Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H

Journal of Immunology

Volumn 169, Issue 12, 2002, Pages 6935-6944

  Hellwage, Jens ^a,b   Jokiranta, T Sakari ^a   Friese, Manuel A ^c   Wolk, Tobias U ^c   Kampen, Eva ^c   Zipfel, Peter F ^b,c   Meri, Seppo ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HANS KNÖLL INSTITUTE   (Germany)

^c BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3D; COMPLEMENT FACTOR H; FH RELATED PROTEIN; POLYANION; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; APOLIPOPROTEIN; CFHL4 PROTEIN, HUMAN; COMPLEMENT FACTOR H, HUMAN; FACTOR H RELATED PROTEIN 1; FACTOR H RELATED PROTEIN 3; FACTOR H-RELATED PROTEIN 1; FACTOR H-RELATED PROTEIN 3; HEPARIN; PLASMA PROTEIN; POLYANIONS; POLYMER;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; COMPLEMENT SYSTEM; CONSENSUS SEQUENCE; GENE MUTATION; HEMOLYTIC UREMIC SYNDROME; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SHORT CONSENSUS REPEAT DOMAIN; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE; WESTERN BLOTTING; AMINO ACID SEQUENCE; CELL MEMBRANE; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; APOLIPOPROTEINS; BINDING SITES; BLOOD PROTEINS; CELL MEMBRANE; COMPLEMENT C3B; COMPLEMENT C3D; COMPLEMENT FACTOR H; CONSERVED SEQUENCE; HEPARIN; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POLYMERS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; SEQUENCE ANALYSIS, PROTEIN;

EID: 0037114145     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.12.6935     Document Type: Article

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