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Volumn 367, Issue 1895, 2009, Pages 2055-2078

A mathematical approach to bone Tissue engineering

Author keywords

Bone regeneration; Homogenization theory; Multiscale approach; Permeability computation

Indexed keywords

BIOLOGICAL MATERIALS; BONE; CAPILLARITY; COMPUTER SIMULATION; ENGINEERING; SCAFFOLDS;

EID: 67149109837     PISSN: 1364503X     EISSN: None     Source Type: Journal    
DOI: 10.1098/rsta.2009.0055     Document Type: Article
Times cited : (45)

References (70)
  • 1
    • 0031339119 scopus 로고    scopus 로고
    • Simulation of trabecular surface remodeling based on local stress nonuniformity
    • Adachi, T., Tomita, Y., Sakaue, H. and Tanaka, M. 1997 Simulation of trabecular surface remodeling based on local stress nonuniformity. JSME Int. Ser. C 40, 782-792.
    • (1997) JSME Int. Ser. C , vol.40 , pp. 782-792
    • Adachi, T.1    Tomita, Y.2    Sakaue, H.3    Tanaka, M.4
  • 2
    • 0034785612 scopus 로고    scopus 로고
    • Trabecular surface remodelling simulation for cancellous bone using microstructural voxel finite element models
    • doi:10.1115/1.1392315
    • Adachi, T., Tsubota, K. I., Tomita, Y. and Hollister, S. J. 2001 Trabecular surface remodelling simulation for cancellous bone using microstructural voxel finite element models. J. Biomech. Eng. 123, 403-409. (doi:10.1115/1.1392315)
    • (2001) J. Biomech. Eng , vol.123 , pp. 403-409
    • Adachi, T.1    Tsubota, K.I.2    Tomita, Y.3    Hollister, S.J.4
  • 3
    • 33646017698 scopus 로고    scopus 로고
    • Framework for optimal design of porous scaffold microstructure by computational simulation of bone regeneration
    • doi:10.1016/j.biomaterials.2006.02.039
    • Adachi, T., Osako, Y., Tanaka, M., Hojo, M. and Hollister, S. J. 2006 Framework for optimal design of porous scaffold microstructure by computational simulation of bone regeneration. Biomaterials 27, 3964-3972. (doi:10.1016/j.biomaterials.2006.02.039)
    • (2006) Biomaterials , vol.27 , pp. 3964-3972
    • Adachi, T.1    Osako, Y.2    Tanaka, M.3    Hojo, M.4    Hollister, S.J.5
  • 4
    • 56349120659 scopus 로고    scopus 로고
    • Computational mechanobiology to study the effect of surface geometry on peri-implant tissue differentiation
    • doi:10.1115/1.2970057
    • Andreykiv, A., van Keulen, F. and Prendergast, P. J. 2008 Computational mechanobiology to study the effect of surface geometry on peri-implant tissue differentiation. J. Biomech. Eng. 130, 051015. (doi:10.1115/1.2970057)
    • (2008) J. Biomech. Eng , vol.130 , pp. 051015
    • Andreykiv, A.1    van Keulen, F.2    Prendergast, P.J.3
  • 5
    • 0025486317 scopus 로고
    • An approach for time-dependent bone modelling and remodelling: Theoretical development
    • doi:10.1002 /jor.1100080506
    • Beaupré, G. S., Orr, T. E. and Carter, D. R. 1990 An approach for time-dependent bone modelling and remodelling: theoretical development. J. Orthop. Res. 8, 651-661. (doi:10.1002 /jor.1100080506)
    • (1990) J. Orthop. Res , vol.8 , pp. 651-661
    • Beaupré, G.S.1    Orr, T.E.2    Carter, D.R.3
  • 6
    • 0042925433 scopus 로고    scopus 로고
    • Cell organization in soft media due to active mechanosensing
    • doi:10.1073/pnas.1233544100
    • Bischofs, I. B. and Schwarz, U. S. 2003 Cell organization in soft media due to active mechanosensing. Proc. Natl Acad. Sci. USA 100, 9274-9279. (doi:10.1073/pnas.1233544100)
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 9274-9279
    • Bischofs, I.B.1    Schwarz, U.S.2
  • 7
    • 0031969585 scopus 로고    scopus 로고
    • Enhancement of bone formation in the setting of repeated tissue deformation
    • doi:10.1097/00003086- 199805000-00030
    • Bostrom, M. P. G., Aspenberg, P., Jeppsson, C. and Salvati, E. A. 1998 Enhancement of bone formation in the setting of repeated tissue deformation. Clin. Orthop. Relat. Res. 350, 221-228. (doi:10.1097/00003086- 199805000-00030)
    • (1998) Clin. Orthop. Relat. Res , vol.350 , pp. 221-228
    • Bostrom, M.P.G.1    Aspenberg, P.2    Jeppsson, C.3    Salvati, E.A.4
  • 8
    • 34247610805 scopus 로고    scopus 로고
    • Polymer scaffolds with interconnected spherical pores and controlled architecture for tissue engineering. Fabrication, mechanical properties and finite element modeling
    • doi:10.1002/jbm.b.30683
    • Brígido-Diego, R., Más-Estellés, J., Sanz, J. A., García-Aznar, J. M. and Salmerón-Sánchez, M. 2007 Polymer scaffolds with interconnected spherical pores and controlled architecture for tissue engineering. Fabrication, mechanical properties and finite element modeling. J. Biomed. Mater. Res. B 81b, 448-455. (doi:10.1002/jbm.b.30683)
    • (2007) J. Biomed. Mater. Res. B , vol.81 b , pp. 448-455
    • Brígido-Diego, R.1    Más-Estellés, J.2    Sanz, J.A.3    García-Aznar, J.M.4    Salmerón-Sánchez, M.5
  • 9
    • 35348975035 scopus 로고    scopus 로고
    • Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus and dissolution rate: Application of mechanobiological models in tissue engineering
    • doi:10.1016/j.biomaterials.2007.09.003
    • Byrne, D. P., Lacroix, D., Planell, J. A., Kelly, D. J. and Prendergast, P. J. 2007 Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus and dissolution rate: application of mechanobiological models in tissue engineering. Biomaterials 28, 5544-5554. (doi:10.1016/j.biomaterials.2007.09.003)
    • (2007) Biomaterials , vol.28 , pp. 5544-5554
    • Byrne, D.P.1    Lacroix, D.2    Planell, J.A.3    Kelly, D.J.4    Prendergast, P.J.5
  • 10
    • 0023162010 scopus 로고
    • Trabecular bone density and loading history: Regulation of connective tissue biology by mechanical energy
    • doi:10. 1016/0021-9290 (87) 90058-3
    • Carter, D. R., Fyhrie, D. P. and Whalen, R. T. 1987 Trabecular bone density and loading history: regulation of connective tissue biology by mechanical energy. J. Biomech. 20, 785-794. (doi:10. 1016/0021-9290 (87) 90058-3)
    • (1987) J. Biomech , vol.20 , pp. 785-794
    • Carter, D.R.1    Fyhrie, D.P.2    Whalen, R.T.3
  • 11
    • 0024566948 scopus 로고
    • Relationships between loading history and femoral cancellous bone architecture
    • doi:10.1016/0021-9290 (89) 90091-2
    • Carter, D. R., Orr, T. E. and Fyhrie, D. P. 1989 Relationships between loading history and femoral cancellous bone architecture. J. Biomech. 22, 231-244. (doi:10.1016/0021-9290 (89) 90091-2)
    • (1989) J. Biomech , vol.22 , pp. 231-244
    • Carter, D.R.1    Orr, T.E.2    Fyhrie, D.P.3
  • 12
    • 0016974131 scopus 로고
    • Bone remodeling I: A theory of adaptive elasticity
    • doi:10.1007/ BF00041724
    • Cowin, S. C. and Hegedus, D. H. 1976 Bone remodeling I: a theory of adaptive elasticity. J. Elast. 6, 313-326. (doi:10.1007/ BF00041724)
    • (1976) J. Elast , vol.6 , pp. 313-326
    • Cowin, S.C.1    Hegedus, D.H.2
  • 13
    • 0025886995 scopus 로고
    • Mathematical model for the effects of adhesion and mechanics on cell migration speed
    • doi:10.1016/S0006-3495 (91) 82027-6
    • DiMilla, P. A., Barbee, K. and Lauffenburger, D. A. 1991 Mathematical model for the effects of adhesion and mechanics on cell migration speed. Biophys. J. 60, 15-37. (doi:10.1016/S0006-3495 (91) 82027-6)
    • (1991) Biophys. J , vol.60 , pp. 15-37
    • DiMilla, P.A.1    Barbee, K.2    Lauffenburger, D.A.3
  • 14
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • doi:10.1126/science.1116995
    • Discher, D. E., Janmey, P. and Wang, Y. L. 2005 Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139-1143. (doi:10.1126/science.1116995)
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.L.3
  • 16
    • 0347319161 scopus 로고    scopus 로고
    • Substrate compliance versus ligand density in cell on gel responses
    • S0006-3495 (04) 74140-5, doi:10.1016
    • Engler, A., Bacakova, L., Newman, C., Hategan, A., Griffin, M. and Discher, D. 2004 Substrate compliance versus ligand density in cell on gel responses. Biophys. J. 86, 617-628. (doi:10.1016 /S0006-3495 (04) 74140-5)
    • (2004) Biophys. J , vol.86 , pp. 617-628
    • Engler, A.1    Bacakova, L.2    Newman, C.3    Hategan, A.4    Griffin, M.5    Discher, D.6
  • 17
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • doi:10.1016/j.cell.2006.06.044
    • Engler, A. J., Sen, S., Sweeney, H. L. and Discher, D. E. 2007 Matrix elasticity directs stem cell lineage specification. Cell 126, 677-689. (doi:10.1016/j.cell.2006.06.044)
    • (2007) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 18
    • 34548085955 scopus 로고    scopus 로고
    • Facilitated endogenous repair: Making tissue engineering simple, practical, and economical
    • doi:10.1089/ten. 2006.0302
    • Evans, C. H. et al. 2007 Facilitated endogenous repair: making tissue engineering simple, practical, and economical. Tissue Eng. 13, 1987-1993. (doi:10.1089/ten. 2006.0302)
    • (2007) Tissue Eng , vol.13 , pp. 1987-1993
    • Evans, C.H.1
  • 19
    • 0038731228 scopus 로고    scopus 로고
    • Tissue engineering: Current state of clinical application
    • doi:10.1097/00008480-200306000-00007
    • Fauza, D. O. 2003 Tissue engineering: current state of clinical application. Curr. Opin. Pediatr. 15, 267-271. (doi:10.1097/00008480-200306000-00007)
    • (2003) Curr. Opin. Pediatr , vol.15 , pp. 267-271
    • Fauza, D.O.1
  • 21
    • 17844405556 scopus 로고    scopus 로고
    • In vivo bone regeneration with injectable calcium phosphate biomaterial: A three-dimensional micro-computed tomographic, biomechanical and SEM study
    • doi:10.1016/j.biomaterials.2005.01.072
    • Gauthier, O., Müller, R., von Stechow, D., Lamy, B., Weiss, P., Bouler, J. M., Aguado, E. and Daculsi, G. 2005 In vivo bone regeneration with injectable calcium phosphate biomaterial: a three-dimensional micro-computed tomographic, biomechanical and SEM study. Biomaterials 26, 5444-5453. (doi:10.1016/j.biomaterials.2005.01.072)
    • (2005) Biomaterials , vol.26 , pp. 5444-5453
    • Gauthier, O.1    Müller, R.2    von Stechow, D.3    Lamy, B.4    Weiss, P.5    Bouler, J.M.6    Aguado, E.7    Daculsi, G.8
  • 22
    • 33750476655 scopus 로고    scopus 로고
    • Cell adaptationto a physiologically relevant ECM mimic with different viscoelastic properties
    • doi:10.1016/j.biomaterials.2006.09.038
    • Ghosh, K., Pan, Z., Guan, E., Ge, S., Liu, Y., Nakamura, T., Ren, X., Rafailovich, M. and Clark, R. A. F. 2007 Cell adaptationto a physiologically relevant ECM mimic with different viscoelastic properties. Biomaterials 28, 671-679. (doi:10.1016/j.biomaterials.2006.09.038)
    • (2007) Biomaterials , vol.28 , pp. 671-679
    • Ghosh, K.1    Pan, Z.2    Guan, E.3    Ge, S.4    Liu, Y.5    Nakamura, T.6    Ren, X.7    Rafailovich, M.8    Clark, R.A.F.9
  • 23
    • 0031554171 scopus 로고    scopus 로고
    • Polymer bulk erosion
    • doi:10.1021 /ma961627y
    • Gopferich, A. 1997 Polymer bulk erosion. Macromolecules 30, 2598-2604. (doi:10.1021 /ma961627y)
    • (1997) Macromolecules , vol.30 , pp. 2598-2604
    • Gopferich, A.1
  • 24
    • 21844461292 scopus 로고    scopus 로고
    • Rabbit knee joint biomechanics: Motion analysis and modeling of forces during hopping
    • doi:10.1016/j.orthres. 2005.01.005
    • Gushue, D. L., Houck, J. and Lerner, A. M. 2005 Rabbit knee joint biomechanics: motion analysis and modeling of forces during hopping. J. Orthop. Res. 23, 735-742. (doi:10.1016/j.orthres. 2005.01.005)
    • (2005) J. Orthop. Res , vol.23 , pp. 735-742
    • Gushue, D.L.1    Houck, J.2    Lerner, A.M.3
  • 25
    • 85020801068 scopus 로고    scopus 로고
    • HKS 2001 AIBAQUSi user's manual. v. 6.2. Pawtucket, RI: HKS Inc. See http://www.simulia.com to where ABAQUS has moved.
    • HKS 2001 AIBAQUSi user's manual. v. 6.2. Pawtucket, RI: HKS Inc. See http://www.simulia.com to where ABAQUS has moved.
  • 26
    • 0035988665 scopus 로고    scopus 로고
    • Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints
    • doi:10. 1016/S0142-9612 (02) 00148-5
    • Hollister, S. J., Maddox, R. D. and Taboas, J. M. 2002 Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints. Biomaterials 23, 4095-4103. (doi:10. 1016/S0142-9612 (02) 00148-5)
    • (2002) Biomaterials , vol.23 , pp. 4095-4103
    • Hollister, S.J.1    Maddox, R.D.2    Taboas, J.M.3
  • 27
    • 0023510231 scopus 로고
    • Adaptive bone-remodeling theory applied to prosthetic-design analysis
    • doi:10.1016/0021-9290 (87) 90030-3
    • Huiskes, R., Weinans, H., Grootenboer, H. J., Dalstra, M., Fudala, B. and Sloof, T. J. 1987 Adaptive bone-remodeling theory applied to prosthetic-design analysis. J. Biomech. 20, 1135-1150. (doi:10.1016/0021-9290 (87) 90030-3)
    • (1987) J. Biomech , vol.20 , pp. 1135-1150
    • Huiskes, R.1    Weinans, H.2    Grootenboer, H.J.3    Dalstra, M.4    Fudala, B.5    Sloof, T.J.6
  • 28
    • 0034672872 scopus 로고    scopus 로고
    • Scaffolds in tissue engineering bone and cartilage
    • doi:10.1016/S0142-9612 (00) 00121-6
    • Hutmacher, D. W. 2000 Scaffolds in tissue engineering bone and cartilage. Biomaterials 21, 2529-2543. (doi:10.1016/S0142-9612 (00) 00121-6)
    • (2000) Biomaterials , vol.21 , pp. 2529-2543
    • Hutmacher, D.W.1
  • 29
    • 0032144180 scopus 로고    scopus 로고
    • Threedimensional culture of rat calvarial osteoblasts in porous biodegradable polymers
    • doi:10.1016/S0142-9612 (98) 00021-0
    • Ishaug-Riley, S. L., Crane-Kruger, G. M., Yaszemski, M. J. and Mikos, A. G. 1998 Threedimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials 19, 1405-1412. (doi:10.1016/S0142-9612 (98) 00021-0)
    • (1998) Biomaterials , vol.19 , pp. 1405-1412
    • Ishaug-Riley, S.L.1    Crane-Kruger, G.M.2    Yaszemski, M.J.3    Mikos, A.G.4
  • 31
    • 0031365852 scopus 로고    scopus 로고
    • Design of macroporous biodegradable polymer scaffolds for cell transplantation
    • Jerome, R. and Maquet, V. 1997 Design of macroporous biodegradable polymer scaffolds for cell transplantation. Mater. Sci. Forum 250, 15-42.
    • (1997) Mater. Sci. Forum , vol.250 , pp. 15-42
    • Jerome, R.1    Maquet, V.2
  • 32
    • 17844400927 scopus 로고    scopus 로고
    • Porosity of 3D biomaterial scaffolds and osteogenesis
    • doi:10.1016/j.biomaterials.2005.02.002
    • Karageorgiou, V. and Kaplan, D. 2005 Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26, 5474-5491. (doi:10.1016/j.biomaterials.2005.02.002)
    • (2005) Biomaterials , vol.26 , pp. 5474-5491
    • Karageorgiou, V.1    Kaplan, D.2
  • 33
    • 33750625135 scopus 로고    scopus 로고
    • Prediction of the optimal mechanical properties for a scaffold used in osteochondral defect repair
    • doi:10.1089/ten, 12.2509
    • Kelly, D. J. and Prendergast, P. J. 2006 Prediction of the optimal mechanical properties for a scaffold used in osteochondral defect repair. Tissue Eng. 12, 2509-2519. (doi:10.1089/ten. 2006. 12.2509)
    • (2006) Tissue Eng , vol.12 , pp. 2509-2519
    • Kelly, D.J.1    Prendergast, P.J.2
  • 34
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • doi:10.1126/science. 1069492
    • Kitano, H. 2002 Systems biology: a brief overview. Science 295, 1662-1664. (doi:10.1126/science. 1069492)
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 35
    • 0005665739 scopus 로고    scopus 로고
    • Geometry of carriers controlling phenotypic expression in BMP-induced osteogenesis and chondrogenesis
    • Kuboki, Y., Jin, Q. and Takita, H. 2001 Geometry of carriers controlling phenotypic expression in BMP-induced osteogenesis and chondrogenesis. J. Bone Joint Surg. Am. 83A, S105-S115.
    • (2001) J. Bone Joint Surg. Am , vol.83 A
    • Kuboki, Y.1    Jin, Q.2    Takita, H.3
  • 36
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: A physically integrated molecular process
    • doi:10.1016/S0092-8674 (00) 81280-5
    • Lauffenburger, D. A. and Horwitz, A. F. 1996 Cell migration: a physically integrated molecular process. Cell 84, 359-369. (doi:10.1016/S0092-8674 (00) 81280-5)
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 37
    • 0016483666 scopus 로고
    • A comparison of iliac marrow and biodegradable ceramic in periodontal defects
    • doi:10.1002 /jbm.820090207
    • Levin, M. P., Getter, L. and Cutright, D. E. 1975 A comparison of iliac marrow and biodegradable ceramic in periodontal defects. J. Biomed. Mater. Res. 9, 183-195. (doi:10.1002 /jbm.820090207)
    • (1975) J. Biomed. Mater. Res , vol.9 , pp. 183-195
    • Levin, M.P.1    Getter, L.2    Cutright, D.E.3
  • 38
    • 1842419423 scopus 로고    scopus 로고
    • A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity
    • doi:10.1016/j.jbiomech.2003.09.029
    • Lin, C. Y., Kikuchi, N. and Hollister, S. J. 2004 A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity. J. Biomech. 37, 623-636. (doi:10.1016/j.jbiomech.2003.09.029)
    • (2004) J. Biomech , vol.37 , pp. 623-636
    • Lin, C.Y.1    Kikuchi, N.2    Hollister, S.J.3
  • 39
    • 33845326442 scopus 로고    scopus 로고
    • The Turing model comes of molecular age
    • doi:10.1126/science. 1136396
    • Maini, P. K., Baker, R. E. and Chuong, C. M. 2006 The Turing model comes of molecular age. Science 314, 1397-1398. (doi:10.1126/science. 1136396)
    • (2006) Science , vol.314 , pp. 1397-1398
    • Maini, P.K.1    Baker, R.E.2    Chuong, C.M.3
  • 40
    • 85020788956 scopus 로고    scopus 로고
    • Materialise 2006 MIMICS, v. 10.0. Materialise NV, Leuven, Belgium. See http://www.materialise.com.
    • Materialise 2006 MIMICS, v. 10.0. Materialise NV, Leuven, Belgium. See http://www.materialise.com.
  • 41
    • 41549123518 scopus 로고    scopus 로고
    • Modeling mechanosensing and its effect on the migration and proliferation of adherent cells
    • doi:10.1016/j.actbio. 2007.10.014
    • Moreo, P., García-Aznar, J. M. and Doblaré, M. 2008 Modeling mechanosensing and its effect on the migration and proliferation of adherent cells. Acta Biomater. 4, 613-621. (doi:10.1016/j.actbio. 2007.10.014)
    • (2008) Acta Biomater , vol.4 , pp. 613-621
    • Moreo, P.1    García-Aznar, J.M.2    Doblaré, M.3
  • 42
    • 4344596239 scopus 로고    scopus 로고
    • Cell mechanosensitivity controls the anisotropy of focal adhesions
    • doi:10.1073/pnas. 0403539101
    • Nicolas, A., Geiger, B. and Safran, S. A. 2004 Cell mechanosensitivity controls the anisotropy of focal adhesions. Proc. Natl Acad. Sci. USA 101, 12 520-12 525. (doi:10.1073/pnas. 0403539101)
    • (2004) Proc. Natl Acad. Sci. USA , vol.101
    • Nicolas, A.1    Geiger, B.2    Safran, S.A.3
  • 44
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • doi:10.1073/pnas.94.25.13661
    • Pelham, R. J. and Wang, Y. 1997 Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl Acad. Sci. USA 94, 13 661-13 665. (doi:10.1073/pnas.94.25.13661)
    • (1997) Proc. Natl Acad. Sci. USA , vol.94
    • Pelham, R.J.1    Wang, Y.2
  • 45
    • 22544467793 scopus 로고    scopus 로고
    • Pothuaud, L., Fricain, J. C., Pallu, S., Bareille, R., Renard, M., Durrieu, M. C., Dard, M., Vernizeau, M. and Amédé, J. 2005 Mathematical modelling of the distribution of newly formed bone in bone tissue engineering. Biomaterials 26, 6788-6797. (doi:10.1016/j. biomaterials.2005. 04.002)
    • Pothuaud, L., Fricain, J. C., Pallu, S., Bareille, R., Renard, M., Durrieu, M. C., Dard, M., Vernizeau, M. and Amédé, J. 2005 Mathematical modelling of the distribution of newly formed bone in bone tissue engineering. Biomaterials 26, 6788-6797. (doi:10.1016/j. biomaterials.2005. 04.002)
  • 46
    • 0031157459 scopus 로고    scopus 로고
    • Biophysical stimuli on cells during tissue differentiation at implant interfaces
    • doi:10.1016/S0021-9290 (96) 00140-6
    • Prendergast, P. J., Huiskes, R. and Søballe, K. 1997 Biophysical stimuli on cells during tissue differentiation at implant interfaces. J. Biomech. 30, 539-548. (doi:10.1016/S0021-9290 (96) 00140-6)
    • (1997) J. Biomech , vol.30 , pp. 539-548
    • Prendergast, P.J.1    Huiskes, R.2    Søballe, K.3
  • 47
    • 0017365909 scopus 로고
    • Tri-calcium phosphate as a bone substitute
    • Rejda, B. V., Peelen, J. G. and de Groot, K. 1977 Tri-calcium phosphate as a bone substitute. J. Bioeng. 1, 93-97.
    • (1977) J. Bioeng , vol.1 , pp. 93-97
    • Rejda, B.V.1    Peelen, J.G.2    de Groot, K.3
  • 48
    • 44749083252 scopus 로고    scopus 로고
    • Micro-macro numerical modelling of bone regeneration in tissue engineering
    • doi:10.1016/j.cma.2008.02.010
    • Sanz-Herrera, J. A., García-Aznar, J. M. and Doblaŕe, M. 2008a Micro-macro numerical modelling of bone regeneration in tissue engineering. Comput. Methods Appl. Mech. Eng. 197, 3092-3107. (doi:10.1016/j.cma.2008.02.010)
    • (2008) Comput. Methods Appl. Mech. Eng , vol.197 , pp. 3092-3107
    • Sanz-Herrera, J.A.1    García-Aznar, J.M.2    Doblaŕe, M.3
  • 49
    • 50149101582 scopus 로고    scopus 로고
    • A mathematical model for bone tissue regeneration inside a specific type of scaffold
    • doi:10.1007/s10237-007-0089-7
    • Sanz-Herrera, J. A., García-Aznar, J. M. and Doblaré, M. 2008b A mathematical model for bone tissue regeneration inside a specific type of scaffold. Biomech. Model. Mechanobiol. 7, 355-366. (doi:10.1007/s10237-007-0089-7)
    • (2008) Biomech. Model. Mechanobiol , vol.7 , pp. 355-366
    • Sanz-Herrera, J.A.1    García-Aznar, J.M.2    Doblaré, M.3
  • 51
    • 56349136287 scopus 로고    scopus 로고
    • On scaffold designing for bone regeneration: A computational multiscale approach
    • doi:10.1016 /j.actbio.2008.06.021
    • Sanz-Herrera, J. A., García-Aznar, J. M. and Doblaré, M. 2009 On scaffold designing for bone regeneration: a computational multiscale approach. Acta Biomater. 5, 219-229. (doi:10.1016 /j.actbio.2008.06.021)
    • (2009) Acta Biomater , vol.5 , pp. 219-229
    • Sanz-Herrera, J.A.1    García-Aznar, J.M.2    Doblaré, M.3
  • 52
    • 34247487902 scopus 로고    scopus 로고
    • The performance of poly-ε- caprolactone scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4
    • doi:10. 1016/j.biomaterials.2007.03.011
    • Savarino, L. et al. 2007 The performance of poly-ε- caprolactone scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4. Biomaterials 28, 3101-3109. (doi:10. 1016/j.biomaterials.2007.03.011)
    • (2007) Biomaterials , vol.28 , pp. 3101-3109
    • Savarino, L.1
  • 53
    • 32044449220 scopus 로고    scopus 로고
    • Focal adhesions as mechanosensors: The twospring model
    • doi:10.1016/j.biosystems.2005.05.019
    • Schwarz, U. S., Erdmann, T. and Bischofs, I. B. 2006 Focal adhesions as mechanosensors: the twospring model. Biosystems 83, 225-232. (doi:10.1016/j.biosystems.2005.05.019)
    • (2006) Biosystems , vol.83 , pp. 225-232
    • Schwarz, U.S.1    Erdmann, T.2    Bischofs, I.B.3
  • 54
    • 33846330965 scopus 로고    scopus 로고
    • Sengers, B. G., Taylor, M., Please, C. P. and Oreffo, R. O. C. 2007 Computational modelling of cell spreading and tissue regeneration in porous scaffolds. Biomaterials 28, 1926-1940. (doi:10.1016 /j.biomaterials.2006.12.008)
    • Sengers, B. G., Taylor, M., Please, C. P. and Oreffo, R. O. C. 2007 Computational modelling of cell spreading and tissue regeneration in porous scaffolds. Biomaterials 28, 1926-1940. (doi:10.1016 /j.biomaterials.2006.12.008)
  • 55
    • 85020784391 scopus 로고    scopus 로고
    • Sharc 2006 HARPOON. Sharc Ltd, Manchester, UK. See http://www.sharc.co.uk.
    • Sharc 2006 HARPOON. Sharc Ltd, Manchester, UK. See http://www.sharc.co.uk.
  • 56
    • 0035136691 scopus 로고    scopus 로고
    • Simmons, C. A., Meguid, S. A. and Pilliar, R. M. 2001 Mechanical regulation of localized and appositional bone formation around bone-interfacing implants. J. Biomed. Mater. Res. 55, 63-71. (doi:10.1002/1097-4636 (200104) 55:1<63::AID-JBM90>3.0. CO;2-V)
    • Simmons, C. A., Meguid, S. A. and Pilliar, R. M. 2001 Mechanical regulation of localized and appositional bone formation around bone-interfacing implants. J. Biomed. Mater. Res. 55, 63-71. (doi:10.1002/1097-4636 (200104) 55:1<63::AID-JBM90>3.0. CO;2-V)
  • 57
    • 2442426201 scopus 로고    scopus 로고
    • Sung, H. J., Meredith, C., Johnson, C. and Galis, Z. S. 2004 The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis. Biomaterials 25, 5735-5742. (doi:10.1016 /j.biomaterials.2004.01. 066)
    • Sung, H. J., Meredith, C., Johnson, C. and Galis, Z. S. 2004 The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis. Biomaterials 25, 5735-5742. (doi:10.1016 /j.biomaterials.2004.01. 066)
  • 58
    • 0003221647 scopus 로고
    • Elements of homogenization for inelastic solid mechanics
    • Homogenization techniques for composite media eds E. Sánchez-Palencia and A. Zaoui, Berlin, Germany: Springer, doi:10.1007/3-540-17616-0-15
    • Suquet, P. M. 1987 Elements of homogenization for inelastic solid mechanics. In Homogenization techniques for composite media (eds E. Sánchez-Palencia and A. Zaoui). Lecture Notes in Physics, vol. 272, pp. 193-278. Berlin, Germany: Springer. (doi:10.1007/3-540-17616-0-15)
    • (1987) Lecture Notes in Physics , vol.272 , pp. 193-278
    • Suquet, P.M.1
  • 59
    • 34249864531 scopus 로고    scopus 로고
    • Biomechanics and biophysics of cancer cells
    • doi:10. 1016/j.actbio.2007.04.002
    • Suresh, S. 2007 Biomechanics and biophysics of cancer cells. Acta Biomater. 3, 413-438. (doi:10. 1016/j.actbio.2007.04.002)
    • (2007) Acta Biomater , vol.3 , pp. 413-438
    • Suresh, S.1
  • 60
    • 0037210053 scopus 로고    scopus 로고
    • Indirect solid free form fabrication of local and global porous, biomimetic and composite 3D polymer-ceramic scaffolds
    • doi:10.1016/S0142-9612 (02) 00276-4
    • Taboas, J. M., Maddox, R. D., Krebsbach, P. H. and Hollister, S. J. 2003 Indirect solid free form fabrication of local and global porous, biomimetic and composite 3D polymer-ceramic scaffolds. Biomaterials 24, 181-194. (doi:10.1016/S0142-9612 (02) 00276-4)
    • (2003) Biomaterials , vol.24 , pp. 181-194
    • Taboas, J.M.1    Maddox, R.D.2    Krebsbach, P.H.3    Hollister, S.J.4
  • 61
    • 33646049364 scopus 로고    scopus 로고
    • Effects of different magnitudes of mechanical strain on osteoblasts in vitro
    • doi:10.1016/j.bbrc.2006. 03.123
    • Tang, L., Lin, Z. and Yong-Ming, L. 2006 Effects of different magnitudes of mechanical strain on osteoblasts in vitro. Biochem. Biophys. Res. Commun. 344, 122-128. (doi:10.1016/j.bbrc.2006. 03.123)
    • (2006) Biochem. Biophys. Res. Commun , vol.344 , pp. 122-128
    • Tang, L.1    Lin, Z.2    Yong-Ming, L.3
  • 62
    • 0035919604 scopus 로고    scopus 로고
    • A class of general algorithms for multi-scale analyses of heterogeneous media
    • doi:10.1016/S0045-7825 (01) 00179-7
    • Terada, K. and Kikuchi, N. 2001 A class of general algorithms for multi-scale analyses of heterogeneous media. Comput. Methods Appl. Mech. 190, 5427-5464. (doi:10.1016/S0045-7825 (01) 00179-7)
    • (2001) Comput. Methods Appl. Mech , vol.190 , pp. 5427-5464
    • Terada, K.1    Kikuchi, N.2
  • 63
    • 0031650325 scopus 로고    scopus 로고
    • Characterization of the mechanical behaviours of solid-fluid mixture by the homogenization method
    • doi:10. 1016/S0045-7825 (97) 00071-6
    • Terada, K., Ito, T. and Kikuchi, N. 1998 Characterization of the mechanical behaviours of solid-fluid mixture by the homogenization method. Comput. Methods Appl. Mech. 153, 223-257. (doi:10. 1016/S0045-7825 (97) 00071-6)
    • (1998) Comput. Methods Appl. Mech , vol.153 , pp. 223-257
    • Terada, K.1    Ito, T.2    Kikuchi, N.3
  • 64
    • 0031045696 scopus 로고    scopus 로고
    • Pore size of porous hydroxyapatite as the cell-substratum controls BMP-induced osteogenesis
    • Tsuruga, E., Takita, H., Itoh, H., Wakisaka, Y. and Kuboki, Y. 1997 Pore size of porous hydroxyapatite as the cell-substratum controls BMP-induced osteogenesis. J. Biochem. 12, 317-324.
    • (1997) J. Biochem , vol.12 , pp. 317-324
    • Tsuruga, E.1    Takita, H.2    Itoh, H.3    Wakisaka, Y.4    Kuboki, Y.5
  • 65
    • 0028066776 scopus 로고
    • Mechanical loading thresholds for lamellar and woven bone formation
    • Turner, C. H., Forwood, M. R., Rho, J. and Yoshikawa, T. 1994 Mechanical loading thresholds for lamellar and woven bone formation. J. Bone Miner. Res. 9, 87-97.
    • (1994) J. Bone Miner. Res , vol.9 , pp. 87-97
    • Turner, C.H.1    Forwood, M.R.2    Rho, J.3    Yoshikawa, T.4
  • 66
    • 0036027557 scopus 로고    scopus 로고
    • Effect of load on the early incorporation of impacted morsellized allografts
    • doi:10.1016/S0142-9612 (01) 00108-9
    • van der Donk, S., Buma, P., Verdonschot, N. and Schreurs, B. W. 2002 Effect of load on the early incorporation of impacted morsellized allografts. Biomaterials 23, 297-303. (doi:10.1016/S0142-9612 (01) 00108-9)
    • (2002) Biomaterials , vol.23 , pp. 297-303
    • van der Donk, S.1    Buma, P.2    Verdonschot, N.3    Schreurs, B.W.4
  • 67
    • 44349160618 scopus 로고    scopus 로고
    • Wang, Y., Pan, J., Han, X., Sinka, C. and Ding, L. 2008 A phenomenological model for the degradation of biodegradable polymers. Biomaterials 29, 3393-3401. (doi:10.1016 /j.biomaterials.2008.04. 042)
    • Wang, Y., Pan, J., Han, X., Sinka, C. and Ding, L. 2008 A phenomenological model for the degradation of biodegradable polymers. Biomaterials 29, 3393-3401. (doi:10.1016 /j.biomaterials.2008.04. 042)
  • 68
    • 0023764529 scopus 로고
    • Influence of physical activity on the regulation of bone density
    • doi:10.1016/0021-9290 (88) 90015-2
    • Whalen, R. T. and Carter, D. R. 1988 Influence of physical activity on the regulation of bone density. J. Biomech. 21, 825-837. (doi:10.1016/0021-9290 (88) 90015-2)
    • (1988) J. Biomech , vol.21 , pp. 825-837
    • Whalen, R.T.1    Carter, D.R.2
  • 69
    • 0037418433 scopus 로고    scopus 로고
    • Directed movement of vascular smooth muscle cells on gradient-compliant hydrogels
    • doi:10.1021 /la026403p
    • Wong, J. Y., Velasco, A., Rajagopalan, P. and Pham, Q. 2003 Directed movement of vascular smooth muscle cells on gradient-compliant hydrogels. Langmuir 19, 1908-1913. (doi:10.1021 /la026403p)
    • (2003) Langmuir , vol.19 , pp. 1908-1913
    • Wong, J.Y.1    Velasco, A.2    Rajagopalan, P.3    Pham, Q.4
  • 70
    • 23244456797 scopus 로고    scopus 로고
    • Computational model for cell migration in three-dimensional matrices
    • doi:10.1529 /biophysj.105.060723
    • Zaman, M. H., Kamm, R. D., Matsudaira, P. and Lauffenburger, D. A. 2005 Computational model for cell migration in three-dimensional matrices. Biophys. J. 89, 1389-1397. (doi:10.1529 /biophysj.105.060723)
    • (2005) Biophys. J , vol.89 , pp. 1389-1397
    • Zaman, M.H.1    Kamm, R.D.2    Matsudaira, P.3    Lauffenburger, D.A.4


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