Design of novel indolicidin-derived antimicrobial peptides with enhanced cell specificity and potent anti-inflammatory activity

Peptides

Volumn 30, Issue 5, 2009, Pages 832-838

  Nan, Yong Hai ^a   Bang, Jeong Kyu ^b   Shin, Song Yub ^a,c  

^a Chosun University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c Chosun University College of Medicine   (South Korea)

Author keywords

Anti inflammatory activity; Antimicrobial peptide; Cell specificity; DNA binding activity; Indolicidin analogs; LPS binding activity

Indexed keywords

CALCEIN; INDOLICIDIN; INDUCIBLE NITRIC OXIDE SYNTHASE; ION CHANNEL; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; POLYPEPTIDE ANTIBIOTIC AGENT;

ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; CELL SPECIFICITY; DRUG POTENCY; MACROPHAGE; MICROORGANISM; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BASE SEQUENCE; CELL LINE; DNA PRIMERS; FLUORESCEINS; HEMOLYSIS; HUMANS; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PEPTIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); BOVINAE; STAPHYLOCOCCUS AUREUS;

EID: 67349115698     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.01.015     Document Type: Article

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