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Volumn 87, Issue 5, 2009, Pages 537-546

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations

(17)  Cauchi, Stéphane a   Stutzmann, Fanny a   Cavalcanti Proença, Christine a   Durand, Emmanuelle a   Pouta, Anneli b,c   Hartikainen, Anna Liisa b   Marre, Michel d,e,f   Vol, Sylviane g   Tammelin, Tuija h   Laitinen, Jaana h   Gonzalez Izquierdo, Arturo c   Blakemore, Alexandra If i   Elliott, Paul c   Meyre, David a   Balkau, Beverley d,j   Järvelin, Marjo Riitta b,c,k   Froguel, Philippe a,i  

d INSERM   (France)

Author keywords

Obesity; Population genetics; SNP

Indexed keywords

ADOLESCENT; ALLELE; ARTICLE; BODY MASS; CHILD; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; ENVIRONMENTAL FACTOR; FEMALE; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHENOTYPE; PHYSICAL ACTIVITY; POPULATION; PREVALENCE; SCHOOL CHILD; STATISTICAL SIGNIFICANCE;

EID: 67349103704     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-009-0451-6     Document Type: Article
Times cited : (137)

References (30)
  • 3
    • 41749090524 scopus 로고    scopus 로고
    • Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
    • A Hinney TT Nguyen A Scherag 2007 Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants PLoS ONE 2 e1361
    • (2007) PLoS ONE , vol.2 , pp. 1361
    • Hinney, A.1    Nguyen, T.T.2    Scherag, A.3
  • 4
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • RJ Loos CM Lindgren S Li 2008 Common variants near MC4R are associated with fat mass, weight and risk of obesity Nat Genet 40 768 775
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3
  • 6
    • 42049117134 scopus 로고    scopus 로고
    • The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks
    • Lopez-Bermejo A, Petry CJ, Diaz M et al (2008) The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab 93:1501-1505
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1501-1505
    • Lopez-Bermejo, A.1    Petry, C.J.2    Diaz, M.3
  • 7
    • 38449098674 scopus 로고    scopus 로고
    • Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
    • CH Andreasen KL Stender-Petersen MS Mogensen 2008 Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation Diabetes 57 95 101
    • (2008) Diabetes , vol.57 , pp. 95-101
    • Andreasen, C.H.1    Stender-Petersen, K.L.2    Mogensen, M.S.3
  • 8
    • 39949083566 scopus 로고    scopus 로고
    • Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes
    • JA Jacobsson P Danielsson V Svensson 2008 Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes Biochem Biophys Res Commun 368 476 482
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 476-482
    • Jacobsson, J.A.1    Danielsson, P.2    Svensson, V.3
  • 9
    • 51649099799 scopus 로고    scopus 로고
    • Physical activity and the association of common FTO gene variants with body mass index and obesity
    • E Rampersaud BD Mitchell TI Pollin 2008 Physical activity and the association of common FTO gene variants with body mass index and obesity Arch Intern Med 168 1791 1797
    • (2008) Arch Intern Med , vol.168 , pp. 1791-1797
    • Rampersaud, E.1    Mitchell, B.D.2    Pollin, T.I.3
  • 10
    • 40949123295 scopus 로고    scopus 로고
    • Insights from the genetics of severe childhood obesity
    • S Farooqi 2007 Insights from the genetics of severe childhood obesity Horm Res 68 Suppl 5 5 7
    • (2007) Horm Res 68 Suppl , vol.5 , pp. 5-7
    • Farooqi, S.1
  • 12
    • 39749116842 scopus 로고    scopus 로고
    • FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs
    • RA Price WD Li H Zhao 2008 FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs BMC Med Genet 9 4
    • (2008) BMC Med Genet , vol.9 , pp. 4
    • Price, R.A.1    Li, W.D.2    Zhao, H.3
  • 13
    • 40749094439 scopus 로고    scopus 로고
    • Variants in the FTO gene are associated with common obesity in the Belgian population
    • A Peeters S Beckers A Verrijken 2008 Variants in the FTO gene are associated with common obesity in the Belgian population Mol Genet Metab 93 481 484
    • (2008) Mol Genet Metab , vol.93 , pp. 481-484
    • Peeters, A.1    Beckers, S.2    Verrijken, A.3
  • 15
    • 51849111090 scopus 로고    scopus 로고
    • FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
    • SI Kring C Holst E Zimmermann 2008 FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness PLoS ONE 3 e2958
    • (2008) PLoS ONE , vol.3 , pp. 2958
    • Kring, S.I.1    Holst, C.2    Zimmermann, E.3
  • 16
    • 44749083224 scopus 로고    scopus 로고
    • Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI
    • RM Freathy NJ Timpson DA Lawlor 2008 Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI Diabetes 57 1419 1426
    • (2008) Diabetes , vol.57 , pp. 1419-1426
    • Freathy, R.M.1    Timpson, N.J.2    Lawlor, D.A.3
  • 17
    • 43049149732 scopus 로고    scopus 로고
    • Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
    • JK Hertel S Johansson H Raeder 2008 Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study) Diabetologia 51 971 977
    • (2008) Diabetologia , vol.51 , pp. 971-977
    • Hertel, J.K.1    Johansson, S.2    Raeder, H.3
  • 18
    • 50449104632 scopus 로고    scopus 로고
    • Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
    • MC Ng KS Park B Oh 2008 Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians Diabetes 57 2226 2233
    • (2008) Diabetes , vol.57 , pp. 2226-2233
    • Ng, M.C.1    Park, K.S.2    Oh, B.3
  • 19
    • 47749128415 scopus 로고    scopus 로고
    • Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
    • DK Sanghera L Ortega S Han 2008 Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk BMC Med Genet 9 59
    • (2008) BMC Med Genet , vol.9 , pp. 59
    • Sanghera, D.K.1    Ortega, L.2    Han, S.3
  • 20
    • 54949113309 scopus 로고    scopus 로고
    • The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change, and diabetes risk in women
    • Qi L, Kraft P, Hunter DJ et al (2008) The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change, and diabetes risk in women. Hum Mol Genet 17:3502-3508
    • (2008) Hum Mol Genet , vol.17 , pp. 3502-3508
    • Qi, L.1    Kraft, P.2    Hunter, D.J.3
  • 21
    • 47549107452 scopus 로고    scopus 로고
    • Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity
    • T Berentzen SI Kring C Holst 2008 Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity J Clin Endocrinol Metab 93 2904 2908
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2904-2908
    • Berentzen, T.1    Kring, S.I.2    Holst, C.3
  • 24
    • 52749092130 scopus 로고    scopus 로고
    • Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees
    • F Stutzmann K Tan V Vatin 2008 Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees Diabetes 57 2511 2518
    • (2008) Diabetes , vol.57 , pp. 2511-2518
    • Stutzmann, F.1    Tan, K.2    Vatin, V.3
  • 25
    • 0024594999 scopus 로고
    • Androgen regulation of proopiomelanocortin gene expression and peptide content in the basal hypothalamus
    • M Blum JL Roberts SL Wardlaw 1989 Androgen regulation of proopiomelanocortin gene expression and peptide content in the basal hypothalamus Endocrinology 124 2283 2288 (Pubitemid 19132028)
    • (1989) Endocrinology , vol.124 , Issue.5 , pp. 2283-2288
    • Blum, M.1    Roberts, J.L.2    Wardlaw, S.L.3
  • 27
    • 54249139116 scopus 로고    scopus 로고
    • Body composition analysis by leg-to-leg bioelectrical impedance and dual-energy X-ray absorptiometry in non-obese and obese individuals
    • Z Boneva-Asiova MA Boyanov 2008 Body composition analysis by leg-to-leg bioelectrical impedance and dual-energy X-ray absorptiometry in non-obese and obese individuals Diabetes Obes Metab 10 1012 1018
    • (2008) Diabetes Obes Metab , vol.10 , pp. 1012-1018
    • Boneva-Asiova, Z.1    Boyanov, M.A.2
  • 28
    • 57849169482 scopus 로고    scopus 로고
    • No apparent progress in bioelectrical impedance accuracy: Validation against metabolic risk and DXA
    • Hemmingsson E, Udden J, Neovius M (2009) No apparent progress in bioelectrical impedance accuracy: validation against metabolic risk and DXA. Obesity (Silver Spring) 17:183-187
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 183-187
    • Hemmingsson, E.1    Udden, J.2    Neovius, M.3
  • 30
    • 0015154543 scopus 로고
    • Attributable risk percent in case-control studies
    • P Cole B MacMahon 1971 Attributable risk percent in case-control studies Br J Prev Soc Med 25 242 244
    • (1971) Br J Prev Soc Med , vol.25 , pp. 242-244
    • Cole, P.1    MacMahon, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.