SMAP-29 has two LPS-binding sites and a central hinge

European Journal of Biochemistry

Volumn 269, Issue 4, 2002, Pages 1181-1189

  Tack, Brian F ^a   Sawai, Monali V ^a   Kearney, William R ^b   Robertson, Andrew D ^a   Sherman, Mark A ^c   Wang, Wei ^d   Hong, Teresa ^d   Boo, Lee Ming ^d   Wu, Huiyuan ^d   Waring, Alan J ^d   Lehrer, Robert I ^d,e  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Binding; Cathelicidin; Cooperativity; LPS; SMAP 29

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; PEPTIDE; PEPTIDE CAP 18; PEPTIDE SMAP 29; TRIFLUOROETHANOL; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; DRUG POTENCY; HYDROPHOBICITY; MOLECULAR MODEL; MOLECULE; NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SHEEP; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; BINDING SITES; BLOOD PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SHEEP; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

ESCHERICHIA COLI; LIMULUS; ORYCTOLAGUS CUNICULUS; OVIS ARIES;

EID: 0036178436     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0014-2956.2002.02751.x     Document Type: Article

References (36)

1. SMAP-29: A potent antibacterial and antifungal peptide from sheep leukocytes
2. Molecular analysis of the sheep cathelin family reveals a novel antimicrobial peptide
3. Bactericidal activity of mammalian cathelicidin-derived peptides
4. Evaluation of antimicrobial and lipopolysaccharide-neutralizing effects of a synthetic CAP18 fragment against Pseudomonas aeruginosa in a mouse model
5. Complementary DNA sequence of rabbit CAP18 - A unique lipopolysaccharide binding protein
6. Antimicrobial action of rabbit leukocyte CAP18 (106-137)
7. Identification and characterization of a primary antibacterial domain in CAP18, a lipopolysaccharide binding protein from rabbit leukocytes
8. Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide
9. Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37
10. FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis
11. Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils
12. Potassium release, a useful tool for studying antimicrobial peptides
13. The combinations of hemoglobin with oxygen and with carbon monoxide. I
14. Ultrasensitive assays for endogenous antimicrobial polypeptides
15. Protein secondary structure and circular dichroism: A practical guide
16. Determination of the helix and beta form of proteins in aqueous solution by circular dichroism
17. Torsion angle dynamics for NMR structure calculation with the new program DYANA
18. A new approach to analysis and display of local lipophilicity/hydrophilicity mapped on molecular surfaces
19. AQUA and PROCHECK-NMR: Program for checking the quality of protein structures solved by NMR
20. Trifluoroethanol and colleagues: Cosolvents come of age. Recent studies with peptides and proteins
21. Attenuated total reflection infrared spectroscopy of proteins and lipids in biological membranes
22. Effect of pH on solubility and ionic state of lipopolysaccharide obtained from the deep rough mutant of Escherichia coli
23. Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide
24. Interaction of divalent cations and polymyxin B with lipopolysaccharide
25. Lipopolysaccharide bilayer structure: Effect of chemotype, core mutations, divalent cations, and temperature
26. The solution structure of the active domain of CAP18 - A lipopolysaccharide binding protein from rabbit leukocytes
27. Molecular mechanisms of interaction of rabbit CAP18 with outer membranes of gram-negative bacteria
28. Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa
29. Involvement of outer membrane of Pseudomonas cepacia in aminoglycoside and polymyxin resistance
30. Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5 Å resolution
31. The BPI/LBP family of proteins: A structural analysis of conserved regions
32. Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution
33. High-affinity LPS binding domain(s) in recombinant factor C of a horseshoe crab neutralizes LPS-induced lethality
34. Definition of endotoxin binding sites in horseshoe crab factor C recombinant sushi proteins and neutralization of endotoxin by sushi peptides
35. The chemical shift index: A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy