Transient forebrain over-expression of CRF induces plasma corticosterone and mild behavioural changes in adult conditional CRF transgenic mice

Pharmacology Biochemistry and Behavior

Volumn 93, Issue 1, 2009, Pages 17-24

  Vicentini, Elena ^a   Arban, Roberto ^a   Angelici, Ornella ^a   Maraia, Gabriella ^a   Perico, MariaElisa ^a   Mugnaini, Manolo ^a   Ugolini, Annarosa ^a   Large, Charles ^a   Domenici, Enrico ^a   Gerrard, Philip ^a   Bortner, Donna ^b   Mansuy, Isabelle M ^c   Mangiarini, Laura ^a   Merlo Pich, Emilio ^a  

^a GSK   (Italy)

^b GLAXOSMITHKLINE   (United States)

^c University of Zurich Brain Research Institute   (Switzerland)

Author keywords

Anxiety; CRF; Depression; Doxycycline; HPA axis; Transgenic mice

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; DOXYCYCLINE; MESSENGER RNA;

ACUTE STRESS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR CHANGE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DEXAMETHASONE SUPPRESSION TEST; EXERCISE TEST; FEMALE; FORCED SWIMMING TEST; FOREBRAIN; GENE; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HYPOTHALAMUS; LIGHT AND DARK TEST; MALE; MOUSE; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; RECURRENT DISEASE; TETO GENE; TRANSGENIC MOUSE;

ANIMALS; ANXIETY; BASE SEQUENCE; BEHAVIOR, ANIMAL; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DNA PRIMERS; FEMALE; GENE EXPRESSION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOOD DISORDERS; PROSENCEPHALON; RATS; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; SYNAPTIC TRANSMISSION;

MUS; MUS MUSCULUS;

EID: 67349092807     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.03.015     Document Type: Article

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