The adenoviral vector-mediated increase in apurinic/apyrimidinic endonuclease inhibits the induction of neuronal cell death after transient ischemic stroke in mice

Brain Research

Volumn 1274, Issue , 2009, Pages 1-10

  Kim, Hyun Woo ^a   Cho, Kyoung Joo ^a   Park, Soo Chul ^a   Kim, Hyun Jeong ^a   Kim, Gyung W ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Adenoviral vector; Cerebral ischemia; DNA fragmentation; DNA repair

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOVIRUS VECTOR; APURINIC APYRIMIDINIC ENDONUCLEASE REDOX EFFECTOR FACTOR 1 FUSION PROTEIN; CELL NUCLEUS DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; REDOX EFFECTOR FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; CORPUS STRIATUM; DNA DAMAGE; DNA FRAGMENTATION; EXPRESSION VECTOR; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC ANALYSIS; IN VIVO GENE TRANSFER; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; REPERFUSION INJURY; TRANSIENT ISCHEMIC ATTACK; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CEREBROVASCULAR CIRCULATION; DNA FRAGMENTATION; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; FLUORESCENT ANTIBODY TECHNIQUE; FREE RADICALS; GENE THERAPY; GENETIC VECTORS; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; LASER-DOPPLER FLOWMETRY; MALE; MICE; MICE, INBRED C57BL; NEURONS; OXIDATIVE STRESS; REPERFUSION INJURY;

MUS;

EID: 67349136008     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.04.006     Document Type: Article

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