Old mice retain bone marrow B1 progenitors, but lose B2 precursors, and exhibit altered immature B cell phenotype and light chain usage

Mechanisms of Ageing and Development

Volumn 130, Issue 6, 2009, Pages 401-408

  Alter Wolf, Sarah ^a   Blomberg, Bonnie B ^a   Riley, Richard L ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

B cell precursors; B1 B cells; Light chain; Lymphopoiesis; Senescence; Surrogate light chain

Indexed keywords

CD19 ANTIGEN; IMMUNOGLOBULIN M; LEUKOSIALIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; BONE MARROW; CONTROLLED STUDY; LIGHT CHAIN; LYMPHOPOIESIS; MOUSE; NONHUMAN; PHENOTYPE; PRE B LYMPHOCYTE; PRIORITY JOURNAL;

AGE FACTORS; AGING; ANIMALS; ANTIGENS, CD19; ANTIGENS, CD43; ANTIGENS, CD45; BONE MARROW CELLS; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN LIGHT CHAINS, SURROGATE; IMMUNOPHENOTYPING; LYMPHOPOIESIS; MALE; MICE; MICE, INBRED BALB C; PHENOTYPE; PRECURSOR CELLS, B-LYMPHOID;

MUS;

EID: 67349143418     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.04.001     Document Type: Article

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