Prediction of the optimal mechanical properties for a scaffold used in osteochondral defect repair

Tissue Engineering

Volumn 12, Issue 9, 2006, Pages 2509-2519

  Kelly, Daniel J ^a   Prendergast, Patrick J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHMS; CARTILAGE; CYCLIC LOADS; FINITE ELEMENT METHOD; MECHANICAL PROPERTIES; NUTRITION;

NUTRIENT TRANSPORT; OPTIMAL MECHANICAL PROPERTIES; OSTEOCHONDRAL DEFECT; THRESHOLD STIFFNESS;

BIOMEDICAL ENGINEERING;

ALGORITHM; ARTICLE; BIOMECHANICS; CARTILAGE; CARTILAGE CELL; CELL STIMULATION; CHONDROGENESIS; FINITE ELEMENT ANALYSIS; IN VITRO STUDY; NUTRIENT; PERMEABILITY; PRIORITY JOURNAL; REGULATORY MECHANISM; RIGIDITY; TISSUE DIFFERENTIATION; TISSUE ENGINEERING; TISSUE REGENERATION; WEIGHT BEARING; YOUNG MODULUS; ANIMAL; BIOLOGICAL MODEL; BONE REGENERATION; BONE REMODELING; COMPRESSIVE STRENGTH; HUMAN; INJURY; KNEE; METABOLISM;

ANIMALS; BONE REGENERATION; BONE REMODELING; CARTILAGE; CHONDROGENESIS; COMPRESSIVE STRENGTH; FINITE ELEMENT ANALYSIS; HUMANS; KNEE JOINT; MODELS, BIOLOGICAL; WEIGHT-BEARING;

EID: 33750625135     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2006.12.2509     Document Type: Article

References (36)

1. Freed, L.E., Marquis, J.C., Nohria, A., Emmanual, J., Mikos, A.G., and Langer, R. Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers. J. Biomed. Mater. Res. 27, 11, 1993.
2. Grande, D.A., Halberstadt, C., Naughton, G., Schwartz, R., and Manji, R. Evaluation of the matrix scaffolds for tissue engineering of articular cartilage grafts. J. Biomed. Mater. Res. 34, 211, 1997.
3. Rahman, M.S., and Tsuchiya, T. Enhancement of chondrogenic differentiation of human articular chondrocytes by biodegradable polymers. Tissue Eng. 7, 781, 2001.
4. Kimura, T., Yasui, N., Ohsawa, S., and Ono, K. Chondrocytes embedded in collagen gels maintain cartilage phenotype during long-term cultures. Clin. Orthop. Relat. Res. 186, 231, 1984.
5. Van Susante, J.L.C., Buma, P., Van Osch, G.J.V.M, Versleyen, D., Van der Kraan, P.M., Van der Berg, W.B., and Homminga, G.N. Culture of chondrocytes in alginate and collagen carrier gels. Acta Orthop. Scand. 66, 549, 1995.
6. Benya, P., and Schaffer, J. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30, 215, 1982.
7. Wakitani, S., Goto, T., and Pineda, S.J. Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J. Bone Joint Surg. 76-A, 579, 1994.
8. Rahfoth, B., Weisser, J., Sternkopf, F., Aigner, T., and von der Mark, K. Transplantation of allograft chondrocytes embedded in agarose gel into cartilage defects in rabbits. Osteoarth. Cart. 6, 50, 1998.
9. Niederauer, G.G., Slivka, M.A., Leatherbury, N.C., Korvick, D.L., Harroff, H.H., Ehler, W.C., Dunn, C.J., and Kieswetter, K. Evaluation of multiphase implants for repair of focal osteochondral defects in goats. Biomaterials 21, 2561, 2000.
10. Wakitani, S., Goto, T., Young, R.G., Mansour, J.M., Goldberg, V.C., and Caplan, A.C. Repair of large full-thickness articular cartilage defects with allograft articular chondrocytes in a collagen gel. Tissue Eng. 4, 429, 1998.
11. Liu, Y., Chen, F., Liu, W., Cui, L., and Shang, Q. Repairing large porcine full-thickness defects of articular cartilage using autologous chondrocyte-engineered cartilage. Tissue Eng. 8, 709, 2002.
12. Schaefer, D., Martin, I., Jundt, G., Seidel, J., Heberer, M., Grodzinsky, A., Bergin, I., Vunjak-Novakovic, G., and Freed, L.E. Tissue-engineered composites for the repair of large osteochondral defects. Arthritis Rheum. 46, 2524, 2002.
13. Loening, A.M., James, I.E., Levenston, M.E., Badger, A. M., Frank, E. H., Kurz, B., Nuttall, M. E., Hung, H. H., Blake, S. M., Grodzinsky, A. J., and Lark, M. W. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Arch. Biochem. Biophys. 381, 205, 2000.
14. Prendergast, P.J., Huiskes, R., and Søballe, K. Biophysical stimuli on cells during tissue differentiation at implant interfaces. J. Biomech. 30, 539, 1997.
15. Lacroix, D., and Prendergast, P.J. A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading. J. Biomech. 35, 1163, 2002.
16. Huiskes, R., van Driel, W.D., Prendergast, P.J., and Søballe, K. A biomechanical regulatory model of periprosthetic tissue differentiation. J. Mater. Sci. Mater. Med. 8, 785, 1997.
17. Kelly, D.J., Prendergast, P.J. Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects. J. Biomech. 38, 1413, 2005.
18. Pauwels, F. Eine neue Theorie über den einfluss mechanischer Reize auf die Differenzierung der Stützgewebe. Z. Anat. Entwickl. 121, 478, 1960.
19. Translated by Maquet, P., Furlong, R., as A new theory concerning the influence of mechanical stimuli in the differentiation of supporting tissues. In: Biomechanics of the Locomotor Apparatus 375, 1980.
20. Carter, D.R., Blenman, P.R., and Beaupré, G.S. Correlations between mechanical stress history and tissue differentiation in initial fracture healing. J. Orthop. Res. 6, 736, 1988.
21. Duda, G.N., Maldonado, Z.M., Klein, P., Heller, M.O.W., Burns, J. and Bail, H. On the influence of mechanical conditions in osteochondral defect healing. J. Biomech. 38, 843, 2005.
22. Loboa, E.G., Wren, T.A.L., Beaupré, G.S., and Carter, D.R. Mechanobiology of soft tissue differentiation-a computational approach of a fiber-reinforced poroelastic model based on homogeneous and isotropic simplifications. Biomech. Model. Mechanobiol. 2, 83, 2003.
23. Claes, L.E., and Heigele, C.A. Magnitudes of local stress and strain along surfaces predict the course and type of fracture healing. J. Biomech. 32, 255, 1999.
24. Gómez-Benito, M.J., Garcia-Aznar, J.M., Kuiper, J.H., and Doblaré, M. Influence of fracture gap size on the pattern of long bone healing: a computational study. J. Theor. Biol. 235, 105, 2005.
25. Søballe, K., Hansen., E.S., B-Rasmussen, H., Jørgensen, P.H., and Bunger, C. Tissue ingrowth into titanium and hydroxyapapite coated implants during stable and unstable mechanical conditions. J. Ortho. Res. 10, 285, 1992.
26. Lacroix, D., Prendergast, P.J., Li, G., and Marsh, D. Biomechanical model to simulate tissue differentiation and bone regeneration: application to fracture healing. Med. Biol. Eng. Comput. 40, 14, 2002.
27. DiSilvestro, M.R., and Suh, J.K. A cross-validation of the biphasic poroviscoelastic model of articular cartilage in unconfined compression, indentation, and confined compression. J. Biomech. 34, 519, 2001.
28. Li, L.P., Buschmann, M.D., and Shirazi-Adl, A. A fibril reinforced nonhomogeneous poroelastic model for articular cartilage: inhomogeneous response in unconfined compression. J. Biomech. 33, 1533, 2000.
29. Bailon-Plaza, A., and van der Meulen, M.C.H. A mathematical framework to study the effects of growth factor influences on fracture healing. J. Theor. Biol. 212, 191, 2001.
30. Mauck, R.L., Nicoll, S.B., Seyhan, S.L., Ateshian, G.A., and Hung, C. T. Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering. Tissue Eng. 9, 597, 2003.
31. Shapiro, F., Koide, S., and Glimcher, M.J. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J. Bone Joint. Surg. 75A, 532, 1993.
32. Metsäranta, M., Kujala, U. M., Pelliniemi, L., Österman, H., Heikki, A., and Vuorio, E. Evidence of insufficient chondrocytic differentiation during repair of full-thickness defects of articular cartilage. Matrix Biol. 15, 39, 1996.
33. Geris, L., Andreykiv, A., Van Oosterwyck, H., Vander Sloten, J., Van Keulen, F., Duyck J., and Naert, I. Numerical simulation of tissue differentiation around loaded titanium implants in a bone chamber. J. Biomechan. 37, 763, 2004.
34. Akizuki, S., Mow, V.C., Müller, F., Pita, J.C., Howell, D.S., and Manicourt, D.H. Tensile properties of human knee joint cartilage: I. Influence of ionic conditions, weight bearing, and fibrillation on tensile modulus. J. Orthop. Res. 4, 379, 1986.
35. Maroudas, A., and Bullough, P. Permeability of articular cartilage. Nature 219, 1260, 1968.
36. Semple, J.L., Woolridge, N., and Lumsden, C.J. In vitro, in vivo, in silico: Computational systems in tissue engineering and regenerative medicine. Tissue Eng. 11, 341, 2005.