-
1
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
DOI 10.1126/science.1141634
-
TM Frayling NJ Timpson MN Weedon 2007 A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity Science 316 889 894 (Pubitemid 46764279)
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.-R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.F.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.A.36
Doney, A.S.F.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
2
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
DOI 10.1371/journal.pgen.0030115
-
A Scuteri S Sanna WM Chen 2007 Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits PLoS Genet 3 e115 (Pubitemid 47203970)
-
(2007)
PLoS Genetics
, vol.3
, Issue.7
, pp. 1200-1210
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.-M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orru, M.9
Usala, G.10
Dei, M.11
Lai, S.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Ehret, G.B.16
Fink, A.A.17
Weder, A.B.18
Cooper, R.S.19
Galan, P.20
Chakravarti, A.21
Schlessinger, D.22
Cao, A.23
Lakatta, E.24
Abecasis, G.R.25
more..
-
3
-
-
41749090524
-
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
-
A Hinney TT Nguyen A Scherag 2007 Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants PLoS ONE 2 e1361
-
(2007)
PLoS ONE
, vol.2
, pp. 1361
-
-
Hinney, A.1
Nguyen, T.T.2
Scherag, A.3
-
4
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
RJ Loos CM Lindgren S Li 2008 Common variants near MC4R are associated with fat mass, weight and risk of obesity Nat Genet 40 768 775
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
-
5
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
DOI 10.1038/ng2048, PII NG2048
-
C Dina D Meyre S Gallina 2007 Variation in FTO contributes to childhood obesity and severe adult obesity Nat Genet 39 724 726 (Pubitemid 46848595)
-
(2007)
Nature Genetics
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.S.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
Bougneres, P.21
Kovacs, P.22
Marre, M.23
Balkau, B.24
Cauchi, S.25
Chevre, J.-C.26
Froguel, P.27
more..
-
6
-
-
42049117134
-
The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks
-
Lopez-Bermejo A, Petry CJ, Diaz M et al (2008) The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab 93:1501-1505
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 1501-1505
-
-
Lopez-Bermejo, A.1
Petry, C.J.2
Diaz, M.3
-
7
-
-
38449098674
-
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
-
CH Andreasen KL Stender-Petersen MS Mogensen 2008 Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation Diabetes 57 95 101
-
(2008)
Diabetes
, vol.57
, pp. 95-101
-
-
Andreasen, C.H.1
Stender-Petersen, K.L.2
Mogensen, M.S.3
-
8
-
-
39949083566
-
Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes
-
JA Jacobsson P Danielsson V Svensson 2008 Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes Biochem Biophys Res Commun 368 476 482
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 476-482
-
-
Jacobsson, J.A.1
Danielsson, P.2
Svensson, V.3
-
9
-
-
51649099799
-
Physical activity and the association of common FTO gene variants with body mass index and obesity
-
E Rampersaud BD Mitchell TI Pollin 2008 Physical activity and the association of common FTO gene variants with body mass index and obesity Arch Intern Med 168 1791 1797
-
(2008)
Arch Intern Med
, vol.168
, pp. 1791-1797
-
-
Rampersaud, E.1
Mitchell, B.D.2
Pollin, T.I.3
-
10
-
-
40949123295
-
Insights from the genetics of severe childhood obesity
-
S Farooqi 2007 Insights from the genetics of severe childhood obesity Horm Res 68 Suppl 5 5 7
-
(2007)
Horm Res 68 Suppl
, vol.5
, pp. 5-7
-
-
Farooqi, S.1
-
11
-
-
33749017409
-
The human obesity gene map: The 2005 update
-
T Rankinen A Zuberi YC Chagnon 2006 The human obesity gene map: the 2005 update Obesity (Silver Spring) 14 529 644 (Pubitemid 46219737)
-
(2006)
Obesity
, vol.14
, Issue.4
, pp. 529-644
-
-
Rankinen, T.1
Zuberi, A.2
Chagnon, Y.C.3
Weisnagel, S.J.4
Argyropoulos, G.5
Walts, B.6
Perusse, L.7
Bouchard, C.8
-
12
-
-
39749116842
-
FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs
-
RA Price WD Li H Zhao 2008 FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs BMC Med Genet 9 4
-
(2008)
BMC Med Genet
, vol.9
, pp. 4
-
-
Price, R.A.1
Li, W.D.2
Zhao, H.3
-
13
-
-
40749094439
-
Variants in the FTO gene are associated with common obesity in the Belgian population
-
A Peeters S Beckers A Verrijken 2008 Variants in the FTO gene are associated with common obesity in the Belgian population Mol Genet Metab 93 481 484
-
(2008)
Mol Genet Metab
, vol.93
, pp. 481-484
-
-
Peeters, A.1
Beckers, S.2
Verrijken, A.3
-
15
-
-
51849111090
-
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
-
SI Kring C Holst E Zimmermann 2008 FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness PLoS ONE 3 e2958
-
(2008)
PLoS ONE
, vol.3
, pp. 2958
-
-
Kring, S.I.1
Holst, C.2
Zimmermann, E.3
-
16
-
-
44749083224
-
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI
-
RM Freathy NJ Timpson DA Lawlor 2008 Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI Diabetes 57 1419 1426
-
(2008)
Diabetes
, vol.57
, pp. 1419-1426
-
-
Freathy, R.M.1
Timpson, N.J.2
Lawlor, D.A.3
-
17
-
-
43049149732
-
Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
-
JK Hertel S Johansson H Raeder 2008 Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study) Diabetologia 51 971 977
-
(2008)
Diabetologia
, vol.51
, pp. 971-977
-
-
Hertel, J.K.1
Johansson, S.2
Raeder, H.3
-
18
-
-
50449104632
-
Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
-
MC Ng KS Park B Oh 2008 Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians Diabetes 57 2226 2233
-
(2008)
Diabetes
, vol.57
, pp. 2226-2233
-
-
Ng, M.C.1
Park, K.S.2
Oh, B.3
-
19
-
-
47749128415
-
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
-
DK Sanghera L Ortega S Han 2008 Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk BMC Med Genet 9 59
-
(2008)
BMC Med Genet
, vol.9
, pp. 59
-
-
Sanghera, D.K.1
Ortega, L.2
Han, S.3
-
20
-
-
54949113309
-
The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change, and diabetes risk in women
-
Qi L, Kraft P, Hunter DJ et al (2008) The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change, and diabetes risk in women. Hum Mol Genet 17:3502-3508
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3502-3508
-
-
Qi, L.1
Kraft, P.2
Hunter, D.J.3
-
21
-
-
47549107452
-
Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity
-
T Berentzen SI Kring C Holst 2008 Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity J Clin Endocrinol Metab 93 2904 2908
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 2904-2908
-
-
Berentzen, T.1
Kring, S.I.2
Holst, C.3
-
22
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
D Huszar CA Lynch V Fairchild-Huntress 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice Cell 88 131 141 (Pubitemid 27180337)
-
(1997)
Cell
, vol.88
, Issue.1
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Frank, L.14
-
23
-
-
6344260502
-
Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index
-
DOI 10.1136/jmg.2004.018614
-
A Dempfle A Hinney M Heinzel-Gutenbrunner 2004 Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index J Med Genet 41 795 800 (Pubitemid 39389299)
-
(2004)
Journal of Medical Genetics
, vol.41
, Issue.10
, pp. 795-800
-
-
Dempfle, A.1
Hinney, A.2
Heinzel-Gutenbrunner, M.3
Raab, M.4
Geller, F.5
Gudermann, T.6
Schafer, H.7
Hebebrand, J.8
-
24
-
-
52749092130
-
Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees
-
F Stutzmann K Tan V Vatin 2008 Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees Diabetes 57 2511 2518
-
(2008)
Diabetes
, vol.57
, pp. 2511-2518
-
-
Stutzmann, F.1
Tan, K.2
Vatin, V.3
-
25
-
-
0024594999
-
Androgen regulation of proopiomelanocortin gene expression and peptide content in the basal hypothalamus
-
M Blum JL Roberts SL Wardlaw 1989 Androgen regulation of proopiomelanocortin gene expression and peptide content in the basal hypothalamus Endocrinology 124 2283 2288 (Pubitemid 19132028)
-
(1989)
Endocrinology
, vol.124
, Issue.5
, pp. 2283-2288
-
-
Blum, M.1
Roberts, J.L.2
Wardlaw, S.L.3
-
26
-
-
9844229896
-
Proposed criteria for the diagnosis of diabetes: Evidence from a French epidemiological study (D.E.S.I.R.)
-
B Balkau E Eschwege J Tichet 1997 Proposed criteria for the diagnosis of diabetes: evidence from a French epidemiological study (D.E.S.I.R.) Diabetes Metab 23 428 434 (Pubitemid 27502135)
-
(1997)
Diabetes and Metabolism
, vol.23
, Issue.5
, pp. 428-434
-
-
Balkau, B.1
Eschwege, E.2
Tichet, J.3
Marre, M.4
Simon, D.5
Alhenc-Gelas, F.6
Bechetoille, A.7
Gallois, Y.8
Girault, A.9
Marre, M.10
Brochier, M.11
Royer, B.12
Mermod, B.13
Le Mauff, J.M.14
Buruil, A.15
Arondel, D.16
Novak, M.17
Petrella, A.18
D'Hour, A.19
Lepinay, P.20
Calvet, C.21
Desclerc-Dulac, D.22
Aubourg, Ph.23
Cogneau, J.24
Rougeron, C.25
Diquero, V.26
Cohen, J.M.27
Caces, E.28
Cailleau, M.29
Jacquelin, J.M.30
Moreau, J.G.31
Rakotozafy, F.32
Tichet, J.33
Vol, S.34
more..
-
27
-
-
54249139116
-
Body composition analysis by leg-to-leg bioelectrical impedance and dual-energy X-ray absorptiometry in non-obese and obese individuals
-
Z Boneva-Asiova MA Boyanov 2008 Body composition analysis by leg-to-leg bioelectrical impedance and dual-energy X-ray absorptiometry in non-obese and obese individuals Diabetes Obes Metab 10 1012 1018
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 1012-1018
-
-
Boneva-Asiova, Z.1
Boyanov, M.A.2
-
28
-
-
57849169482
-
No apparent progress in bioelectrical impedance accuracy: Validation against metabolic risk and DXA
-
Hemmingsson E, Udden J, Neovius M (2009) No apparent progress in bioelectrical impedance accuracy: validation against metabolic risk and DXA. Obesity (Silver Spring) 17:183-187
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 183-187
-
-
Hemmingsson, E.1
Udden, J.2
Neovius, M.3
-
30
-
-
0015154543
-
Attributable risk percent in case-control studies
-
P Cole B MacMahon 1971 Attributable risk percent in case-control studies Br J Prev Soc Med 25 242 244
-
(1971)
Br J Prev Soc Med
, vol.25
, pp. 242-244
-
-
Cole, P.1
MacMahon, B.2
|