메뉴 건너뛰기




Volumn 14, Issue 3, 2003, Pages 546-553

Monoclonal antibody radiopharmaceuticals: Cationization, pegylation, radiometal chelation, pharmacokinetics, and tumor imaging

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROPHORESIS; MAMMALS; PHARMACOKINETICS; POLYETHYLENE GLYCOLS; RADIOGRAPHY; TUMORS;

EID: 0037908924     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0256648     Document Type: Article
Times cited : (80)

References (17)
  • 1
    • 0035558017 scopus 로고    scopus 로고
    • Radiolabeled immunoglobulin therapy: Old barriers and new opportunities
    • Vriesendorp, H. M., and Quadri, S. M. (2001) Radiolabeled immunoglobulin therapy: Old barriers and new opportunities. Expert Rev. Anticancer Ther. 1, 461-478.
    • (2001) Expert Rev. Anticancer Ther. , vol.1 , pp. 461-478
    • Vriesendorp, H.M.1    Quadri, S.M.2
  • 2
    • 0001120209 scopus 로고
    • Blood-brain barrier transport of cationized immunoglobulin G: Enhanced delivery compared to native protein
    • Triguero, D., Buciak, J. B., Yang, J., and Pardridge, W. M. (1989) Blood-brain barrier transport of cationized immunoglobulin G: Enhanced delivery compared to native protein. Proc. Natl. Acad. Sci. 86, 4761-4765.
    • (1989) Proc. Natl. Acad. Sci. , vol.86 , pp. 4761-4765
    • Triguero, D.1    Buciak, J.B.2    Yang, J.3    Pardridge, W.M.4
  • 3
    • 0005849853 scopus 로고
    • Degradation of cationized low-density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts
    • Basu, S. K., Goldstein, J. L., Anderson, R. G. W., and Brown, M. S., (1976) Degradation of cationized low-density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 73, 1378-3182.
    • (1976) Proc. Natl. Acad. Sci. U.S.A. , vol.73 , pp. 1378-3182
    • Basu, S.K.1    Goldstein, J.L.2    Anderson, R.G.W.3    Brown, M.S.4
  • 4
    • 0011766331 scopus 로고
    • Conjugation of polyL-lysine to albumin and horseradish peroxidase: A novel method of enhancing the cellular uptake of proteins
    • Shen, W.-C. and Ryser, H. J.-P. (1978) Conjugation of polyL-lysine to albumin and horseradish peroxidase: A novel method of enhancing the cellular uptake of proteins. Proc. Natl. Acad. Sci. U.S.A. 75, 1872-1876.
    • (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 1872-1876
    • Shen, W.-C.1    Ryser, H.J.-P.2
  • 5
    • 0024390069 scopus 로고
    • Ultracytochemical characterization of anionic sites in the wall of brain capillaries
    • Vorbrodt, A. W. (1989) Ultracytochemical characterization of anionic sites in the wall of brain capillaries. J. Neurocytol. 18, 359-368.
    • (1989) J. Neurocytol. , vol.18 , pp. 359-368
    • Vorbrodt, A.W.1
  • 6
    • 0023938252 scopus 로고    scopus 로고
    • Microinjection of fos-specific antiboides blocks DNA synthesis in fibroblast cells
    • Riabowol, K. T., Vosatka, R. J., Ziff, E. B., Lamb, N. J., and Feramisco, J. R. (1998) Microinjection of fos-specific antiboides blocks DNA synthesis in fibroblast cells. Mol. Cell. Biol. 8, 1670-1676.
    • (1998) Mol. Cell. Biol. , vol.8 , pp. 1670-1676
    • Riabowol, K.T.1    Vosatka, R.J.2    Ziff, E.B.3    Lamb, N.J.4    Feramisco, J.R.5
  • 7
    • 0029092948 scopus 로고
    • 125I-labeled cationized monoclonal antibody against β-amyloid in mouse and dog
    • 125I-labeled cationized monoclonal antibody against β-amyloid in mouse and dog. Drug Deliv. 2, 128-135.
    • (1995) Drug Deliv. , vol.2 , pp. 128-135
    • Bickel, U.1    Lee, V.M.Y.2    Pardridge, W.M.3
  • 8
    • 0029115713 scopus 로고
    • Enhanced cellular uptake and in vivo biodistribution of a monoclonal antibody following cationization
    • Pardridge, W. M., Kang, Y.-S., Yang, J., and Buciak, J. L. (1995) Enhanced cellular uptake and in vivo biodistribution of a monoclonal antibody following cationization. J. Pharm. Sci. 84, 943-948.
    • (1995) J. Pharm. Sci. , vol.84 , pp. 943-948
    • Pardridge, W.M.1    Kang, Y.-S.2    Yang, J.3    Buciak, J.L.4
  • 9
    • 0031869867 scopus 로고    scopus 로고
    • Enhanced endocytosis in cultured human breast carcinoma cells and in vivo biodistribution in rats of a humanized monoclonal antibody following cationization of the protein
    • Pardridge, W. M., Buciak, J., Yang, J., and Wu, D. (1998) Enhanced endocytosis in cultured human breast carcinoma cells and in vivo biodistribution in rats of a humanized monoclonal antibody following cationization of the protein. J. Pharmacol. Exp. Ther. 286, 548-554.
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 548-554
    • Pardridge, W.M.1    Buciak, J.2    Yang, J.3    Wu, D.4
  • 10
    • 0028091458 scopus 로고
    • Cationization of a monoclonal antibody to the human immunodeficiency virus rev protein enhances cellular uptake but does not impair antigen binding of the antibody
    • Pardridge, W. M., Bickel, U., Buciak, J., Yang, J., Diagne, A., and Aepinus, C. (1994) Cationization of a monoclonal antibody to the human immunodeficiency virus rev protein enhances cellular uptake but does not impair antigen binding of the antibody. Immunol. Lett. 42, 191-195.
    • (1994) Immunol. Lett. , vol.42 , pp. 191-195
    • Pardridge, W.M.1    Bickel, U.2    Buciak, J.3    Yang, J.4    Diagne, A.5    Aepinus, C.6
  • 11
    • 0032904706 scopus 로고    scopus 로고
    • Pharmacokinetics and organ distribution of cationized colchicine-specific IgG and Fab fragments in rat
    • Hong, G., Bazin-Redureau, M. I., and Scherrmann, J. M. G. (1999) Pharmacokinetics and organ distribution of cationized colchicine-specific IgG and Fab fragments in rat. J. Pharm. Sci. 88, 147-153.
    • (1999) J. Pharm. Sci. , vol.88 , pp. 147-153
    • Hong, G.1    Bazin-Redureau, M.I.2    Scherrmann, J.M.G.3
  • 12
    • 0033136645 scopus 로고    scopus 로고
    • 111In chelation, conjugation to a blood-brain barrier delivery vector via a biotin-polyethylene linker, pharmacokinetics, and in vivo imaging of experimental brain tumors
    • 111In chelation, conjugation to a blood-brain barrier delivery vector via a biotin-polyethylene linker, pharmacokinetics, and in vivo imaging of experimental brain tumors. Bioconjugate Chem. 10, 502-511.
    • (1999) Bioconjugate Chem. , vol.10 , pp. 502-511
    • Kurihara, A.1    Deguchi, Y.2    Pardridge, W.M.3
  • 14
    • 0033572574 scopus 로고    scopus 로고
    • Imaging brain tumors by targeting peptide radiopharmaceuticals through the blood-brain barrier
    • Kurihara, A. and Pardridge, W. M. (1999) Imaging brain tumors by targeting peptide radiopharmaceuticals through the blood-brain barrier. Cancer Res. 54, 6159-6163.
    • (1999) Cancer Res. , vol.54 , pp. 6159-6163
    • Kurihara, A.1    Pardridge, W.M.2
  • 15
    • 0029000058 scopus 로고
    • Targeting of an anti-CR3 (CDllb/CD18) monoclonal antibody to spleen, but not brain, in vivo in mice
    • Skarlatos, S. and Pardridge, W. M. (1995) Targeting of an anti-CR3 (CDllb/CD18) monoclonal antibody to spleen, but not brain, in vivo in mice. J. Drug Targeting 3, 9-14.
    • (1995) J. Drug Targeting , vol.3 , pp. 9-14
    • Skarlatos, S.1    Pardridge, W.M.2
  • 16
    • 0029873942 scopus 로고    scopus 로고
    • Cationized hyperimmune immunoglobulins: Pharmacokinetics, toxicity evaluation, and treatment of HIV-infected scid-hu mice
    • Pardridge, W. M., Kang, Y. S., Diagne, A., and Zack, J. A. (1996) Cationized hyperimmune immunoglobulins: Pharmacokinetics, toxicity evaluation, and treatment of HIV-infected scid-hu mice. J. Pharmacol. Exp. Ther. 276, 246-252.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 246-252
    • Pardridge, W.M.1    Kang, Y.S.2    Diagne, A.3    Zack, J.A.4
  • 17
    • 0026124772 scopus 로고
    • The therapeutic value of poly(ethylene glycol)-modified proteins
    • Nucci, M. L., Shorr, R., and Abuchowski, A. (1991) The therapeutic value of poly(ethylene glycol)-modified proteins. Adv. Drug Deliv. Rev. 6, 133-151.
    • (1991) Adv. Drug Deliv. Rev. , vol.6 , pp. 133-151
    • Nucci, M.L.1    Shorr, R.2    Abuchowski, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.