNITI   (Italy)

Author keywords

Albumin; Chemokines; Complement; Cytokines; Factor H; Transferrin

Indexed keywords

ALBUMIN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT FACTOR H; COMPLEMENT MEMBRANE ATTACK COMPLEX; EGTAZIC ACID; FRACTALKINE; MAGNESIUM CHLORIDE; MESSENGER RNA; PROTEOHEPARAN SULFATE; TRANSFERRIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT DEPOSITION; COMPLEMENT LECTIN PATHWAY; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNE DYSREGULATION; INFLAMMATION; KIDNEY TUBULE CELL; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN SYNTHESIS; SERUM; TUBULAR DYSFUNCTION; UPREGULATION;

EID: 67349154086     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2009.8     Document Type: Article

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