Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-α on Fanconi anemia hematopoietic stem and progenitor cells

Blood

Volumn 113, Issue 21, 2009, Pages 5111-5120

  Milsom, Michael D ^a   Schiedlmeier, Bernhard ^b   Bailey, Jeff ^c   Kim, Mi Ok ^c   Li, Dandan ^c   Jansen, Michael ^c   Ali, Abdullah Mahmood ^c   Kirby, Michelle ^c   Baum, Christopher ^b   Fairbairn, Leslie J ^d   Williams, David A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEOBOX PROTEIN HOXB4; HOMEODOMAIN PROTEIN; PROTEIN C; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG; FANCC PROTEIN, MOUSE; FANCONI ANEMIA GROUP C PROTEIN; HOXB4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ENGRAFTMENT; FANCONI ANEMIA; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; DRUG EFFECT; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MOUSE MUTANT; PATHOLOGY;

ANIMALS; APOPTOSIS; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP C PROTEIN; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; REACTIVE OXYGEN SPECIES; RECEPTORS, TUMOR NECROSIS FACTOR; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67149127139     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-09-180224     Document Type: Article

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